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Showing 1 to 12 of 301 entries
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Culture conditions for bovine embryonic stem cell-like cells isolated from blastocysts after external fertilization.

Cytotechnology

Jin M, Wu A, Dorzhin S, Yue Q, Ma Y, Liu D.
PMID: 22438181
Cytotechnology. 2012 Aug;64(4):379-89. doi: 10.1007/s10616-011-9408-z. Epub 2012 Mar 22.

Although isolation and characterization of embryonic stem cells have been successful in cattle, maintenance of bovine embryonic stem cells in culture remains difficult. In this study, we compared different methods of cell passaging, feeder cell layers and medium conditions...

Promoting Effects of Heparin on ex vivo Expansion of Megakaryocytopoiesis from Human Cord Blood CD34+ Cells.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

Maurer AM, Gezer A.
PMID: 24273488
Transfus Med Hemother. 2013 Oct;40(5):344-50. doi: 10.1159/000355519. Epub 2013 Sep 19.

INTRODUCTION: Transfusion of ex vivo expanded megakaryocytes (MKs) has been proposed to sustain platelet recovery after cord blood (CB) hematopoietic stem cell transplantation. In this study, we investigated the effects of heparin on ex vivo colony forming unit-megakaryocytes (CFU-MKs)...

In-vitro Behavior of Human Umbilical Cord Blood Stem Cells Towards Serum Based Minimal Cytokine Growth Conditions.

Indian journal of clinical biochemistry : IJCB

Mantri S, Mohapatra PC.
PMID: 24966475
Indian J Clin Biochem. 2014 Jul;29(3):279-89. doi: 10.1007/s12291-013-0346-8. Epub 2013 May 29.

We tried here to optimize the proliferation of both Hematopoietic and Mesenchymal stem cells of Umbilical Cord blood in minimal cytokine growth condition. Failing to get good results of expansion of non-adherent Hematopoietic Total Nucleated Cells and adherent Fibroblastic...

Cloning of Soluble Human Stem Cell Factor in pET-26b(+) Vector.

Advanced pharmaceutical bulletin

Asghari S, Shekari Khaniani M, Darabi M, Mansoori Derakhshan S.
PMID: 24409415
Adv Pharm Bull. 2014;4(1):91-5. doi: 10.5681/apb.2014.014. Epub 2013 Dec 23.

PURPOSE: Stem cell factor (SCF) plays an important role in the survival, proliferation and differentiation of hematopoietic stem cells and progenitor cells. Potential therapeutic applications of SCF include hematopoietic stem cell mobilization, exvivo stem/progenitor cell expansion, gene therapy, and...

Decreased number of interstitial cells of Cajal play an important role in the declined intestinal transit during cholesterol gallstone formation in guinea pigs fed on high cholesterol diet.

International journal of clinical and experimental medicine

Fan Y, Wu SD, Fu BB, Weng C, Wang XP.
PMID: 24995081
Int J Clin Exp Med. 2014 May 15;7(5):1262-8. eCollection 2014.

To study the changes of interstitial cells of Cajal (ICCs) and expression of c-kt and scf mRNA in terminal ileum tissue during cholesterol gallstone formation in guinea pigs fed on high cholesterol diet, forty guinea pigs were divided into...

The Effects of Imatinib Mesylate on Cellular Viability, Platelet Derived Growth Factor and Stem Cell Factor in Mouse Testicular Normal Leydig Cells.

Journal of reproduction & infertility

Kheradmand F, Hashemnia SM, Valizadeh N, Roshan-Milani S.
PMID: 27141462
J Reprod Infertil. 2016 Apr-Jun;17(2):82-7.

BACKGROUND: Growth factors play an essential role in the development of tumor and normal cells like testicular leydig cells. Treatment of cancer with anti-cancer agents like imatinib mesylate may interfere with normal leydig cell activity, growth and fertility through...

Expression of Epidermal c-Kit+ of Vitiligo Lesions Is Related to Responses to Excimer Laser.

Annals of dermatology

Park OJ, Han JS, Lee SH, Park CS, Won CH, Lee MW, Choi JH, Chang SE.
PMID: 27489428
Ann Dermatol. 2016 Aug;28(4):457-63. doi: 10.5021/ad.2016.28.4.457. Epub 2016 Jul 26.

BACKGROUND: The survival and growth of melanocytes are controlled by the binding of stem cell factor to its cell surface receptor c-kit+ (CD117). We have observed that c-kit+ melanocytes existed in some lesions of vitiligo, while Melan A+ cells...

The protective effects of total phenols in magnolia officinalix rehd. et wils on gastrointestinal tract dysmotility is mainly based on its influence on interstitial cells of cajal.

International journal of clinical and experimental medicine

Tian H, Huang D, Li T, Huang L, Zheng X, Tang D, Zhang L, Wang J.
PMID: 26884941
Int J Clin Exp Med. 2015 Nov 15;8(11):20279-86. eCollection 2015.

Magnolia officinalix Rehd. et Wils is a kind of herb which is widely used for gastrointestinal tract mobility disorder in Asian countries. In this study, we investigated whether the total phenols of Magnolia officinalix Rehd. et Wils (TPM) treatment...

Construction of pPIC9 Recombinant Vector Containing Human Stem Cell Factor.

Advanced pharmaceutical bulletin

Farhadi B, Shekari Khaniani M, Mansoori Derakhshan S.
PMID: 24312852
Adv Pharm Bull. 2013;3(2):303-8. doi: 10.5681/apb.2013.049. Epub 2013 Aug 20.

PURPOSE: Various cytokine regulates hematopoesis; they promote number of stages in stem cells biology such as proliferation, differentiation and endurance. Biological effects of SCF, as a hematopoietic cytokine; is triggered by binding to its ligand c-kit. Potential therapeutic applications...

Are neural crest stem cells the missing link between hematopoietic and neurogenic niches?.

Frontiers in cellular neuroscience

Coste C, Neirinckx V, Gothot A, Wislet S, Rogister B.
PMID: 26136659
Front Cell Neurosci. 2015 Jun 17;9:218. doi: 10.3389/fncel.2015.00218. eCollection 2015.

Hematopoietic niches are defined as cellular and molecular microenvironments that regulate hematopoietic stem cell (HSC) function together with stem cell autonomous mechanisms. Many different cell types have been characterized as contributors to the formation of HSC niches, such as...

Physician Education: The Erythropoietin Receptor and Signal Transduction.

The oncologist

Yoshimura A, Arai K.
PMID: 10388012
Oncologist. 1996;1(5):337-339.

ERYTHROPOIETIN (EPO): Erythropoietin (EPO) is a hormone that promotes the proliferation and differentiation of erythroid progenitor cells and regulates the number of erythrocytes in peripheral blood. EPO is produced mainly by the kidneys, and transcription of the EPO gene...

Analysis of hematopoietic microenvironment containing spatial development of stromal cells in nonwoven fabrics.

Journal of bioscience and bioengineering

Sasaki T, Takagi M, Soma T, Yoshida T.
PMID: 16233486
J Biosci Bioeng. 2003;96(1):76-8.

We previously reported that a 3D coculture system for hematopoietic cells with spatial development of stromal cells in nonwoven fabrics was superior to a conventional 2D coculture system with respect to progenitor expansion and stem cell maintenance. The hematopoietic...

Showing 1 to 12 of 301 entries