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Showing 1 to 12 of 53 entries
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Thermal desorption modulation for comprehensive two-dimensional gas chromatography using a simple and inexpensive segmented-loop fluidic interface.

Talanta

Mucédola V, Vieira LCS, Pierone D, Gobbi AL, Poppi RJ, Hantao LW.
PMID: 28107960
Talanta. 2017 Mar 01;164:470-476. doi: 10.1016/j.talanta.2016.12.005. Epub 2016 Dec 07.

In this study, we introduce a modulation strategy for comprehensive two-dimensional gas chromatography (GC×GC) by using a simple and consumable-free modulator. This "Do-It-Yourself" interface comprised a 1.0m×0.25mm segment of MTX-5 metallic column and a low-cost DC power supply. Thermal...

Neuroanatomical basis for the antidepressant-like effects of the 5-HT(1A) receptor agonists 8-OH-DPAT and ipsapirone in the rat forced swimming test.

Behavioural pharmacology

Schreiber R, De Vry J.
PMID: 11224231
Behav Pharmacol. 1993 Dec;4(6):625-636.

In the rat forced swimming test, systemic application of the serotonin 1A (5-HT(1A)) receptor agonist 8-OH-DPAT reduced immobility (ID(50) 0.17-1.37mg/kg, depending on route of application and application schedule). Intracerebroventricular (i.c.v.) or local application into the dorsal raphe nucleus (DRN),...

Lack of restraint-induced increases of brain serotonin metabolism in rats treated with spiperone: relationship with restraint-induced behavioral deficits.

Pakistan journal of pharmaceutical sciences

Mushtaq F, Haider S, Perveen T, Haleem DJ.
PMID: 16414597
Pak J Pharm Sci. 2004 Jul;17(2):57-65.

Spiperone is a potent dopamine (DA) D2, serotonin (5-hydroxy tryptamine, 5-HT) 5-HT(1A) and 5-HT(2A) antagonist. It is used clinically as an antischizophrenic compound. Previous studies have shown that a downregulation of somatodendritic 5-HT(1A) receptor is involved in adaptation to...

Calcium antagonist flunarizine hydrochloride affects striatal D2 dopamine receptors in the young adult and aged rat brain.

Archives of gerontology and geriatrics

Asanuma M, Ogawa N, Haba K, Hirata H, Mori A.
PMID: 15374420
Arch Gerontol Geriatr. 1991 Nov-Dec;13(3):271-8. doi: 10.1016/0167-4943(91)90049-v.

The calcium (Ca) antagonist flunarizine hydrochloride (FNZ) has been reported to induce parkinsonism, especially in the elderly. The effects of FNZ on dopamine receptors in rat striatal membranes, especially in aged rats, were studied using radiolabeled receptor assay. Similar...

Alterations in central neurotransmitter receptor binding sites following estradiol implantation in female rats.

Neurochemistry international

Goetz C, Bourgoin S, Cesselin F, Brandi A, Bression D, Martinet M, Peillon F, Hamon M.
PMID: 20487964
Neurochem Int. 1983;5(4):375-83. doi: 10.1016/0197-0186(83)90066-9.

The subcutaneous implantation of an estradiol pellet (10 mg) into female rats induced a hypophyseal hyperplasia with hyperprolactinaemia. Examination of neurotransmitter receptors in the hippocampus, striatum and cerebral cortex one month after the implantation revealed that estrogenization was associated...

Fetal substantia nigra and adrenal medullary grafts placed contralateral to the nigrostriatal lesion side induce a decrease in turning behavior but not in dopamine receptor density.

Restorative neurology and neuroscience

Mendoza-Ramírez JL, Aguilar-Roblero R, Zainos-Rosales A, Drucker-Colín R.
PMID: 21551635
Restor Neurol Neurosci. 1991 Jan 01;3(4):177-85. doi: 10.3233/RNN-1991-3402.

Motor asymmetries as well as changes in the density of postsynaptic dopamine receptors produced by unilateral denervation of the striatum have been reduced by both substantia nigra (SN) and adrenal medullary (AM) grafts. Since to this date all studies...

Aspects of neural plasticity in the central nervous system-IV. Chemical anatomical studies on the aging brain.

Neurochemistry international

Zoli M, Benfenati F, Pich EM, Toffano G, Fuxe K, Agnati LF.
PMID: 20504584
Neurochem Int. 1990;16(4):437-49. doi: 10.1016/0197-0186(90)90005-e.

Some effects of aging processes on the neurochemical features of central transmitter-identified neuronal populations have been investigated by means of immunocytochemistry and receptor autoradiographic techniques coupled with image analysis. A selective decrease of tyrosine hydroxylase immunoreactivity in the ventrolateral...

Roles of Non-cholinergic Intrapancreatic Nerves, Serotonergic Nerves, on Pancreatic Exocrine Secretion in the Isolated Perfused Rat Pancreas.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Jiang ZE, Shin BN, Kim IH, Lee HJ, Yong JH, Lee MJ, Won MH, Lee YL.
PMID: 22128264
Korean J Physiol Pharmacol. 2011 Oct;15(5):307-12. doi: 10.4196/kjpp.2011.15.5.307. Epub 2011 Oct 31.

It has been rereported that axons which display 5-hydroxytryptamine (5-HT) immunoreactivity are abundant in the pancreas and the majority of serotonergic axons terminate within intrapancreatic ganglia, islet and acini. This histological result strongly suggests that intrapancreatic serotonergic nerves could...

Diabetes Autoantibodies Mediate Neural- and Endothelial Cell- Inhibitory Effects Via 5-Hydroxytryptamine- 2 Receptor Coupled to Phospholipase C/Inositol Triphosphate/Ca2+ Pathway.

Journal of endocrinology and diabetes

Zimering MB.
PMID: 29805993
J Endocrinol Diabetes. 2017;4(4). doi: 10.15226/2374-6890/4/4/00184. Epub 2017 Oct 04.

AIMS: To identify the G-protein coupled receptor(s) on neuroblastoma and endothelial cells which mediate neural- and endothelial cell-inhibitory effects in plasma autoantibodies from a subset of older type 2 diabetes with neurologic and vascular co-morbidity. To determine the mechanism(s)...

In Vivo Effects of Dopamine and Dopaminergic Antagonists on Testicular Maturation in the Red Swamp Crayfish, Procambarus clarkii.

The Biological bulletin

Sarojini R, Nagabhushanam R, Fingerman M.
PMID: 29244575
Biol Bull. 1995 Dec;189(3):340-346. doi: 10.2307/1542151.

In vivo, dopamine (DA) inhibits testicular maturation in the red swamp crayfish, Procambarus clarkii. Crayfish given DA injections had a smaller testicular index, smaller testicular lobes, fewer mature sperm, and less-well-developed androgenic glands than did the control crayfish given...

Circulating Neurotoxic 5-HT2A Receptor Agonist Autoantibodies in Adult Type 2 Diabetes with Parkinson's Disease.

Journal of endocrinology and diabetes

Zimering MB.
PMID: 29888323
J Endocrinol Diabetes. 2018;5(2). doi: 10.15226/2374-6890/5/2/01102. Epub 2018 May 10.

AIMS: To test whether circulating neurotoxic autoantibodies increase in adult type 2 diabetes mellitus with Parkinson's disease (PD) or dementia. To identify the G-protein coupled receptor on neuroblastoma cells mediating neural inhibitory effects in diabetic Parkinson's disease plasma autoantibodies....

Diabetes Autoantibodies Mediate Neural- and Endothelial Cell- Inhibitory Effects Via 5-Hydroxytryptamine- 2 Receptor Coupled to Phospholipase C/Inositol Triphosphate/Ca2+ Pathway.

Journal of endocrinology and diabetes

Zimering MB.
PMID: 29805993
J Endocrinol Diabetes. 2017;4(4). doi: 10.15226/2374-6890/4/4/00184. Epub 2017 Oct 04.

AIMS: To identify the G-protein coupled receptor(s) on neuroblastoma and endothelial cells which mediate neural- and endothelial cell-inhibitory effects in plasma autoantibodies from a subset of older type 2 diabetes with neurologic and vascular co-morbidity. To determine the mechanism(s)...

Showing 1 to 12 of 53 entries