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Soft TCPTP Agonism-Novel Target to Rescue Airway Epithelial Integrity by Exogenous Spermidine.

Frontiers in pharmacology

Ghisalberti CA, Borzì RM, Cetrullo S, Flamigni F, Cairo G.
PMID: 27375482
Front Pharmacol. 2016 Jun 03;7:147. doi: 10.3389/fphar.2016.00147. eCollection 2016.

A reparative approach of disrupted epithelium in obstructive airway diseases, namely asthma and chronic obstructive pulmonary disease (COPD), may afford protection and long-lasting results compared to conventional therapies, e.g., corticosteroids or immunosuppressant drugs. Here, we propose the polyamine spermidine...

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Ghisalberti CA, Borzì RM, Cetrullo S, et al. Soft TCPTP Agonism-Novel Target to Rescue Airway Epithelial Integrity by Exogenous Spermidine. Front Pharmacol. 2016;7:147doi: 10.3389/fphar.2016.00147.
Ghisalberti, C. A., Borzì, R. M., Cetrullo, S., Flamigni, F., & Cairo, G. (2016). Soft TCPTP Agonism-Novel Target to Rescue Airway Epithelial Integrity by Exogenous Spermidine. Frontiers in pharmacology, 7147. https://doi.org/10.3389/fphar.2016.00147
Ghisalberti, Carlo A, et al. "Soft TCPTP Agonism-Novel Target to Rescue Airway Epithelial Integrity by Exogenous Spermidine." Frontiers in pharmacology vol. 7 (2016): 147. doi: https://doi.org/10.3389/fphar.2016.00147
Ghisalberti CA, Borzì RM, Cetrullo S, Flamigni F, Cairo G. Soft TCPTP Agonism-Novel Target to Rescue Airway Epithelial Integrity by Exogenous Spermidine. Front Pharmacol. 2016 Jun 03;7:147. doi: 10.3389/fphar.2016.00147. eCollection 2016. PMID: 27375482; PMCID: PMC4892113.
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A Cross-Sectional Study: Nutritional Polyamines in Frequently Consumed Foods of the Turkish Population.

Foods (Basel, Switzerland)

Buyukuslu N, Hizli H, Esin K, Garipagaoglu M.
PMID: 28234336
Foods. 2014 Oct 09;3(4):541-557. doi: 10.3390/foods3040541.

Putrescine, spermidine and spermine are the most abundant polycationic natural amines found in nearly all organisms. They are involved in regulation of gene expression, translation, cell proliferation and differentiation. They can be supplied by the endogenous synthesis inside the...

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Buyukuslu N, Hizli H, Esin K, et al. A Cross-Sectional Study: Nutritional Polyamines in Frequently Consumed Foods of the Turkish Population. Foods. 2014;3(4):541-557doi: 10.3390/foods3040541.
Buyukuslu, N., Hizli, H., Esin, K., & Garipagaoglu, M. (2014). A Cross-Sectional Study: Nutritional Polyamines in Frequently Consumed Foods of the Turkish Population. Foods (Basel, Switzerland), 3(4), 541-557. https://doi.org/10.3390/foods3040541
Buyukuslu, Nihal, et al. "A Cross-Sectional Study: Nutritional Polyamines in Frequently Consumed Foods of the Turkish Population." Foods (Basel, Switzerland) vol. 3,4 (2014): 541-557. doi: https://doi.org/10.3390/foods3040541
Buyukuslu N, Hizli H, Esin K, Garipagaoglu M. A Cross-Sectional Study: Nutritional Polyamines in Frequently Consumed Foods of the Turkish Population. Foods. 2014 Oct 09;3(4):541-557. doi: 10.3390/foods3040541. PMID: 28234336; PMCID: PMC5302244.
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From Accumulation to Degradation: Reprogramming Polyamine Metabolism Facilitates Dark-Induced Senescence in Barley Leaf Cells.

Frontiers in plant science

Sobieszczuk-Nowicka E, Kubala S, Zmienko A, Małecka A, Legocka J.
PMID: 26779231
Front Plant Sci. 2016 Jan 06;6:1198. doi: 10.3389/fpls.2015.01198. eCollection 2015.

The aim of this study was to analyze whether polyamine (PA) metabolism is involved in dark-induced Hordeum vulgare L. 'Nagrad' leaf senescence. In the cell, the titer of PAs is relatively constant and is carefully controlled. Senescence-dependent increases in...

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Sobieszczuk-Nowicka E, Kubala S, Zmienko A, et al. From Accumulation to Degradation: Reprogramming Polyamine Metabolism Facilitates Dark-Induced Senescence in Barley Leaf Cells. Front Plant Sci. 2016;6:1198doi: 10.3389/fpls.2015.01198.
Sobieszczuk-Nowicka, E., Kubala, S., Zmienko, A., Małecka, A., & Legocka, J. (2015). From Accumulation to Degradation: Reprogramming Polyamine Metabolism Facilitates Dark-Induced Senescence in Barley Leaf Cells. Frontiers in plant science, 61198. https://doi.org/10.3389/fpls.2015.01198
Sobieszczuk-Nowicka, Ewa, et al. "From Accumulation to Degradation: Reprogramming Polyamine Metabolism Facilitates Dark-Induced Senescence in Barley Leaf Cells." Frontiers in plant science vol. 6 (2015): 1198. doi: https://doi.org/10.3389/fpls.2015.01198
Sobieszczuk-Nowicka E, Kubala S, Zmienko A, Małecka A, Legocka J. From Accumulation to Degradation: Reprogramming Polyamine Metabolism Facilitates Dark-Induced Senescence in Barley Leaf Cells. Front Plant Sci. 2016 Jan 06;6:1198. doi: 10.3389/fpls.2015.01198. eCollection 2015. PMID: 26779231; PMCID: PMC4702279.
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Spermidine is protective against kidney ischemia and reperfusion injury through inhibiting DNA nitration and PARP1 activation.

Anatomy & cell biology

Kim J.
PMID: 29043098
Anat Cell Biol. 2017 Sep;50(3):200-206. doi: 10.5115/acb.2017.50.3.200. Epub 2017 Sep 20.

Kidney ischemia and reperfusion injury (IRI) is associated with a high mortality rate, which is attributed to tubular oxidative and nitrative stresses; however, an effective approach to limit IRI remains elusive. Spermidine, a naturally occurring polyamine, protects yeast cells...

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Kim J. Spermidine is protective against kidney ischemia and reperfusion injury through inhibiting DNA nitration and PARP1 activation. Anat Cell Biol. 2017;50(3):200-206doi: 10.5115/acb.2017.50.3.200.
Kim, J. (2017). Spermidine is protective against kidney ischemia and reperfusion injury through inhibiting DNA nitration and PARP1 activation. Anatomy & cell biology, 50(3), 200-206. https://doi.org/10.5115/acb.2017.50.3.200
Kim, Jinu. "Spermidine is protective against kidney ischemia and reperfusion injury through inhibiting DNA nitration and PARP1 activation." Anatomy & cell biology vol. 50,3 (2017): 200-206. doi: https://doi.org/10.5115/acb.2017.50.3.200
Kim J. Spermidine is protective against kidney ischemia and reperfusion injury through inhibiting DNA nitration and PARP1 activation. Anat Cell Biol. 2017 Sep;50(3):200-206. doi: 10.5115/acb.2017.50.3.200. Epub 2017 Sep 20. PMID: 29043098; PMCID: PMC5639174.
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Design and Characterization of Dicyanovinyl Reactive Dyes for the Colorimetric Detection of Thiols and Biogenic Amines.

Sensors (Basel, Switzerland)

Mastnak T, Lobnik A, Mohr GJ, Turel M.
PMID: 29518001
Sensors (Basel). 2018 Mar 08;18(3). doi: 10.3390/s18030814.

The synthesis of two new azobenzene dyes, namely CR-528 and CR-555, and their spectral properties in ethanol solution are described. The recognition of sulfur-containing analytes (2-mercaptoethanol (2-ME), sodium hydrosulfide (NaHS)), and biogenic amines (spermine, spermidine, ethanolamine) bestowed significant spectral...

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Mastnak T, Lobnik A, Mohr GJ, et al. Design and Characterization of Dicyanovinyl Reactive Dyes for the Colorimetric Detection of Thiols and Biogenic Amines. Sensors (Basel). 2018;18(3)doi: 10.3390/s18030814.
Mastnak, T., Lobnik, A., Mohr, G. J., & Turel, M. (2018). Design and Characterization of Dicyanovinyl Reactive Dyes for the Colorimetric Detection of Thiols and Biogenic Amines. Sensors (Basel, Switzerland), 18(3), . https://doi.org/10.3390/s18030814
Mastnak, Tinkara, et al. "Design and Characterization of Dicyanovinyl Reactive Dyes for the Colorimetric Detection of Thiols and Biogenic Amines." Sensors (Basel, Switzerland) vol. 18,3 (2018). doi: https://doi.org/10.3390/s18030814
Mastnak T, Lobnik A, Mohr GJ, Turel M. Design and Characterization of Dicyanovinyl Reactive Dyes for the Colorimetric Detection of Thiols and Biogenic Amines. Sensors (Basel). 2018 Mar 08;18(3). doi: 10.3390/s18030814. PMID: 29518001; PMCID: PMC5876516.
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Exogenous spermidine alleviates oxidative damage and reduce yield loss in rice submerged at tillering stage.

Frontiers in plant science

Liu M, Chu M, Ding Y, Wang S, Liu Z, Tang S, Ding C, Li G.
PMID: 26583021
Front Plant Sci. 2015 Oct 31;6:919. doi: 10.3389/fpls.2015.00919. eCollection 2015.

To figure out whether spermidine (Spd) can alleviate oxidative damage on rice (Oryza sativa L.) caused by submergence stress, Ningjing 3 was used in this study. The results showed that, spraying Spd on rice leaves at a concentration of...

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Liu M, Chu M, Ding Y, et al. Exogenous spermidine alleviates oxidative damage and reduce yield loss in rice submerged at tillering stage. Front Plant Sci. 2015;6:919doi: 10.3389/fpls.2015.00919.
Liu, M., Chu, M., Ding, Y., Wang, S., Liu, Z., Tang, S., Ding, C., & Li, G. (2015). Exogenous spermidine alleviates oxidative damage and reduce yield loss in rice submerged at tillering stage. Frontiers in plant science, 6919. https://doi.org/10.3389/fpls.2015.00919
Liu, Ming, et al. "Exogenous spermidine alleviates oxidative damage and reduce yield loss in rice submerged at tillering stage." Frontiers in plant science vol. 6 (2015): 919. doi: https://doi.org/10.3389/fpls.2015.00919
Liu M, Chu M, Ding Y, Wang S, Liu Z, Tang S, Ding C, Li G. Exogenous spermidine alleviates oxidative damage and reduce yield loss in rice submerged at tillering stage. Front Plant Sci. 2015 Oct 31;6:919. doi: 10.3389/fpls.2015.00919. eCollection 2015. PMID: 26583021; PMCID: PMC4628117.
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Kinetics and calcium-specificity of polyamine uptake in carrot protoplasts.

Amino acids

Antognoni F, Casali P, Pistocchi R, Bagni N.
PMID: 24189738
Amino Acids. 1994 Oct;6(3):301-9. doi: 10.1007/BF00813750.

The kinetics of putrescine and spermidine uptake and the influence of calcium on the kinetic parameters of the transport process were investigated in protoplasts isolated from carrot phloem parenchyma. Spermidine uptake dependence on external concentration was biphasic, both in...

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Antognoni F, Casali P, Pistocchi R, et al. Kinetics and calcium-specificity of polyamine uptake in carrot protoplasts. Amino Acids. 1994;6(3):301-9doi: 10.1007/BF00813750.
Antognoni, F., Casali, P., Pistocchi, R., & Bagni, N. (1994). Kinetics and calcium-specificity of polyamine uptake in carrot protoplasts. Amino acids, 6(3), 301-9. https://doi.org/10.1007/BF00813750
Antognoni, F, et al. "Kinetics and calcium-specificity of polyamine uptake in carrot protoplasts." Amino acids vol. 6,3 (1994): 301-9. doi: https://doi.org/10.1007/BF00813750
Antognoni F, Casali P, Pistocchi R, Bagni N. Kinetics and calcium-specificity of polyamine uptake in carrot protoplasts. Amino Acids. 1994 Oct;6(3):301-9. doi: 10.1007/BF00813750. PMID: 24189738.
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Determination of biogenic amines by high-performance liquid chromatography (HPLC-DAD) in probiotic cow's and goat's fermented milks and acceptance.

Food science & nutrition

Costa MP, Balthazar CF, Rodrigues BL, Lazaro CA, Silva AC, Cruz AG, Conte Junior CA.
PMID: 25987991
Food Sci Nutr. 2015 May;3(3):172-8. doi: 10.1002/fsn3.200. Epub 2015 Jan 22.

This study evaluated the presence of biogenic amines in fermented cow's and goat's milks containing probiotic bacteria, during the first 10 days of chilled storage (4 ± 2°C), when the probiotic strains are most viable. The overall acceptance of...

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Costa MP, Balthazar CF, Rodrigues BL, et al. Determination of biogenic amines by high-performance liquid chromatography (HPLC-DAD) in probiotic cow's and goat's fermented milks and acceptance. Food Sci Nutr. 2015;3(3):172-8doi: 10.1002/fsn3.200.
Costa, M. P., Balthazar, C. F., Rodrigues, B. L., Lazaro, C. A., Silva, A. C., Cruz, A. G., & Conte Junior, C. A. (2015). Determination of biogenic amines by high-performance liquid chromatography (HPLC-DAD) in probiotic cow's and goat's fermented milks and acceptance. Food science & nutrition, 3(3), 172-8. https://doi.org/10.1002/fsn3.200
Costa, Marion P, et al. "Determination of biogenic amines by high-performance liquid chromatography (HPLC-DAD) in probiotic cow's and goat's fermented milks and acceptance." Food science & nutrition vol. 3,3 (2015): 172-8. doi: https://doi.org/10.1002/fsn3.200
Costa MP, Balthazar CF, Rodrigues BL, Lazaro CA, Silva AC, Cruz AG, Conte Junior CA. Determination of biogenic amines by high-performance liquid chromatography (HPLC-DAD) in probiotic cow's and goat's fermented milks and acceptance. Food Sci Nutr. 2015 May;3(3):172-8. doi: 10.1002/fsn3.200. Epub 2015 Jan 22. PMID: 25987991; PMCID: PMC4431784.
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MicroRNAs, polyamines, and the activities antioxidant enzymes are associated with in vitro rooting in white pine (Pinus strobus L.).

SpringerPlus

Fei Y, Xiao B, Yang M, Ding Q, Tang W.
PMID: 27069836
Springerplus. 2016 Apr 06;5:416. doi: 10.1186/s40064-016-2080-1. eCollection 2016.

Molecular mechanism of in vitro rooting in conifer is not fully understood. After establishment of a regeneration procedure in eastern white pine (Pinus strobus L.) using mature embryos as explants to induce shoot formation on medium containing 3 μM...

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Fei Y, Xiao B, Yang M, et al. MicroRNAs, polyamines, and the activities antioxidant enzymes are associated with in vitro rooting in white pine (Pinus strobus L.). Springerplus. 2016;5:416doi: 10.1186/s40064-016-2080-1.
Fei, Y., Xiao, B., Yang, M., Ding, Q., & Tang, W. (2016). MicroRNAs, polyamines, and the activities antioxidant enzymes are associated with in vitro rooting in white pine (Pinus strobus L.). SpringerPlus, 5416. https://doi.org/10.1186/s40064-016-2080-1
Fei, Yunjun, et al. "MicroRNAs, polyamines, and the activities antioxidant enzymes are associated with in vitro rooting in white pine (Pinus strobus L.)." SpringerPlus vol. 5 (2016): 416. doi: https://doi.org/10.1186/s40064-016-2080-1
Fei Y, Xiao B, Yang M, Ding Q, Tang W. MicroRNAs, polyamines, and the activities antioxidant enzymes are associated with in vitro rooting in white pine (Pinus strobus L.). Springerplus. 2016 Apr 06;5:416. doi: 10.1186/s40064-016-2080-1. eCollection 2016. PMID: 27069836; PMCID: PMC4821849.
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Polyamines Confer Salt Tolerance in Mung Bean (Vigna radiata L.) by Reducing Sodium Uptake, Improving Nutrient Homeostasis, Antioxidant Defense, and Methylglyoxal Detoxification Systems.

Frontiers in plant science

Nahar K, Hasanuzzaman M, Rahman A, Alam MM, Mahmud JA, Suzuki T, Fujita M.
PMID: 27516763
Front Plant Sci. 2016 Jul 28;7:1104. doi: 10.3389/fpls.2016.01104. eCollection 2016.

The physiological roles of PAs (putrescine, spermidine, and spermine) were investigated for their ability to confer salt tolerance (200 mM NaCl, 48 h) in mung bean seedlings (Vigna radiata L. cv. BARI Mung-2). Salt stress resulted in Na toxicity,...

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Nahar K, Hasanuzzaman M, Rahman A, et al. Polyamines Confer Salt Tolerance in Mung Bean (Vigna radiata L.) by Reducing Sodium Uptake, Improving Nutrient Homeostasis, Antioxidant Defense, and Methylglyoxal Detoxification Systems. Front Plant Sci. 2016;7:1104doi: 10.3389/fpls.2016.01104.
Nahar, K., Hasanuzzaman, M., Rahman, A., Alam, M. M., Mahmud, J. A., Suzuki, T., & Fujita, M. (2016). Polyamines Confer Salt Tolerance in Mung Bean (Vigna radiata L.) by Reducing Sodium Uptake, Improving Nutrient Homeostasis, Antioxidant Defense, and Methylglyoxal Detoxification Systems. Frontiers in plant science, 71104. https://doi.org/10.3389/fpls.2016.01104
Nahar, Kamrun, et al. "Polyamines Confer Salt Tolerance in Mung Bean (Vigna radiata L.) by Reducing Sodium Uptake, Improving Nutrient Homeostasis, Antioxidant Defense, and Methylglyoxal Detoxification Systems." Frontiers in plant science vol. 7 (2016): 1104. doi: https://doi.org/10.3389/fpls.2016.01104
Nahar K, Hasanuzzaman M, Rahman A, Alam MM, Mahmud JA, Suzuki T, Fujita M. Polyamines Confer Salt Tolerance in Mung Bean (Vigna radiata L.) by Reducing Sodium Uptake, Improving Nutrient Homeostasis, Antioxidant Defense, and Methylglyoxal Detoxification Systems. Front Plant Sci. 2016 Jul 28;7:1104. doi: 10.3389/fpls.2016.01104. eCollection 2016. PMID: 27516763; PMCID: PMC4964870.
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Spermidine Protects against Oxidative Stress in Inflammation Models Using Macrophages and Zebrafish.

Biomolecules & therapeutics

Jeong JW, Cha HJ, Han MH, Hwang SJ, Lee DS, Yoo JS, Choi IW, Kim S, Kim HS, Kim GY, Hong SH, Park C, Lee HJ, Choi YH.
PMID: 28365977
Biomol Ther (Seoul). 2018 Mar 01;26(2):146-156. doi: 10.4062/biomolther.2016.272.

Spermidine is a naturally occurring polyamine compound that has recently emerged with anti-aging properties and suppresses inflammation and oxidation. However, its mechanisms of action on anti-inflammatory and antioxidant effects have not been fully elucidated. In this study, the potential...

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Jeong JW, Cha HJ, Han MH, et al. Spermidine Protects against Oxidative Stress in Inflammation Models Using Macrophages and Zebrafish. Biomol Ther (Seoul). 2018;26(2):146-156doi: 10.4062/biomolther.2016.272.
Jeong, J. W., Cha, H. J., Han, M. H., Hwang, S. J., Lee, D. S., Yoo, J. S., Choi, I. W., Kim, S., Kim, H. S., Kim, G. Y., Hong, S. H., Park, C., Lee, H. J., & Choi, Y. H. (2018). Spermidine Protects against Oxidative Stress in Inflammation Models Using Macrophages and Zebrafish. Biomolecules & therapeutics, 26(2), 146-156. https://doi.org/10.4062/biomolther.2016.272
Jeong, Jin-Woo, et al. "Spermidine Protects against Oxidative Stress in Inflammation Models Using Macrophages and Zebrafish." Biomolecules & therapeutics vol. 26,2 (2018): 146-156. doi: https://doi.org/10.4062/biomolther.2016.272
Jeong JW, Cha HJ, Han MH, Hwang SJ, Lee DS, Yoo JS, Choi IW, Kim S, Kim HS, Kim GY, Hong SH, Park C, Lee HJ, Choi YH. Spermidine Protects against Oxidative Stress in Inflammation Models Using Macrophages and Zebrafish. Biomol Ther (Seoul). 2018 Mar 01;26(2):146-156. doi: 10.4062/biomolther.2016.272. PMID: 28365977; PMCID: PMC5839493.
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Fruit metabolite networks in engineered and non-engineered tomato genotypes reveal fluidity in a hormone and agroecosystem specific manner.

Metabolomics : Official journal of the Metabolomic Society

Fatima T, Sobolev AP, Teasdale JR, Kramer M, Bunce J, Handa AK, Mattoo AK.
PMID: 27330523
Metabolomics. 2016;12:103. doi: 10.1007/s11306-016-1037-2. Epub 2016 May 11.

INTRODUCTION: Metabolomics provides a view of endogenous metabolic patterns not only during plant growth, development and senescence but also in response to genetic events, environment and disease. The effects of the field environment on plant hormone-specific metabolite profiles are...

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Fatima T, Sobolev AP, Teasdale JR, et al. Fruit metabolite networks in engineered and non-engineered tomato genotypes reveal fluidity in a hormone and agroecosystem specific manner. Metabolomics. 2016;12:103doi: 10.1007/s11306-016-1037-2.
Fatima, T., Sobolev, A. P., Teasdale, J. R., Kramer, M., Bunce, J., Handa, A. K., & Mattoo, A. K. (2016). Fruit metabolite networks in engineered and non-engineered tomato genotypes reveal fluidity in a hormone and agroecosystem specific manner. Metabolomics : Official journal of the Metabolomic Society, 12103. https://doi.org/10.1007/s11306-016-1037-2
Fatima, Tahira, et al. "Fruit metabolite networks in engineered and non-engineered tomato genotypes reveal fluidity in a hormone and agroecosystem specific manner." Metabolomics : Official journal of the Metabolomic Society vol. 12 (2016): 103. doi: https://doi.org/10.1007/s11306-016-1037-2
Fatima T, Sobolev AP, Teasdale JR, Kramer M, Bunce J, Handa AK, Mattoo AK. Fruit metabolite networks in engineered and non-engineered tomato genotypes reveal fluidity in a hormone and agroecosystem specific manner. Metabolomics. 2016;12:103. doi: 10.1007/s11306-016-1037-2. Epub 2016 May 11. PMID: 27330523; PMCID: PMC4869742.
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Showing 1 to 12 of 727 entries