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Showing 1 to 11 of 11 entries
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The Effects of Altered Membrane Cholesterol Levels on Sodium Pump Activity in Subclinical Hypothyroidism.

Endocrinology and metabolism (Seoul, Korea)

Roy S, Dasgupta A.
PMID: 28256112
Endocrinol Metab (Seoul). 2017 Mar;32(1):129-139. doi: 10.3803/EnM.2017.32.1.129. Epub 2017 Feb 28.

BACKGROUND: Metabolic dysfunctions characteristic of overt hypothyroidism (OH) start at the early stage of subclinical hypothyroidism (SCH). Na⁺/K⁺-ATPase (the sodium pump) is a transmembrane enzyme that plays a vital role in cellular activities in combination with membrane lipids. We...

Association between a novel G94A single nucleotide polymorphism in .

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Abosheasha MA, Zahran F, Bessa SS, El-Magd MA, Mohamed TM.
PMID: 31523248
J Res Med Sci. 2019 Jul 24;24:62. doi: 10.4103/jrms.JRMS_975_18. eCollection 2019.

BACKGROUND: NaMATERIALS AND METHODS: A total number of 150 individuals were subclassified into healthy controls (RESULTS: The biochemical results exhibited a significant reduction in fasting C-Peptide and activity of NaCONCLUSION: Thus, allele A of G94A SNP (rs1060366) could be...

Cytotoxic effect of carbohydrate derivatives of digitoxigenin involves modulation of plasma membrane Ca.

Journal of cellular biochemistry

Valadares JMM, Bajaj SO, Li H, Wang HL, Silva SC, Garcia IJP, Pereira DG, Azalim P, Quintas LEM, Noël F, Cortes VF, O'Doherty GA, Barbosa LA.
PMID: 34553411
J Cell Biochem. 2021 Dec;122(12):1903-1914. doi: 10.1002/jcb.30150. Epub 2021 Sep 22.

Cardiac glycosides, such as digoxin and digitoxin, are compounds that interact with Na

Does Src Kinase Mediated Vasoconstriction Impair Penumbral Reperfusion?.

Stroke

Guldbrandsen HO, Staehr C, Iversen NK, Postnov DD, Matchkov VV.
PMID: 33947213
Stroke. 2021 Jun;52(6):e250-e258. doi: 10.1161/STROKEAHA.120.032737. Epub 2021 May 05.

Despite successful recanalization, a significant number of patients with ischemic stroke experience impaired local brain tissue reperfusion with adverse clinical outcome. The cause and mechanism of this multifactorial complication are yet to be understood. At the current moment, major...

"Oxygen Sensing" by Na,K-ATPase: These Miraculous Thiols.

Frontiers in physiology

Bogdanova A, Petrushanko IY, Hernansanz-Agustín P, Martínez-Ruiz A.
PMID: 27531981
Front Physiol. 2016 Aug 02;7:314. doi: 10.3389/fphys.2016.00314. eCollection 2016.

Control over the Na,K-ATPase function plays a central role in adaptation of the organisms to hypoxic and anoxic conditions. As the enzyme itself does not possess O2 binding sites its "oxygen-sensitivity" is mediated by a variety of redox-sensitive modifications...

Oxidant/antioxidant status in Type-2 diabetes mellitus patients with metabolic syndrome.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Najafi A, Pourfarzam M, Zadhoush F.
PMID: 34084185
J Res Med Sci. 2021 Jan 28;26:6. doi: 10.4103/jrms.JRMS_249_20. eCollection 2021.

BACKGROUND: The concurrence of metabolic syndrome (MS) and diabetes mellitus (DM) is increasing worldwide. The long-term complications of these chronic diseases are a threat to patients' well-being. Oxidative stress is involved in the pathogenesis of several diseases. To understand...

Cytotoxic effect of carbohydrate derivatives of digitoxigenin involves modulation of plasma membrane Ca.

Journal of cellular biochemistry

Valadares JMM, Bajaj SO, Li H, Wang HL, Silva SC, Garcia IJP, Pereira DG, Azalim P, Quintas LEM, Noël F, Cortes VF, O'Doherty GA, Barbosa LA.
PMID: 34553411
J Cell Biochem. 2021 Dec;122(12):1903-1914. doi: 10.1002/jcb.30150. Epub 2021 Sep 22.

Cardiac glycosides, such as digoxin and digitoxin, are compounds that interact with Na

The Slow Dynamics of Intracellular Sodium Concentration Increase the Time Window of Neuronal Integration: A Simulation Study.

Frontiers in computational neuroscience

Zylbertal A, Yarom Y, Wagner S.
PMID: 28970791
Front Comput Neurosci. 2017 Sep 20;11:85. doi: 10.3389/fncom.2017.00085. eCollection 2017.

Changes in intracellular Na

ATP1A3-Related Disorders: An Ever-Expanding Clinical Spectrum.

Frontiers in neurology

Salles PA, Mata IF, Brünger T, Lal D, Fernandez HH.
PMID: 33868146
Front Neurol. 2021 Apr 01;12:637890. doi: 10.3389/fneur.2021.637890. eCollection 2021.

The Na+/K+ ATPases are Sodium-Potassium exchanging pumps, with a heteromeric α-β-γ protein complex. The α3 isoform is required as a rescue pump, after repeated action potentials, with a distribution predominantly in neurons of the central nervous system. This isoform...

Cytotoxic effect of carbohydrate derivatives of digitoxigenin involves modulation of plasma membrane Ca.

Journal of cellular biochemistry

Valadares JMM, Bajaj SO, Li H, Wang HL, Silva SC, Garcia IJP, Pereira DG, Azalim P, Quintas LEM, Noël F, Cortes VF, O'Doherty GA, Barbosa LA.
PMID: 34553411
J Cell Biochem. 2021 Dec;122(12):1903-1914. doi: 10.1002/jcb.30150. Epub 2021 Sep 22.

Cardiac glycosides, such as digoxin and digitoxin, are compounds that interact with Na

Does Src Kinase Mediated Vasoconstriction Impair Penumbral Reperfusion?.

Stroke

Guldbrandsen HO, Staehr C, Iversen NK, Postnov DD, Matchkov VV.
PMID: 33947213
Stroke. 2021 Jun;52(6):e250-e258. doi: 10.1161/STROKEAHA.120.032737. Epub 2021 May 05.

Despite successful recanalization, a significant number of patients with ischemic stroke experience impaired local brain tissue reperfusion with adverse clinical outcome. The cause and mechanism of this multifactorial complication are yet to be understood. At the current moment, major...

Showing 1 to 11 of 11 entries