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Signaling and Transcription Factors during Inner Ear Development: The Generation of Hair Cells and Otic Neurons.

Frontiers in cell and developmental biology

Gálvez H, Abelló G, Giraldez F.
PMID: 28393066
Front Cell Dev Biol. 2017 Mar 24;5:21. doi: 10.3389/fcell.2017.00021. eCollection 2017.

Integration between cell signals and bHLH transcription factors plays a prominent role during the development of hair cells of the inner ear. Hair cells are the sensory receptors of the inner ear, responsible for the mechano-transduction of sound waves...

Role of Cancer Stem Cell, Apoptotic Factor, DNA Repair, and Telomerase Toward Radiation Therapy Response in Stage IIIB Cervical Cancer.

Oman medical journal

Rachmadi L, Siregar NC, Kanoko M, Andrijono A, Bardosono S, Suryandari DA, Sekarutami SM, Hernowo BS.
PMID: 31110630
Oman Med J. 2019 May;34(3):224-230. doi: 10.5001/omj.2019.43.

OBJECTIVES: Cancer stem cells are involved in radioresistant cancers. Transcription factors Sry-related HMG box (SOX2) and octamer binding transcription factor 4 (OCT4) can confer pluripotent cell characteristics and self-renewal ability and are involved in carcinogenesis, metastasis, tumor recurrence, and...

Anti-SOX1 Antibodies in Paraneoplastic Neurological Syndrome.

Journal of clinical neurology (Seoul, Korea)

Sun X, Tan J, Sun H, Liu Y, Guan W, Jia J, Wang Z.
PMID: 33029958
J Clin Neurol. 2020 Oct;16(4):530-546. doi: 10.3988/jcn.2020.16.4.530.

Anti-Sry-like high mobility group box (SOX) 1 antibodies (abs) are partly characterized onconeural autoantibodies (autoabs) due to their correlation with neoplastic diseases. Anti-SOX1 abs are associated with various clinical manifestations, including Lambert-Eaton myasthenic syndrome (LEMS) and paraneoplastic cerebellar degeneration...

Showing 1 to 3 of 3 entries