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Showing 1 to 12 of 15 entries
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In vitro regulation of sheep ovarian surface epithelium (OSE) proliferation by local ovarian factors.

Saudi journal of biological sciences

Saddick SY.
PMID: 23961188
Saudi J Biol Sci. 2012 Jul;19(3):285-90. doi: 10.1016/j.sjbs.2012.03.003. Epub 2012 Mar 30.

The ovarian surface epithelium (OSE) forms a lining around the entire ovary and actively participates in the ovulatory cycle. To investigate how specific growth factors and hormones affect OSE proliferation, the present study used sheep as a model to...

Glycoprotein G-protein Coupled Receptors in Disease: Luteinizing Hormone Receptors and Follicle Stimulating Hormone Receptors.

Diseases (Basel, Switzerland)

Althumairy D, Zhang X, Baez N, Barisas G, Roess DA, Bousfield GR, Crans DC.
PMID: 32942611
Diseases. 2020 Sep 15;8(3). doi: 10.3390/diseases8030035.

Signal transduction by luteinizing hormone receptors (LHRs) and follicle-stimulating hormone receptors (FSHRs) is essential for the successful reproduction of human beings. Both receptors and the thyroid-stimulating hormone receptor are members of a subset of G-protein coupled receptors (GPCRs) described...

Rescue of Cell Surface Expression and Signaling of Mutant Follicle-Stimulating Hormone Receptors.

Endocrinology

Hanyroup S, Anderson RC, Nataraja S, Yu HN, Millar RP, Newton CL.
PMID: 34192304
Endocrinology. 2021 Dec 01;162(12). doi: 10.1210/endocr/bqab134.

Mutations in G protein-coupled receptors (GPCRs) underlie numerous diseases. Many cause receptor misfolding and failure to reach the cell surface. Pharmacological chaperones are cell-permeant small molecules that engage nascent mutant GPCRs in the endoplasmic reticulum, stabilizing folding and "rescuing"...

Ectopic expression of follicle-stimulating hormone receptors in thyroid tumors.

Archives of medical science : AMS

Pawlikowski M, Jaranowska M, Pisarek H, Kubiak R, Fuss-Chmielewska J, Winczyk K.
PMID: 26788096
Arch Med Sci. 2015 Dec 10;11(6):1314-7. doi: 10.5114/aoms.2015.56357. Epub 2015 Dec 11.

INTRODUCTION: In normal conditions follicle-stimulating hormone receptors (FSHR) are expressed in the ovary and the testis. They can also be expressed in gonadal tumors. However, recently we have found FSHR immunostaining in pituitary adenomas, adrenal tumors and neuroendocrine tumors...

Discovery and Development of Small Molecule Allosteric Modulators of Glycoprotein Hormone Receptors.

Frontiers in endocrinology

Nataraja SG, Yu HN, Palmer SS.
PMID: 26441832
Front Endocrinol (Lausanne). 2015 Sep 14;6:142. doi: 10.3389/fendo.2015.00142. eCollection 2015.

Glycoprotein hormones, follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid-stimulating hormone (TSH) are heterodimeric proteins with a common α-subunit and hormone-specific β-subunit. These hormones are dominant regulators of reproduction and metabolic processes. Receptors for the glycoprotein hormones belong to...

Hematopoietic-Prostaglandin D2 synthase through PGD2 production is involved in the adult ovarian physiology.

Journal of ovarian research

Farhat A, Philibert P, Sultan C, Poulat F, Boizet-Bonhoure B.
PMID: 21352547
J Ovarian Res. 2011 Feb 25;4:3. doi: 10.1186/1757-2215-4-3.

BACKGROUND: The prostaglandin D2 (PGD2) pathway is involved in numerous biological processes and while it has been identified as a partner of the embryonic sex determining male cascade, the roles it plays in ovarian function remain largely unknown. PGD2...

Expression of follicle stimulating hormone receptors (FSHR) in thyroid tumours - a marker of malignancy?.

Thyroid research

Pawlikowski M, Fuss-Chmielewska J, Jaranowska M, Pisarek H, Kubiak R, Winczyk K.
PMID: 25685198
Thyroid Res. 2015 Feb 05;8(1):1. doi: 10.1186/s13044-015-0014-6. eCollection 2015.

BACKGROUND: In normal conditions FSHR are expressed in granulosa cells of the ovary and Sertoli cells of the testis. They can be expressed also in gonadal tumours. However, recently the expression of FSHR was found in tumoral cells and...

Ovarian torsion and spontaneous ovarian hyperstimulation syndrome in a twin pregnancy: A case report.

International journal of surgery case reports

Gil Navarro N, Garcia Grau E, Pina Pérez S, Ribot Luna L.
PMID: 28371633
Int J Surg Case Rep. 2017;34:66-68. doi: 10.1016/j.ijscr.2017.03.014. Epub 2017 Mar 15.

INTRODUCTION: Ovarian hyperstimulation syndrome (OHSS) is extremely rare in spontaneous pregnancies. Spontaneous OHSS can result from glycoprotein hormones stimulating follicle-stimulating hormone receptors (FSHR).PRESENTATION OF CASE: We report a twin pregnancy in which ovarian torsion and hemoperitoneum complicating OHSS were...

Gonadotropins and their paracrine signaling network in the zebrafish ovary.

Fish physiology and biochemistry

Ge W.
PMID: 20035460
Fish Physiol Biochem. 2005 Apr;31(2):209-14. doi: 10.1007/s10695-006-0026-1.

Pituitary gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), play fundamental roles in vertebrate ovarian development and function. However, there has been an increasing body of evidence that the actions of FSH and LH are mediated or modulated by...

Follicle stimulating hormone modulates ovarian stem cells through alternately spliced receptor variant FSH-R3.

Journal of ovarian research

Patel H, Bhartiya D, Parte S, Gunjal P, Yedurkar S, Bhatt M.
PMID: 23870332
J Ovarian Res. 2013 Jul 20;6:52. doi: 10.1186/1757-2215-6-52. eCollection 2013.

BACKGROUND: We have earlier reported that follicle stimulating hormone (FSH) modulates ovarian stem cells which include pluripotent, very small embryonic-like stem cells (VSELs) and their immediate descendants 'progenitors' termed ovarian germ stem cells (OGSCs), lodged in adult mammalian ovarian...

Gonadotropin treatment augments postnatal oogenesis and primordial follicle assembly in adult mouse ovaries?.

Journal of ovarian research

Bhartiya D, Sriraman K, Gunjal P, Modak H.
PMID: 23134576
J Ovarian Res. 2012 Nov 07;5(1):32. doi: 10.1186/1757-2215-5-32.

BACKGROUND: Follicle stimulating hormone (FSH) exerts action on both germline and somatic compartment in both ovary and testis although FSH receptors (FSHR) are localized only on the somatic cells namely granulosa cells of growing follicles and Sertoli cells in...

Profile of follicle-stimulating hormone and polymorphism of follicle-stimulating hormone receptor in Madrasin cattle with ovarian hypofunction.

Veterinary world

Utomo B, Putranto ED, Fadholly A.
PMID: 32636582
Vet World. 2020 May;13(5):879-883. doi: 10.14202/vetworld.2020.879-883. Epub 2020 May 11.

BACKGROUND AND AIM: The follicle-stimulating hormone (FSH) gene is an essential regulator of fertility in livestock. This study aims to provide information on the genetic makeup of Madrasin cattle experiencing hypofunction by the FSH profile and FSH receptors (FSHR)...

Showing 1 to 12 of 15 entries