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Showing 1 to 12 of 64 entries
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ER.

Journal of clinical & cellular immunology

Huber S.
PMID: 26925301
J Clin Cell Immunol. 2015;6(6):1-9. doi: 10.4172/2155-9899.1000372.

OBJECTIVES: Coxsackievirus B3 (CVB3) induced myocarditis is sex dependent with males developing more severe disease than females. Previous studies had shown that sex-associated hormones determine the sex bias with testosterone and progesterone promoting myocarditis while estrogen (E2) is protective....

Exon deletions and variants of human estrogen receptor mRNA in endometrial hyperplasia and adenocarcinoma.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Horvath G, Leser G, Hahlin M, Henriksson M.
PMID: 11240664
Int J Gynecol Cancer. 2000 Mar;10(2):128-136. doi: 10.1046/j.1525-1438.2000.00009.x.

Estrogen receptors (estrogen receptor alpha, ER) belong to a family of ligand-modulated transcription factors that play an important role in the progression of such tumors as breast and endometrial cancers. Functional domains, a set of mutations and variants produced...

Clinicopathologic significance of molecular classification of breast cancer: relation to nottingham prognosis index.

Journal of the Egyptian National Cancer Institute

Adly S, Hewedi IH, Mokhtar NM.
PMID: 21863072
J Egypt Natl Canc Inst. 2010 Dec;22(4):209-15.

PURPOSE: The aim of this work is to determine the possible relationship between the different profiles of molecular expression of hormone receptors and Her-2÷neu receptors to clinical and histopathological known prognostic variables for breast cancer.MATERIALS AND METHODS: A total...

Effects of ginseng on two main sex steroid hormone receptors: estrogen and androgen receptors.

Journal of ginseng research

Park J, Song H, Kim SK, Lee MS, Rhee DK, Lee Y.
PMID: 28413327
J Ginseng Res. 2017 Apr;41(2):215-221. doi: 10.1016/j.jgr.2016.08.005. Epub 2016 Aug 23.

Ginseng has been used in China for at least two millennia and is now popular in over 35 countries. It is one of the world's popular herbs for complementary and alternative medicine and has been shown to have helpful...

Breast Cancer: A Molecularly Heterogenous Disease Needing Subtype-Specific Treatments.

Medical sciences (Basel, Switzerland)

Testa U, Castelli G, Pelosi E.
PMID: 32210163
Med Sci (Basel). 2020 Mar 23;8(1). doi: 10.3390/medsci8010018.

Breast cancer is the most commonly occurring cancer in women. There were over two-million new cases in world in 2018. It is the second leading cause of death from cancer in western countries. At the molecular level, breast cancer...

Alpha estrogen receptor polymorphisms and their association with breast density.

Revista medica del Instituto Mexicano del Seguro Social

Vega-García S, Saucedo-García R, Basurto-Acevedo ML, Vargas-Gutiérrez C, Galván-Duarte RE, Reyes-Maldonado E, Aguilar-Gallegos UI, Avelar-Garnica F, Galván-Plata ME.
PMID: 34695312
Rev Med Inst Mex Seguro Soc. 2020 Apr 27;58:S13-S20. doi: 10.24875/RMIMSS.M20000111.

BACKGROUND: In the development of breast cancer (BC), estrogen exposure and the increase in breast density (BD) are two determinant factors for BC risk.OBJECTIVE: To identify the relationship between the XbaI and PvuII polymorphisms in the estrogen receptor (ER-alpha)...

Repression of the transcriptional activity of ERRα with sequence-specific DNA-binding polyamides.

Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents

Chen CY, Li Y, Jia T, He L, Hare AA, Silberstein A, Gallagher J, Martinez TF, Stiles JW, Olenyuk B, Dervan PB, Stiles BL.
PMID: 34552311
Med Chem Res. 2020 Apr;29(4):607-616. doi: 10.1007/s00044-019-02493-4. Epub 2020 Feb 26.

The orphan nuclear receptors estrogen-related receptors (ERRs) bind to the estrogen-related receptor response element (ERRE) to regulate transcriptional programs in cellular metabolism and cancer cell growth. In this study, we evaluated the potential for a pyrrole-imidazole polyamide to block...

Progress: Targeted Therapy, Immunotherapy, and New Chemotherapy Strategies in Advanced Triple-Negative Breast Cancer.

Cancer management and research

Shi J, Liu F, Song Y.
PMID: 33061626
Cancer Manag Res. 2020 Sep 30;12:9375-9387. doi: 10.2147/CMAR.S272685. eCollection 2020.

Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer, accounting for approximately 15% of cases, and is defined by the lack of expression of hormone receptors (estrogen and progesterone receptors) and lack of amplification...

Sexual Dimorphism in the Regulation of Estrogen, Progesterone, and Androgen Receptors by Sex Steroids in the Rat Airway Smooth Muscle Cells.

International journal of endocrinology

Zarazúa A, González-Arenas A, Ramírez-Vélez G, Bazán-Perkins B, Guerra-Araiza C, Campos-Lara MG.
PMID: 27110242
Int J Endocrinol. 2016;2016:8423192. doi: 10.1155/2016/8423192. Epub 2016 Mar 24.

The role of sex hormones in lung is known. The three main sex steroid receptors, estrogen, progesterone, and androgen, have not been sufficiently studied in airway smooth muscle cells (ASMC), and the sex hormone regulation on these receptors is...

Application of Synthetic Polymeric Scaffolds in Breast Cancer 3D Tissue Cultures and Animal Tumor Models.

International journal of biomaterials

Rijal G, Bathula C, Li W.
PMID: 29599800
Int J Biomater. 2017;2017:8074890. doi: 10.1155/2017/8074890. Epub 2017 Dec 17.

Preparation of three-dimensional (3D) porous scaffolds from synthetic polymers is a challenge to most laboratories conducting biomedical research. Here, we present a handy and cost-effective method to fabricate polymeric hydrogel and porous scaffolds using poly(lactic-co-glycolic) acid (PLGA) or polycaprolactone...

Activation of Inflammatory Responses Correlate With Hedgehog Activation and Precede Expansion of Cancer Stem-Like Cells in an Animal Model of Residual Triple Negative Breast Cancer after Neoadjuvant Chemotherapy.

Cancer studies and molecular medicine : open journal

Arnold KM, Flynn NJ, Sims-Mourtada J.
PMID: 28203638
Cancer Stud Mol Med. 2015;2(2):80-86. doi: 10.17140/CSMMOJ-2-112. Epub 2015 Dec 07.

Triple Negative Breast Cancer (TNBC) is characterized as a lack of expression of the hormonal receptors, estrogen and progesterone, and Human epidermal growth factor receptor 2 (HER2) and as such is unresponsive to current targeted therapy. Resistance of breast...

Progesterone receptor action: defining a role in breast cancer.

Expert review of endocrinology & metabolism

Daniel AR, Hagan CR, Lange CA.
PMID: 21857868
Expert Rev Endocrinol Metab. 2011 May 01;6(3):359-369. doi: 10.1586/eem.11.25.

The ovarian steroid hormones, estradiol and progesterone, and their nuclear receptors (estrogen receptor [ER] and progesterone receptor [PR]), are involved in breast cancer development. As ER-positive/PR-positive tumors progress, they are likely to become steroid hormone-resistant/independent, yet often retain expression...

Showing 1 to 12 of 64 entries