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Showing 1 to 7 of 7 entries
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Northern Ring Conformation of Methanocarba-Adenosine 5'-Triphosphate Required for Activation of P2X Receptors.

Drug development research

Dunn PM, Kim HS, Jacobson KA, Burnstock G.
PMID: 22833693
Drug Dev Res. 2004 Apr;61(4):227-232. doi: 10.1002/ddr.10381. Epub 2004 Sep 22.

Strategy, Management and Health PolicyEnabling Technology, Genomics, ProteomicsPreclinical ResearchPreclinical Development Toxicology, Formulation Drug Delivery, PharmacokineticsClinical Development Phases I-III Regulatory, Quality, ManufacturingPostmarketing Phase IVReplacement of the ribose moiety of adenosine 5'-triphosphate (ATP) with a carbocyclic ring constrained in either the...

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Dunn PM, Kim HS, Jacobson KA, et al. Northern Ring Conformation of Methanocarba-Adenosine 5'-Triphosphate Required for Activation of P2X Receptors. Drug Dev Res. 2004;61(4):227-232doi: 10.1002/ddr.10381.
Dunn, P. M., Kim, H. S., Jacobson, K. A., & Burnstock, G. (2004). Northern Ring Conformation of Methanocarba-Adenosine 5'-Triphosphate Required for Activation of P2X Receptors. Drug development research, 61(4), 227-232. https://doi.org/10.1002/ddr.10381
Dunn, Philip M, et al. "Northern Ring Conformation of Methanocarba-Adenosine 5'-Triphosphate Required for Activation of P2X Receptors." Drug development research vol. 61,4 (2004): 227-232. doi: https://doi.org/10.1002/ddr.10381
Dunn PM, Kim HS, Jacobson KA, Burnstock G. Northern Ring Conformation of Methanocarba-Adenosine 5'-Triphosphate Required for Activation of P2X Receptors. Drug Dev Res. 2004 Apr;61(4):227-232. doi: 10.1002/ddr.10381. Epub 2004 Sep 22. PMID: 22833693; PMCID: PMC3402081.
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Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Park JY, Chae S, Kim CS, Kim YJ, Yi HJ, Han E, Joo Y, Hong S, Yun JW, Kim H, Shin KH.
PMID: 31680765
Korean J Physiol Pharmacol. 2019 Nov;23(6):427-448. doi: 10.4196/kjpp.2019.23.6.427. Epub 2019 Oct 24.

Nociceptin/orphanin FQ (N/OFQ) and its receptor, nociceptin opioid peptide (NOP) receptor, are localized in brain areas implicated in depression including the amygdala, bed nucleus of the stria terminalis, habenula, and monoaminergic nuclei in the brain stem. N/OFQ inhibits neuronal...

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Park JY, Chae S, Kim CS, et al. Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists. Korean J Physiol Pharmacol. 2019;23(6):427-448doi: 10.4196/kjpp.2019.23.6.427.
Park, J. Y., Chae, S., Kim, C. S., Kim, Y. J., Yi, H. J., Han, E., Joo, Y., Hong, S., Yun, J. W., Kim, H., & Shin, K. H. (2019). Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 23(6), 427-448. https://doi.org/10.4196/kjpp.2019.23.6.427
Park, Jong Yung, et al. "Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists." The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology vol. 23,6 (2019): 427-448. doi: https://doi.org/10.4196/kjpp.2019.23.6.427
Park JY, Chae S, Kim CS, Kim YJ, Yi HJ, Han E, Joo Y, Hong S, Yun JW, Kim H, Shin KH. Role of nociceptin/orphanin FQ and nociceptin opioid peptide receptor in depression and antidepressant effects of nociceptin opioid peptide receptor antagonists. Korean J Physiol Pharmacol. 2019 Nov;23(6):427-448. doi: 10.4196/kjpp.2019.23.6.427. Epub 2019 Oct 24. PMID: 31680765; PMCID: PMC6819898.
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Getting the balance right: Established and emerging therapies for major depressive disorders.

Neuropsychiatric disease and treatment

Perović B, Jovanović M, Miljković B, Vezmar S.
PMID: 20856599
Neuropsychiatr Dis Treat. 2010 Sep 07;6:343-64. doi: 10.2147/ndt.s10485.

Major depressive disorder (MDD) is a common and serious illness of our times, associated with monoamine deficiency in the brain. Moreover, increased levels of cortisol, possibly caused by stress, may be related to depression. In the treatment of MDD,...

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Perović B, Jovanović M, Miljković B, et al. Getting the balance right: Established and emerging therapies for major depressive disorders. Neuropsychiatr Dis Treat. 2010;6:343-64doi: 10.2147/ndt.s10485.
Perović, B., Jovanović, M., Miljković, B., & Vezmar, S. (2010). Getting the balance right: Established and emerging therapies for major depressive disorders. Neuropsychiatric disease and treatment, 6343-64. https://doi.org/10.2147/ndt.s10485
Perović, Bojana, et al. "Getting the balance right: Established and emerging therapies for major depressive disorders." Neuropsychiatric disease and treatment vol. 6 (2010): 343-64. doi: https://doi.org/10.2147/ndt.s10485
Perović B, Jovanović M, Miljković B, Vezmar S. Getting the balance right: Established and emerging therapies for major depressive disorders. Neuropsychiatr Dis Treat. 2010 Sep 07;6:343-64. doi: 10.2147/ndt.s10485. PMID: 20856599; PMCID: PMC2938284.
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Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions.

International journal for parasitology. Drugs and drug resistance

Kotze AC, Hunt PW, Skuce P, von Samson-Himmelstjerna G, Martin RJ, Sager H, Krücken J, Hodgkinson J, Lespine A, Jex AR, Gilleard JS, Beech RN, Wolstenholme AJ, Demeler J, Robertson AP, Charvet CL, Neveu C, Kaminsky R, Rufener L, Alberich M, Menez C, Prichard RK.
PMID: 25516826
Int J Parasitol Drugs Drug Resist. 2014 Aug 13;4(3):164-84. doi: 10.1016/j.ijpddr.2014.07.007. eCollection 2014 Dec.

Anthelmintic resistance has a great impact on livestock production systems worldwide, is an emerging concern in companion animal medicine, and represents a threat to our ongoing ability to control human soil-transmitted helminths. The Consortium for Anthelmintic Resistance and Susceptibility...

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Kotze AC, Hunt PW, Skuce P, et al. Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions. Int J Parasitol Drugs Drug Resist. 2014;4(3):164-84doi: 10.1016/j.ijpddr.2014.07.007.
Kotze, A. C., Hunt, P. W., Skuce, P., von Samson-Himmelstjerna, G., Martin, R. J., Sager, H., Krücken, J., Hodgkinson, J., Lespine, A., Jex, A. R., Gilleard, J. S., Beech, R. N., Wolstenholme, A. J., Demeler, J., Robertson, A. P., Charvet, C. L., Neveu, C., Kaminsky, R., Rufener, L., Alberich, M., Menez, C., & Prichard, R. K. (2014). Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions. International journal for parasitology. Drugs and drug resistance, 4(3), 164-84. https://doi.org/10.1016/j.ijpddr.2014.07.007
Kotze, Andrew C, et al. "Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions." International journal for parasitology. Drugs and drug resistance vol. 4,3 (2014): 164-84. doi: https://doi.org/10.1016/j.ijpddr.2014.07.007
Kotze AC, Hunt PW, Skuce P, von Samson-Himmelstjerna G, Martin RJ, Sager H, Krücken J, Hodgkinson J, Lespine A, Jex AR, Gilleard JS, Beech RN, Wolstenholme AJ, Demeler J, Robertson AP, Charvet CL, Neveu C, Kaminsky R, Rufener L, Alberich M, Menez C, Prichard RK. Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions. Int J Parasitol Drugs Drug Resist. 2014 Aug 13;4(3):164-84. doi: 10.1016/j.ijpddr.2014.07.007. eCollection 2014 Dec. PMID: 25516826; PMCID: PMC4266812.
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Nanotechnology-based drug delivery systems.

Journal of occupational medicine and toxicology (London, England)

Suri SS, Fenniri H, Singh B.
PMID: 18053152
J Occup Med Toxicol. 2007 Dec 01;2:16. doi: 10.1186/1745-6673-2-16.

Nanoparticles hold tremendous potential as an effective drug delivery system. In this review we discussed recent developments in nanotechnology for drug delivery. To overcome the problems of gene and drug delivery, nanotechnology has gained interest in recent years. Nanosystems...

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Suri SS, Fenniri H, Singh B. Nanotechnology-based drug delivery systems. J Occup Med Toxicol. 2007;2:16doi: 10.1186/1745-6673-2-16.
Suri, S. S., Fenniri, H., & Singh, B. (2007). Nanotechnology-based drug delivery systems. Journal of occupational medicine and toxicology (London, England), 216. https://doi.org/10.1186/1745-6673-2-16
Suri, Sarabjeet Singh, et al. "Nanotechnology-based drug delivery systems." Journal of occupational medicine and toxicology (London, England) vol. 2 (2007): 16. doi: https://doi.org/10.1186/1745-6673-2-16
Suri SS, Fenniri H, Singh B. Nanotechnology-based drug delivery systems. J Occup Med Toxicol. 2007 Dec 01;2:16. doi: 10.1186/1745-6673-2-16. PMID: 18053152; PMCID: PMC2222591.
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Retroviruses and opportunistic infections--eighth annual conference--structured therapy interruption.

IDrugs : the investigational drugs journal

Poli G, Vicenzi E.
PMID: 16012888
IDrugs. 2001 May;4(5):518-21.

The Eighth Conference on Retroviruses and Opportunistic Infections (CROI) marked a moment of great uncertainty among physicians on how to manage antiretrovirals in the long term. Several protocols of structured therapy interruption (STI) suggest that a better, less toxic...

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Poli G, Vicenzi E. Retroviruses and opportunistic infections--eighth annual conference--structured therapy interruption. IDrugs. 2001;4(5):518-21
Poli, G., & Vicenzi, E. (2001). Retroviruses and opportunistic infections--eighth annual conference--structured therapy interruption. IDrugs : the investigational drugs journal, 4(5), 518-21.
Poli, G, and Vicenzi, E. "Retroviruses and opportunistic infections--eighth annual conference--structured therapy interruption." IDrugs : the investigational drugs journal vol. 4,5 (2001): 518-21.
Poli G, Vicenzi E. Retroviruses and opportunistic infections--eighth annual conference--structured therapy interruption. IDrugs. 2001 May;4(5):518-21. PMID: 16012888.
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In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics.

Drug metabolism and disposition: the biological fate of chemicals

Takayama K, Ito K, Matsui A, Yamashita T, Kawakami K, Hirayama D, Kishimoto W, Nakase H, Mizuguchi H.
PMID: 33384384
Drug Metab Dispos. 2021 Mar;49(3):221-232. doi: 10.1124/dmd.120.000283. Epub 2020 Dec 31.

Orally administered drugs are absorbed and metabolized in the intestine. To accurately predict pharmacokinetics in the intestine, it is essential to understand the intestinal expression profiles of the genes related to drug absorption, distribution, metabolism, and excretion (ADME). However,...

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Takayama K, Ito K, Matsui A, et al. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics. Drug Metab Dispos. 2020;49(3):221-232doi: 10.1124/dmd.120.000283.
Takayama, K., Ito, K., Matsui, A., Yamashita, T., Kawakami, K., Hirayama, D., Kishimoto, W., Nakase, H., & Mizuguchi, H. (2021). In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics. Drug metabolism and disposition: the biological fate of chemicals, 49(3), 221-232. https://doi.org/10.1124/dmd.120.000283
Takayama, Kazuo, et al. "In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics." Drug metabolism and disposition: the biological fate of chemicals vol. 49,3 (2021): 221-232. doi: https://doi.org/10.1124/dmd.120.000283
Takayama K, Ito K, Matsui A, Yamashita T, Kawakami K, Hirayama D, Kishimoto W, Nakase H, Mizuguchi H. In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics. Drug Metab Dispos. 2021 Mar;49(3):221-232. doi: 10.1124/dmd.120.000283. Epub 2020 Dec 31. PMID: 33384384.
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Showing 1 to 7 of 7 entries