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Synthesis of chiral cyclic amines via Ir-catalyzed enantioselective hydrogenation of cyclic imines.

Organic & biomolecular chemistry

Zhang Y, Kong D, Wang R, Hou G.
PMID: 28294268
Org Biomol Chem. 2017 Apr 05;15(14):3006-3012. doi: 10.1039/c7ob00442g.

A highly enantioselective hydrogenation of cyclic imines for synthesis of chiral cyclic amines has been realized. With the complex of iridium and (R,R)-f-spiroPhos as the catalyst, a range of cyclic 2-aryl imines were smoothly hydrogenated under mild conditions without...

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Zhang Y, Kong D, Wang R, et al. Synthesis of chiral cyclic amines via Ir-catalyzed enantioselective hydrogenation of cyclic imines. Org Biomol Chem. 2017;15(14):3006-3012doi: 10.1039/c7ob00442g.
Zhang, Y., Kong, D., Wang, R., & Hou, G. (2017). Synthesis of chiral cyclic amines via Ir-catalyzed enantioselective hydrogenation of cyclic imines. Organic & biomolecular chemistry, 15(14), 3006-3012. https://doi.org/10.1039/c7ob00442g
Zhang, Ying, et al. "Synthesis of chiral cyclic amines via Ir-catalyzed enantioselective hydrogenation of cyclic imines." Organic & biomolecular chemistry vol. 15,14 (2017): 3006-3012. doi: https://doi.org/10.1039/c7ob00442g
Zhang Y, Kong D, Wang R, Hou G. Synthesis of chiral cyclic amines via Ir-catalyzed enantioselective hydrogenation of cyclic imines. Org Biomol Chem. 2017 Apr 05;15(14):3006-3012. doi: 10.1039/c7ob00442g. PMID: 28294268.
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Radioactive ion beams of .

The Review of scientific instruments

Naik V, Bhattacharjee M, Kumar DL, Karmakar P, Das SK, Banerjee D, Chattopadhyay S, Barua L, Das SS, Pal AK, Bandyopadhyay A, Chakrabarti A.
PMID: 28667954
Rev Sci Instrum. 2017 Jun;88(6):063308. doi: 10.1063/1.4985638.

Radioactive ion beams of

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Naik V, Bhattacharjee M, Kumar DL, et al. Radioactive ion beams of . Rev Sci Instrum. 2017;88(6):063308doi: 10.1063/1.4985638.
Naik, V., Bhattacharjee, M., Kumar, D. L., Karmakar, P., Das, S. K., Banerjee, D., Chattopadhyay, S., Barua, L., Das, S. S., Pal, A. K., Bandyopadhyay, A., & Chakrabarti, A. (2017). Radioactive ion beams of . The Review of scientific instruments, 88(6), 063308. https://doi.org/10.1063/1.4985638
Naik, Vaishali, et al. "Radioactive ion beams of ." The Review of scientific instruments vol. 88,6 (2017): 063308. doi: https://doi.org/10.1063/1.4985638
Naik V, Bhattacharjee M, Kumar DL, Karmakar P, Das SK, Banerjee D, Chattopadhyay S, Barua L, Das SS, Pal AK, Bandyopadhyay A, Chakrabarti A. Radioactive ion beams of . Rev Sci Instrum. 2017 Jun;88(6):063308. doi: 10.1063/1.4985638. PMID: 28667954.
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Radiopharmaceuticals for Therapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Le D.
PMID: 28546335
J Nucl Med. 2017 May 25; doi: 10.2967/jnumed.117.196568. Epub 2017 May 25.

No abstract available.

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Le D. Radiopharmaceuticals for Therapy. J Nucl Med. 2017;doi: 10.2967/jnumed.117.196568.
Le, D. (2017). Radiopharmaceuticals for Therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, . https://doi.org/10.2967/jnumed.117.196568
Le, Dao. "Radiopharmaceuticals for Therapy." Journal of nuclear medicine : official publication, Society of Nuclear Medicine vol. (2017). doi: https://doi.org/10.2967/jnumed.117.196568
Le D. Radiopharmaceuticals for Therapy. J Nucl Med. 2017 May 25; doi: 10.2967/jnumed.117.196568. Epub 2017 May 25. PMID: 28546335.
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F-18 Labeled RGD Probes Based on Bioorthogonal Strain-Promoted Click Reaction for PET Imaging.

ACS medicinal chemistry letters

Kim HL, Sachin K, Jeong HJ, Choi W, Lee HS, Kim DW.
PMID: 25893040
ACS Med Chem Lett. 2015 Feb 06;6(4):402-7. doi: 10.1021/ml500464f. eCollection 2015 Apr 09.

A series of fluorine-substituted monomeric and dimeric cRGD peptide derivatives, such as cRGD-ADIBOT-F (ADIBOT = azadibenzocyclooctatriazole), di-cRGD-ADIBOT-F, cRGD-PEG5-ADIBOT-F, and di-cRGD-PEG5-ADIBOT-F, were prepared by strain-promoted alkyne azide cycloaddition (SPAAC) reaction of the corresponding aza-dibenzocyclooctyne (ADIBO) substituted peptides with a fluorinated...

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Kim HL, Sachin K, Jeong HJ, et al. F-18 Labeled RGD Probes Based on Bioorthogonal Strain-Promoted Click Reaction for PET Imaging. ACS Med Chem Lett. 2015;6(4):402-7doi: 10.1021/ml500464f.
Kim, H. L., Sachin, K., Jeong, H. J., Choi, W., Lee, H. S., & Kim, D. W. (2015). F-18 Labeled RGD Probes Based on Bioorthogonal Strain-Promoted Click Reaction for PET Imaging. ACS medicinal chemistry letters, 6(4), 402-7. https://doi.org/10.1021/ml500464f
Kim, Hye Lan, et al. "F-18 Labeled RGD Probes Based on Bioorthogonal Strain-Promoted Click Reaction for PET Imaging." ACS medicinal chemistry letters vol. 6,4 (2015): 402-7. doi: https://doi.org/10.1021/ml500464f
Kim HL, Sachin K, Jeong HJ, Choi W, Lee HS, Kim DW. F-18 Labeled RGD Probes Based on Bioorthogonal Strain-Promoted Click Reaction for PET Imaging. ACS Med Chem Lett. 2015 Feb 06;6(4):402-7. doi: 10.1021/ml500464f. eCollection 2015 Apr 09. PMID: 25893040; PMCID: PMC4394342.
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Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer.

American journal of nuclear medicine and molecular imaging

Bouvet V, Jans HS, Wuest M, Soueidan OM, Mercer J, McEwan AJ, West FG, Cheeseman CI, Wuest F.
PMID: 24795839
Am J Nucl Med Mol Imaging. 2014 Apr 25;4(3):248-59. eCollection 2014.

6-Deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF) is a promising PET radiotracer for imaging GLUT5 in breast cancer. The present work describes GMP synthesis of 6-[(18)F]FDF in an automated synthesis unit (ASU) and dosimetry calculations to determine radiation doses in humans. GMP synthesis and...

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Bouvet V, Jans HS, Wuest M, et al. Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer. Am J Nucl Med Mol Imaging. 2014;4(3):248-59
Bouvet, V., Jans, H. S., Wuest, M., Soueidan, O. M., Mercer, J., McEwan, A. J., West, F. G., Cheeseman, C. I., & Wuest, F. (2014). Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer. American journal of nuclear medicine and molecular imaging, 4(3), 248-59.
Bouvet, Vincent, et al. "Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer." American journal of nuclear medicine and molecular imaging vol. 4,3 (2014): 248-59.
Bouvet V, Jans HS, Wuest M, Soueidan OM, Mercer J, McEwan AJ, West FG, Cheeseman CI, Wuest F. Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer. Am J Nucl Med Mol Imaging. 2014 Apr 25;4(3):248-59. eCollection 2014. PMID: 24795839; PMCID: PMC3999405.
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PET brain kinetics studies of (11)C-ITMM and (11)C-ITDM,radioprobes for metabotropic glutamate receptor type 1, in a nonhuman primate.

American journal of nuclear medicine and molecular imaging

Yamasaki T, Maeda J, Fujinaga M, Nagai Y, Hatori A, Yui J, Xie L, Nengaki N, Zhang MR.
PMID: 24795840
Am J Nucl Med Mol Imaging. 2014 Apr 25;4(3):260-9. eCollection 2014.

The metabotropic glutamate receptor type 1 (mGluR1) is a novel target protein for the development of new drugs against central nervous system disorders. Recently, we have developed (11)C-labeled PET probes (11)C-ITMM and (11)C-ITDM, which demonstrate similar profiles, for imaging...

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Yamasaki T, Maeda J, Fujinaga M, et al. PET brain kinetics studies of (11)C-ITMM and (11)C-ITDM,radioprobes for metabotropic glutamate receptor type 1, in a nonhuman primate. Am J Nucl Med Mol Imaging. 2014;4(3):260-9
Yamasaki, T., Maeda, J., Fujinaga, M., Nagai, Y., Hatori, A., Yui, J., Xie, L., Nengaki, N., & Zhang, M. R. (2014). PET brain kinetics studies of (11)C-ITMM and (11)C-ITDM,radioprobes for metabotropic glutamate receptor type 1, in a nonhuman primate. American journal of nuclear medicine and molecular imaging, 4(3), 260-9.
Yamasaki, Tomoteru, et al. "PET brain kinetics studies of (11)C-ITMM and (11)C-ITDM,radioprobes for metabotropic glutamate receptor type 1, in a nonhuman primate." American journal of nuclear medicine and molecular imaging vol. 4,3 (2014): 260-9.
Yamasaki T, Maeda J, Fujinaga M, Nagai Y, Hatori A, Yui J, Xie L, Nengaki N, Zhang MR. PET brain kinetics studies of (11)C-ITMM and (11)C-ITDM,radioprobes for metabotropic glutamate receptor type 1, in a nonhuman primate. Am J Nucl Med Mol Imaging. 2014 Apr 25;4(3):260-9. eCollection 2014. PMID: 24795840; PMCID: PMC3999406.
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Agonist signalling properties of radiotracers used for imaging of dopamine D2/3 receptors.

EJNMMI research

van Wieringen JP, Michel MC, Janssen HM, Janssen AG, Elsinga PH, Booij J.
PMID: 25977878
EJNMMI Res. 2014 Oct 07;4:53. doi: 10.1186/s13550-014-0053-3. eCollection 2014.

BACKGROUND: Dopamine D2/3 receptor (D2/3R) agonist radiopharmaceuticals are considered superior to antagonists to detect dopamine release, e.g. induced by amphetamines. Agonists bind preferentially to the high-affinity state of the dopamine D2R, which has been proposed as the reason why...

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van Wieringen JP, Michel MC, Janssen HM, et al. Agonist signalling properties of radiotracers used for imaging of dopamine D2/3 receptors. EJNMMI Res. 2014;4:53doi: 10.1186/s13550-014-0053-3.
van Wieringen, J. P., Michel, M. C., Janssen, H. M., Janssen, A. G., Elsinga, P. H., & Booij, J. (2014). Agonist signalling properties of radiotracers used for imaging of dopamine D2/3 receptors. EJNMMI research, 453. https://doi.org/10.1186/s13550-014-0053-3
van Wieringen, Jan-Peter, et al. "Agonist signalling properties of radiotracers used for imaging of dopamine D2/3 receptors." EJNMMI research vol. 4 (2014): 53. doi: https://doi.org/10.1186/s13550-014-0053-3
van Wieringen JP, Michel MC, Janssen HM, Janssen AG, Elsinga PH, Booij J. Agonist signalling properties of radiotracers used for imaging of dopamine D2/3 receptors. EJNMMI Res. 2014 Oct 07;4:53. doi: 10.1186/s13550-014-0053-3. eCollection 2014. PMID: 25977878; PMCID: PMC4422956.
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Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity.

ChemistryOpen

Strand J, Nordeman P, Honarvar H, Altai M, Orlova A, Larhed M, Tolmachev V.
PMID: 25969816
ChemistryOpen. 2015 Apr;4(2):174-82. doi: 10.1002/open.201402097. Epub 2015 Jan 12.

Affibody molecules are small scaffold-based affinity proteins with promising properties as probes for radionuclide-based molecular imaging. However, a high reabsorption of radiolabeled Affibody molecules in kidneys is an issue. We have shown that the use of (125)I-3-iodo-((4-hydroxyphenyl)ethyl)maleimide (IHPEM) for...

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Strand J, Nordeman P, Honarvar H, et al. Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity. ChemistryOpen. 2015;4(2):174-82doi: 10.1002/open.201402097.
Strand, J., Nordeman, P., Honarvar, H., Altai, M., Orlova, A., Larhed, M., & Tolmachev, V. (2015). Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity. ChemistryOpen, 4(2), 174-82. https://doi.org/10.1002/open.201402097
Strand, Joanna, et al. "Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity." ChemistryOpen vol. 4,2 (2015): 174-82. doi: https://doi.org/10.1002/open.201402097
Strand J, Nordeman P, Honarvar H, Altai M, Orlova A, Larhed M, Tolmachev V. Site-Specific Radioiodination of HER2-Targeting Affibody Molecules using 4-Iodophenethylmaleimide Decreases Renal Uptake of Radioactivity. ChemistryOpen. 2015 Apr;4(2):174-82. doi: 10.1002/open.201402097. Epub 2015 Jan 12. PMID: 25969816; PMCID: PMC4420590.
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Painful boney metastases.

Annals of palliative medicine

Smith HS.
PMID: 25841427
Ann Palliat Med. 2012 Apr;1(1):14-31. doi: 10.3978/j.issn.2224-5820.2012.02.03.

Treatments for painful osseous metastases may not only diminish pain, but also may improve quality of life and independence/mobility, and reduce skeletal morbidity, potential pathologic fractures, spinal cord compression, and other "skeletal-related events". Treatment strategies for painful osseous metastases...

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Smith HS. Painful boney metastases. Ann Palliat Med. 2012;1(1):14-31doi: 10.3978/j.issn.2224-5820.2012.02.03.
Smith, H. S. (2012). Painful boney metastases. Annals of palliative medicine, 1(1), 14-31. https://doi.org/10.3978/j.issn.2224-5820.2012.02.03
Smith, Howard S. "Painful boney metastases." Annals of palliative medicine vol. 1,1 (2012): 14-31. doi: https://doi.org/10.3978/j.issn.2224-5820.2012.02.03
Smith HS. Painful boney metastases. Ann Palliat Med. 2012 Apr;1(1):14-31. doi: 10.3978/j.issn.2224-5820.2012.02.03. PMID: 25841427.
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Characterization of SnO2-based (68)Ge/ (68)Ga generators and (68)Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy.

EJNMMI research

Sudbrock F, Fischer T, Zimmermanns B, Guliyev M, Dietlein M, Drzezga A, Schomäcker K.
PMID: 26055937
EJNMMI Res. 2014 Dec;4(1):36. doi: 10.1186/s13550-014-0036-4. Epub 2014 Jul 24.

BACKGROUND: With the increasing utilization of (68)Ge-(68)Ga radionuclide generators, (68)Ga labelled peptides like DOTATATE are receiving more attention in nuclear medicine. On the one hand, the long half-life of the parent nuclide (68)Ge is an enormous advantage for routine...

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Sudbrock F, Fischer T, Zimmermanns B, et al. Characterization of SnO2-based (68)Ge/ (68)Ga generators and (68)Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy. EJNMMI Res. 2014;4(1):36doi: 10.1186/s13550-014-0036-4.
Sudbrock, F., Fischer, T., Zimmermanns, B., Guliyev, M., Dietlein, M., Drzezga, A., & Schomäcker, K. (2014). Characterization of SnO2-based (68)Ge/ (68)Ga generators and (68)Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy. EJNMMI research, 4(1), 36. https://doi.org/10.1186/s13550-014-0036-4
Sudbrock, Ferdinand, et al. "Characterization of SnO2-based (68)Ge/ (68)Ga generators and (68)Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy." EJNMMI research vol. 4,1 (2014): 36. doi: https://doi.org/10.1186/s13550-014-0036-4
Sudbrock F, Fischer T, Zimmermanns B, Guliyev M, Dietlein M, Drzezga A, Schomäcker K. Characterization of SnO2-based (68)Ge/ (68)Ga generators and (68)Ga-DOTATATE preparations: radionuclide purity, radiochemical yield and long-term constancy. EJNMMI Res. 2014 Dec;4(1):36. doi: 10.1186/s13550-014-0036-4. Epub 2014 Jul 24. PMID: 26055937; PMCID: PMC4884004.
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Revolutionizing Alzheimer's disease and clinical trials through biomarkers.

Alzheimer's & dementia (Amsterdam, Netherlands)

Mattsson N, Carrillo MC, Dean RA, Devous MD, Nikolcheva T, Pesini P, Salter H, Potter WZ, Sperling RS, Bateman RJ, Bain LJ, Liu E.
PMID: 27239522
Alzheimers Dement (Amst). 2015 Oct 03;1(4):412-9. doi: 10.1016/j.dadm.2015.09.001. eCollection 2015 Dec.

The Alzheimer's Association's Research Roundtable met in May 2014 to explore recent progress in developing biomarkers to improve understanding of disease pathogenesis and expedite drug development. Although existing biomarkers have proved extremely useful for enrichment of subjects in clinical...

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Mattsson N, Carrillo MC, Dean RA, et al. Revolutionizing Alzheimer's disease and clinical trials through biomarkers. Alzheimers Dement (Amst). 2015;1(4):412-9doi: 10.1016/j.dadm.2015.09.001.
Mattsson, N., Carrillo, M. C., Dean, R. A., Devous, M. D., Nikolcheva, T., Pesini, P., Salter, H., Potter, W. Z., Sperling, R. S., Bateman, R. J., Bain, L. J., & Liu, E. (2015). Revolutionizing Alzheimer's disease and clinical trials through biomarkers. Alzheimer's & dementia (Amsterdam, Netherlands), 1(4), 412-9. https://doi.org/10.1016/j.dadm.2015.09.001
Mattsson, Niklas, et al. "Revolutionizing Alzheimer's disease and clinical trials through biomarkers." Alzheimer's & dementia (Amsterdam, Netherlands) vol. 1,4 (2015): 412-9. doi: https://doi.org/10.1016/j.dadm.2015.09.001
Mattsson N, Carrillo MC, Dean RA, Devous MD, Nikolcheva T, Pesini P, Salter H, Potter WZ, Sperling RS, Bateman RJ, Bain LJ, Liu E. Revolutionizing Alzheimer's disease and clinical trials through biomarkers. Alzheimers Dement (Amst). 2015 Oct 03;1(4):412-9. doi: 10.1016/j.dadm.2015.09.001. eCollection 2015 Dec. PMID: 27239522; PMCID: PMC4879481.
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Quality control of positron emission tomography radiopharmaceuticals: An institutional experience.

Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India

Shukla J, Vatsa R, Garg N, Bhusari P, Watts A, Mittal BR.
PMID: 24379528
Indian J Nucl Med. 2013 Oct;28(4):200-6. doi: 10.4103/0972-3919.121963.

PURPOSE OF THE STUDY: To study quality control parameters of routinely prepared positron emission tomography (PET) radiopharmaceuticals.MATERIALS AND METHODS: Three PET radiopharmaceuticals fluorine-18 fluorodeoxyglucose (F-18 FDG), N-13 ammonia (N-13 NH3), and Ga-68 DOTATATE (n = 25 each), prepared by...

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Shukla J, Vatsa R, Garg N, et al. Quality control of positron emission tomography radiopharmaceuticals: An institutional experience. Indian J Nucl Med. 2013;28(4):200-6doi: 10.4103/0972-3919.121963.
Shukla, J., Vatsa, R., Garg, N., Bhusari, P., Watts, A., & Mittal, B. R. (2013). Quality control of positron emission tomography radiopharmaceuticals: An institutional experience. Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India, 28(4), 200-6. https://doi.org/10.4103/0972-3919.121963
Shukla, Jaya, et al. "Quality control of positron emission tomography radiopharmaceuticals: An institutional experience." Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India vol. 28,4 (2013): 200-6. doi: https://doi.org/10.4103/0972-3919.121963
Shukla J, Vatsa R, Garg N, Bhusari P, Watts A, Mittal BR. Quality control of positron emission tomography radiopharmaceuticals: An institutional experience. Indian J Nucl Med. 2013 Oct;28(4):200-6. doi: 10.4103/0972-3919.121963. PMID: 24379528; PMCID: PMC3866663.
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Showing 1 to 12 of 1429 entries