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Advances in Analytical Technologies for Extracellular Vesicles.

Analytical chemistry

Yan H, Li Y, Cheng S, Zeng Y.
PMID: 33635060
Anal Chem. 2021 Mar 23;93(11):4739-4774. doi: 10.1021/acs.analchem.1c00693. Epub 2021 Feb 26.

No abstract available.

Microfluidic Exponential Rolling Circle Amplification for Sensitive microRNA Detection Directly from Biological Samples.

Sensors and actuators. B, Chemical

Cao H, Zhou X, Zeng Y.
PMID: 30533973
Sens Actuators B Chem. 2019 Jan 15;279:447-457. doi: 10.1016/j.snb.2018.09.121. Epub 2018 Oct 04.

There is an urgent need of sensitive bioanalytical platforms for sensitive and precise quantification of low-abundance microRNA targets in complex biological samples, including liquid biopsies of tumors. Many of current miRNA biosensing methods require laborious sample pretreatment procedures, including...

Ewing sarcoma family of tumors-derived small extracellular vesicle proteomics identify potential clinical biomarkers.

Oncotarget

Samuel G, Crow J, Klein JB, Merchant ML, Nissen E, Koestler DC, Laurence K, Liang X, Neville K, Staggs V, Ahmed A, Atay S, Godwin AK.
PMID: 32821345
Oncotarget. 2020 Aug 04;11(31):2995-3012. doi: 10.18632/oncotarget.27678. eCollection 2020 Aug 04.

PURPOSE: Ewing Sarcoma Family of Tumors (ESFT), the second most common pediatric osseous malignancy, are characterized by the pathognomonic chromosomal MATERIALS AND METHODS: We performed the first high quality proteomic study of ESFT-derived sEVs from 5 ESFT cell lines...

Advances in microfluidic extracellular vesicle analysis for cancer diagnostics.

Lab on a chip

Cheng S, Li Y, Yan H, Wen Y, Zhou X, Friedman L, Zeng Y.
PMID: 34352059
Lab Chip. 2021 Sep 07;21(17):3219-3243. doi: 10.1039/d1lc00443c. Epub 2021 Aug 05.

Extracellular vesicles (EVs) secreted by cells into the bloodstream and other bodily fluids, including exosomes, have been demonstrated to be a class of significant messengers that mediate intercellular communications. Tumor-derived extracellular vesicles are enriched in a selective set of...

Showing 1 to 4 of 4 entries