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Advances in Analytical Technologies for Extracellular Vesicles.

Analytical chemistry

Yan H, Li Y, Cheng S, Zeng Y.
PMID: 33635060
Anal Chem. 2021 Mar 23;93(11):4739-4774. doi: 10.1021/acs.analchem.1c00693. Epub 2021 Feb 26.

No abstract available.

Microfluidic platform for selective microparticle parking and paired particle isolation in droplet arrays.

Biomicrofluidics

Chen L, Kim JJ, Doyle PS.
PMID: 29576834
Biomicrofluidics. 2018 Mar 01;12(2):024102. doi: 10.1063/1.5011342. eCollection 2018 Mar.

Immobilizing microscale objects (e.g., cells, spheroids, and microparticles) in arrays for direct observation and analysis is a critical step of many biological and chemical assays; however, existing techniques are often limited in their ability to precisely capture, arrange, isolate,...

Spatially resolved and multiplexed MicroRNA quantification from tissue using nanoliter well arrays.

Microsystems & nanoengineering

Nagarajan MB, Tentori AM, Zhang WC, Slack FJ, Doyle PS.
PMID: 32419951
Microsyst Nanoeng. 2020 May 09;6:51. doi: 10.1038/s41378-020-0169-8. eCollection 2020.

Spatially resolved gene expression patterns are emerging as a key component of medical studies, including companion diagnostics, but technologies for quantification and multiplexing are limited. We present a method to perform spatially resolved and multiplexed microRNA (miRNA) measurements from...

Microfluidic Exponential Rolling Circle Amplification for Sensitive microRNA Detection Directly from Biological Samples.

Sensors and actuators. B, Chemical

Cao H, Zhou X, Zeng Y.
PMID: 30533973
Sens Actuators B Chem. 2019 Jan 15;279:447-457. doi: 10.1016/j.snb.2018.09.121. Epub 2018 Oct 04.

There is an urgent need of sensitive bioanalytical platforms for sensitive and precise quantification of low-abundance microRNA targets in complex biological samples, including liquid biopsies of tumors. Many of current miRNA biosensing methods require laborious sample pretreatment procedures, including...

Showing 1 to 4 of 4 entries