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Showing 1 to 12 of 61 entries
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Selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells.

Chinese journal of cancer research = Chung-kuo yen cheng yen chiu

Shao J, Feng G.
PMID: 24385693
Chin J Cancer Res. 2013 Dec;25(6):662-70. doi: 10.3978/j.issn.1000-9604.2013.11.05.

OBJECTIVE: To determine the selective killing effect of oxytetracycline, propafenone and metamizole on A549 or Hela cells.METHODS: Proliferation assay, lactate dehydrogenase (LDH) assay, apoptosis detecting, flow cytometry and western blot were performed.RESULTS: It was found that treatment with propafenone...

Risk of Cardiovascular Events, Stroke, Congestive Heart Failure, Interstitial Lung Disease, and Acute Liver Injury: Dronedarone versus Amiodarone and Other Antiarrhythmics.

Journal of atrial fibrillation

Gao S, Dai W, Zhang L, Juhaeri J, Wang Y, Caubel P.
PMID: 28496906
J Atr Fibrillation. 2013 Dec 31;6(4):890. doi: 10.4022/jafib.890. eCollection 2013 Dec.

No published studies have evaluated the risks of cardiovascular (CV) events, stroke, congestive heart failure (CHF), interstitial lung disease (ILD), and severe acute liver injury (ALI) related to antiarrhythmics treatment in real-world clinical practice setting. We examined the relationship...

Electrophysiologic and Antiarrhythmic Effects of Propafenone: Focus on Atrial Fibrillation.

Journal of cardiovascular pharmacology and therapeutics

Valderrábano M, Singh BN.
PMID: 10684540
J Cardiovasc Pharmacol Ther. 1999 Jul;4(3):183-198. doi: 10.1177/107424849900400308.

No abstract available.

Functional and metabolic effects of propafenone in the rat heart-lung preparation.

Journal of anesthesia

Kashimoto S, Oguchi T, Nakamura T, Kumazawa T.
PMID: 15278609
J Anesth. 1991 Oct;5(4):392-5. doi: 10.1007/s0054010050392.

The effects of propafenone on cardiac function and myocardial metabolism were assessed in the isolated rat heart-lung preparation. Propafenone 0.3, 3 or 30 microg.ml(-1) was administered 5 min after the start of perfusion. Heart rate decreased in the 30...

Propafenone is not effective for severe ventricular arrhythmias in Andersen-Tawil syndrome.

Archives of medical science : AMS

Bienias P, Kostera-Pruszczyk A, Miszczak-Knecht M, Ciurzyński M, Pruszczyk P.
PMID: 29379555
Arch Med Sci. 2018 Jan;14(1):248-250. doi: 10.5114/aoms.2016.61010. Epub 2016 Jun 30.

No abstract available.

Inhibition of voltage-dependent K.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

An JR, Li H, Seo MS, Park WS.
PMID: 30181706
Korean J Physiol Pharmacol. 2018 Sep;22(5):597-605. doi: 10.4196/kjpp.2018.22.5.597. Epub 2018 Aug 27.

In this study, we demonstrated the inhibitory effect of the Class Ic antiarrhythmic agent propafenone on voltage-dependent K

Pharmacokinetics of propafenone hydrochloride sustained-release capsules in male beagle dogs.

Acta pharmaceutica Sinica. B

Pan L, Qian Y, Cheng M, Gu P, He Y, Xu X, Ding L.
PMID: 26579428
Acta Pharm Sin B. 2015 Jan;5(1):74-8. doi: 10.1016/j.apsb.2014.11.003. Epub 2015 Jan 07.

This paper describes the development and validation of a liquid chromatography-mass spectrometric assay for propafenone and its application to a pharmacokinetic study of propafenone administered as a new propafenone hydrochloride sustained-release capsule (SR-test), as an instant-release tablet (IR-reference) and...

Cardiac function evaluation for a novel one-step detoxification product of .

Chinese medicine

He YN, Zhang DK, Lin JZ, Han X, Zhang YM, Zhang HZ, Pei J, Yang M, Wang JB.
PMID: 30568725
Chin Med. 2018 Dec 17;13:62. doi: 10.1186/s13020-018-0219-4. eCollection 2018.

METHODS: Initially, network pharmacology was applied to analyze the related pathways of candidate components acting on heart failure diseases. Then, two heart failure models that were induced by propafenone hydrochloride and nimodipine (v/v, 1:1) and were given doxorubicin were...

Propafenone Poisoning of a Female Adolescent After a Suicide Attempt.

Cureus

Keramari S, Poutoglidis A, Poutoglidou F, Kaiafa G, Keramaris M.
PMID: 34434676
Cureus. 2021 Jul 23;13(7):e16576. doi: 10.7759/cureus.16576. eCollection 2021 Jul.

Propafenone is an antiarrhythmic agent for the management of ventricular and supraventricular tachycardia and atrial fibrillation. Propafenone poisoning is rare but may be life-threatening due to drug-induced arrhythmias. Electrocardiographic changes in PR, QRS, and QT intervals have been recorded....

Formulation and stability of an extemporaneously compounded propafenone hydrochloride oral suspension for children with arrhythmia.

European journal of hospital pharmacy : science and practice

Lin YS, Lin SC, Hsieh YT, Liu LY, Lin CH, Shen LJ, Huang CF.
PMID: 33608396
Eur J Hosp Pharm. 2021 Feb 19; doi: 10.1136/ejhpharm-2020-002567. Epub 2021 Feb 19.

OBJECTIVES: In children, supraventricular tachycardia is the most common form of arrhythmia, and propafenone is an effective class Ic antiarrhythmic agent used in this population. No suitable paediatric-specific, dosing-flexible preparation is available in Taiwan. The objective of this study...

Cardiac Arrest Following Treatment With Diltiazem for Atrial Fibrillation With Rapid Ventricular Response.

Cureus

Lee WK, Shameem M, Ganti L, Banerjee PR, Shivdat J.
PMID: 33391915
Cureus. 2020 Nov 24;12(11):e11678. doi: 10.7759/cureus.11678.

We present the case of a 43-year-old man with a history of atrial fibrillation and poor medical compliance who presented to the emergency department with palpitations for three hours. Electrocardiogram (ECG) revealed atrial fibrillation with rapid ventricular response at...

Propafenone-Induced QRS Widening in a Child With Arrhythmogenic Right Ventricular Cardiomyopathy: A Case Report and Literatures Review.

Frontiers in pediatrics

Chu YQ, Wang C, Li XM, Wang H.
PMID: 33194879
Front Pediatr. 2020 Oct 30;8:481330. doi: 10.3389/fped.2020.481330. eCollection 2020.

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare cardiac disease in children, and can lead to sudden cardiac death (SCD). Propafenone is classI

Showing 1 to 12 of 61 entries