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The European LEMS Registry: Baseline Demographics and Treatment Approaches.

Neurology and therapy

Mantegazza R, Meisel A, Sieb JP, Le Masson G, Desnuelle C, Essing M.
PMID: 26525537
Neurol Ther. 2015 Dec;4(2):105-24. doi: 10.1007/s40120-015-0034-0. Epub 2015 Nov 02.

INTRODUCTION: Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder affecting the neuromuscular junction, clinically characterized by proximal muscle weakness and autonomic changes. LEMS is often associated with an underlying tumor (paraneoplastic form) but also occurs in the absence...

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Mantegazza R, Meisel A, Sieb JP, et al. The European LEMS Registry: Baseline Demographics and Treatment Approaches. Neurol Ther. 2015;4(2):105-24doi: 10.1007/s40120-015-0034-0.
Mantegazza, R., Meisel, A., Sieb, J. P., Le Masson, G., Desnuelle, C., & Essing, M. (2015). The European LEMS Registry: Baseline Demographics and Treatment Approaches. Neurology and therapy, 4(2), 105-24. https://doi.org/10.1007/s40120-015-0034-0
Mantegazza, Renato, et al. "The European LEMS Registry: Baseline Demographics and Treatment Approaches." Neurology and therapy vol. 4,2 (2015): 105-24. doi: https://doi.org/10.1007/s40120-015-0034-0
Mantegazza R, Meisel A, Sieb JP, Le Masson G, Desnuelle C, Essing M. The European LEMS Registry: Baseline Demographics and Treatment Approaches. Neurol Ther. 2015 Dec;4(2):105-24. doi: 10.1007/s40120-015-0034-0. Epub 2015 Nov 02. PMID: 26525537; PMCID: PMC4685864.
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4-aminopyridine improves lower urinary tract symptoms in a patient with benign prostatic hyperplasia and downbeat nystagmus syndrome.

International neurourology journal

Strupp M, Feil K, Bardins S, Waidelich R.
PMID: 25558420
Int Neurourol J. 2014 Dec;18(4):221-5. doi: 10.5213/inj.2014.18.4.221. Epub 2014 Dec 29.

Aminopyridines are potassium channel blockers that increase the excitability of nerve cells and axons; therefore, they are widely used to treat different neurological disorders. Here we present a patient with idiopathic downbeat nystagmus and lower urinary tract symptoms (LUTS)...

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Strupp M, Feil K, Bardins S, et al. 4-aminopyridine improves lower urinary tract symptoms in a patient with benign prostatic hyperplasia and downbeat nystagmus syndrome. Int Neurourol J. 2014;18(4):221-5doi: 10.5213/inj.2014.18.4.221.
Strupp, M., Feil, K., Bardins, S., & Waidelich, R. (2014). 4-aminopyridine improves lower urinary tract symptoms in a patient with benign prostatic hyperplasia and downbeat nystagmus syndrome. International neurourology journal, 18(4), 221-5. https://doi.org/10.5213/inj.2014.18.4.221
Strupp, Michael, et al. "4-aminopyridine improves lower urinary tract symptoms in a patient with benign prostatic hyperplasia and downbeat nystagmus syndrome." International neurourology journal vol. 18,4 (2014): 221-5. doi: https://doi.org/10.5213/inj.2014.18.4.221
Strupp M, Feil K, Bardins S, Waidelich R. 4-aminopyridine improves lower urinary tract symptoms in a patient with benign prostatic hyperplasia and downbeat nystagmus syndrome. Int Neurourol J. 2014 Dec;18(4):221-5. doi: 10.5213/inj.2014.18.4.221. Epub 2014 Dec 29. PMID: 25558420; PMCID: PMC4280442.
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Pharmacology down under in 2000.

Drug news & perspectives

Doggrell SA.
PMID: 12879135
Drug News Perspect. 2000 Dec;13(10):634-40.

In December the pharmacologists and toxicologists of Australia and New Zealand get together for their annual scientific meeting, which is made up of pre-meeting workshops followed by invited lectures, symposia and free communications. This year, one of the pre-meeting...

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Doggrell SA. Pharmacology down under in 2000. Drug News Perspect. 2000;13(10):634-40
Doggrell, S. A. (2000). Pharmacology down under in 2000. Drug news & perspectives, 13(10), 634-40.
Doggrell, S A. "Pharmacology down under in 2000." Drug news & perspectives vol. 13,10 (2000): 634-40.
Doggrell SA. Pharmacology down under in 2000. Drug News Perspect. 2000 Dec;13(10):634-40. PMID: 12879135.
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The reduction of food intake induced in mice by benzylamine and its derivatives.

Inflammopharmacology

Raimondi L, Banchelli G, Ghelardini C, Pirisino R.
PMID: 15035821
Inflammopharmacology. 2003;11(2):189-94. doi: 10.1163/156856003765764362.

Characterisation of the pharmacological profile of non-physiological amine oxidase substrates could help to identify the endogenous role of this class of enzymes. Previous studies have suggested that benzylamine, a common non-physiological substrate for monoamine and tissue-bound or soluble benzylamine...

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Raimondi L, Banchelli G, Ghelardini C, et al. The reduction of food intake induced in mice by benzylamine and its derivatives. Inflammopharmacology. 2003;11(2):189-94doi: 10.1163/156856003765764362.
Raimondi, L., Banchelli, G., Ghelardini, C., & Pirisino, R. (2003). The reduction of food intake induced in mice by benzylamine and its derivatives. Inflammopharmacology, 11(2), 189-94. https://doi.org/10.1163/156856003765764362
Raimondi, L, et al. "The reduction of food intake induced in mice by benzylamine and its derivatives." Inflammopharmacology vol. 11,2 (2003): 189-94. doi: https://doi.org/10.1163/156856003765764362
Raimondi L, Banchelli G, Ghelardini C, Pirisino R. The reduction of food intake induced in mice by benzylamine and its derivatives. Inflammopharmacology. 2003;11(2):189-94. doi: 10.1163/156856003765764362. PMID: 15035821.
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How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation?.

Journal of atrial fibrillation

Burashnikov A, Antzelevitch C.
PMID: 21057583
J Atr Fibrillation. 2008;1(2):98-107. doi: 10.4022/jafib.v1i1.400.

Current pharmacologic strategies for the management of Atrial fibrillation (AF) include use of 1) sodium channel blockers, which are contraindicated in patients with coronary artery or structural heart disease because of their potent effect to slow conduction in the...

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Burashnikov A, Antzelevitch C. How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation?. J Atr Fibrillation. 2008;1(2):98-107doi: 10.4022/jafib.v1i1.400.
Burashnikov, A., & Antzelevitch, C. (2008). How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation?. Journal of atrial fibrillation, 1(2), 98-107. https://doi.org/10.4022/jafib.v1i1.400
Burashnikov, Alexander, and Antzelevitch, Charles. "How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation?." Journal of atrial fibrillation vol. 1,2 (2008): 98-107. doi: https://doi.org/10.4022/jafib.v1i1.400
Burashnikov A, Antzelevitch C. How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation?. J Atr Fibrillation. 2008;1(2):98-107. doi: 10.4022/jafib.v1i1.400. PMID: 21057583; PMCID: PMC2970929.
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The calcium-activated slow AHP: cutting through the Gordian knot.

Frontiers in cellular neuroscience

Andrade R, Foehring RC, Tzingounis AV.
PMID: 23112761
Front Cell Neurosci. 2012 Oct 25;6:47. doi: 10.3389/fncel.2012.00047. eCollection 2012.

The phenomenon known as the slow afterhyperpolarization (sAHP) was originally described more than 30 years ago in pyramidal cells as a slow, Ca(2+)-dependent afterpotential controlling spike frequency adaptation. Subsequent work showed that similar sAHPs were widely expressed in the...

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Andrade R, Foehring RC, Tzingounis AV. The calcium-activated slow AHP: cutting through the Gordian knot. Front Cell Neurosci. 2012;6:47doi: 10.3389/fncel.2012.00047.
Andrade, R., Foehring, R. C., & Tzingounis, A. V. (2012). The calcium-activated slow AHP: cutting through the Gordian knot. Frontiers in cellular neuroscience, 647. https://doi.org/10.3389/fncel.2012.00047
Andrade, Rodrigo, et al. "The calcium-activated slow AHP: cutting through the Gordian knot." Frontiers in cellular neuroscience vol. 6 (2012): 47. doi: https://doi.org/10.3389/fncel.2012.00047
Andrade R, Foehring RC, Tzingounis AV. The calcium-activated slow AHP: cutting through the Gordian knot. Front Cell Neurosci. 2012 Oct 25;6:47. doi: 10.3389/fncel.2012.00047. eCollection 2012. PMID: 23112761; PMCID: PMC3480710.
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Current treatment of vestibular, ocular motor disorders and nystagmus.

Therapeutic advances in neurological disorders

Strupp M, Brandt T.
PMID: 21179531
Ther Adv Neurol Disord. 2009 Jul;2(4):223-39. doi: 10.1177/1756285609103120.

Vertigo and dizziness are among the most common complaints with a lifetime prevalence of about 30%. The various forms of vestibular disorders can be treated with pharmacological therapy, physical therapy, psychotherapeutic measures or, rarely, surgery. In this review, the...

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Strupp M, Brandt T. Current treatment of vestibular, ocular motor disorders and nystagmus. Ther Adv Neurol Disord. 2009;2(4):223-39doi: 10.1177/1756285609103120.
Strupp, M., & Brandt, T. (2009). Current treatment of vestibular, ocular motor disorders and nystagmus. Therapeutic advances in neurological disorders, 2(4), 223-39. https://doi.org/10.1177/1756285609103120
Strupp, Michael, and Brandt, Thomas. "Current treatment of vestibular, ocular motor disorders and nystagmus." Therapeutic advances in neurological disorders vol. 2,4 (2009): 223-39. doi: https://doi.org/10.1177/1756285609103120
Strupp M, Brandt T. Current treatment of vestibular, ocular motor disorders and nystagmus. Ther Adv Neurol Disord. 2009 Jul;2(4):223-39. doi: 10.1177/1756285609103120. PMID: 21179531; PMCID: PMC3002631.
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The Clubroot Pathogen (Plasmodiophora brassicae) Influences Auxin Signaling to Regulate Auxin Homeostasis in Arabidopsis.

Plants (Basel, Switzerland)

Jahn L, Mucha S, Bergmann S, Horn C, Staswick P, Steffens B, Siemens J, Ludwig-Müller J.
PMID: 27137401
Plants (Basel). 2013 Nov 27;2(4):726-49. doi: 10.3390/plants2040726.

The clubroot disease, caused by the obligate biotrophic protist Plasmodiophora brassicae, affects cruciferous crops worldwide. It is characterized by root swellings as symptoms, which are dependent on the alteration of auxin and cytokinin metabolism. Here, we describe that two...

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Jahn L, Mucha S, Bergmann S, et al. The Clubroot Pathogen (Plasmodiophora brassicae) Influences Auxin Signaling to Regulate Auxin Homeostasis in Arabidopsis. Plants (Basel). 2013;2(4):726-49doi: 10.3390/plants2040726.
Jahn, L., Mucha, S., Bergmann, S., Horn, C., Staswick, P., Steffens, B., Siemens, J., & Ludwig-Müller, J. (2013). The Clubroot Pathogen (Plasmodiophora brassicae) Influences Auxin Signaling to Regulate Auxin Homeostasis in Arabidopsis. Plants (Basel, Switzerland), 2(4), 726-49. https://doi.org/10.3390/plants2040726
Jahn, Linda, et al. "The Clubroot Pathogen (Plasmodiophora brassicae) Influences Auxin Signaling to Regulate Auxin Homeostasis in Arabidopsis." Plants (Basel, Switzerland) vol. 2,4 (2013): 726-49. doi: https://doi.org/10.3390/plants2040726
Jahn L, Mucha S, Bergmann S, Horn C, Staswick P, Steffens B, Siemens J, Ludwig-Müller J. The Clubroot Pathogen (Plasmodiophora brassicae) Influences Auxin Signaling to Regulate Auxin Homeostasis in Arabidopsis. Plants (Basel). 2013 Nov 27;2(4):726-49. doi: 10.3390/plants2040726. PMID: 27137401; PMCID: PMC4844388.
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Voltage-gated potassium channels are critical for infrared inhibition of action potentials: an experimental study.

Neurophotonics

Ganguly M, Ford JB, Zhuo J, McPheeters MT, Jenkins MW, Chiel HJ, Jansen ED.
PMID: 31620544
Neurophotonics. 2019 Oct;6(4):040501. doi: 10.1117/1.NPh.6.4.040501. Epub 2019 Oct 15.

Thermal block of unmyelinated axons may serve as a modality for control, suggesting a means for providing therapies for pain. Computational modeling predicted that potassium channels are necessary for mediating thermal block of propagating compound action potentials (CAPs) with...

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Ganguly M, Ford JB, Zhuo J, et al. Voltage-gated potassium channels are critical for infrared inhibition of action potentials: an experimental study. Neurophotonics. 2019;6(4):040501doi: 10.1117/1.NPh.6.4.040501.
Ganguly, M., Ford, J. B., Zhuo, J., McPheeters, M. T., Jenkins, M. W., Chiel, H. J., & Jansen, E. D. (2019). Voltage-gated potassium channels are critical for infrared inhibition of action potentials: an experimental study. Neurophotonics, 6(4), 040501. https://doi.org/10.1117/1.NPh.6.4.040501
Ganguly, Mohit, et al. "Voltage-gated potassium channels are critical for infrared inhibition of action potentials: an experimental study." Neurophotonics vol. 6,4 (2019): 040501. doi: https://doi.org/10.1117/1.NPh.6.4.040501
Ganguly M, Ford JB, Zhuo J, McPheeters MT, Jenkins MW, Chiel HJ, Jansen ED. Voltage-gated potassium channels are critical for infrared inhibition of action potentials: an experimental study. Neurophotonics. 2019 Oct;6(4):040501. doi: 10.1117/1.NPh.6.4.040501. Epub 2019 Oct 15. PMID: 31620544; PMCID: PMC6792434.
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Azobenzene/Tetraethyl Ammonium Photochromic Potassium Channel Blockers: Scope and Limitations for Design of Para-Substituted Derivatives with Specific Absorption Band Maxima and Thermal Isomerization Rate.

International journal of molecular sciences

Strashkov DM, Mironov VN, Nikolaev DM, Panov MS, Linnik SA, Mereshchenko AS, Kochemirovsky VA, Vasin AV, Ryazantsev MN.
PMID: 34884976
Int J Mol Sci. 2021 Dec 06;22(23). doi: 10.3390/ijms222313171.

Azobenzene/tetraethyl ammonium photochromic ligands (ATPLs) are photoactive compounds with a large variety of photopharmacological applications such as nociception control or vision restoration. Absorption band maximum and lifetime of the less stable isomer are important characteristics that determine the applicability...

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Strashkov DM, Mironov VN, Nikolaev DM, et al. Azobenzene/Tetraethyl Ammonium Photochromic Potassium Channel Blockers: Scope and Limitations for Design of Para-Substituted Derivatives with Specific Absorption Band Maxima and Thermal Isomerization Rate. Int J Mol Sci. 2021;22(23)doi: 10.3390/ijms222313171.
Strashkov, D. M., Mironov, V. N., Nikolaev, D. M., Panov, M. S., Linnik, S. A., Mereshchenko, A. S., Kochemirovsky, V. A., Vasin, A. V., & Ryazantsev, M. N. (2021). Azobenzene/Tetraethyl Ammonium Photochromic Potassium Channel Blockers: Scope and Limitations for Design of Para-Substituted Derivatives with Specific Absorption Band Maxima and Thermal Isomerization Rate. International journal of molecular sciences, 22(23), . https://doi.org/10.3390/ijms222313171
Strashkov, Daniil M, et al. "Azobenzene/Tetraethyl Ammonium Photochromic Potassium Channel Blockers: Scope and Limitations for Design of Para-Substituted Derivatives with Specific Absorption Band Maxima and Thermal Isomerization Rate." International journal of molecular sciences vol. 22,23 (2021). doi: https://doi.org/10.3390/ijms222313171
Strashkov DM, Mironov VN, Nikolaev DM, Panov MS, Linnik SA, Mereshchenko AS, Kochemirovsky VA, Vasin AV, Ryazantsev MN. Azobenzene/Tetraethyl Ammonium Photochromic Potassium Channel Blockers: Scope and Limitations for Design of Para-Substituted Derivatives with Specific Absorption Band Maxima and Thermal Isomerization Rate. Int J Mol Sci. 2021 Dec 06;22(23). doi: 10.3390/ijms222313171. PMID: 34884976.
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A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection.

Obesity medicine

AbdelMassih AF, Ye J, Kamel A, Mishriky F, Ismail HA, Ragab HA, El Qadi L, Malak L, Abdu M, El-Husseiny M, Ashraf M, Hafez N, AlShehry N, El-Husseiny N, AbdelRaouf N, Shebl N, Hafez N, Youssef N, Afdal P, Hozaien R, Menshawey R, Saeed R, Fouda R.
PMID: 32835124
Obes Med. 2020 Sep;19:100281. doi: 10.1016/j.obmed.2020.100281. Epub 2020 Jul 15.

Furin, a cleavage enzyme, is increasingly recognized in the pathogenesis of metabolic syndrome. Its cleavage action is an essential activation step for the endothelial pathogenicity of several viruses including SARS-CoV-2. This Furin-mediated endothelial tropism seems to underlie the multi-organ...

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AbdelMassih AF, Ye J, Kamel A, et al. A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection. Obes Med. 2020;19:100281doi: 10.1016/j.obmed.2020.100281.
AbdelMassih, A. F., Ye, J., Kamel, A., Mishriky, F., Ismail, H. A., Ragab, H. A., El Qadi, L., Malak, L., Abdu, M., El-Husseiny, M., Ashraf, M., Hafez, N., AlShehry, N., El-Husseiny, N., AbdelRaouf, N., Shebl, N., Hafez, N., Youssef, N., Afdal, P., Hozaien, R., Menshawey, R., Saeed, R., & Fouda, R. (2020). A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection. Obesity medicine, 19100281. https://doi.org/10.1016/j.obmed.2020.100281
AbdelMassih, Antoine Fakhry, et al. "A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection." Obesity medicine vol. 19 (2020): 100281. doi: https://doi.org/10.1016/j.obmed.2020.100281
AbdelMassih AF, Ye J, Kamel A, Mishriky F, Ismail HA, Ragab HA, El Qadi L, Malak L, Abdu M, El-Husseiny M, Ashraf M, Hafez N, AlShehry N, El-Husseiny N, AbdelRaouf N, Shebl N, Hafez N, Youssef N, Afdal P, Hozaien R, Menshawey R, Saeed R, Fouda R. A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection. Obes Med. 2020 Sep;19:100281. doi: 10.1016/j.obmed.2020.100281. Epub 2020 Jul 15. PMID: 32835124; PMCID: PMC7362855.
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A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection.

Obesity medicine

AbdelMassih AF, Ye J, Kamel A, Mishriky F, Ismail HA, Ragab HA, El Qadi L, Malak L, Abdu M, El-Husseiny M, Ashraf M, Hafez N, AlShehry N, El-Husseiny N, AbdelRaouf N, Shebl N, Hafez N, Youssef N, Afdal P, Hozaien R, Menshawey R, Saeed R, Fouda R.
PMID: 32835124
Obes Med. 2020 Sep;19:100281. doi: 10.1016/j.obmed.2020.100281. Epub 2020 Jul 15.

Furin, a cleavage enzyme, is increasingly recognized in the pathogenesis of metabolic syndrome. Its cleavage action is an essential activation step for the endothelial pathogenicity of several viruses including SARS-CoV-2. This Furin-mediated endothelial tropism seems to underlie the multi-organ...

Cite
AbdelMassih AF, Ye J, Kamel A, et al. A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection. Obes Med. 2020;19:100281doi: 10.1016/j.obmed.2020.100281.
AbdelMassih, A. F., Ye, J., Kamel, A., Mishriky, F., Ismail, H. A., Ragab, H. A., El Qadi, L., Malak, L., Abdu, M., El-Husseiny, M., Ashraf, M., Hafez, N., AlShehry, N., El-Husseiny, N., AbdelRaouf, N., Shebl, N., Hafez, N., Youssef, N., Afdal, P., Hozaien, R., Menshawey, R., Saeed, R., & Fouda, R. (2020). A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection. Obesity medicine, 19100281. https://doi.org/10.1016/j.obmed.2020.100281
AbdelMassih, Antoine Fakhry, et al. "A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection." Obesity medicine vol. 19 (2020): 100281. doi: https://doi.org/10.1016/j.obmed.2020.100281
AbdelMassih AF, Ye J, Kamel A, Mishriky F, Ismail HA, Ragab HA, El Qadi L, Malak L, Abdu M, El-Husseiny M, Ashraf M, Hafez N, AlShehry N, El-Husseiny N, AbdelRaouf N, Shebl N, Hafez N, Youssef N, Afdal P, Hozaien R, Menshawey R, Saeed R, Fouda R. A multicenter consensus: A role of furin in the endothelial tropism in obese patients with COVID-19 infection. Obes Med. 2020 Sep;19:100281. doi: 10.1016/j.obmed.2020.100281. Epub 2020 Jul 15. PMID: 32835124; PMCID: PMC7362855.
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Showing 1 to 12 of 42 entries