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Showing 1 to 12 of 232 entries
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Rediscovering Pertussis.

Frontiers in pediatrics

Zlamy M.
PMID: 27376050
Front Pediatr. 2016 Jun 08;4:52. doi: 10.3389/fped.2016.00052. eCollection 2016.

Pertussis, caused by Bordetella (B.) pertussis, a Gram-negative bacterium, is a highly contagious airway infection. Especially in infants, pertussis remains a major health concern. Acute infection with B. pertussis can cause severe illness characterized by severe respiratory failure, pulmonary...

Multiple Signaling Pathways Contribute to the Thrombin-induced Secretory Phenotype in Vascular Smooth Muscle Cells.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Jeong JY, Son Y, Kim BY, Eo SK, Rhim BY, Kim K.
PMID: 26557022
Korean J Physiol Pharmacol. 2015 Nov;19(6):549-55. doi: 10.4196/kjpp.2015.19.6.549. Epub 2015 Oct 16.

We attempted to investigate molecular mechanisms underlying phenotypic change of vascular smooth muscle cells (VSMCs) by determining signaling molecules involved in chemokine production. Treatment of human aortic smooth muscle cells (HAoSMCs) with thrombin resulted not only in elevated transcription...

Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.

Molecular metabolism

Engelstoft MS, Park WM, Sakata I, Kristensen LV, Husted AS, Osborne-Lawrence S, Piper PK, Walker AK, Pedersen MH, Nøhr MK, Pan J, Sinz CJ, Carrington PE, Akiyama TE, Jones RM, Tang C, Ahmed K, Offermanns S, Egerod KL, Zigman JM, Schwartz TW.
PMID: 24327954
Mol Metab. 2013 Sep 04;2(4):376-92. doi: 10.1016/j.molmet.2013.08.006. eCollection 2013.

The molecular mechanisms regulating secretion of the orexigenic-glucoregulatory hormone ghrelin remain unclear. Based on qPCR analysis of FACS-purified gastric ghrelin cells, highly expressed and enriched 7TM receptors were comprehensively identified and functionally characterized using in vitro, ex vivo and...

Detection of Bordetella pertussis from Clinical Samples by Culture and End-Point PCR in Malaysian Patients.

International journal of bacteriology

Ting TX, Hashim R, Ahmad N, Abdullah KH.
PMID: 26904725
Int J Bacteriol. 2013;2013:324136. doi: 10.1155/2013/324136. Epub 2013 May 07.

Pertussis or whooping cough is a highly infectious respiratory disease caused by Bordetella pertussis. In vaccinating countries, infants, adolescents, and adults are relevant patients groups. A total of 707 clinical specimens were received from major hospitals in Malaysia in...

Effect and mechanism of the metastasis suppressor gene BRMS1 on the migration of breast cancer cells.

International journal of clinical and experimental medicine

Yang YL, Chen CZ, Jin LP, Ji QQ, Chen YZ, Li Q, Zhang XH, Qu JM.
PMID: 24260596
Int J Clin Exp Med. 2013 Oct 25;6(10):908-16. eCollection 2013.

OBJECTIVE: To study the effect of the transfected Breast cancer metastasis suppressor 1 (BRMS1) gene on the migration of breast cancer cells and the possible mechanisms involved.METHODS: MDA-MB-231HM cells which have a high propensity of metastasize to lung was...

Acute morphine alters GABAergic transmission in the central amygdala during naloxone-precipitated morphine withdrawal: role of cyclic AMP.

Frontiers in integrative neuroscience

Bajo M, Madamba SG, Roberto M, Siggins GR.
PMID: 24926240
Front Integr Neurosci. 2014 Jun 04;8:45. doi: 10.3389/fnint.2014.00045. eCollection 2014.

The central amygdala (CeA) plays an important role in opioid addiction. Therefore, we examined the effects of naloxone-precipitated morphine withdrawal (WD) on GABAergic transmission in rat CeA neurons using whole-cell recordings with naloxone in the bath. The basal frequency...

Characterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptoms.

Asian Pacific journal of tropical medicine

Orellana-Peralta F, Jacinto M, Pons MJ, Gomes C, Bada C, Reyes I, Del Valle Mendoza J, Ruiz J.
PMID: 26194831
Asian Pac J Trop Med. 2015 Jun;8(6):464-7. doi: 10.1016/j.apjtm.2015.05.013. Epub 2015 Jun 25.

OBJECTIVE: To characterize two Achromobacter xylosoxidans recovered from 2 patients diagnosed with pertussis during a Bordetella pertussis surveillance program.METHODS: Nasopharyngeal swabs from 2 children under 1 year of age with clinical suspicion of pertussis were analyzed by culture and...

Endothelin-evoked Release of Arachidonic Acid from Mouse Astrocytes in Primary Culture.

The European journal of neuroscience

Tencé M, Cordier J, Glowinski J, Prémont J.
PMID: 12106434
Eur J Neurosci. 1992;4(10):993-999. doi: 10.1111/j.1460-9568.1992.tb00125.x.

In striatal astrocytes, receptors for the vasoactive peptide endothelin (ET) are associated with several intracellular signalling pathways: ET-1 increases the breakdown of phosphoinositides, induces a sustained influx of Ca2+ and inhibits the isoproterenol-induced formation of cAMP (Marin et al.,...

NADH Oxidase Activity of Plasma Membranes of Soybean Hypocotyls Is Activated by Guanine Nucleotides.

Plant physiology

Morre DJ, Brightman AO, Barr R, Davidson M, Crane FL.
PMID: 12231849
Plant Physiol. 1993 Jun;102(2):595-602. doi: 10.1104/pp.102.2.595.

The activity of an auxin-stimulated NADH oxidase of the plasma membrane of hypocotyls of etiolated soybean (Glycine max Merr.) seedlings responded to guanine and other nucleotides, but in a manner that differed from that of enzymes coupled to the...

Expression of GTP-binding proteins and protein kinase C isozymes in platelet-like particles derived from megakaryoblastic leukemia cells (MEG-01).

Platelets

Nagata K, Okano Y, Nozawa Y.
PMID: 16793752
Platelets. 1998;9(5):291-6. doi: 10.1080/09537109876528.

The expression of the various GTP-binding proteins and protein kinase C (PKC) in the platelet-like particles produced by MEG-01 cells was analyzed by RT-PCR and immunoblotting. We selected 14 human low Mr GTPbinding proteins (LMW-GPs) and nine PKCs expressed...

Cell cycle analysis of Chinese hamster ovary cells stimulated by phosphatidic acid in serum-free culture.

Journal of bioscience and bioengineering

Yamaji H, Sakai K, Joho T, Izumoto E, Fukuda H.
PMID: 16233741
J Biosci Bioeng. 2004;98(6):487-9. doi: 10.1016/S1389-1723(05)00317-8.

When recombinant Chinese hamster ovary cells were treated with pertussis toxin or genistein, not only lysophosphatidic acid (LPA) but also phosphatidic acid (PA) failed to stimulate progression through the cell cycle in serum-free culture, suggesting that PA and LPA...

Interleukin-1beta and anaphylatoxins exert a synergistic effect on NGF expression by astrocytes.

Journal of neuroinflammation

Jauneau AC, Ischenko A, Chatagner A, Benard M, Chan P, Schouft MT, Patte C, Vaudry H, Fontaine M.
PMID: 16594997
J Neuroinflammation. 2006 Apr 04;3:8. doi: 10.1186/1742-2094-3-8.

C3a and C5a anaphylatoxins are proinflammatory polypeptides released during complement activation. They exert their biological activities through interaction with two G protein-coupled receptors named C3aR and C5aR, respectively. In the brain, these receptors are expressed on glial cells, and...

Showing 1 to 12 of 232 entries