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[Not Available].

Therapie

Chebane L, Tavassoli N, Bagheri H, Jean-LouisMontastruc.
PMID: 27393246
Therapie. 2010 Sep-Oct;65(5):447-58. doi: 10.2515/therapie/2010051.

OBJECTIVE: To analyse drugs inducing hyperglycemia by using data reported to the French spontaneous reporting system and recorded in the French PharmacoVigilance Database (FPVD).METHODS: All cases with a report of hyperglycemia and/or diabetes in the French database between 1985...

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Chebane L, Tavassoli N, Bagheri H, et al. Hyperglycémies d'origine médicamenteuse : étude dans la Base Nationale Française de PharmacoVigilance (BNPV). [Not Available]. Therapie. 2010;65(5):447-58doi: 10.2515/therapie/2010051.
Chebane, L., Tavassoli, N., Bagheri, H., Jean-LouisMontastruc. (2010). Hyperglycémies d'origine médicamenteuse : étude dans la Base Nationale Française de PharmacoVigilance (BNPV). [Not Available]. Therapie, 65(5), 447-58. https://doi.org/10.2515/therapie/2010051
Chebane, Leila, et al. "Hyperglycémies d'origine médicamenteuse : étude dans la Base Nationale Française de PharmacoVigilance (BNPV)." [Not Available]. Therapie vol. 65,5 (2010): 447-58. doi: https://doi.org/10.2515/therapie/2010051
Chebane L, Tavassoli N, Bagheri H, Jean-LouisMontastruc. Hyperglycémies d'origine médicamenteuse : étude dans la Base Nationale Française de PharmacoVigilance (BNPV). [Not Available]. Therapie. 2010 Sep-Oct;65(5):447-58. doi: 10.2515/therapie/2010051. French. PMID: 27393246.
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Trial of Pentamidine Isothionate in Kala-Azar Cases in the Patna Medical College Hospital (Preliminary Report).

The Indian medical gazette

Ghosal SM, Sinha YK.
PMID: 29014795
Ind Med Gaz. 1948 Jan;83(1):11-14.

No abstract available.

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Ghosal SM, Sinha YK. Trial of Pentamidine Isothionate in Kala-Azar Cases in the Patna Medical College Hospital (Preliminary Report). Ind Med Gaz. 1948;83(1):11-14
Ghosal, S. M., & Sinha, Y. K. (1948). Trial of Pentamidine Isothionate in Kala-Azar Cases in the Patna Medical College Hospital (Preliminary Report). The Indian medical gazette, 83(1), 11-14.
Ghosal, S M, and Sinha, Y K. "Trial of Pentamidine Isothionate in Kala-Azar Cases in the Patna Medical College Hospital (Preliminary Report)." The Indian medical gazette vol. 83,1 (1948): 11-14.
Ghosal SM, Sinha YK. Trial of Pentamidine Isothionate in Kala-Azar Cases in the Patna Medical College Hospital (Preliminary Report). Ind Med Gaz. 1948 Jan;83(1):11-14. PMID: 29014795; PMCID: PMC5190497.
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A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

Parasites & vectors

Sykes ML, Avery VM.
PMID: 19909542
Parasit Vectors. 2009 Nov 12;2(1):54. doi: 10.1186/1756-3305-2-54.

BACKGROUND: Human African Trypanosomiasis (HAT) is caused by two trypanosome species, Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Current drugs available for the treatment of HAT have significant issues related to toxicity, administration regimes with limited effectiveness across species...

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Sykes ML, Avery VM. A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. Parasit Vectors. 2009;2(1):54doi: 10.1186/1756-3305-2-54.
Sykes, M. L., & Avery, V. M. (2009). A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. Parasites & vectors, 2(1), 54. https://doi.org/10.1186/1756-3305-2-54
Sykes, Melissa L, and Avery, Vicky M. "A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427." Parasites & vectors vol. 2,1 (2009): 54. doi: https://doi.org/10.1186/1756-3305-2-54
Sykes ML, Avery VM. A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. Parasit Vectors. 2009 Nov 12;2(1):54. doi: 10.1186/1756-3305-2-54. PMID: 19909542; PMCID: PMC2781010.
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The development of drugs for treatment of sleeping sickness: a historical review.

Parasites & vectors

Steverding D.
PMID: 20219092
Parasit Vectors. 2010 Mar 10;3(1):15. doi: 10.1186/1756-3305-3-15.

Only four drugs are available for the chemotherapy of human African trypanosomiasis or sleeping sickness; Suramin, pentamidine, melarsoprol and eflornithine. The history of the development of these drugs is well known and documented. suramin, pentamidine and melarsoprol were developed...

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Steverding D. The development of drugs for treatment of sleeping sickness: a historical review. Parasit Vectors. 2010;3(1):15doi: 10.1186/1756-3305-3-15.
Steverding, D. (2010). The development of drugs for treatment of sleeping sickness: a historical review. Parasites & vectors, 3(1), 15. https://doi.org/10.1186/1756-3305-3-15
Steverding, Dietmar. "The development of drugs for treatment of sleeping sickness: a historical review." Parasites & vectors vol. 3,1 (2010): 15. doi: https://doi.org/10.1186/1756-3305-3-15
Steverding D. The development of drugs for treatment of sleeping sickness: a historical review. Parasit Vectors. 2010 Mar 10;3(1):15. doi: 10.1186/1756-3305-3-15. PMID: 20219092; PMCID: PMC2848007.
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Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit.

Evidence-based complementary and alternative medicine : eCAM

Falcao RA, do Nascimento PL, de Souza SA, da Silva TM, de Queiroz AC, da Matta CB, Moreira MS, Camara CA, Silva TM.
PMID: 23983783
Evid Based Complement Alternat Med. 2013;2013:460613. doi: 10.1155/2013/460613. Epub 2013 Jul 28.

Hyptis pectinata, popularly known in Brazil as "sambacaitá" or "canudinho," is an aromatic shrub largely grown in the northeast of Brazil. The leaves and bark are used in an infusion for the treatment of throat and skin inflammations, bacterial...

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Falcao RA, do Nascimento PL, de Souza SA, et al. Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit. Evid Based Complement Alternat Med. 2013;2013:460613doi: 10.1155/2013/460613.
Falcao, R. A., do Nascimento, P. L., de Souza, S. A., da Silva, T. M., de Queiroz, A. C., da Matta, C. B., Moreira, M. S., Camara, C. A., & Silva, T. M. (2013). Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit. Evidence-based complementary and alternative medicine : eCAM, 2013460613. https://doi.org/10.1155/2013/460613
Falcao, Rosangela A, et al. "Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit." Evidence-based complementary and alternative medicine : eCAM vol. 2013 (2013): 460613. doi: https://doi.org/10.1155/2013/460613
Falcao RA, do Nascimento PL, de Souza SA, da Silva TM, de Queiroz AC, da Matta CB, Moreira MS, Camara CA, Silva TM. Antileishmanial Phenylpropanoids from the Leaves of Hyptis pectinata (L.) Poit. Evid Based Complement Alternat Med. 2013;2013:460613. doi: 10.1155/2013/460613. Epub 2013 Jul 28. PMID: 23983783; PMCID: PMC3745876.
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Nebulized pentamidine-induced acute renal allograft dysfunction.

Case reports in transplantation

Prabhavalkar S, Masengu A, O'Rourke D, Shields J, Courtney A.
PMID: 23401840
Case Rep Transplant. 2013;2013:907593. doi: 10.1155/2013/907593. Epub 2013 Jan 17.

Acute kidney injury (AKI) is a recognised complication of intravenous pentamidine therapy. A direct nephrotoxic effect leading to acute tubular necrosis has been postulated. We report a case of severe renal allograft dysfunction due to nebulised pentamidine. The patient...

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Prabhavalkar S, Masengu A, O'Rourke D, et al. Nebulized pentamidine-induced acute renal allograft dysfunction. Case Rep Transplant. 2013;2013:907593doi: 10.1155/2013/907593.
Prabhavalkar, S., Masengu, A., O'Rourke, D., Shields, J., & Courtney, A. (2013). Nebulized pentamidine-induced acute renal allograft dysfunction. Case reports in transplantation, 2013907593. https://doi.org/10.1155/2013/907593
Prabhavalkar, Siddhesh, et al. "Nebulized pentamidine-induced acute renal allograft dysfunction." Case reports in transplantation vol. 2013 (2013): 907593. doi: https://doi.org/10.1155/2013/907593
Prabhavalkar S, Masengu A, O'Rourke D, Shields J, Courtney A. Nebulized pentamidine-induced acute renal allograft dysfunction. Case Rep Transplant. 2013;2013:907593. doi: 10.1155/2013/907593. Epub 2013 Jan 17. PMID: 23401840; PMCID: PMC3562641.
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Acute kidney injury in an infant with severe combined immunodeficiency: Answers.

Pediatric nephrology (Berlin, Germany)

Malakasioti G, Alders N, Lucchini G, Cheng IL, Bockenhauer D.
PMID: 31313001
Pediatr Nephrol. 2019 Dec;34(12):2541-2544. doi: 10.1007/s00467-019-04303-w. Epub 2019 Jul 16.

No abstract available.

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Malakasioti G, Alders N, Lucchini G, et al. Acute kidney injury in an infant with severe combined immunodeficiency: Answers. Pediatr Nephrol. 2019;34(12):2541-2544doi: 10.1007/s00467-019-04303-w.
Malakasioti, G., Alders, N., Lucchini, G., Cheng, I. L., & Bockenhauer, D. (2019). Acute kidney injury in an infant with severe combined immunodeficiency: Answers. Pediatric nephrology (Berlin, Germany), 34(12), 2541-2544. https://doi.org/10.1007/s00467-019-04303-w
Malakasioti, Georgia, et al. "Acute kidney injury in an infant with severe combined immunodeficiency: Answers." Pediatric nephrology (Berlin, Germany) vol. 34,12 (2019): 2541-2544. doi: https://doi.org/10.1007/s00467-019-04303-w
Malakasioti G, Alders N, Lucchini G, Cheng IL, Bockenhauer D. Acute kidney injury in an infant with severe combined immunodeficiency: Answers. Pediatr Nephrol. 2019 Dec;34(12):2541-2544. doi: 10.1007/s00467-019-04303-w. Epub 2019 Jul 16. PMID: 31313001.
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Visceral leishmaniasis triggering an adult-onset Still's disease: a unique case.

Clinical case reports

Spoto S, Costantino S, Valeriani E, Fogolari M, Cella E, Dicuonzo G, Ciccozzi M, Angeletti S.
PMID: 29225867
Clin Case Rep. 2017 Nov 13;5(12):2111-2116. doi: 10.1002/ccr3.1266. eCollection 2017 Dec.

Adult-onset Still's disease (AOSD) due to visceral leishmaniasis (VL) has not been previously reported. This case report analyzes a single episode of AOSD probably due to a visceral leishmaniasis successfully treated with pentamidine isethionate and prednisone.

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Spoto S, Costantino S, Valeriani E, et al. Visceral leishmaniasis triggering an adult-onset Still's disease: a unique case. Clin Case Rep. 2017;5(12):2111-2116doi: 10.1002/ccr3.1266.
Spoto, S., Costantino, S., Valeriani, E., Fogolari, M., Cella, E., Dicuonzo, G., Ciccozzi, M., & Angeletti, S. (2017). Visceral leishmaniasis triggering an adult-onset Still's disease: a unique case. Clinical case reports, 5(12), 2111-2116. https://doi.org/10.1002/ccr3.1266
Spoto, Silvia, et al. "Visceral leishmaniasis triggering an adult-onset Still's disease: a unique case." Clinical case reports vol. 5,12 (2017): 2111-2116. doi: https://doi.org/10.1002/ccr3.1266
Spoto S, Costantino S, Valeriani E, Fogolari M, Cella E, Dicuonzo G, Ciccozzi M, Angeletti S. Visceral leishmaniasis triggering an adult-onset Still's disease: a unique case. Clin Case Rep. 2017 Nov 13;5(12):2111-2116. doi: 10.1002/ccr3.1266. eCollection 2017 Dec. PMID: 29225867; PMCID: PMC5715570.
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Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report.

Open forum infectious diseases

Salameh A, Bello N, Becker J, Zangeneh T.
PMID: 26280011
Open Forum Infect Dis. 2015 Jul 10;2(3):ofv104. doi: 10.1093/ofid/ofv104. eCollection 2015 Sep.

Granulomatous amoebic encephalitis (GAE) due to Acanthamoeba is almost a uniformly fatal infection in immune-compromised hosts despite multidrug combination therapy. We report a case of GAE in a female who received a deceased donor kidney graft. She was treated...

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Salameh A, Bello N, Becker J, et al. Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report. Open Forum Infect Dis. 2015;2(3):ofv104doi: 10.1093/ofid/ofv104.
Salameh, A., Bello, N., Becker, J., & Zangeneh, T. (2015). Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report. Open forum infectious diseases, 2(3), ofv104. https://doi.org/10.1093/ofid/ofv104
Salameh, Ahmad, et al. "Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report." Open forum infectious diseases vol. 2,3 (2015): ofv104. doi: https://doi.org/10.1093/ofid/ofv104
Salameh A, Bello N, Becker J, Zangeneh T. Fatal Granulomatous Amoebic Encephalitis Caused by Acanthamoeba in a Patient With Kidney Transplant: A Case Report. Open Forum Infect Dis. 2015 Jul 10;2(3):ofv104. doi: 10.1093/ofid/ofv104. eCollection 2015 Sep. PMID: 26280011; PMCID: PMC4534522.
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Structure-Activity Studies with Bis-Amidines That Potentiate Gram-Positive Specific Antibiotics against Gram-Negative Pathogens.

ACS infectious diseases

Wesseling CMJ, Slingerland CJ, Veraar S, Lok S, Martin NI.
PMID: 34766746
ACS Infect Dis. 2021 Dec 10;7(12):3314-3335. doi: 10.1021/acsinfecdis.1c00466. Epub 2021 Nov 12.

Pentamidine, an FDA-approved antiparasitic drug, was recently identified as an outer membrane disrupting synergist that potentiates erythromycin, rifampicin, and novobiocin against Gram-negative bacteria. The same study also described a preliminary structure-activity relationship using commercially available pentamidine analogues. We here...

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Wesseling CMJ, Slingerland CJ, Veraar S, et al. Structure-Activity Studies with Bis-Amidines That Potentiate Gram-Positive Specific Antibiotics against Gram-Negative Pathogens. ACS Infect Dis. 2021;7(12):3314-3335doi: 10.1021/acsinfecdis.1c00466.
Wesseling, C. M. J., Slingerland, C. J., Veraar, S., Lok, S., & Martin, N. I. (2021). Structure-Activity Studies with Bis-Amidines That Potentiate Gram-Positive Specific Antibiotics against Gram-Negative Pathogens. ACS infectious diseases, 7(12), 3314-3335. https://doi.org/10.1021/acsinfecdis.1c00466
Wesseling, Charlotte M J, et al. "Structure-Activity Studies with Bis-Amidines That Potentiate Gram-Positive Specific Antibiotics against Gram-Negative Pathogens." ACS infectious diseases vol. 7,12 (2021): 3314-3335. doi: https://doi.org/10.1021/acsinfecdis.1c00466
Wesseling CMJ, Slingerland CJ, Veraar S, Lok S, Martin NI. Structure-Activity Studies with Bis-Amidines That Potentiate Gram-Positive Specific Antibiotics against Gram-Negative Pathogens. ACS Infect Dis. 2021 Dec 10;7(12):3314-3335. doi: 10.1021/acsinfecdis.1c00466. Epub 2021 Nov 12. PMID: 34766746.
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Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects.

PLoS neglected tropical diseases

Henry K, Mayet A, Hernandez M, Frechard G, Blanc PA, Schmitt M, André N, Loreau JM, Ginouves M, Prévot G, Couppié P, Demar M, Blaizot R.
PMID: 34797836
PLoS Negl Trop Dis. 2021 Nov 19;15(11):e0009938. doi: 10.1371/journal.pntd.0009938. eCollection 2021 Nov.

BACKGROUND: Cutaneous Leishmaniasis (CL) is endemic in French Guiana but cases are usually sporadic. An outbreak signal was issued on May 15th 2020 with 15 suspected cases after a military training course in the rainforest. An outbreak investigation was...

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Henry K, Mayet A, Hernandez M, et al. Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects. PLoS Negl Trop Dis. 2021;15(11):e0009938doi: 10.1371/journal.pntd.0009938.
Henry, K., Mayet, A., Hernandez, M., Frechard, G., Blanc, P. A., Schmitt, M., André, N., Loreau, J. M., Ginouves, M., Prévot, G., Couppié, P., Demar, M., & Blaizot, R. (2021). Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects. PLoS neglected tropical diseases, 15(11), e0009938. https://doi.org/10.1371/journal.pntd.0009938
Henry, Kim, et al. "Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects." PLoS neglected tropical diseases vol. 15,11 (2021): e0009938. doi: https://doi.org/10.1371/journal.pntd.0009938
Henry K, Mayet A, Hernandez M, Frechard G, Blanc PA, Schmitt M, André N, Loreau JM, Ginouves M, Prévot G, Couppié P, Demar M, Blaizot R. Outbreak of Cutaneous Leishmaniasis among military personnel in French Guiana, 2020: Clinical, phylogenetic, individual and environmental aspects. PLoS Negl Trop Dis. 2021 Nov 19;15(11):e0009938. doi: 10.1371/journal.pntd.0009938. eCollection 2021 Nov. PMID: 34797836; PMCID: PMC8641862.
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Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes.

Medicinal chemistry (Shariqah (United Arab Emirates))

de Aquino TM, França PHB, Rodrigues ÉEES, Nascimento IJS, Santos-Júnior PFS, Aquino PGV, Santos MS, Queiroz AC, Araújo MV, Alexandre-Moreira MS, Rodrigues RRL, Rodrigues KAF, Freitas JD, Bricard J, Meneghetti MR, Bourguignon JJ, Schmitt M, da Silva-Júnior EF, de Araújo-Júnior JX.
PMID: 33593264
Med Chem. 2021 Feb 16; doi: 10.2174/1573406417666210216154428. Epub 2021 Feb 16.

BACKGROUND: Leishmaniasis is a worldwide health problem, highly endemic in developing countries. Among the four main clinical forms of the disease, visceral leishmaniasis is the most severe, fatal in 95% of cases. The undesired side-effects from first-line chemotherapy and...

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de Aquino TM, França PHB, Rodrigues ÉEES, et al. Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes. Med Chem. 2021;doi: 10.2174/1573406417666210216154428.
de Aquino, T. M., França, P. H. B., Rodrigues, �. �. E. E. S., Nascimento, I. J. S., Santos-Júnior, P. F. S., Aquino, P. G. V., Santos, M. S., Queiroz, A. C., Araújo, M. V., Alexandre-Moreira, M. S., Rodrigues, R. R. L., Rodrigues, K. A. F., Freitas, J. D., Bricard, J., Meneghetti, M. R., Bourguignon, J. J., Schmitt, M., da Silva-Júnior, E. F., & de Araújo-Júnior, J. X. (2021). Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes. Medicinal chemistry (Shariqah (United Arab Emirates)), . https://doi.org/10.2174/1573406417666210216154428
de Aquino, Thiago M, et al. "Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes." Medicinal chemistry (Shariqah (United Arab Emirates)) vol. (2021). doi: https://doi.org/10.2174/1573406417666210216154428
de Aquino TM, França PHB, Rodrigues ÉEES, Nascimento IJS, Santos-Júnior PFS, Aquino PGV, Santos MS, Queiroz AC, Araújo MV, Alexandre-Moreira MS, Rodrigues RRL, Rodrigues KAF, Freitas JD, Bricard J, Meneghetti MR, Bourguignon JJ, Schmitt M, da Silva-Júnior EF, de Araújo-Júnior JX. Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes. Med Chem. 2021 Feb 16; doi: 10.2174/1573406417666210216154428. Epub 2021 Feb 16. PMID: 33593264.
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