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Carbon Monoxide-Neuroglobin Axis Targeting Metabolism Against Inflammation in BV-2 Microglial Cells.

Molecular neurobiology

Dias-Pedroso D, Ramalho JS, Sardão VA, Jones JG, Romão CC, Oliveira PJ, Vieira HLA.
PMID: 34797521
Mol Neurobiol. 2021 Nov 19; doi: 10.1007/s12035-021-02630-4. Epub 2021 Nov 19.

Microglia are the immune competent cell of the central nervous system (CNS), promoting brain homeostasis and regulating inflammatory response against infection and injury. Chronic or exacerbated neuroinflammation is a cause of damage in several brain pathologies. Endogenous carbon monoxide...

A simple method for quantifying de novo lipogenesis rate and substrate selection in cell cultures by .

NMR in biomedicine

Patrício JS, Dias-Pedroso D, Carvalho RA, Viera HLA, Jones JG.
PMID: 34850989
NMR Biomed. 2021 Dec 01;e4648. doi: 10.1002/nbm.4648. Epub 2021 Dec 01.

PURPOSE: De novo lipogenesis (DNL) is critical for cell growth and maintenance, and acetyl-CoA precursors can be derived from different substrates. We developed a METHODS: BV-2 microglial cell line cultured with glucose and glutamine was provided with [U-RESULTS: Glucose...

Showing 1 to 2 of 2 entries