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Showing 1 to 12 of 20 entries
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PET Imaging of Angiogenesis.

PET clinics

Niu G, Chen X.
PMID: 20046926
PET Clin. 2009 Jan 01;4(1):17-38. doi: 10.1016/j.cpet.2009.04.011.

Angiogenesis is a highly-controlled process that is dependent on the intricate balance of both promoting and inhibiting factors, involved in various physiological and pathological processes. A comprehensive understanding of the molecular mechanisms that regulate angiogenesis has resulted in the...

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Niu G, Chen X. PET Imaging of Angiogenesis. PET Clin. 2009;4(1):17-38doi: 10.1016/j.cpet.2009.04.011.
Niu, G., & Chen, X. (2009). PET Imaging of Angiogenesis. PET clinics, 4(1), 17-38. https://doi.org/10.1016/j.cpet.2009.04.011
Niu, Gang, and Chen, Xiaoyuan. "PET Imaging of Angiogenesis." PET clinics vol. 4,1 (2009): 17-38. doi: https://doi.org/10.1016/j.cpet.2009.04.011
Niu G, Chen X. PET Imaging of Angiogenesis. PET Clin. 2009 Jan 01;4(1):17-38. doi: 10.1016/j.cpet.2009.04.011. PMID: 20046926; PMCID: PMC2753532.
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In situ study of the impact of inter- and intra-reader variability on region of interest (ROI) analysis in preclinical molecular imaging.

American journal of nuclear medicine and molecular imaging

Habte F, Budhiraja S, Keren S, Doyle TC, Levin CS, Paik DS.
PMID: 23526701
Am J Nucl Med Mol Imaging. 2013;3(2):175-81. Epub 2013 Mar 08.

We estimated reader-dependent variability of region of interest (ROI) analysis and evaluated its impact on preclinical quantitative molecular imaging. To estimate reader variability, we used five independent image datasets acquired each using microPET and multispectral fluorescence imaging (MSFI). We...

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Habte F, Budhiraja S, Keren S, et al. In situ study of the impact of inter- and intra-reader variability on region of interest (ROI) analysis in preclinical molecular imaging. Am J Nucl Med Mol Imaging. 2013;3(2):175-81
Habte, F., Budhiraja, S., Keren, S., Doyle, T. C., Levin, C. S., & Paik, D. S. (2013). In situ study of the impact of inter- and intra-reader variability on region of interest (ROI) analysis in preclinical molecular imaging. American journal of nuclear medicine and molecular imaging, 3(2), 175-81.
Habte, Frezghi, et al. "In situ study of the impact of inter- and intra-reader variability on region of interest (ROI) analysis in preclinical molecular imaging." American journal of nuclear medicine and molecular imaging vol. 3,2 (2013): 175-81.
Habte F, Budhiraja S, Keren S, Doyle TC, Levin CS, Paik DS. In situ study of the impact of inter- and intra-reader variability on region of interest (ROI) analysis in preclinical molecular imaging. Am J Nucl Med Mol Imaging. 2013;3(2):175-81. Epub 2013 Mar 08. PMID: 23526701; PMCID: PMC3601477.
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Cellulose Nanoparticles are a Biodegradable Photoacoustic Contrast Agent for Use in Living Mice.

Photoacoustics

Jokerst JV, Van de Sompel D, Bohndiek SE, Gambhir SS.
PMID: 25225633
Photoacoustics. 2014 Sep 01;2(3):119-127. doi: 10.1016/j.pacs.2014.07.001.

Molecular imaging with photoacoustic ultrasound is an emerging field that combines the spatial and temporal resolution of ultrasound with the contrast of optical imaging. However, there are few imaging agents that offer both high signal intensity and biodegradation into...

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Jokerst JV, Van de Sompel D, Bohndiek SE, et al. Cellulose Nanoparticles are a Biodegradable Photoacoustic Contrast Agent for Use in Living Mice. Photoacoustics. 2014;2(3):119-127doi: 10.1016/j.pacs.2014.07.001.
Jokerst, J. V., Van de Sompel, D., Bohndiek, S. E., & Gambhir, S. S. (2014). Cellulose Nanoparticles are a Biodegradable Photoacoustic Contrast Agent for Use in Living Mice. Photoacoustics, 2(3), 119-127. https://doi.org/10.1016/j.pacs.2014.07.001
Jokerst, Jesse V, et al. "Cellulose Nanoparticles are a Biodegradable Photoacoustic Contrast Agent for Use in Living Mice." Photoacoustics vol. 2,3 (2014): 119-127. doi: https://doi.org/10.1016/j.pacs.2014.07.001
Jokerst JV, Van de Sompel D, Bohndiek SE, Gambhir SS. Cellulose Nanoparticles are a Biodegradable Photoacoustic Contrast Agent for Use in Living Mice. Photoacoustics. 2014 Sep 01;2(3):119-127. doi: 10.1016/j.pacs.2014.07.001. PMID: 25225633; PMCID: PMC4161983.
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Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors.

EJNMMI research

Shen B, James ML, Andrews L, Lau C, Chen S, Palner M, Miao Z, Arksey NC, Shuhendler AJ, Scatliffe S, Kaneshige K, Parsons SM, McCurdy CR, Salehi A, Gambhir SS, Chin FT.
PMID: 26384292
EJNMMI Res. 2015 Dec;5(1):49. doi: 10.1186/s13550-015-0122-2. Epub 2015 Sep 17.

BACKGROUND: This study aims to further evaluate the specificity and selectivity of [(18)F]FTC-146 and obtain additional data to support its clinical translation.METHODS: The binding of [(19)F]FTC-146 to vesicular acetylcholine transporter (VAChT) was evaluated using [(3)H]vesamicol and PC12(A123.7) cells in...

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Shen B, James ML, Andrews L, et al. Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors. EJNMMI Res. 2015;5(1):49doi: 10.1186/s13550-015-0122-2.
Shen, B., James, M. L., Andrews, L., Lau, C., Chen, S., Palner, M., Miao, Z., Arksey, N. C., Shuhendler, A. J., Scatliffe, S., Kaneshige, K., Parsons, S. M., McCurdy, C. R., Salehi, A., Gambhir, S. S., & Chin, F. T. (2015). Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors. EJNMMI research, 5(1), 49. https://doi.org/10.1186/s13550-015-0122-2
Shen, Bin, et al. "Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors." EJNMMI research vol. 5,1 (2015): 49. doi: https://doi.org/10.1186/s13550-015-0122-2
Shen B, James ML, Andrews L, Lau C, Chen S, Palner M, Miao Z, Arksey NC, Shuhendler AJ, Scatliffe S, Kaneshige K, Parsons SM, McCurdy CR, Salehi A, Gambhir SS, Chin FT. Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors. EJNMMI Res. 2015 Dec;5(1):49. doi: 10.1186/s13550-015-0122-2. Epub 2015 Sep 17. PMID: 26384292; PMCID: PMC4573970.
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Initial evaluation of (4S)-4-(3-[.

EJNMMI research

Park SY, Mosci C, Kumar M, Wardak M, Koglin N, Bullich S, Mueller A, Berndt M, Stephens AW, Chin FT, Gambhir SS, Mittra ES.
PMID: 32857284
EJNMMI Res. 2020 Aug 28;10(1):100. doi: 10.1186/s13550-020-00678-2.

PURPOSE: (4S)-4-(3-[METHODS: A total of 15 subjects with HNC (n = 5), CRC (n = 5), or NHL (n = 5) were recruited (mean age 66.2 years, range 44-87 years). 301.4 ± 28.1 MBq (8.1 ± 0.8 mCi) of...

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Park SY, Mosci C, Kumar M, et al. Initial evaluation of (4S)-4-(3-[. EJNMMI Res. 2020;10(1):100doi: 10.1186/s13550-020-00678-2.
Park, S. Y., Mosci, C., Kumar, M., Wardak, M., Koglin, N., Bullich, S., Mueller, A., Berndt, M., Stephens, A. W., Chin, F. T., Gambhir, S. S., & Mittra, E. S. (2020). Initial evaluation of (4S)-4-(3-[. EJNMMI research, 10(1), 100. https://doi.org/10.1186/s13550-020-00678-2
Park, Sonya Y, et al. "Initial evaluation of (4S)-4-(3-[." EJNMMI research vol. 10,1 (2020): 100. doi: https://doi.org/10.1186/s13550-020-00678-2
Park SY, Mosci C, Kumar M, Wardak M, Koglin N, Bullich S, Mueller A, Berndt M, Stephens AW, Chin FT, Gambhir SS, Mittra ES. Initial evaluation of (4S)-4-(3-[. EJNMMI Res. 2020 Aug 28;10(1):100. doi: 10.1186/s13550-020-00678-2. PMID: 32857284; PMCID: PMC7455665.
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Ultra-selective carbon nanotubes for photoacoustic imaging of inflamed atherosclerotic plaques.

Advanced functional materials

Gifani M, Eddins DJ, Kosuge H, Zhang Y, Paluri SLA, Larson T, Leeper N, Herzenberg LA, Gambhir SS, McConnell MV, Ghosn EEB, Smith BR.
PMID: 34733130
Adv Funct Mater. 2021 Sep 09;31(37). doi: 10.1002/adfm.202101005. Epub 2021 Jun 17.

Disruption of vulnerable atherosclerotic plaques often leads to myocardial infarction and stroke, the leading causes of morbidity and mortality in the United States. A diagnostic method that detects high-risk atherosclerotic plaques at early stages could prevent these sequelae. The...

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Gifani M, Eddins DJ, Kosuge H, et al. Ultra-selective carbon nanotubes for photoacoustic imaging of inflamed atherosclerotic plaques. Adv Funct Mater. 2021;31(37)doi: 10.1002/adfm.202101005.
Gifani, M., Eddins, D. J., Kosuge, H., Zhang, Y., Paluri, S. L. A., Larson, T., Leeper, N., Herzenberg, L. A., Gambhir, S. S., McConnell, M. V., Ghosn, E. E. B., & Smith, B. R. (2021). Ultra-selective carbon nanotubes for photoacoustic imaging of inflamed atherosclerotic plaques. Advanced functional materials, 31(37), . https://doi.org/10.1002/adfm.202101005
Gifani, Mahsa, et al. "Ultra-selective carbon nanotubes for photoacoustic imaging of inflamed atherosclerotic plaques." Advanced functional materials vol. 31,37 (2021). doi: https://doi.org/10.1002/adfm.202101005
Gifani M, Eddins DJ, Kosuge H, Zhang Y, Paluri SLA, Larson T, Leeper N, Herzenberg LA, Gambhir SS, McConnell MV, Ghosn EEB, Smith BR. Ultra-selective carbon nanotubes for photoacoustic imaging of inflamed atherosclerotic plaques. Adv Funct Mater. 2021 Sep 09;31(37). doi: 10.1002/adfm.202101005. Epub 2021 Jun 17. PMID: 34733130; PMCID: PMC8559995.
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Novel dual-function near-infrared II fluorescence and PET probe for tumor delineation and image-guided surgery.

Chemical science

Sun Y, Zeng X, Xiao Y, Liu C, Zhu H, Zhou H, Chen Z, Xu F, Wang J, Zhu M, Wu J, Tian M, Zhang H, Deng Z, Cheng Z, Hong X.
PMID: 29675250
Chem Sci. 2018 Jan 08;9(8):2092-2097. doi: 10.1039/c7sc04774f. eCollection 2018 Feb 28.

Accurate tumor identification is essential in cancer management. Incomplete excision of tumor tissue, however, negatively affects the prognosis of the patient. To accomplish radical excision of tumor tissue, radiotracers can be used that target tumor tissue and can be...

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Sun Y, Zeng X, Xiao Y, et al. Novel dual-function near-infrared II fluorescence and PET probe for tumor delineation and image-guided surgery. Chem Sci. 2018;9(8):2092-2097doi: 10.1039/c7sc04774f.
Sun, Y., Zeng, X., Xiao, Y., Liu, C., Zhu, H., Zhou, H., Chen, Z., Xu, F., Wang, J., Zhu, M., Wu, J., Tian, M., Zhang, H., Deng, Z., Cheng, Z., & Hong, X. (2018). Novel dual-function near-infrared II fluorescence and PET probe for tumor delineation and image-guided surgery. Chemical science, 9(8), 2092-2097. https://doi.org/10.1039/c7sc04774f
Sun, Yao, et al. "Novel dual-function near-infrared II fluorescence and PET probe for tumor delineation and image-guided surgery." Chemical science vol. 9,8 (2018): 2092-2097. doi: https://doi.org/10.1039/c7sc04774f
Sun Y, Zeng X, Xiao Y, Liu C, Zhu H, Zhou H, Chen Z, Xu F, Wang J, Zhu M, Wu J, Tian M, Zhang H, Deng Z, Cheng Z, Hong X. Novel dual-function near-infrared II fluorescence and PET probe for tumor delineation and image-guided surgery. Chem Sci. 2018 Jan 08;9(8):2092-2097. doi: 10.1039/c7sc04774f. eCollection 2018 Feb 28. PMID: 29675250; PMCID: PMC5892408.
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Striatal dopamine D2/3 receptor regulation by stress inoculation in squirrel monkeys.

Neurobiology of stress

Lee AG, Nechvatal JM, Shen B, Buckmaster CL, Levy MJ, Chin FT, Schatzberg AF, Lyons DM.
PMID: 27981179
Neurobiol Stress. 2016 Feb 08;3:68-73. doi: 10.1016/j.ynstr.2016.02.001. eCollection 2016 Jun.

Intermittent mildly stressful situations provide opportunities to learn, practice, and improve coping in a process called stress inoculation. Stress inoculation also enhances cognitive control and response inhibition of impulsive motivated behavior. Cognitive control and motivation have been linked to...

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Lee AG, Nechvatal JM, Shen B, et al. Striatal dopamine D2/3 receptor regulation by stress inoculation in squirrel monkeys. Neurobiol Stress. 2016;3:68-73doi: 10.1016/j.ynstr.2016.02.001.
Lee, A. G., Nechvatal, J. M., Shen, B., Buckmaster, C. L., Levy, M. J., Chin, F. T., Schatzberg, A. F., & Lyons, D. M. (2016). Striatal dopamine D2/3 receptor regulation by stress inoculation in squirrel monkeys. Neurobiology of stress, 368-73. https://doi.org/10.1016/j.ynstr.2016.02.001
Lee, Alex G, et al. "Striatal dopamine D2/3 receptor regulation by stress inoculation in squirrel monkeys." Neurobiology of stress vol. 3 (2016): 68-73. doi: https://doi.org/10.1016/j.ynstr.2016.02.001
Lee AG, Nechvatal JM, Shen B, Buckmaster CL, Levy MJ, Chin FT, Schatzberg AF, Lyons DM. Striatal dopamine D2/3 receptor regulation by stress inoculation in squirrel monkeys. Neurobiol Stress. 2016 Feb 08;3:68-73. doi: 10.1016/j.ynstr.2016.02.001. eCollection 2016 Jun. PMID: 27981179; PMCID: PMC5146202.
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Quaternary Ammonium Salt Based NIR-II Probes for .

Advanced optical materials

Qu C, Xiao Y, Zhou H, Ding B, Li A, Lin J, Zeng X, Chen H, Qian K, Zhang X, Fang W, Wu J, Deng Z, Cheng Z, Hong X.
PMID: 32983835
Adv Opt Mater. 2019 Aug 05;7(15). doi: 10.1002/adom.201900229. Epub 2019 May 06.

Traditional luminescent materials including fluorescent probes suffer from notorious aggregation-caused quenching (ACQ) in aqueous solutions. Although several approaches such as the aggregation-induced emission (AIE) effect have been developed, it remains a significant challenge to identify an effective and efficient...

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Qu C, Xiao Y, Zhou H, et al. Quaternary Ammonium Salt Based NIR-II Probes for . Adv Opt Mater. 2019;7(15)doi: 10.1002/adom.201900229.
Qu, C., Xiao, Y., Zhou, H., Ding, B., Li, A., Lin, J., Zeng, X., Chen, H., Qian, K., Zhang, X., Fang, W., Wu, J., Deng, Z., Cheng, Z., & Hong, X. (2019). Quaternary Ammonium Salt Based NIR-II Probes for . Advanced optical materials, 7(15), . https://doi.org/10.1002/adom.201900229
Qu, Chunrong, et al. "Quaternary Ammonium Salt Based NIR-II Probes for ." Advanced optical materials vol. 7,15 (2019). doi: https://doi.org/10.1002/adom.201900229
Qu C, Xiao Y, Zhou H, Ding B, Li A, Lin J, Zeng X, Chen H, Qian K, Zhang X, Fang W, Wu J, Deng Z, Cheng Z, Hong X. Quaternary Ammonium Salt Based NIR-II Probes for . Adv Opt Mater. 2019 Aug 05;7(15). doi: 10.1002/adom.201900229. Epub 2019 May 06. PMID: 32983835; PMCID: PMC7517706.
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Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis.

Chemical science

Ye D, Shuhendler AJ, Pandit P, Brewer KD, Tee SS, Cui L, Tikhomirov G, Rutt B, Rao J.
PMID: 25429349
Chem Sci. 2014 Oct 01;4(10):3845-3852. doi: 10.1039/C4SC01392A.

Non-invasive detection of caspase-3/7 activity

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Ye D, Shuhendler AJ, Pandit P, et al. Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chem Sci. 2014;4(10):3845-3852doi: 10.1039/C4SC01392A.
Ye, D., Shuhendler, A. J., Pandit, P., Brewer, K. D., Tee, S. S., Cui, L., Tikhomirov, G., Rutt, B., & Rao, J. (2014). Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chemical science, 4(10), 3845-3852. https://doi.org/10.1039/C4SC01392A
Ye, Deju, et al. "Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis." Chemical science vol. 4,10 (2014): 3845-3852. doi: https://doi.org/10.1039/C4SC01392A
Ye D, Shuhendler AJ, Pandit P, Brewer KD, Tee SS, Cui L, Tikhomirov G, Rutt B, Rao J. Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chem Sci. 2014 Oct 01;4(10):3845-3852. doi: 10.1039/C4SC01392A. PMID: 25429349; PMCID: PMC4241271.
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MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell-Intrinsic and Host-Dependent Mechanisms.

Genes & cancer

Felsher DW.
PMID: 21037952
Genes Cancer. 2010 Jun;1(6):597-604. doi: 10.1177/1947601910377798.

Tumorigenesis is generally caused by genetic changes that activate oncogenes or inactivate tumor suppressor genes. The targeted inactivation of oncogenes can be associated with tumor regression through the phenomenon of oncogene addiction. One of the most common oncogenic events...

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Felsher DW. MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell-Intrinsic and Host-Dependent Mechanisms. Genes Cancer. 2010;1(6):597-604doi: 10.1177/1947601910377798.
Felsher, D. W. (2010). MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell-Intrinsic and Host-Dependent Mechanisms. Genes & cancer, 1(6), 597-604. https://doi.org/10.1177/1947601910377798
Felsher, Dean W. "MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell-Intrinsic and Host-Dependent Mechanisms." Genes & cancer vol. 1,6 (2010): 597-604. doi: https://doi.org/10.1177/1947601910377798
Felsher DW. MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell-Intrinsic and Host-Dependent Mechanisms. Genes Cancer. 2010 Jun;1(6):597-604. doi: 10.1177/1947601910377798. PMID: 21037952; PMCID: PMC2965623.
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InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible.

Nano research

Xie R, Chen K, Chen X, Peng X.
PMID: 20631914
Nano Res. 2008 Dec 14;1(6):457-464. doi: 10.1007/s12274-008-8048-x.

High quality InAs/InP/ZnSe core/shell/shell quantum dots have been grown by a one-pot approach. This engineered quantum dots with unique near-infrared (NIR) fluorescence, possessing outstanding optical properties, and the biocompatibility desired for in vivo applications. The resulting quantum dots have...

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Xie R, Chen K, Chen X, et al. InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible. Nano Res. 2008;1(6):457-464doi: 10.1007/s12274-008-8048-x.
Xie, R., Chen, K., Chen, X., & Peng, X. (2008). InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible. Nano research, 1(6), 457-464. https://doi.org/10.1007/s12274-008-8048-x
Xie, Renguo, et al. "InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible." Nano research vol. 1,6 (2008): 457-464. doi: https://doi.org/10.1007/s12274-008-8048-x
Xie R, Chen K, Chen X, Peng X. InAs/InP/ZnSe Core/Shell/Shell Quantum Dots as Near-Infrared Emitters: Bright, Narrow-Band, Non-Cadmium Containing, and Biocompatible. Nano Res. 2008 Dec 14;1(6):457-464. doi: 10.1007/s12274-008-8048-x. PMID: 20631914; PMCID: PMC2902876.
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Showing 1 to 12 of 20 entries