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Showing 1 to 12 of 114 entries
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Expression of estrogen receptor, progesterone receptor, and Ki67 in normal breast tissue in relation to subsequent risk of breast cancer.

NPJ breast cancer

Oh H, Eliassen AH, Wang M, Smith-Warner SA, Beck AH, Schnitt SJ, Collins LC, Connolly JL, Montaser-Kouhsari L, Polyak K, Tamimi RM.
PMID: 28111631
NPJ Breast Cancer. 2016;2. doi: 10.1038/npjbcancer.2016.32. Epub 2016 Oct 26.

Although expression of estrogen receptor (ER), progesterone receptor (PR), and cell proliferation marker Ki67 serve as predictive and prognostic factors in breast cancers, little is known about their roles in normal breast tissue. Here in a nested case-control study...

Adiposity throughout adulthood and risk of sudden cardiac death in women.

JACC. Clinical electrophysiology

Chiuve SE, Sun Q, Sandhu RK, Tedrow U, Cook NR, Manson JE, Albert CM.
PMID: 26824079
JACC Clin Electrophysiol. 2015 Dec 01;1(6):520-528. doi: 10.1016/j.jacep.2015.07.011.

BACKGROUND: Sudden cardiac death (SCD) is often the first manifestation of coronary heart disease (CHD) among women. Data regarding BMI and risk of SCD are limited and conflicting.OBJECTIVES: We examined the association of BMI repeatedly measured over 32 years...

Evidence of differential effects of vitamin d receptor variants on epithelial ovarian cancer risk by predicted vitamin d status.

Frontiers in oncology

Prescott J, Bertrand KA, Reid BM, Permuth-Wey J, De Vivo I, Cramer DW, Terry KL, Tworoger SS.
PMID: 25368842
Front Oncol. 2014 Oct 20;4:286. doi: 10.3389/fonc.2014.00286. eCollection 2014.

INTRODUCTION: Experimental studies suggest vitamin D inhibits ovarian carcinogenesis. Yet, epidemiologic studies of ovarian cancer risk and lifestyle correlates of vitamin D status, plasma 25-hydroxyvitamin D [25(OH)D], or vitamin D receptor (VDR) variants have been inconsistent.OBJECTIVE: To evaluate VDR...

Ogino et Al. Respond to "the 21st century epidemiologist".

American journal of epidemiology

Ogino S, Beck AH, King EE, Sherman ME, Milner DA, Giovannucci E.
PMID: 22935516
Am J Epidemiol. 2012 Oct 15;176(8):672-4. doi: 10.1093/aje/kws229. Epub 2012 Aug 30.

No abstract available.

Interdisciplinary education to integrate pathology and epidemiology: towards molecular and population-level health science.

American journal of epidemiology

Ogino S, King EE, Beck AH, Sherman ME, Milner DA, Giovannucci E.
PMID: 22935517
Am J Epidemiol. 2012 Oct 15;176(8):659-67. doi: 10.1093/aje/kws226. Epub 2012 Aug 30.

In recent decades, epidemiology, public health, and medical sciences have been increasingly compartmentalized into narrower disciplines. The authors recognize the value of integration of divergent scientific fields in order to create new methods, concepts, paradigms, and knowledge. Herein they...

Continuity of transcriptomes among colorectal cancer subtypes based on meta-analysis.

Genome biology

Ma S, Ogino S, Parsana P, Nishihara R, Qian Z, Shen J, Mima K, Masugi Y, Cao Y, Nowak JA, Shima K, Hoshida Y, Giovannucci EL, Gala MK, Chan AT, Fuchs CS, Parmigiani G, Huttenhower C, Waldron L.
PMID: 30253799
Genome Biol. 2018 Sep 25;19(1):142. doi: 10.1186/s13059-018-1511-4.

BACKGROUND: Previous approaches to defining subtypes of colorectal carcinoma (CRC) and other cancers based on transcriptomes have assumed the existence of discrete subtypes. We analyze gene expression patterns of colorectal tumors from a large number of patients to test...

Validation of a risk prediction tool for coronary heart disease in middle-aged women.

BMC women's health

De Vito KM, Baer HJ, Dart H, Chiuve SE, Rimm EB, Colditz GA.
PMID: 26552598
BMC Womens Health. 2015 Nov 10;15:101. doi: 10.1186/s12905-015-0250-x.

BACKGROUND: Health risk appraisal tools may be useful for identifying individuals who would benefit from lifestyle changes and increased surveillance. We evaluated the validity of the Your Disease Risk tool (YDR) for estimating relative risk of coronary heart disease...

Metabolomics in epidemiologic research: challenges and opportunities for early-career epidemiologists.

Metabolomics : Official journal of the Metabolomic Society

van Roekel EH, Loftfield E, Kelly RS, Zeleznik OA, Zanetti KA.
PMID: 30830482
Metabolomics. 2019 Jan 07;15(1):9. doi: 10.1007/s11306-018-1468-z.

BACKGROUND: The application of metabolomics to epidemiologic studies is increasing.AIM OF REVIEW: Here, we describe the challenges and opportunities facing early-career epidemiologists aiming to apply metabolomics to their research.KEY SCIENTIFIC CONCEPTS OF REVIEW: Many challenges inherent to metabolomics may...

Exploratory Genome-Wide Interaction Analysis of Nonsteroidal Anti-inflammatory Drugs and Predicted Gene Expression on Colorectal Cancer Risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Wang X, Su YR, Petersen PS, Bien S, Schmit SL, Drew DA, Albanes D, Berndt SI, Brenner H, Campbell PT, Casey G, Chang-Claude J, Gallinger SJ, Gruber SB, Haile RW, Harrison TA, Hoffmeister M, Jacobs EJ, Jenkins MA, Joshi AD, Li L, Lin Y, Lindor NM, Marchand LL, Martin V, Milne R, Maclnnis R, Moreno V, Nan H, Newcomb PA, Potter JD, Rennert G, Rennert H, Slattery ML, Thibodeau SN, Weinstein SJ, Woods MO, Chan AT, White E, Hsu L, Peters U.
PMID: 32651213
Cancer Epidemiol Biomarkers Prev. 2020 Sep;29(9):1800-1808. doi: 10.1158/1055-9965.EPI-19-1018. Epub 2020 Jul 10.

BACKGROUND: Regular use of nonsteroidal anti-inflammatory drugs (NSAID) is associated with lower risk of colorectal cancer. Genome-wide interaction analysis on single variants (G × E) has identified several SNPs that may interact with NSAIDs to confer colorectal cancer risk,...

Association of .

Clinical cancer research : an official journal of the American Association for Cancer Research

Borowsky J, Haruki K, Lau MC, Dias Costa A, Väyrynen JP, Ugai T, Arima K, da Silva A, Felt KD, Zhao M, Gurjao C, Twombly TS, Fujiyoshi K, Väyrynen SA, Hamada T, Mima K, Bullman S, Harrison TA, Phipps AI, Peters U, Ng K, Meyerhardt JA, Song M, Giovannucci EL, Wu K, Zhang X, Freeman GJ, Huttenhower C, Garrett WS, Chan AT, Leggett BA, Whitehall VLJ, Walker N, Brown I, Bettington M, Nishihara R, Fuchs CS, Lennerz JK, Giannakis M, Nowak JA, Ogino S.
PMID: 33632927
Clin Cancer Res. 2021 May 15;27(10):2816-2826. doi: 10.1158/1078-0432.CCR-20-4009. Epub 2021 Feb 25.

PURPOSE: While evidence indicates that EXPERIMENTAL DESIGN: We measured RESULTS: The amount of CONCLUSIONS: The amount of tissue

Genetic architectures of proximal and distal colorectal cancer are partly distinct.

Gut

Huyghe JR, Harrison TA, Bien SA, Hampel H, Figueiredo JC, Schmit SL, Conti DV, Chen S, Qu C, Lin Y, Barfield R, Baron JA, Cross AJ, Diergaarde B, Duggan D, Harlid S, Imaz L, Kang HM, Levine DM, Perduca V, Perez-Cornago A, Sakoda LC, Schumacher FR, Slattery ML, Toland AE, van Duijnhoven FJB, Van Guelpen B, Agudo A, Albanes D, Alonso MH, Anderson K, Arnau-Collell C, Arndt V, Banbury BL, Bassik MC, Berndt SI, Bézieau S, Bishop DT, Boehm J, Boeing H, Boutron-Ruault MC, Brenner H, Brezina S, Buch S, Buchanan DD, Burnett-Hartman A, Caan BJ, Campbell PT, Carr PR, Castells A, Castellví-Bel S, Chan AT, Chang-Claude J, Chanock SJ, Curtis KR, de la Chapelle A, Easton DF, English DR, Feskens EJM, Gala M, Gallinger SJ, Gauderman WJ, Giles GG, Goodman PJ, Grady WM, Grove JS, Gsur A, Gunter MJ, Haile RW, Hampe J, Hoffmeister M, Hopper JL, Hsu WL, Huang WY, Hudson TJ, Jenab M, Jenkins MA, Joshi AD, Keku TO, Kooperberg C, Kühn T, Küry S, Le Marchand L, Lejbkowicz F, Li CI, Li L, Lieb W, Lindblom A, Lindor NM, Männistö S, Markowitz SD, Milne RL, Moreno L, Murphy N, Nassir R, Offit K, Ogino S, Panico S, Parfrey PS, Pearlman R, Pharoah PDP, Phipps AI, Platz EA, Potter JD, Prentice RL, Qi L, Raskin L, Rennert G, Rennert HS, Riboli E, Schafmayer C, Schoen RE, Seminara D, Song M, Su YR, Tangen CM, Thibodeau SN, Thomas DC, Trichopoulou A, Ulrich CM, Visvanathan K, Vodicka P, Vodickova L, Vymetalkova V, Weigl K, Weinstein SJ, White E, Wolk A, Woods MO, Wu AH, Abecasis GR, Nickerson DA, Scacheri PC, Kundaje A, Casey G, Gruber SB, Hsu L, Moreno V, Hayes RB, Newcomb PA, Peters U.
PMID: 33632709
Gut. 2021 Jul;70(7):1325-1334. doi: 10.1136/gutjnl-2020-321534. Epub 2021 Feb 25.

OBJECTIVE: An understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision prevention, including individualized screening recommendations and the discovery of novel drug targets and repurposable drug candidates for chemoprevention. Known differences in molecular characteristics...

Common Analgesic Use for Menstrual Pain and Ovarian Cancer Risk.

Cancer prevention research (Philadelphia, Pa.)

Sasamoto N, Babic A, Vitonis AF, Titus L, Cramer DW, Trabert B, Tworoger SS, Terry KL.
PMID: 34244153
Cancer Prev Res (Phila). 2021 Aug;14(8):795-802. doi: 10.1158/1940-6207.CAPR-21-0090. Epub 2021 Jul 09.

Menstrual pain has been associated with increased ovarian cancer risk, presumably through increased inflammation, which is known to play a critical role in ovarian carcinogenesis. Analgesic medications are frequently used to treat menstrual pain, some of which lower ovarian...

Showing 1 to 12 of 114 entries