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Showing 1 to 12 of 1115 entries
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… of Osteopontin11Grant 12078 from the Canadian Breast Cancer Research Initiative (AFC and ABT) ALA is supported by the HL Holmes Postdoctoral Award from the …

postdoctoral

Allan AL.
GSID: H7U7pfB--dEJ
KA Furger, AL Allan, SM Wilson, C Hota… - Molecular Cancer …, 2003 - AACR

Osteopontin (OPN) is a secreted phosphoprotein that has been associated with malignancy of breast and other cancers. OPN binds to several cell surface integrins including α v β 3 , α …

In vitro evaluation of osteoprotegerin in chitosan for potential bone defect applications.

PeerJ

Jayash SN, Hashim NM, Misran M, Baharuddin NA.
PMID: 27635307
PeerJ. 2016 Aug 23;4:e2229. doi: 10.7717/peerj.2229. eCollection 2016.

BACKGROUND: The receptor activator of nuclear factor kappa-B (RANK)/RANK ligand/osteoprotegerin (OPG) system plays a critical role in bone remodelling by regulating osteoclast formation and activity. OPG has been used systemically in the treatment of bone diseases. In searching for...

Correction: Baseline Serum Osteopontin Levels Predict the Clinical Effectiveness of Tocilizumab but Not Infliximab in Biologic-Naïve Patients with Rheumatoid Arthritis: A Single-Center Prospective Study at 1 Year (the Keio First-Bio Cohort Study).

PloS one

Izumi K, Kaneko Y, Hashizume M, Yoshimoto K, Takeuchi T.
PMID: 26999019
PLoS One. 2016 Mar 21;11(3):e0152341. doi: 10.1371/journal.pone.0152341. eCollection 2016.

No abstract available.

Increased Expression of Osteopontin in Retinal Degeneration Induced by Blue Light-Emitting Diode Exposure in Mice.

Frontiers in molecular neuroscience

Chang SW, Kim HI, Kim GH, Park SJ, Kim IB.
PMID: 27504084
Front Mol Neurosci. 2016 Jul 25;9:58. doi: 10.3389/fnmol.2016.00058. eCollection 2016.

Osteopontin (OPN) is a multifunctional adhesive glycoprotein that is implicated in a variety of pro-inflammatory as well as neuroprotective and repair-promoting effects in the brain. As a first step towards understanding the role of OPN in retinal degeneration (RD),...

Angiotensin II suppresses osteoblastic differentiation and mineralized nodule formation via AT1 receptor in ROS17/2.8 cells.

Archives of medical science : AMS

Nakai K, Kawato T, Morita T, Yamazaki Y, Tanaka H, Tonogi M, Oki H, Maeno M.
PMID: 26170858
Arch Med Sci. 2015 Jun 19;11(3):628-37. doi: 10.5114/aoms.2015.52369.

INTRODUCTION: Angiotensin II (Ang II) not only regulates systemic blood pressure through a vasoconstrictive effect, but also promotes bone resorption. We recently reported that Ang II (10(-6) M) stimulated the production of matrix metalloproteinases via the AT1 receptor in...

Human Milk: Bioactive Proteins/Peptides and Functional Properties.

Nestle Nutrition Institute workshop series

Lönnerdal B.
PMID: 27337145
Nestle Nutr Inst Workshop Ser. 2016;86:97-107. doi: 10.1159/000442729. Epub 2016 Jun 23.

Breastfeeding has been associated with many benefits, both in the short and in the long term. Infants being breastfed generally have less illness and have better cognitive development at 1 year of age than formula-fed infants. Later in life,...

Gingipains from Porphyromonas gingivalis promote the transformation and proliferation of vascular smooth muscle cell phenotypes.

International journal of clinical and experimental medicine

Cao C, Ji X, Luo X, Zhong L.
PMID: 26770435
Int J Clin Exp Med. 2015 Oct 15;8(10):18327-34. eCollection 2015.

The aim of the present study was to ascertain the effect of Porphyromonas gingivalis cysteine protease gingipain on the proliferation of rat aortic smooth muscle cells (RASMCs). Gingipains were isolated and purified from the supernatant of P. gingivalis W83,...

Serum and tissue biomarkers in aortic stenosis.

Global cardiology science & practice

Kapelouzou A, Tsourelis L, Kaklamanis L, Degiannis D, Kogerakis N, Cokkinos DV.
PMID: 26779524
Glob Cardiol Sci Pract. 2015 Nov 13;2015(4):49. doi: 10.5339/gcsp.2015.49. eCollection 2015.

BACKGROUND: Calcific aortic valve stenosis (CAVS) is seen in a large proportion of individuals over 60 years. It is an active process, influenced by lipid accumulation, mechanical stress, inflammation, and abnormal extracellular matrix turnover. Various biomarkers (BMs) are studied,...

Osteopontin b and c isoforms: Molecular Candidates Associated with Leukemic Stem Cell Chemoresistance in Acute Myeloid Leukemia.

Asian Pacific journal of cancer prevention : APJCP

Mirzaei A, Mohammadi S, Ghaffari SH, Nikbakht M, Bashash D, Alimoghaddam K, Ghavamzadeh A.
PMID: 28670893
Asian Pac J Cancer Prev. 2017 Jun 25;18(6):1707-1715. doi: 10.22034/APJCP.2017.18.6.1707.

Despite impressive advances in therapeutic approaches, long-term survival with acute myeloid leukemia (AML) is low as a result of treatment resistance and frequent relapse. Among multitude oncogenic proteins involved in acquisition of a chemo-resistanr phenotype, osteopontin (OPN) recently has...

Correlation between lung neoplasm and serum level of osteopontin: A meta-analysis.

Biomedical reports

Li D, Qian W, Li RR, Zhang J, Li KE, Wu Y.
PMID: 27123248
Biomed Rep. 2016 May;4(5):567-572. doi: 10.3892/br.2016.619. Epub 2016 Feb 29.

The aim of this meta-analysis was to evaluate the clinical significance of serum osteopontin (OPN) levels in lung neoplasm in patients to establish a novel diagnostic score model. Articles were identified by searching the PubMed, Web of Science, Google...

Prognostic significance of osteopontin in patients with non-small cell lung cancer: results from a meta-analysis.

International journal of clinical and experimental medicine

Liu Y, Gu X, Lin Q, Tian T, Shao L, Yuan C, Zhang B, Fan K.
PMID: 26550190
Int J Clin Exp Med. 2015 Aug 15;8(8):12765-73. eCollection 2015.

BACKGROUNDS: Non-small cell lung cancer (NSCLC) is one of the most common malignancies with a high mortality level. Recently, a variety of studies explored the role of osteopontin (OPN) expression in the prognosis of NSCLC, but the results were...

Association of Salivary Osteopontin Levels with Glycaemic Status and Microalbuminuria - in Patients with Type 2 Diabetes Mellitus.

Journal of clinical and diagnostic research : JCDR

Gopal N, Rajagambeeram R, Venkatkumar S, Vijayan MV, Murugaiyan SB, Gopal SP, Ramsamy S, Alwar V.
PMID: 27656430
J Clin Diagn Res. 2016 Aug;10(8):BC06-8. doi: 10.7860/JCDR/2016/20156.8257. Epub 2016 Aug 01.

INTRODUCTION: The monitoring of glycaemic status in patients with T2DM is mainly through blood tests (Fasting plasma glucose and HbA1c), which are invasive and involves painful pricks. This leads to poor patient compliance and soon could lead to various...

Showing 1 to 12 of 1115 entries