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Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action.

Inorganic chemistry

Babak MV, Pfaffeneder-Kmen M, Meier-Menches SM, Legina MS, Theiner S, Licona C, Orvain C, Hejl M, Hanif M, Jakupec MA, Keppler BK, Gaiddon C, Hartinger CG.
PMID: 29442506
Inorg Chem. 2018 Mar 05;57(5):2851-2864. doi: 10.1021/acs.inorgchem.7b03210. Epub 2018 Feb 14.

Platinum-based anticancer coordination compounds are widely used in the treatment of many tumor types, where they are very effective but also cause severe side effects. Organoplatinum compounds are significantly less investigated than the analogous coordination compounds. We report here...

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Babak MV, Pfaffeneder-Kmen M, Meier-Menches SM, et al. Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action. Inorg Chem. 2018;57(5):2851-2864doi: 10.1021/acs.inorgchem.7b03210.
Babak, M. V., Pfaffeneder-Kmen, M., Meier-Menches, S. M., Legina, M. S., Theiner, S., Licona, C., Orvain, C., Hejl, M., Hanif, M., Jakupec, M. A., Keppler, B. K., Gaiddon, C., & Hartinger, C. G. (2018). Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action. Inorganic chemistry, 57(5), 2851-2864. https://doi.org/10.1021/acs.inorgchem.7b03210
Babak, Maria V, et al. "Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action." Inorganic chemistry vol. 57,5 (2018): 2851-2864. doi: https://doi.org/10.1021/acs.inorgchem.7b03210
Babak MV, Pfaffeneder-Kmen M, Meier-Menches SM, Legina MS, Theiner S, Licona C, Orvain C, Hejl M, Hanif M, Jakupec MA, Keppler BK, Gaiddon C, Hartinger CG. Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action. Inorg Chem. 2018 Mar 05;57(5):2851-2864. doi: 10.1021/acs.inorgchem.7b03210. Epub 2018 Feb 14. PMID: 29442506.
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