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Use of synthetic oligodeoxyribonucleotides and primed cDNA as probes for pea (Pisum sativum L.) RNA and genomic DNA sequences.

Plant molecular biology

Marta Evans I, Gatehouse JA, Lycett GW, Boulter D.
PMID: 24310302
Plant Mol Biol. 1984 Mar;3(2):73-81. doi: 10.1007/BF00040031.

Two oligonucleotide sequences were synthesised by a solid-phase phosphotriester method. One of these sequences, A was a copy of part of a characterised cDNA clone encoding the basic subunit of legumin, a seed storage protein of Pisum sativum L....

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Marta Evans I, Gatehouse JA, Lycett GW, et al. Use of synthetic oligodeoxyribonucleotides and primed cDNA as probes for pea (Pisum sativum L.) RNA and genomic DNA sequences. Plant Mol Biol. 1984;3(2):73-81doi: 10.1007/BF00040031.
Marta Evans, I., Gatehouse, J. A., Lycett, G. W., & Boulter, D. (1984). Use of synthetic oligodeoxyribonucleotides and primed cDNA as probes for pea (Pisum sativum L.) RNA and genomic DNA sequences. Plant molecular biology, 3(2), 73-81. https://doi.org/10.1007/BF00040031
Marta Evans, I, et al. "Use of synthetic oligodeoxyribonucleotides and primed cDNA as probes for pea (Pisum sativum L.) RNA and genomic DNA sequences." Plant molecular biology vol. 3,2 (1984): 73-81. doi: https://doi.org/10.1007/BF00040031
Marta Evans I, Gatehouse JA, Lycett GW, Boulter D. Use of synthetic oligodeoxyribonucleotides and primed cDNA as probes for pea (Pisum sativum L.) RNA and genomic DNA sequences. Plant Mol Biol. 1984 Mar;3(2):73-81. doi: 10.1007/BF00040031. PMID: 24310302.
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A critical assessment of the potential of short interfering RNA therapeutics.

Drug discovery today. Technologies

Stein CA, Rossi JJ.
PMID: 24981752
Drug Discov Today Technol. 2005;2(1):27-31. doi: 10.1016/j.ddtec.2005.05.013.

siRNA technology is now being extensively investigated both academically and commercially as a therapeutic modality because of its ability, at low concentration, to effectively downregulate the expression of target genes in tissue culture. However, the road to therapeutic siRNAs,...

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Stein CA, Rossi JJ. A critical assessment of the potential of short interfering RNA therapeutics. Drug Discov Today Technol. 2005;2(1):27-31doi: 10.1016/j.ddtec.2005.05.013.
Stein, C. A., & Rossi, J. J. (2005). A critical assessment of the potential of short interfering RNA therapeutics. Drug discovery today. Technologies, 2(1), 27-31. https://doi.org/10.1016/j.ddtec.2005.05.013
Stein, C A, and Rossi, J J. "A critical assessment of the potential of short interfering RNA therapeutics." Drug discovery today. Technologies vol. 2,1 (2005): 27-31. doi: https://doi.org/10.1016/j.ddtec.2005.05.013
Stein CA, Rossi JJ. A critical assessment of the potential of short interfering RNA therapeutics. Drug Discov Today Technol. 2005;2(1):27-31. doi: 10.1016/j.ddtec.2005.05.013. PMID: 24981752.
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Possible prebiotic condensation of mononucleotides by cyanamide.

Science (New York, N.Y.)

Ibanez JD, Kimball AP, Oro J.
PMID: 17770449
Science. 1971 Jul 30;173(3995):444-6. doi: 10.1126/science.173.3995.444.

The condensation of mononucleotides has been carried out in aqueous solution at neutral pH in the presence of cyanamide. Oligodeoxyribonucleotides up to five units have been formed when montmorillonite was present.

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Ibanez JD, Kimball AP, Oro J. Possible prebiotic condensation of mononucleotides by cyanamide. Science. 1971;173(3995):444-6doi: 10.1126/science.173.3995.444.
Ibanez, J. D., Kimball, A. P., & Oro, J. (1971). Possible prebiotic condensation of mononucleotides by cyanamide. Science (New York, N.Y.), 173(3995), 444-6. https://doi.org/10.1126/science.173.3995.444
Ibanez, J D, et al. "Possible prebiotic condensation of mononucleotides by cyanamide." Science (New York, N.Y.) vol. 173,3995 (1971): 444-6. doi: https://doi.org/10.1126/science.173.3995.444
Ibanez JD, Kimball AP, Oro J. Possible prebiotic condensation of mononucleotides by cyanamide. Science. 1971 Jul 30;173(3995):444-6. doi: 10.1126/science.173.3995.444. PMID: 17770449.
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Analysis of coherent heteroclustering of different dyes by use of threoninol nucleotides for comparison with the molecular exciton theory.

Chemistry (Weinheim an der Bergstrasse, Germany)

Fujii T, Kashida H, Asanuma H.
PMID: 19722239
Chemistry. 2009 Oct 05;15(39):10092-102. doi: 10.1002/chem.200900962.

To test the molecular exciton theory for heterodimeric chromophores, various heterodimers and clusters, in which two different dyes were stacked alternately, were prepared by hybridizing two oligodeoxyribonucleotides (ODNs), each of which tethered a different dye on D-threoninol at the...

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Fujii T, Kashida H, Asanuma H. Analysis of coherent heteroclustering of different dyes by use of threoninol nucleotides for comparison with the molecular exciton theory. Chemistry. 2009;15(39):10092-102doi: 10.1002/chem.200900962.
Fujii, T., Kashida, H., & Asanuma, H. (2009). Analysis of coherent heteroclustering of different dyes by use of threoninol nucleotides for comparison with the molecular exciton theory. Chemistry (Weinheim an der Bergstrasse, Germany), 15(39), 10092-102. https://doi.org/10.1002/chem.200900962
Fujii, Taiga, et al. "Analysis of coherent heteroclustering of different dyes by use of threoninol nucleotides for comparison with the molecular exciton theory." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 15,39 (2009): 10092-102. doi: https://doi.org/10.1002/chem.200900962
Fujii T, Kashida H, Asanuma H. Analysis of coherent heteroclustering of different dyes by use of threoninol nucleotides for comparison with the molecular exciton theory. Chemistry. 2009 Oct 05;15(39):10092-102. doi: 10.1002/chem.200900962. PMID: 19722239.
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Effective DNA inhibitors of cathepsin g by in vitro selection.

International journal of molecular sciences

Gatto B, Vianini E, Lucatello L, Sissi C, Moltrasio D, Pescador R, Porta R, Palumbo M.
PMID: 19325843
Int J Mol Sci. 2008 Jun;9(6):1008-23. doi: 10.3390/ijms9061008. Epub 2008 Jun 20.

Cathepsin G (CatG) is a chymotrypsin-like protease released upon degranulation of neutrophils. In several inflammatory and ischaemic diseases the impaired balance between CatG and its physiological inhibitors leads to tissue destruction and platelet aggregation. Inhibitors of CatG are suitable...

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Gatto B, Vianini E, Lucatello L, et al. Effective DNA inhibitors of cathepsin g by in vitro selection. Int J Mol Sci. 2008;9(6):1008-23doi: 10.3390/ijms9061008.
Gatto, B., Vianini, E., Lucatello, L., Sissi, C., Moltrasio, D., Pescador, R., Porta, R., & Palumbo, M. (2008). Effective DNA inhibitors of cathepsin g by in vitro selection. International journal of molecular sciences, 9(6), 1008-23. https://doi.org/10.3390/ijms9061008
Gatto, Barbara, et al. "Effective DNA inhibitors of cathepsin g by in vitro selection." International journal of molecular sciences vol. 9,6 (2008): 1008-23. doi: https://doi.org/10.3390/ijms9061008
Gatto B, Vianini E, Lucatello L, Sissi C, Moltrasio D, Pescador R, Porta R, Palumbo M. Effective DNA inhibitors of cathepsin g by in vitro selection. Int J Mol Sci. 2008 Jun;9(6):1008-23. doi: 10.3390/ijms9061008. Epub 2008 Jun 20. PMID: 19325843; PMCID: PMC2658781.
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Manual oligonucleotide synthesis using the phosphoramidite method.

Methods in molecular biology (Clifton, N.J.)

White HA.
PMID: 21424634
Methods Mol Biol. 1988;4:193-213. doi: 10.1385/0-89603-127-6:193.

Oligodeoxyribonucleotides may be synthesized on a solid support, which allows for the elongation of the chain without intermediate purifications. The exocyclic amino groups on cytosine and the purines are protected as the alkali-labile benzoyl or iso-butyryl amides. The 3'-OH...

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White HA. Manual oligonucleotide synthesis using the phosphoramidite method. Methods Mol Biol. 1988;4:193-213doi: 10.1385/0-89603-127-6:193.
White, H. A. (1988). Manual oligonucleotide synthesis using the phosphoramidite method. Methods in molecular biology (Clifton, N.J.), 4193-213. https://doi.org/10.1385/0-89603-127-6:193
White, H A. "Manual oligonucleotide synthesis using the phosphoramidite method." Methods in molecular biology (Clifton, N.J.) vol. 4 (1988): 193-213. doi: https://doi.org/10.1385/0-89603-127-6:193
White HA. Manual oligonucleotide synthesis using the phosphoramidite method. Methods Mol Biol. 1988;4:193-213. doi: 10.1385/0-89603-127-6:193. PMID: 21424634.
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7',5'-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy.

Nucleic acids research

Evéquoz D, Verhaart IEC, van de Vijver D, Renner W, Aartsma-Rus A, Leumann CJ.
PMID: 34850138
Nucleic Acids Res. 2021 Dec 02;49(21):12089-12105. doi: 10.1093/nar/gkab1097.

Antisense oligonucleotides are small pieces of modified DNA or RNA, which offer therapeutic potential for many diseases. We report on the synthesis of 7',5'-α-bc-DNA phosphoramidite building blocks, bearing the A, G, T and MeC nucleobases. Solid-phase synthesis was performed...

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Evéquoz D, Verhaart IEC, van de Vijver D, et al. 7',5'-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy. Nucleic Acids Res. 2021;49(21):12089-12105doi: 10.1093/nar/gkab1097.
Evéquoz, D., Verhaart, I. E. C., van de Vijver, D., Renner, W., Aartsma-Rus, A., & Leumann, C. J. (2021). 7',5'-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy. Nucleic acids research, 49(21), 12089-12105. https://doi.org/10.1093/nar/gkab1097
Evéquoz, Damien, et al. "7',5'-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy." Nucleic acids research vol. 49,21 (2021): 12089-12105. doi: https://doi.org/10.1093/nar/gkab1097
Evéquoz D, Verhaart IEC, van de Vijver D, Renner W, Aartsma-Rus A, Leumann CJ. 7',5'-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy. Nucleic Acids Res. 2021 Dec 02;49(21):12089-12105. doi: 10.1093/nar/gkab1097. PMID: 34850138; PMCID: PMC8643641.
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Synthetic Hexanucleotides as a Tool to Overcome Excessive Neutrophil Activation Caused by CpG-Containing Oligonucleotides.

Pathogens (Basel, Switzerland)

Golenkina EA, Galkina SI, Dolinnaya NG, Arifulin EA, Romanova YM, Sud'ina GF.
PMID: 33924760
Pathogens. 2021 Apr 28;10(5). doi: 10.3390/pathogens10050530.

Mimicking bacterial DNA, synthetic CpG-containing oligodeoxyribonucleotides (CpG-ODNs) have a powerful immunomodulatory potential. Their practical application is mainly associated with the production of vaccines, where they are used as adjuvants, as well as in local antimicrobial therapy. CpG-ODNs act on...

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Golenkina EA, Galkina SI, Dolinnaya NG, et al. Synthetic Hexanucleotides as a Tool to Overcome Excessive Neutrophil Activation Caused by CpG-Containing Oligonucleotides. Pathogens. 2021;10(5)doi: 10.3390/pathogens10050530.
Golenkina, E. A., Galkina, S. I., Dolinnaya, N. G., Arifulin, E. A., Romanova, Y. M., & Sud'ina, G. F. (2021). Synthetic Hexanucleotides as a Tool to Overcome Excessive Neutrophil Activation Caused by CpG-Containing Oligonucleotides. Pathogens (Basel, Switzerland), 10(5), . https://doi.org/10.3390/pathogens10050530
Golenkina, Ekaterina A, et al. "Synthetic Hexanucleotides as a Tool to Overcome Excessive Neutrophil Activation Caused by CpG-Containing Oligonucleotides." Pathogens (Basel, Switzerland) vol. 10,5 (2021). doi: https://doi.org/10.3390/pathogens10050530
Golenkina EA, Galkina SI, Dolinnaya NG, Arifulin EA, Romanova YM, Sud'ina GF. Synthetic Hexanucleotides as a Tool to Overcome Excessive Neutrophil Activation Caused by CpG-Containing Oligonucleotides. Pathogens. 2021 Apr 28;10(5). doi: 10.3390/pathogens10050530. PMID: 33924760; PMCID: PMC8146577.
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Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis.

Allergy, asthma & immunology research

Wee JH, Zhang YL, Rhee CS, Kim DY.
PMID: 27826963
Allergy Asthma Immunol Res. 2017 Jan;9(1):61-69. doi: 10.4168/aair.2017.9.1.61.

PURPOSE: It remains unknown whether local inhibition of Nuclear factor-kappa B (NF-κB) could have therapeutic value in the treatment of allergic rhinitis (AR). This study aimed to evaluate the effect of selective NF-κB inhibition using NF-κB decoy oligodeoxynucleotides (ODNs)...

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Wee JH, Zhang YL, Rhee CS, et al. Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis. Allergy Asthma Immunol Res. 2017;9(1):61-69doi: 10.4168/aair.2017.9.1.61.
Wee, J. H., Zhang, Y. L., Rhee, C. S., & Kim, D. Y. (2017). Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis. Allergy, asthma & immunology research, 9(1), 61-69. https://doi.org/10.4168/aair.2017.9.1.61
Wee, Jee Hye, et al. "Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis." Allergy, asthma & immunology research vol. 9,1 (2017): 61-69. doi: https://doi.org/10.4168/aair.2017.9.1.61
Wee JH, Zhang YL, Rhee CS, Kim DY. Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis. Allergy Asthma Immunol Res. 2017 Jan;9(1):61-69. doi: 10.4168/aair.2017.9.1.61. PMID: 27826963; PMCID: PMC5102837.
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Simultaneous rapid chemical synthesis of over one hundred oligonucleotides on a microscale.

The EMBO journal

Matthes HW, Zenke WM, Grundström T, Staub A, Wintzerith M, Chambon P.
PMID: 16453516
EMBO J. 1984 Apr;3(4):801-5.

An inexpensive, extremely rapid manual method for simultaneous synthesis of large numbers of oligodeoxyribonucleotides on 50 or 150 nanomole scale is described. The oligonucleotides are assembled in parallel by the phosphotriester method on small cellulose paper disks in a...

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Matthes HW, Zenke WM, Grundström T, et al. Simultaneous rapid chemical synthesis of over one hundred oligonucleotides on a microscale. EMBO J. 1984;3(4):801-5
Matthes, H. W., Zenke, W. M., Grundström, T., Staub, A., Wintzerith, M., & Chambon, P. (1984). Simultaneous rapid chemical synthesis of over one hundred oligonucleotides on a microscale. The EMBO journal, 3(4), 801-5.
Matthes, H W, et al. "Simultaneous rapid chemical synthesis of over one hundred oligonucleotides on a microscale." The EMBO journal vol. 3,4 (1984): 801-5.
Matthes HW, Zenke WM, Grundström T, Staub A, Wintzerith M, Chambon P. Simultaneous rapid chemical synthesis of over one hundred oligonucleotides on a microscale. EMBO J. 1984 Apr;3(4):801-5. PMID: 16453516; PMCID: PMC557430.
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Site-Specific Mutagenesis in Escherichia coli by Bulky Exocyclic Amino-Substituted Guanine and Adenine Derivatives in Double-Stranded or Gapped Plasmids.

Cancer research and treatment

Moon KY.
PMID: 26680918
Cancer Res Treat. 2003 Feb;35(1):75-80. doi: 10.4143/crt.2003.35.1.75.

PURPOSE: 7-Bromomethylbenz[alpha]anthracene is a known mutagen and carcinogen. The mutagenic potency of its two major DNA adducts, i.e., N2-(benz[alpha]anthracen-7-ylmethyl)-2'-deoxyguanosine (b[alpha]a2G) and N6-(benz[alpha]anthracen-7-ylmethyl)-2'-deoxyadenosine (b[alpha]a6A), as well as the simpler benzylated analogs, N2-benzyl-2'-deoxyguanosine (bn2G) and N6-benzyl-2'-deoxyadenosine (bn6A), were determined in E....

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Moon KY. Site-Specific Mutagenesis in Escherichia coli by Bulky Exocyclic Amino-Substituted Guanine and Adenine Derivatives in Double-Stranded or Gapped Plasmids. Cancer Res Treat. 2003;35(1):75-80doi: 10.4143/crt.2003.35.1.75.
Moon, K. Y. (2003). Site-Specific Mutagenesis in Escherichia coli by Bulky Exocyclic Amino-Substituted Guanine and Adenine Derivatives in Double-Stranded or Gapped Plasmids. Cancer research and treatment, 35(1), 75-80. https://doi.org/10.4143/crt.2003.35.1.75
Moon, Ki Young. "Site-Specific Mutagenesis in Escherichia coli by Bulky Exocyclic Amino-Substituted Guanine and Adenine Derivatives in Double-Stranded or Gapped Plasmids." Cancer research and treatment vol. 35,1 (2003): 75-80. doi: https://doi.org/10.4143/crt.2003.35.1.75
Moon KY. Site-Specific Mutagenesis in Escherichia coli by Bulky Exocyclic Amino-Substituted Guanine and Adenine Derivatives in Double-Stranded or Gapped Plasmids. Cancer Res Treat. 2003 Feb;35(1):75-80. doi: 10.4143/crt.2003.35.1.75. PMID: 26680918.
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Nuclear factor-kappa B decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres promote periodontal tissue healing after tooth replantation in rats.

Journal of periodontology

Li K, Ishida Y, Hatano-Sato K, Ongprakobkul N, Hosomichi J, Usumi-Fujita R, Kaneko S, Yamaguchi H, Ono T.
PMID: 34319612
J Periodontol. 2021 Jul 28; doi: 10.1002/JPER.21-0134. Epub 2021 Jul 28.

BACKGROUND: Excessive inflammation in the periodontal tissue after tooth replantation can lead to inflammatory root resorption and interrupt periodontal tissue regeneration. We tested the hypothesis that nuclear factor-κB decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres (NF-PLGA) inhibit excessive inflammation and...

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Li K, Ishida Y, Hatano-Sato K, et al. Nuclear factor-kappa B decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres promote periodontal tissue healing after tooth replantation in rats. J Periodontol. 2021;doi: 10.1002/JPER.21-0134.
Li, K., Ishida, Y., Hatano-Sato, K., Ongprakobkul, N., Hosomichi, J., Usumi-Fujita, R., Kaneko, S., Yamaguchi, H., & Ono, T. (2021). Nuclear factor-kappa B decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres promote periodontal tissue healing after tooth replantation in rats. Journal of periodontology, . https://doi.org/10.1002/JPER.21-0134
Li, Kai, et al. "Nuclear factor-kappa B decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres promote periodontal tissue healing after tooth replantation in rats." Journal of periodontology vol. (2021). doi: https://doi.org/10.1002/JPER.21-0134
Li K, Ishida Y, Hatano-Sato K, Ongprakobkul N, Hosomichi J, Usumi-Fujita R, Kaneko S, Yamaguchi H, Ono T. Nuclear factor-kappa B decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres promote periodontal tissue healing after tooth replantation in rats. J Periodontol. 2021 Jul 28; doi: 10.1002/JPER.21-0134. Epub 2021 Jul 28. PMID: 34319612.
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