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Showing 1 to 12 of 13722 entries
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Males are from Mars, and females are from Venus: sex-specific fetal brain gene expression signatures in a mouse model of maternal diet-induced obesity

STEM and males

Edlow AG, Sverdlov D.
GSID: gsSz55-ceR8J
AG Edlow, F Guedj, JLA Pennings, D Sverdlov… - American journal of …, 2016 - Elsevier

… gene expression changes in males v females in the setting of maternal obesity and dietary change. Within these DEGs, a block of 37 differentially expressed stem-loop microRNAs (…

miR-132 mediates the integration of newborn neurons into the adult dentate gyrus

adult

Luikart BW.
GSID: L127cv7LRJsJ
BW Luikart, ASL Bensen, EK Washburn, JV Perederiy… - PloS one, 2011 - journals.plos.org

Neuronal activity enhances the elaboration of newborn neurons as they integrate into the synaptic circuitry of the adult brain. The role microRNAs play in the transduction of neuronal …

Molecular Mechanisms and Applications of a Reserpine-Induced Rodent Model

Louis Stokes Alliances for Minority Participation AND Program Evaluation

[No authors listed]
GSID: fomOK-r4k_wJ
T Hedgecock, A Phillips, B Ludrick, T Golden… - SSR Institute of …, 2019 - par.nsf.gov

Host-induced gene silencing (HIGS) refers to the silencing of genes in pathogens and pests by expressing homologous double-stranded RNAs (dsRNA) or artificial microRNAs (amiRNAs) in the host plant. The discovery of such trans-kingdom RNA silencing has enabled the development...

Endogenous siRNA and miRNA targets identified by sequencing of the Arabidopsis degradome

pipeline programs

Addo-Quaye C, Axtell MJ, Bartel DP, Eshoo TW.
GSID: DGXfo6qJeVsJ
C Addo-Quaye, TW Eshoo, DP Bartel, MJ Axtell - Current Biology, 2008 - Elsevier

MicroRNAs (miRNAs) regulate the expression of target mRNAs in plants and animals [1]. Plant miRNA targets have been predicted on the basis of their extensive and often …

Evolution of microRNAs and the diversification of species

STEM and diversification

Streelman JT, Yi SV.
GSID: FUjoh09SNAYJ
YHE Loh, SV Yi, JT Streelman - Genome biology and evolution, 2011 - academic.oup.com

… (A) An example of predicted stem–loop secondary structure for a cichlid miRNA (lfu-mir-199-… for the loop region, and gray for the stem region excluding the mature miRNA. Vertical bars …

Altered microRNAs expression levels of sperm and seminal plasma in patients with infertile ejaculates compared with normozoospermic males

STEM and males

Mokánszki A.
GSID: 66l8BWB7iFoJ
A Mokánszki, Z Molnár, E Varga Tóthné, B Bodnár… - Human …, 2020 - Taylor & Francis

… and three were downregulated in infertile males compared to men with normozoospermic … be used as non-invasive biomarkers to diagnose males with impaired sperm production. …

Global identification of microRNA–target RNA pairs by parallel analysis of RNA ends

pipeline programs

Jeong DH, Pillay M.
GSID: tjsdBCWHG6AJ
MA German, M Pillay, DH Jeong, A Hetawal… - Nature …, 2008 - nature.com

MicroRNAs (miRNAs) are important regulatory molecules in most eukaryotes and identification of their target mRNAs is essential for their functional analysis. Whereas …

Regulation of miRNA 219 and miRNA Clusters 338 and 17-92 in Oligodendrocytes.

Frontiers in genetics

de Faria O, Cui QL, Bin JM, Bull SJ, Kennedy TE, Bar-Or A, Antel JP, Colman DR, Dhaunchak AS.
PMID: 22470405
Front Genet. 2012 Mar 28;3:46. doi: 10.3389/fgene.2012.00046. eCollection 2012.

MicroRNAs (miRs) regulate diverse molecular and cellular processes including oligodendrocyte (OL) precursor cell (OPC) proliferation and differentiation in rodents. However, the role of miRs in human OPCs is poorly understood. To identify miRs that may regulate these processes in...

Molecular pathways associated with aggressiveness of papillary thyroid cancer.

Current genomics

Benvenga S, Koch CA.
PMID: 24955023
Curr Genomics. 2014 Jun;15(3):162-70. doi: 10.2174/1389202915999140404100958.

The most common thyroid malignancy is papillary thyroid cancer (PTC). Mortality rates from PTC mainly depend on its aggressiveness. Geno- and phenotyping of aggressive PTC has advanced our understanding of treatment failures and of potential future therapies. Unraveling molecular...

Current understanding of the role of microRNAs in spinocerebellar ataxias.

Cerebellum & ataxias

Koscianska E, Krzyzosiak WJ.
PMID: 26331031
Cerebellum Ataxias. 2014 Aug 07;1:7. doi: 10.1186/2053-8871-1-7. eCollection 2014.

The number of studies highlighting the role of microRNAs (miRNAs) in human physiology and diseases is growing, but many miRNA-driven regulatory mechanisms remain elusive. A proper understanding of the exact functions of individual miRNAs and their interaction with specific...

Small RNA and Transcriptome Sequencing Reveal a Potential miRNA-Mediated Interaction Network That Functions during Somatic Embryogenesis in .

Frontiers in plant science

Zhang J, Xue B, Gai M, Song S, Jia N, Sun H.
PMID: 28473835
Front Plant Sci. 2017 Apr 20;8:566. doi: 10.3389/fpls.2017.00566. eCollection 2017.

Plant somatic embryos are widely used in the fields of germplasm conservation, breeding for genetic engineering and artificial seed production. MicroRNAs (miRNAs) play pivotal roles in somatic embryogenesis (SE) regulation. However, their regulatory roles during various stages of SE...

The Biochemical Cascades of the Human Pancreatic .

Journal of bioanalysis & biomedicine

Kim JW, Luo JZ, Luo L.
PMID: 28503255
J Bioanal Biomed. 2015 Dec;7(6). doi: 10.4172/1948-593X.1000e133. Epub 2015 Dec 11.

Diabetes mellitus is a disease that poses a burden to the health care system due to its prevalence and chronic nature. Understanding β cell pathophysiology may lead to future therapeutic options for diabetes mellitus type 1 and 2. MicroRNAs...

Showing 1 to 12 of 13722 entries