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Showing 1 to 12 of 507 entries
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Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro.

Chinese medicine

Ouyang DS, Huang WH, Chen D, Zhang W, Tan ZR, Peng JB, Wang YC, Guo Y, Hu DL, Xiao J, Chen Y.
PMID: 27006687
Chin Med. 2016 Mar 22;11:11. doi: 10.1186/s13020-016-0083-z. eCollection 2016.

BACKGROUND: Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA for treating cardiovascular disorders. The roles of cytochrome P450 enzymes (CYPs) in the metabolism of STS have remained unclear. This study aims to screen the main...

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Ouyang DS, Huang WH, Chen D, et al. Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro. Chin Med. 2016;11:11doi: 10.1186/s13020-016-0083-z.
Ouyang, D. S., Huang, W. H., Chen, D., Zhang, W., Tan, Z. R., Peng, J. B., Wang, Y. C., Guo, Y., Hu, D. L., Xiao, J., & Chen, Y. (2016). Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro. Chinese medicine, 1111. https://doi.org/10.1186/s13020-016-0083-z
Ouyang, Dong-Sheng, et al. "Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro." Chinese medicine vol. 11 (2016): 11. doi: https://doi.org/10.1186/s13020-016-0083-z
Ouyang DS, Huang WH, Chen D, Zhang W, Tan ZR, Peng JB, Wang YC, Guo Y, Hu DL, Xiao J, Chen Y. Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro. Chin Med. 2016 Mar 22;11:11. doi: 10.1186/s13020-016-0083-z. eCollection 2016. PMID: 27006687; PMCID: PMC4802617.
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Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures.

Heart international

Vinik AI, Bloom HL, Colombo J.
PMID: 27004091
Heart Int. 2014 Aug 22;9(1):7-14. eCollection 2014.

BACKGROUND: Cardiovascular autonomic neuropathy (CAN) is recognized as a significant health risk. Specific and sensitive measures of CAN are needed for early identification and treatment to avoid complications, preferably in the preclinical state.OBJECTIVES: In this first of two articles,...

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Vinik AI, Bloom HL, Colombo J. Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures. Heart Int. 2014;9(1):7-14
Vinik, A. I., Bloom, H. L., & Colombo, J. (2014). Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures. Heart international, 9(1), 7-14.
Vinik, Aaron I, et al. "Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures." Heart international vol. 9,1 (2014): 7-14.
Vinik AI, Bloom HL, Colombo J. Differential effects of adrenergic antagonists (Carvedilol vs Metoprolol) on parasympathetic and sympathetic activity: a comparison of measures. Heart Int. 2014 Aug 22;9(1):7-14. eCollection 2014. PMID: 27004091; PMCID: PMC4774948.
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Takotsubo cardiomyopathy in an 81-year-old woman after injection of bone cement during hemiarthroplasty: An orthogeriatric case report.

International journal of surgery case reports

Mazzola P, Picone D, Anzuini A, Corsi M, Bellelli G, Annoni G.
PMID: 26688511
Int J Surg Case Rep. 2016;18:37-41. doi: 10.1016/j.ijscr.2015.11.025. Epub 2015 Nov 27.

INTRODUCTION: Takotsubo cardiomyopathy is a syndrome characterized by transient cardiac ischemia-like symptoms, such as chest pain, increase of myocardial necrosis markers, electrocardiographic changes, and temporary left ventricular apical ballooning without significant coronary artery disease, often triggered by a particularly...

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Mazzola P, Picone D, Anzuini A, et al. Takotsubo cardiomyopathy in an 81-year-old woman after injection of bone cement during hemiarthroplasty: An orthogeriatric case report. Int J Surg Case Rep. 2015;18:37-41doi: 10.1016/j.ijscr.2015.11.025.
Mazzola, P., Picone, D., Anzuini, A., Corsi, M., Bellelli, G., & Annoni, G. (2016). Takotsubo cardiomyopathy in an 81-year-old woman after injection of bone cement during hemiarthroplasty: An orthogeriatric case report. International journal of surgery case reports, 1837-41. https://doi.org/10.1016/j.ijscr.2015.11.025
Mazzola, Paolo, et al. "Takotsubo cardiomyopathy in an 81-year-old woman after injection of bone cement during hemiarthroplasty: An orthogeriatric case report." International journal of surgery case reports vol. 18 (2016): 37-41. doi: https://doi.org/10.1016/j.ijscr.2015.11.025
Mazzola P, Picone D, Anzuini A, Corsi M, Bellelli G, Annoni G. Takotsubo cardiomyopathy in an 81-year-old woman after injection of bone cement during hemiarthroplasty: An orthogeriatric case report. Int J Surg Case Rep. 2016;18:37-41. doi: 10.1016/j.ijscr.2015.11.025. Epub 2015 Nov 27. PMID: 26688511; PMCID: PMC4701876.
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A double-blind crossover comparison of pindolol, metoprolol, atenolol and labetalol in mild to moderate hypertension.

British journal of clinical pharmacology

McNeil JJ, Louis WJ.
PMID: 26635160
Br J Clin Pharmacol. 1979 Apr;8:163S-6S. doi: 10.1111/j.1365-2125.1979.tb04774.x.

1 This study was designed to compare in a double-blind randomized crossover trial, atenolol, labetalol, metoprolol and pindolol. Considerable differences in dose (atenolol 138 +/- 13 mg daily; labetalol 308 +/- 34 mg daily; metoprolol 234 +/- 22 mg...

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McNeil JJ, Louis WJ. A double-blind crossover comparison of pindolol, metoprolol, atenolol and labetalol in mild to moderate hypertension. Br J Clin Pharmacol. 1979;8:163S-6Sdoi: 10.1111/j.1365-2125.1979.tb04774.x.
McNeil, J. J., & Louis, W. J. (1979). A double-blind crossover comparison of pindolol, metoprolol, atenolol and labetalol in mild to moderate hypertension. British journal of clinical pharmacology, 8163S-6S. https://doi.org/10.1111/j.1365-2125.1979.tb04774.x
McNeil, J J, and Louis, W J. "A double-blind crossover comparison of pindolol, metoprolol, atenolol and labetalol in mild to moderate hypertension." British journal of clinical pharmacology vol. 8 (1979): 163S-6S. doi: https://doi.org/10.1111/j.1365-2125.1979.tb04774.x
McNeil JJ, Louis WJ. A double-blind crossover comparison of pindolol, metoprolol, atenolol and labetalol in mild to moderate hypertension. Br J Clin Pharmacol. 1979 Apr;8:163S-6S. doi: 10.1111/j.1365-2125.1979.tb04774.x. PMID: 26635160.
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Assessment of drug-drug interactions in hypertensive patients at a superspeciality hospital.

Avicenna journal of medicine

Sivva D, Mateti UV, Neerati VM, Thiruthopu NS, Martha S.
PMID: 25878964
Avicenna J Med. 2015 Apr-Jun;5(2):29-35. doi: 10.4103/2231-0770.154194.

OBJECTIVE: The objective of the study was to assess the incidence and pattern of drug-drug interactions (DDIs) in hypertensive patients by using Micromedex and Medscape databases.MATERIALS AND METHODS: A prospective observational study was carried out in a superspeciality hospital...

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Sivva D, Mateti UV, Neerati VM, et al. Assessment of drug-drug interactions in hypertensive patients at a superspeciality hospital. Avicenna J Med. 2015;5(2):29-35doi: 10.4103/2231-0770.154194.
Sivva, D., Mateti, U. V., Neerati, V. M., Thiruthopu, N. S., & Martha, S. (2015). Assessment of drug-drug interactions in hypertensive patients at a superspeciality hospital. Avicenna journal of medicine, 5(2), 29-35. https://doi.org/10.4103/2231-0770.154194
Sivva, Divya, et al. "Assessment of drug-drug interactions in hypertensive patients at a superspeciality hospital." Avicenna journal of medicine vol. 5,2 (2015): 29-35. doi: https://doi.org/10.4103/2231-0770.154194
Sivva D, Mateti UV, Neerati VM, Thiruthopu NS, Martha S. Assessment of drug-drug interactions in hypertensive patients at a superspeciality hospital. Avicenna J Med. 2015 Apr-Jun;5(2):29-35. doi: 10.4103/2231-0770.154194. PMID: 25878964; PMCID: PMC4394569.
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Functional Effects of Alagebrium (ALT-711)-Isolated Rat Carotid Artery.

The Eurasian journal of medicine

Toprak C, Sirmagul B, Yigitaslan S.
PMID: 29123442
Eurasian J Med. 2017 Oct;49(3):188-192. doi: 10.5152/eurasianjmed.2017.17046.

OBJECTIVE: In our study, the effects of glycosylated protein cross-link breaker, alagebrium was investigated on isolated rat carotid artery using myography. Alagebrium showed vasodilator effect on carotid artery rings; particularly, this effect was significantly increased in endothelium-intact rings.MATERIALS AND...

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Toprak C, Sirmagul B, Yigitaslan S. Functional Effects of Alagebrium (ALT-711)-Isolated Rat Carotid Artery. Eurasian J Med. 2017;49(3):188-192doi: 10.5152/eurasianjmed.2017.17046.
Toprak, C., Sirmagul, B., & Yigitaslan, S. (2017). Functional Effects of Alagebrium (ALT-711)-Isolated Rat Carotid Artery. The Eurasian journal of medicine, 49(3), 188-192. https://doi.org/10.5152/eurasianjmed.2017.17046
Toprak, Cigdem, et al. "Functional Effects of Alagebrium (ALT-711)-Isolated Rat Carotid Artery." The Eurasian journal of medicine vol. 49,3 (2017): 188-192. doi: https://doi.org/10.5152/eurasianjmed.2017.17046
Toprak C, Sirmagul B, Yigitaslan S. Functional Effects of Alagebrium (ALT-711)-Isolated Rat Carotid Artery. Eurasian J Med. 2017 Oct;49(3):188-192. doi: 10.5152/eurasianjmed.2017.17046. PMID: 29123442; PMCID: PMC5665628.
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A computational procedure for assessing the dynamic performance of diffusion-controlled transdermal delivery devices.

Pharmaceutics

Simon L.
PMID: 24310592
Pharmaceutics. 2011 Aug 11;3(3):485-96. doi: 10.3390/pharmaceutics3030485.

The dynamic performances of two different controlled-release systems were analyzed. In a reservoir-type drug-delivery patch, the transdermal flux is influenced by the properties of the membrane. A constant thermodynamic drug activity is preserved in the donor compartment. Monolithic matrices...

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Simon L. A computational procedure for assessing the dynamic performance of diffusion-controlled transdermal delivery devices. Pharmaceutics. 2011;3(3):485-96doi: 10.3390/pharmaceutics3030485.
Simon, L. (2011). A computational procedure for assessing the dynamic performance of diffusion-controlled transdermal delivery devices. Pharmaceutics, 3(3), 485-96. https://doi.org/10.3390/pharmaceutics3030485
Simon, Laurent. "A computational procedure for assessing the dynamic performance of diffusion-controlled transdermal delivery devices." Pharmaceutics vol. 3,3 (2011): 485-96. doi: https://doi.org/10.3390/pharmaceutics3030485
Simon L. A computational procedure for assessing the dynamic performance of diffusion-controlled transdermal delivery devices. Pharmaceutics. 2011 Aug 11;3(3):485-96. doi: 10.3390/pharmaceutics3030485. PMID: 24310592; PMCID: PMC3857078.
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Is it time to replace propranolol with carvedilol for portal hypertension?.

World journal of gastrointestinal endoscopy

Abid S, Ali S, Baig MA, Waheed AA.
PMID: 25992192
World J Gastrointest Endosc. 2015 May 16;7(5):532-9. doi: 10.4253/wjge.v7.i5.532.

Beta-adrenergic receptor antagonists (β-blockers) have been well established for use in portal hypertension for more than three decades. Different Non-selective β-blockers like propranolol, nadolol, timolol, atenolol, metoprolol and carvedilol have been in clinical practice in patients with cirrhosis. Carvedilol...

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Abid S, Ali S, Baig MA, et al. Is it time to replace propranolol with carvedilol for portal hypertension?. World J Gastrointest Endosc. 2015;7(5):532-9doi: 10.4253/wjge.v7.i5.532.
Abid, S., Ali, S., Baig, M. A., & Waheed, A. A. (2015). Is it time to replace propranolol with carvedilol for portal hypertension?. World journal of gastrointestinal endoscopy, 7(5), 532-9. https://doi.org/10.4253/wjge.v7.i5.532
Abid, Shahab, et al. "Is it time to replace propranolol with carvedilol for portal hypertension?." World journal of gastrointestinal endoscopy vol. 7,5 (2015): 532-9. doi: https://doi.org/10.4253/wjge.v7.i5.532
Abid S, Ali S, Baig MA, Waheed AA. Is it time to replace propranolol with carvedilol for portal hypertension?. World J Gastrointest Endosc. 2015 May 16;7(5):532-9. doi: 10.4253/wjge.v7.i5.532. PMID: 25992192; PMCID: PMC4436921.
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Metoprolol-induced Severe Liver Injury and Successful Management with Therapeutic Plasma Exchange.

Cureus

Philips C, Paramaguru R, Mahadevan P, Ravindranath J, Augustine P.
PMID: 28589058
Cureus. 2017 May 02;9(5):e1209. doi: 10.7759/cureus.1209.

Liver injury caused by metoprolol is very rare with current reports limited to an isolated elevation in transaminases. We report the first case of severe icteric liver injury leading to hepatic encephalopathy secondary to metoprolol use in a patient...

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Philips C, Paramaguru R, Mahadevan P, et al. Metoprolol-induced Severe Liver Injury and Successful Management with Therapeutic Plasma Exchange. Cureus. 2017;9(5):e1209doi: 10.7759/cureus.1209.
Philips, C., Paramaguru, R., Mahadevan, P., Ravindranath, J., & Augustine, P. (2017). Metoprolol-induced Severe Liver Injury and Successful Management with Therapeutic Plasma Exchange. Cureus, 9(5), e1209. https://doi.org/10.7759/cureus.1209
Philips, Cyriac, et al. "Metoprolol-induced Severe Liver Injury and Successful Management with Therapeutic Plasma Exchange." Cureus vol. 9,5 (2017): e1209. doi: https://doi.org/10.7759/cureus.1209
Philips C, Paramaguru R, Mahadevan P, Ravindranath J, Augustine P. Metoprolol-induced Severe Liver Injury and Successful Management with Therapeutic Plasma Exchange. Cureus. 2017 May 02;9(5):e1209. doi: 10.7759/cureus.1209. PMID: 28589058; PMCID: PMC5453740.
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An alternative approach to risk rank chemicals on the threat they pose to the aquatic environment.

The Science of the total environment

Johnson AC, Donnachie RL, Sumpter JP, Jürgens MD, Moeckel C, Pereira MG.
PMID: 28531948
Sci Total Environ. 2017 Dec 01;599:1372-1381. doi: 10.1016/j.scitotenv.2017.05.039. Epub 2017 May 17.

This work presents a new and unbiased method of risk ranking chemicals based on the threat they pose to the aquatic environment. The study ranked 12 metals, 23 pesticides, 11 other persistent organic pollutants (POPs), 13 pharmaceuticals, 10 surfactants...

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Johnson AC, Donnachie RL, Sumpter JP, et al. An alternative approach to risk rank chemicals on the threat they pose to the aquatic environment. Sci Total Environ. 2017;599:1372-1381doi: 10.1016/j.scitotenv.2017.05.039.
Johnson, A. C., Donnachie, R. L., Sumpter, J. P., Jürgens, M. D., Moeckel, C., & Pereira, M. G. (2017). An alternative approach to risk rank chemicals on the threat they pose to the aquatic environment. The Science of the total environment, 5991372-1381. https://doi.org/10.1016/j.scitotenv.2017.05.039
Johnson, Andrew C, et al. "An alternative approach to risk rank chemicals on the threat they pose to the aquatic environment." The Science of the total environment vol. 599 (2017): 1372-1381. doi: https://doi.org/10.1016/j.scitotenv.2017.05.039
Johnson AC, Donnachie RL, Sumpter JP, Jürgens MD, Moeckel C, Pereira MG. An alternative approach to risk rank chemicals on the threat they pose to the aquatic environment. Sci Total Environ. 2017 Dec 01;599:1372-1381. doi: 10.1016/j.scitotenv.2017.05.039. Epub 2017 May 17. PMID: 28531948.
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Relationship between cytochrome P450 polymorphisms and prescribed medication in elderly haemodialysis patients.

SpringerPlus

Parker K, Aasebø W, Haslemo T, Stavem K.
PMID: 27066364
Springerplus. 2016 Mar 22;5:350. doi: 10.1186/s40064-016-1986-y. eCollection 2016.

BACKGROUND: Elderly patients on haemodialysis have a high prevalence of polypharmacy and are at risk of drug-related complications. More than 80 % of all prescribed drugs are metabolized by the cytochrome P450 (CYP) enzyme system. The aims of this...

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Parker K, Aasebø W, Haslemo T, et al. Relationship between cytochrome P450 polymorphisms and prescribed medication in elderly haemodialysis patients. Springerplus. 2016;5:350doi: 10.1186/s40064-016-1986-y.
Parker, K., Aasebø, W., Haslemo, T., & Stavem, K. (2016). Relationship between cytochrome P450 polymorphisms and prescribed medication in elderly haemodialysis patients. SpringerPlus, 5350. https://doi.org/10.1186/s40064-016-1986-y
Parker, Krystina, et al. "Relationship between cytochrome P450 polymorphisms and prescribed medication in elderly haemodialysis patients." SpringerPlus vol. 5 (2016): 350. doi: https://doi.org/10.1186/s40064-016-1986-y
Parker K, Aasebø W, Haslemo T, Stavem K. Relationship between cytochrome P450 polymorphisms and prescribed medication in elderly haemodialysis patients. Springerplus. 2016 Mar 22;5:350. doi: 10.1186/s40064-016-1986-y. eCollection 2016. PMID: 27066364; PMCID: PMC4801827.
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Development of a sustained-release microcapsule for delivery of metoprolol succinate.

Experimental and therapeutic medicine

Song L, He S, Ping Q.
PMID: 28565860
Exp Ther Med. 2017 May;13(5):2435-2441. doi: 10.3892/etm.2017.4247. Epub 2017 Mar 21.

Sustained-release (SR) formulations of metoprolol succinate (MS) may minimize fluctuations in plasma concentration and decrease the resulting adverse events. The aim of the present study was to optimize the loading capacity of microcapsules and the SR of MS. A...

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Song L, He S, Ping Q. Development of a sustained-release microcapsule for delivery of metoprolol succinate. Exp Ther Med. 2017;13(5):2435-2441doi: 10.3892/etm.2017.4247.
Song, L., He, S., & Ping, Q. (2017). Development of a sustained-release microcapsule for delivery of metoprolol succinate. Experimental and therapeutic medicine, 13(5), 2435-2441. https://doi.org/10.3892/etm.2017.4247
Song, Li, et al. "Development of a sustained-release microcapsule for delivery of metoprolol succinate." Experimental and therapeutic medicine vol. 13,5 (2017): 2435-2441. doi: https://doi.org/10.3892/etm.2017.4247
Song L, He S, Ping Q. Development of a sustained-release microcapsule for delivery of metoprolol succinate. Exp Ther Med. 2017 May;13(5):2435-2441. doi: 10.3892/etm.2017.4247. Epub 2017 Mar 21. PMID: 28565860; PMCID: PMC5443309.
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Showing 1 to 12 of 507 entries