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Showing 1 to 12 of 224 entries
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The Potential Use of Methotrexate in the Treatment of Cutaneous Leishmaniasis: In Vitro Assays against Sensitive and Meglumine Antimoniate-resistant Strains of .

Iranian journal of parasitology

Mahmoudvand H, Kheirandish F, Mirbadie SR, Kayedi MH, Rezaei Riabi T, Ghasemi AA, Bamorovat M, Sharifi I.
PMID: 28979343
Iran J Parasitol. 2017 Jul-Sep;12(3):339-347.

BACKGROUND: The present study aimed to evaluate the effect of methotrexate (MTX) alone and in combination with meglumine antimoniate (MA, Glucantime) against sensitive and MA-resistant METHODS: The present study was carried out in 2014 in Leishmaniasis Research Center at...

First Report on Infant Acute Urticaria after Mother's Parenteral Use of Meglumine Antimoniate (Glucantime): A Case Report.

Iranian journal of public health

Mozafari O, Shorofi SA, Yousefi SS.
PMID: 27957467
Iran J Public Health. 2016 Sep;45(9):1217-1219.

Pentavalent antimonials are still the first drug of choice for the treatment of cutaneous leishmaniasis (CL). Like other treatments, they can cause adverse reactions including musculoskeletal pain, gastrointestinal disturbances, and mild to moderate headaches. In this paper, we report...

Effects of flunixin meglumine on experimental tendon wound healing: A histopathological and mechanical study in rabbits.

Veterinary research forum : an international quarterly journal

Behfar M, Hobbenaghi R, Sarrafzadeh-Rezaei F.
PMID: 25568677
Vet Res Forum. 2013;4(4):233-8.

Tendons are frequently targets of injury in sports and work. Whether nonsteroidal anti-inflammatory drugs (NSAIDs) have beneficial effects on tendon healing is still a matter of debate. This study was conducted to evaluate effects of flunixin meglumine (FM) on...

Localized Bullous Eruption Away From Injection Site, Caused by Intramuscular Meglumine Antimoniate Administration.

The Annals of pharmacotherapy

Ben Salem C, Slim R, Fathallah N, Sriha B, Belajouza C.
PMID: 27048189
Ann Pharmacother. 2016 Jun;50(6):517-8. doi: 10.1177/1060028016641131. Epub 2016 Apr 05.

No abstract available.

P-glycoprotein A Gene Expression in Glucantime-Resistant and Sensitive Leishmania major (MRHO/IR/75/ER).

Iranian journal of parasitology

Soleimanifard S, Arjmand R, Saberi S, Khamesipour A, Kazemi M, Salehi M, Akbari M, Hejazi S.
PMID: 25678928
Iran J Parasitol. 2014 Sep;9(3):423-8.

BACKGROUND: Leishmaniasis is a parasitic disease caused by different species of Leishmania parasites with a wide range of clinical manifestations. Antimonial compounds such as meglumine antimoniate (glucantime) are the first line drugs for the treatment of leishmaniasis. However, according...

Comparison of Proteome Profiling of Two Sensitive and Resistant Field Iranian Isolates of Leishmania major to Glucantime® by 2- Dimensional Electrophoresis.

Iranian journal of parasitology

Zarean M, Maraghi S, Hajjaran H, Mohebali M, Feiz-Hadad MH, Assarehzadegan MA.
PMID: 25904942
Iran J Parasitol. 2015 Jan-Mar;10(1):19-29.

BACKGROUND: In this study, two-dimensional gel electrophoresis (2-DE) method was applied to determine and compare the protein spots expressed in the two field isolates of Leishmania major and recovered from the patients who were clinically sensitive and resistant to...

Nephrotoxicity in dogs associated with methoxyflurane anesthesia and flunixin meglumine analgesia.

The Canadian veterinary journal = La revue veterinaire canadienne

Mathews KA, Doherty T, Dyson DH, Wilcock B, Valliant A.
PMID: 17423691
Can Vet J. 1990 Nov;31(11):766-71.

Uremia unexpectedly developed in five dogs 24 hours after undergoing thoracotomy in a student laboratory. In all dogs general anesthesia had been maintained with methoxyflurane, muscle relaxation had been induced with gallamine, and each dog received a single intravenous...

Comparison of oral zinc sulfate with systemic meglumine antimoniate in the treatment of cutaneous leishmaniasis.

Dermatology research and practice

Yazdanpanah MJ, Banihashemi M, Pezeshkpoor F, Khajedaluee M, Famili S, Tavakoli Rodi I, Yousefzadeh H.
PMID: 21747837
Dermatol Res Pract. 2011;2011:269515. doi: 10.1155/2011/269515. Epub 2011 Jul 06.

The purpose of this study was to investigate comparison between oral zinc sulfate and meglumine antimoniate in the treatment of cutaneous leishmaniasis (CL). So 100 patients with CL were included and randomly divided into two groups. The first group...

Treatment of cutaneous lesion of 20 years' duration caused by leishmanization.

Indian journal of dermatology

Khamesipour A, Abbasi A, Firooz A, Mohammadi AM, Eskandari SE, Jaafari MR.
PMID: 22615509
Indian J Dermatol. 2012 Mar;57(2):123-5. doi: 10.4103/0019-5154.94280.

The inoculation of live Leishmania (L.) major to produce a single lesion is called leishmanization (LZ). LZ lesion upon cure prevents further natural infection which might be multiple lesions on unwanted sites such as face. Cutaneous leishmaniasis (CL) usually...

Antileishmanial Activity of .

Iranian journal of parasitology

Shokri A, Saeedi M, Fakhar M, Morteza-Semnani K, Keighobadi M, Hosseini Teshnizi S, Kelidari HR, Sadjadi S.
PMID: 29317888
Iran J Parasitol. 2017 Oct-Dec;12(4):622-631.

BACKGROUND: The aim of present study was to evaluate antileishmanial effects of METHODS: The present study was performed in Leishmaniasis Reference Lab at Mazandaran University of Medical Sciences, Iran during 2016-2017. The IC50 values were calculated in both the...

Spectrophotometric Methods for Simultaneous Determination of Oxytetracycline HCl and Flunixin Meglumine in Their Veterinary Pharmaceutical Formulation.

Journal of analytical methods in chemistry

Merey HA, Abd-Elmonem MS, Nazlawy HN, Zaazaa HE.
PMID: 28811956
J Anal Methods Chem. 2017;2017:2321572. doi: 10.1155/2017/2321572. Epub 2017 Jul 24.

Four precise, accurate, selective, and sensitive UV-spectrophotometric methods were developed and validated for the simultaneous determination of a binary mixture of Oxytetracycline HCl (OXY) and Flunixin Meglumine (FLU). The first method, dual wavelength (DW), depends on measuring the difference...

Anti-Leishmanial and Immunomodulatory Effects of Epigallocatechin 3-O-Gallate on .

Iranian journal of parasitology

Saduqi M, Sharifi I, Babaei Z, Keyhani A, Mostafavi M, Hakimi Parizi M, Ghasemian M, Bamorovat M, Sharifi F, Aflatoonian MR, Sharififar F, Ghasemi Nejad P, Khosravi A, Salarkia E, Varma RS.
PMID: 32099555
Iran J Parasitol. 2019 Oct-Dec;14(4):521-533.

BACKGROUND: Pentavalent antimonials such as meglumine antimoniate (MA, Glucantime), are the first-line treatment against leishmaniasis, but at present, they have basically lost their efficacy. This study was aimed to explore epigallocatechin 3-O-gallate (EGCG), alone or in combination with MA...

Showing 1 to 12 of 224 entries