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Showing 1 to 12 of 209 entries
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A Combination of Candesartan Cilexetil/hydrochlorothiazide (HCTZ), 8/12.5 mg, has a Similar Antihypertensive Efficacy and is Better Tolerated than Lisinopril/HCTZ, 10/12.5 mg.

Blood pressure

T McINNES G, Istad H, Keinänen-Kiukaanniemi S, VAN Mierlo HFCM.
PMID: 28425809
Blood Press. 2000;9:61. doi: 10.1080/080370500439344.

Monotherapy with an antihypertensive agent is likely to achieve a desirable lowering of blood pressure in about 50% of patients. The remaining proportion of patients are likely to be only partially responsive or unresponsive, even if appropriate dose adjustments...

Ameliorative effects of β-sitosterol on some biochemical indices of hypertension in wistar albino rats.

African journal of medicine and medical sciences

Olaiya CO, Esan AM, Alabi TD.
PMID: 26690542
Afr J Med Med Sci. 2014 Sep;43:157-166.

BACKGROUND: Cardiovascular diseases presently rank high as leading causes of death globally. The increasing acceptability of phytomedicine is due to the increasing inefficacy of many modern drugs used for the control of many diseases. The aim of this study...

A Single-Center, Open-Label, Randomized, Parallel-Group Study Assessing the Differences Between an Angiotensin II Receptor Antagonist and an Angiotensin-Converting Enzyme Inhibitor in Hypertensive Patients with Congestive Heart Failure: The Research for Efficacy of Angiotensin II Receptor Antagonist in Hypertensive Patients with Congestive Heart Failure Study.

Current therapeutic research, clinical and experimental

Totsuka N, Awata N, Takahashi K, Yamamura H, Nakamura J, Tsuchikane E, Kobayashi Y, Nishibe A, Terai K.
PMID: 24944358
Curr Ther Res Clin Exp. 2003 Feb;64(2):81-94. doi: 10.1016/S0011-393X(03)00020-1.

BACKGROUND: Angiotensin II receptor blockers (ARBs) and angiotensin-converting enzyme inhibitors (ACEIs) have been used to treat congestive heart failure (CHF). According to a MEDLINE search, however, few studies are available on the clinical differences between ARBs and ACEIs in...

A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals.

Pathogens & immunity

Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, Hatano H.
PMID: 28936485
Pathog Immun. 2017;2(3):310-334. doi: 10.20411/pai.v2i3.207. Epub 2017 Aug 02.

BACKGROUND: In HIV infection, lymphoid tissue is disrupted by fibrosis. Angiotensin converting enzyme inhibitors have anti-fibrotic properties. We completed a pilot study to assess whether the addition of lisinopril to antiretroviral therapy (ART) reverses fibrosis of gut tissue, and...

Diffuse leukoencephalopathy and subacute parkinsonism as an early manifestation of systemic lupus erythematosus.

Case reports in neurological medicine

Tse GG, Santos-Ocampo AS, Chow DC, McMurtray AM, Nakamoto BK.
PMID: 24369514
Case Rep Neurol Med. 2013;2013:367185. doi: 10.1155/2013/367185. Epub 2013 Nov 28.

Parkinsonism in SLE is rare. Diffuse leukoencephalopathy is equally uncommon and is associated with a poor prognosis. We present a single case of a 50-year-old Filipino man who presented with a generalized discoid rash after starting lisinopril. The rash...

Adherence to EBM guidelines in clinical practice.

The International journal of risk & safety in medicine

Khafizianova RKh, Burykin IM.
PMID: 26639710
Int J Risk Saf Med. 2015;27:S53-4. doi: 10.3233/JRS-150687.

BACKGROUND: Adequate and rational pharmacotherapy is an important element of rehabilitation of patients with myocardial infarction. Orders of the Ministry of Health of the Russian Federation, domestic and international guidelines, and scientific publications - all contain a complete algorithm...

Expression of Ca(2+) Transport Genes in Platelets and Endothelial Cells in Hypertension.

Hypertension (Dallas, Tex. : 1979)

Mountian, Baba-Aïssa F, Jonas JC, Humbert De Smedt, Wuytack F, Parys JB.
PMID: 11208768
Hypertension. 2001 Jan;37(1):135-141. doi: 10.1161/01.hyp.37.1.135.

-Altered Ca(2+) handling is observed in different cells in essential hypertension. We investigated the expression of sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) and inositol 1,4,5-trisphosphate receptor (IP(3)R) isoforms in platelets and aortic endothelial cells (EC) isolated from spontaneously hypertensive (SHR) and...

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Bayes M, Rabasseda X, Prous JR.
PMID: 11980386
Methods Find Exp Clin Pharmacol. 2002 Jan-Feb;24(1):37-55.

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses, which has been retrieved from the Clinical Studies knowledge area of Prous Science Integrity, the world's first drug discovery and development...

Interpretation of the ALLHAT interim analysis and implications for the treatment of patients with BPH.

Prostate cancer and prostatic diseases

Kirby RS, Pool JL.
PMID: 12497091
Prostate Cancer Prostatic Dis. 2000 Nov;3(3):152-156. doi: 10.1038/sj.pcan.4500475.

The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) was designed to see if the effects of doxazosin, amlodipine and lisinopril were superior to those of chlorthalidone on the incidence of cardiovascular disease in high-risk patients with...

Frontiers in congestive heart failure: comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure.

Congestive heart failure (Greenwich, Conn.)

Tepper D.
PMID: 12029202
Congest Heart Fail. 2000 Jan-Feb;6(1):41.

No abstract available.

Effect of helicokinins and ACE inhibitors on water balance and development of Heliothis virescens larvae.

Journal of insect physiology

Seinsche A, Dyker H, Lösel P, Backhaus D, Scherkenbeck J.
PMID: 10891570
J Insect Physiol. 2000 Nov 01;46(11):1423-1431. doi: 10.1016/s0022-1910(00)00065-2.

The diuretic activity of the helicokinins I (YFSPWG-amide), II (VRFSPWG-amide) and III (KVKFSAWG-amide) was tested on Heliothis virescens larvae. All three kinins increased fluid secretion in isolated Malpighian tubules in a dose-dependent manner. Injections into the haemolymph caused a...

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Bayes M.
PMID: 17440629
Methods Find Exp Clin Pharmacol. 2007 Mar;29(2):153-73.

Agomelatine, AGRO-100, AIDSVAX gp120 B/E, alfimeprase, aliskiren fumarate, ALVAC vCP1452, alvocidib hydrochloride, ambrisentan, AME-527, AN-0128, apadenoson, ARRY-142886, asenapine maleate, axitinib, azimilide hydrochloride; Belimumab, bevacizumab, biolimus A9, BiovaxID, bryostatin 1; Cannabidiol, celgosivir, CG-1940/CG-8711, CKD-501, collagen-PVP, CpG-10101, CTL-102, CTL-102/CB-1954; D-4F, darusentan,...

Showing 1 to 12 of 209 entries