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Showing 1 to 12 of 18211 entries
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A high plasma concentration of TNF-alpha is associated with dementia in centenarians.

The journals of gerontology. Series A, Biological sciences and medical sciences

Bruunsgaard H, Andersen-Ranberg K, Jeune B, Pedersen AN, Skinhøj P, Pedersen BK.
PMID: 10462168
J Gerontol A Biol Sci Med Sci. 1999 Jul;54(7):M357-64. doi: 10.1093/gerona/54.7.m357.

BACKGROUND: Inflammatory mechanisms and immune activation have been hypothesized to play a role in the pathogenesis of age-associated diseases such as dementia and atherosclerosis. The purpose of this study was to evaluate the plasma concentration of tumor necrosis factor...

Nursing home admission for African Americans with Alzheimer's disease.

The journals of gerontology. Series A, Biological sciences and medical sciences

Miller SC, Prohaska TR, Furner SE.
PMID: 10462169
J Gerontol A Biol Sci Med Sci. 1999 Jul;54(7):M365-9. doi: 10.1093/gerona/54.7.m365.

BACKGROUND: For African Americans with Alzheimer's disease (AD), little is known about the time to, and risk factors for, nursing home admission (NHA). Using Consortium To Establish a Registry for Alzheimer's Disease (CERAD) data, this study provides information on...

Female sensitivity to diet and irradiation treatments underlies sex-mortality differentials in the Mediterranean fruit fly.

The journals of gerontology. Series A, Biological sciences and medical sciences

Carey JR, Liedo P, Müller HG, Wang JL, Love B, Harshman L, Partridge L.
PMID: 11213272
J Gerontol A Biol Sci Med Sci. 2001 Feb;56(2):B89-93. doi: 10.1093/gerona/56.2.b89.

Large-scale experiments on medflies that were subjected to sterilizing doses of ionizing radiation (plus intact controls) and maintained on either sugar-only or full, protein-enriched diets revealed that, whereas the mortality trajectories of both intact and irradiated male cohorts maintained...

Sildenafil citrate (VIAGRA) improves erectile function in elderly patients with erectile dysfunction: a subgroup analysis.

The journals of gerontology. Series A, Biological sciences and medical sciences

Wagner G, Montorsi F, Auerbach S, Collins M.
PMID: 11213274
J Gerontol A Biol Sci Med Sci. 2001 Feb;56(2):M113-9. doi: 10.1093/gerona/56.2.m113.

BACKGROUND: The prevalence of erectile dysfunction (ED) increases with advancing age, with a particularly high prevalence of ED in elderly patients with diabetes. In the United States it is estimated that approximately 45% of men aged 65 to 69...

Use of an ambulation assistive device predicts functional decline associated with hospitalization.

The journals of gerontology. Series A, Biological sciences and medical sciences

Mahoney JE, Sager MA, Jalaluddin M.
PMID: 10051860
J Gerontol A Biol Sci Med Sci. 1999 Feb;54(2):M83-8. doi: 10.1093/gerona/54.2.m83.

BACKGROUND: Loss of functional independence occurs frequently with hospitalization. In community-dwelling elders, lower extremity disability is an important predictor of functional loss. Ambulation assistive devices (canes, walkers), as markers of lower extremity disability, may predict functional decline associated with...

Effects of lifelong moderate caloric restriction on levels of neuropeptide Y, proopiomelanocortin, and galanin mRNA.

The journals of gerontology. Series A, Biological sciences and medical sciences

McShane TM, Wilson ME, Wise PM.
PMID: 10026650
J Gerontol A Biol Sci Med Sci. 1999 Jan;54(1):B14-21. doi: 10.1093/gerona/54.1.b14.

We are interested in how neuropeptides that regulate both food intake and reproductive function change with age and how life-prolonging moderate caloric restriction may influence the expression of these neuropeptides. We measured neuropeptide Y (NPY) and proopiomelanocortin (POMC) mRNA...

Commentary: nuclear receptors and myosin heavy chain gene expression in the aged myocardium.

The journals of gerontology. Series A, Biological sciences and medical sciences

Boheler KR.
PMID: 10026652
J Gerontol A Biol Sci Med Sci. 1999 Jan;54(1):B28-9. doi: 10.1093/gerona/54.1.b28.

No abstract available.

Application of exogenously regulatable promoter systems to transgenic models for the study of aging.

The journals of gerontology. Series A, Biological sciences and medical sciences

Morgan WW, Richardson A, Sharp ZD, Walter CA.
PMID: 10026653
J Gerontol A Biol Sci Med Sci. 1999 Jan;54(1):B30-40; discussion B41-2. doi: 10.1093/gerona/54.1.b30.

Transgenic mouse and gene knockout technologies offer powerful tools for dissecting the roles of specific genes in the process of aging. Tke interpretation of the results of such studies is limited, however, by the fact that the gene of...

Effects of age and gender on cardiovascular responses to phenylephrine.

The journals of gerontology. Series A, Biological sciences and medical sciences

Turner MJ, Mier CM, Spina RJ, Ehsani AA.
PMID: 10026658
J Gerontol A Biol Sci Med Sci. 1999 Jan;54(1):M17-24. doi: 10.1093/gerona/54.1.m17.

BACKGROUND: The age-associated impairment in left ventricular (LV) systolic function appears to be mostly detectable during exercise or sympathetic stimulation. We hypothesized that the decline in cardiac function could be unmasked by an acute increase in afterload induced by...

Longevity and the epsilon2 allele of apolipoprotein E: the Finnish Centenarians Study.

The journals of gerontology. Series A, Biological sciences and medical sciences

Frisoni GB, Louhija J, Geroldi C, Trabucchi M.
PMID: 11213279
J Gerontol A Biol Sci Med Sci. 2001 Feb;56(2):M75-8. doi: 10.1093/gerona/56.2.m75.

BACKGROUND: Whether and which genetic factors affect human longevity is unclear. This study assesses the association between the epsilon2 allele of apolipoprotein E (APOE), a putative longevity gene, and extremely old age.METHODS: This study is based on all centenarians...

Asset and Health Dynamics Among the Oldest Old (AHEAD): initial results from the longitudinal study. Introduction.

The journals of gerontology. Series B, Psychological sciences and social sciences

Myers GC, Juster FT, Suzman RM.
PMID: 9215353
J Gerontol B Psychol Sci Soc Sci. 1997 May;52:v-viii.

No abstract available.

Transfer behavior within the family: results from the Asset and Health Dynamics Study.

The journals of gerontology. Series B, Psychological sciences and social sciences

McGarry K, Schoeni RF.
PMID: 9215360
J Gerontol B Psychol Sci Soc Sci. 1997 May;52:82-92.

When individuals fall on hard times, can they rely on their family for financial support? In view of proposed reductions in public assistance programs, it is important to understand the mechanisms through which families provide support for their members....

Showing 1 to 12 of 18211 entries