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Showing 1 to 12 of 1007 entries
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Influence of isoflurane on the diastolic pressure-flow relationship and critical occlusion pressure during arterial CABG surgery: a randomized controlled trial.

PeerJ

Hinz J, Mansur A, Hanekop GG, Weyland A, Popov AF, Schmitto JD, Grüne FF, Bauer M, Kazmaier S.
PMID: 26966644
PeerJ. 2016 Jan 26;4:e1619. doi: 10.7717/peerj.1619. eCollection 2016.

The effects of isoflurane on the determinants of blood flow during Coronary Artery Bypass Graft (CABG) surgery are not completely understood. This study characterized the influence of isoflurane on the diastolic Pressure-Flow (P-F) relationship and Critical Occlusion Pressure (COP)...

Comparison of hemodynamic response to adrenaline infiltration in children undergoing cleft palate repair during general anesthesia with sevoflurane and isoflurane.

Journal of anaesthesiology, clinical pharmacology

Gunnam PR, Durga P, Gurajala I, Kaluvala PR, Veerabathula P, Ramachandran G.
PMID: 27006534
J Anaesthesiol Clin Pharmacol. 2016 Jan-Mar;32(1):12-7. doi: 10.4103/0970-9185.175650.

BACKGROUND AND AIMS: Systemic absorption of adrenaline often used for infiltration during cleft palate surgery leads to adverse hemodynamic responses. These hemodynamic responses may be attenuated by the volatile anesthetics. This study aims to compare the hemodynamic responses to...

Solubility of volatile anesthetics in plasma substitutes, albumin, intravenous fat emulsions, perfluorochemical emulsion, and aqueous solutions.

Journal of anesthesia

Shim JC, Kaminoh Y, Tashiro C, Miyamoto Y, Yoo HK.
PMID: 28921091
J Anesth. 1996 Dec;10(4):276-281. doi: 10.1007/BF02483395.

Using the gas chromatographic headspace sampling technique, we determined the solubility of volatile anesthetics (halothane, enflurane, isoflurane, and sevoflurane) in plasma substitutes, albumin solution, intravenous fat emulsions, perfluorochemical FC-43 emulsion, and aqueous solutions at 37°C. The order of magnitude...

Effects and interaction of nicardipine and volatile anesthetics in the rat heart-lung preparation.

Journal of anesthesia

Kashimoto S, Nakamura T, Kume M, Nonaka A, Kumazawa T.
PMID: 28921205
J Anesth. 1994 Mar;8(1):78-83. doi: 10.1007/BF02482760.

The effects of the calcium channel blocker nicardipine (N) and the volatile anesthetics halothane (H), enflurane (E), isoflurane (I), and sevoflurane (S) on myocardial metabolism after postischemic reperfusion were assessed in the isolated rat heart-lung preparation. Wistar-ST rats were...

Continuous positive airway pressure oxygenation during one-lung ventilation with 50% nitrous oxide and isoflurane in oxygen.

Journal of anesthesia

Taneyama C, Fujita T, Kohno N, Otagiri T, Goto H.
PMID: 28921233
J Anesth. 1995 Sep;9(3):285-288. doi: 10.1007/BF02479880.

No abstract available.

Emulsified isoflurane combined with therapeutic hypothermia improves survival and neurological outcomes in a rat model of cardiac arrest.

Experimental and therapeutic medicine

Wu MJ, Zhang YJ, Yu H, Liu B.
PMID: 28450915
Exp Ther Med. 2017 Mar;13(3):891-898. doi: 10.3892/etm.2017.4044. Epub 2017 Jan 13.

Emulsified isoflurane (EIso), when introduced following cardiopulmonary resuscitation (CPR), significantly improves survival and neurological outcomes in a rat model of cardiac arrest (CA). The present study aimed to examine whether EIso combined with therapeutic hypothermia (TH) confers an additive...

Potential of (99m)Tc-MIBI SPECT imaging for evaluating non-alcoholic steatohepatitis induced by methionine-choline-deficient diet in mice.

EJNMMI research

Rokugawa T, Uehara T, Higaki Y, Matsushima S, Obata A, Arano Y, Abe K.
PMID: 26116119
EJNMMI Res. 2014 Dec;4(1):57. doi: 10.1186/s13550-014-0057-z. Epub 2014 Oct 09.

BACKGROUND: Hepatic mitochondrial dysfunction has been implicated in pathological conditions leading to non-alcoholic steatohepatitis (NASH). Technetium-99 m-2-methoxyisobutyl-isonitrile ((99m)Tc-MIBI), a lipophilic cationic myocardial perfusion agent, is retained in the mitochondria depending on membrane potential. The aim of this study was...

Emulsified isoflurane anesthesia decreases brain-derived neurotrophic factor expression and induces cognitive dysfunction in adult rats.

Experimental and therapeutic medicine

Zhang F, Zhu ZQ, Liu DX, Zhang C, Gong QH, Zhu YH.
PMID: 25009603
Exp Ther Med. 2014 Aug;8(2):471-477. doi: 10.3892/etm.2014.1769. Epub 2014 Jun 10.

Post-operative cognitive dysfunction (POCD) is a severe complication characterized by cognitive decline in patients following anesthesia and surgery. Previous studies have suggested that volatile anesthetics, for example isoflurane, may contribute to such impairment. In the present study, the effects...

Touch-free measurement of body temperature using close-up thermography of the ocular surface.

MethodsX

Vogel B, Wagner H, Gmoser J, Wörner A, Löschberger A, Peters L, Frey A, Hofmann U, Frantz S.
PMID: 27284532
MethodsX. 2016 May 09;3:407-16. doi: 10.1016/j.mex.2016.05.002. eCollection 2016.

In experimental animal research body temperature (BT) is measured for the objective determination of an animals' physiological condition. Invasive, probe-based measurements are stressful and can influence experimental outcome. Alternatively BT can be determined touch-free from the emitted heat of...

A novel, clinically relevant use of a piglet model to study the effects of anesthetics on the developing brain.

Clinical and translational medicine

Whitaker EE, Bissonnette B, Miller AD, Koppert TL, Tobias JD, Pierson CR, Christofi FL.
PMID: 26757938
Clin Transl Med. 2016 Mar;5(1):2. doi: 10.1186/s40169-015-0079-9. Epub 2016 Jan 12.

BACKGROUND: Anesthesia-induced neurotoxicity research in the developing brain must rely upon an unimpeachable animal model and a standardized treatment approach. In this manner, identification of mechanisms of action may be undertaken. The goal of this study was to develop...

Management of super-refractory status epilepticus with isoflurane and hypothermia.

Frontiers in neurology

Zhumadilov A, Gilman CP, Viderman D.
PMID: 25674075
Front Neurol. 2015 Jan 28;5:286. doi: 10.3389/fneur.2014.00286. eCollection 2014.

Super-refractory status epilepticus (SRSE) is defined as status epilepticus that continues 24 h or more after the onset of anesthesia, and includes those cases in which epilepsy is recurrent upon treatment reduction. We describe the presentation and successful management...

HIF-1α Mediates Isoflurane-Induced Vascular Protection in Subarachnoid Hemorrhage.

Annals of clinical and translational neurology

Milner E, Johnson AW, Nelson JW, Harries MD, Gidday JM, Han BH, Zipfel GJ.
PMID: 25909079
Ann Clin Transl Neurol. 2015 Apr;2(4):325-37. doi: 10.1002/acn3.170. Epub 2015 Feb 21.

OBJECTIVE: Outcome after aneurysmal subarachnoid hemorrhage (SAH) depends critically on delayed cerebral ischemia (DCI) - a process driven primarily by vascular events including cerebral vasospasm, microvessel thrombosis, and microvascular dysfunction. This study sought to determine the impact of postconditioning...

Showing 1 to 12 of 1007 entries