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Showing 1 to 12 of 108 entries
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Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells.

Oncotarget

Abrams SL, Ruvolo PP, Ruvolo VR, Ligresti G, Martelli AM, Cocco L, Ratti S, Tafuri A, Steelman LS, Candido S, Libra M, McCubrey JA.
PMID: 29100331
Oncotarget. 2017 Aug 24;8(44):76525-76557. doi: 10.18632/oncotarget.20408. eCollection 2017 Sep 29.

A critical problem in leukemia as well as other cancer therapies is the development of chemotherapeutic drug-resistance. We have developed models of hematopoietic drug resistance that are based on expression of dominant-negative TP53 [TP53 (DN)] or constitutively-active MEK1 [MEK1(CA)]...

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Abrams SL, Ruvolo PP, Ruvolo VR, et al. Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells. Oncotarget. 2017;8(44):76525-76557doi: 10.18632/oncotarget.20408.
Abrams, S. L., Ruvolo, P. P., Ruvolo, V. R., Ligresti, G., Martelli, A. M., Cocco, L., Ratti, S., Tafuri, A., Steelman, L. S., Candido, S., Libra, M., & McCubrey, J. A. (2017). Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells. Oncotarget, 8(44), 76525-76557. https://doi.org/10.18632/oncotarget.20408
Abrams, Stephen L, et al. "Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells." Oncotarget vol. 8,44 (2017): 76525-76557. doi: https://doi.org/10.18632/oncotarget.20408
Abrams SL, Ruvolo PP, Ruvolo VR, Ligresti G, Martelli AM, Cocco L, Ratti S, Tafuri A, Steelman LS, Candido S, Libra M, McCubrey JA. Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells. Oncotarget. 2017 Aug 24;8(44):76525-76557. doi: 10.18632/oncotarget.20408. eCollection 2017 Sep 29. PMID: 29100331; PMCID: PMC5652725.
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Interleukin-3: Promises and Perspectives.

Hematology (Amsterdam, Netherlands)

Mangi MH, Newland AC.
PMID: 27416283
Hematology. 1998;3(1):55-66. doi: 10.1080/10245332.1998.11752123.

Interleukin-3 (IL-3) is a multipotent hematopoietic growth factor produced by activated T-cells, monocytes/macrophages and stroma cells. Human IL-3 gene is located on chromosome 5 near segment 5q31. The high affinity receptor for human IL-3 is composed of alpha and...

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Mangi MH, Newland AC. Interleukin-3: Promises and Perspectives. Hematology. 1998;3(1):55-66doi: 10.1080/10245332.1998.11752123.
Mangi, M. H., & Newland, A. C. (1998). Interleukin-3: Promises and Perspectives. Hematology (Amsterdam, Netherlands), 3(1), 55-66. https://doi.org/10.1080/10245332.1998.11752123
Mangi, M H, and Newland, A C. "Interleukin-3: Promises and Perspectives." Hematology (Amsterdam, Netherlands) vol. 3,1 (1998): 55-66. doi: https://doi.org/10.1080/10245332.1998.11752123
Mangi MH, Newland AC. Interleukin-3: Promises and Perspectives. Hematology. 1998;3(1):55-66. doi: 10.1080/10245332.1998.11752123. PMID: 27416283.
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Colony Stimulating Activities of GM-CSF, G-CSF and IL-3 on Blast Progenitors from Acute Myeloblastic Leukemia.

Leukemia & lymphoma

Motoji T, Takanashi M, Masuda M, Nakayama K, Oshimi K, Mizoguchi H.
PMID: 27457045
Leuk Lymphoma. 1990;2(6):407-14. doi: 10.3109/10428199009069294.

The colony stimulating activities (CSAs) of recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF), recombinant granulocyte colony-stimulating factor (rG-CSF) and recombinant interleukin-3 (rIL-3) on blast cells from various types of acute myeloblastic leukemia (AML) patients were studied using an in vitro blast...

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Motoji T, Takanashi M, Masuda M, et al. Colony Stimulating Activities of GM-CSF, G-CSF and IL-3 on Blast Progenitors from Acute Myeloblastic Leukemia. Leuk Lymphoma. 1990;2(6):407-14doi: 10.3109/10428199009069294.
Motoji, T., Takanashi, M., Masuda, M., Nakayama, K., Oshimi, K., & Mizoguchi, H. (1990). Colony Stimulating Activities of GM-CSF, G-CSF and IL-3 on Blast Progenitors from Acute Myeloblastic Leukemia. Leukemia & lymphoma, 2(6), 407-14. https://doi.org/10.3109/10428199009069294
Motoji, T, et al. "Colony Stimulating Activities of GM-CSF, G-CSF and IL-3 on Blast Progenitors from Acute Myeloblastic Leukemia." Leukemia & lymphoma vol. 2,6 (1990): 407-14. doi: https://doi.org/10.3109/10428199009069294
Motoji T, Takanashi M, Masuda M, Nakayama K, Oshimi K, Mizoguchi H. Colony Stimulating Activities of GM-CSF, G-CSF and IL-3 on Blast Progenitors from Acute Myeloblastic Leukemia. Leuk Lymphoma. 1990;2(6):407-14. doi: 10.3109/10428199009069294. PMID: 27457045.
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Effect of STAT3 inhibitor in chronic myeloid leukemia associated signaling pathway: a mathematical modeling, simulation and systems biology study.

3 Biotech

Kumar H, Tichkule S, Raj U, Gupta S, Srivastava S, Varadwaj PK.
PMID: 28330111
3 Biotech. 2016 Jun;6(1):40. doi: 10.1007/s13205-015-0357-7. Epub 2016 Jan 27.

Chronic myeloid leukemia (CML) is a hematopoietic stem-cell disorder which proliferates due to abnormal growth of basophil cells. Several proangiogenic molecules have been reported to be associated in CML progression, including the hepatocyte growth factor (HGF). However, detail mechanism...

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Kumar H, Tichkule S, Raj U, et al. Effect of STAT3 inhibitor in chronic myeloid leukemia associated signaling pathway: a mathematical modeling, simulation and systems biology study. 3 Biotech. 2016;6(1):40doi: 10.1007/s13205-015-0357-7.
Kumar, H., Tichkule, S., Raj, U., Gupta, S., Srivastava, S., & Varadwaj, P. K. (2016). Effect of STAT3 inhibitor in chronic myeloid leukemia associated signaling pathway: a mathematical modeling, simulation and systems biology study. 3 Biotech, 6(1), 40. https://doi.org/10.1007/s13205-015-0357-7
Kumar, Himansu, et al. "Effect of STAT3 inhibitor in chronic myeloid leukemia associated signaling pathway: a mathematical modeling, simulation and systems biology study." 3 Biotech vol. 6,1 (2016): 40. doi: https://doi.org/10.1007/s13205-015-0357-7
Kumar H, Tichkule S, Raj U, Gupta S, Srivastava S, Varadwaj PK. Effect of STAT3 inhibitor in chronic myeloid leukemia associated signaling pathway: a mathematical modeling, simulation and systems biology study. 3 Biotech. 2016 Jun;6(1):40. doi: 10.1007/s13205-015-0357-7. Epub 2016 Jan 27. PMID: 28330111; PMCID: PMC4729759.
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Liquid secondary ion mass spectrometry analysis of permethylated, n-hexylamine derivatized oligosaccharides. Application to baculovirus expressed mouse interleukin-3.

Journal of the American Society for Mass Spectrometry

Hogeland KE, Arbogast B, Deinzer ML.
PMID: 24243045
J Am Soc Mass Spectrom. 1992 May;3(4):345-52. doi: 10.1016/1044-0305(92)87062-4.

Reductive amination with n-hexylamine followed by permethylation was used as a procedure for the liquid secondary ion mass spectrometry (LSIMS) analysis of Asn-linked oligosaccharides. Initial experiments with this procedure were performed on maltoheptaose. These experiments show that exhaustive methylation...

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Hogeland KE, Arbogast B, Deinzer ML. Liquid secondary ion mass spectrometry analysis of permethylated, n-hexylamine derivatized oligosaccharides. Application to baculovirus expressed mouse interleukin-3. J Am Soc Mass Spectrom. 1992;3(4):345-52doi: 10.1016/1044-0305(92)87062-4.
Hogeland, K. E., Arbogast, B., & Deinzer, M. L. (1992). Liquid secondary ion mass spectrometry analysis of permethylated, n-hexylamine derivatized oligosaccharides. Application to baculovirus expressed mouse interleukin-3. Journal of the American Society for Mass Spectrometry, 3(4), 345-52. https://doi.org/10.1016/1044-0305(92)87062-4
Hogeland, K E, et al. "Liquid secondary ion mass spectrometry analysis of permethylated, n-hexylamine derivatized oligosaccharides. Application to baculovirus expressed mouse interleukin-3." Journal of the American Society for Mass Spectrometry vol. 3,4 (1992): 345-52. doi: https://doi.org/10.1016/1044-0305(92)87062-4
Hogeland KE, Arbogast B, Deinzer ML. Liquid secondary ion mass spectrometry analysis of permethylated, n-hexylamine derivatized oligosaccharides. Application to baculovirus expressed mouse interleukin-3. J Am Soc Mass Spectrom. 1992 May;3(4):345-52. doi: 10.1016/1044-0305(92)87062-4. PMID: 24243045.
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Effect of IL-3 on Globin Gene Expression in a Human Erythroleukemia Cell Line.

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica

Cheng XD, Xie HY, Qian RL.
PMID: 12114990
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 1999;31(4):385-389.

A human erythroleukemia cell line(K562 cells)was used as a model to study the effect of interleukin-3(IL-3) on human globin gene expression in the cells. The results showed that the beta-globin gene was not expressed in uninduced K562 cells however,...

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Cheng XD, Xie HY, Qian RL. Effect of IL-3 on Globin Gene Expression in a Human Erythroleukemia Cell Line. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 1999;31(4):385-389
Cheng, X. D., Xie, H. Y., & Qian, R. L. (1999). Effect of IL-3 on Globin Gene Expression in a Human Erythroleukemia Cell Line. Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica, 31(4), 385-389.
Cheng, Xiao-Dong, et al. "Effect of IL-3 on Globin Gene Expression in a Human Erythroleukemia Cell Line." Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica vol. 31,4 (1999): 385-389.
Cheng XD, Xie HY, Qian RL. Effect of IL-3 on Globin Gene Expression in a Human Erythroleukemia Cell Line. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 1999;31(4):385-389. PMID: 12114990.
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Anti- schistosomular activity of human monocytes/macrophages in response to interleukin-3 and granulocyte-macrophage colonystimulating factor stimulation.

Mediators of inflammation

Gold D, Nissimov L, Lengy J, Keisari Y.
PMID: 18475576
Mediators Inflamm. 1994;3(5):329-33. doi: 10.1155/S0962935194000451.

Human monocytes, co-incubated for 7 days in culture with GM-CSF or IL-3 but not with IFN-gamma, exerted a variable schistosotnulicidal effect on Schistosoma mansoni parasites when grown in 96-well round-bottomed plates but not in flat-bottomed plates. Addition of LPS...

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Gold D, Nissimov L, Lengy J, et al. Anti- schistosomular activity of human monocytes/macrophages in response to interleukin-3 and granulocyte-macrophage colonystimulating factor stimulation. Mediators Inflamm. 1994;3(5):329-33doi: 10.1155/S0962935194000451.
Gold, D., Nissimov, L., Lengy, J., & Keisari, Y. (1994). Anti- schistosomular activity of human monocytes/macrophages in response to interleukin-3 and granulocyte-macrophage colonystimulating factor stimulation. Mediators of inflammation, 3(5), 329-33. https://doi.org/10.1155/S0962935194000451
Gold, D, et al. "Anti- schistosomular activity of human monocytes/macrophages in response to interleukin-3 and granulocyte-macrophage colonystimulating factor stimulation." Mediators of inflammation vol. 3,5 (1994): 329-33. doi: https://doi.org/10.1155/S0962935194000451
Gold D, Nissimov L, Lengy J, Keisari Y. Anti- schistosomular activity of human monocytes/macrophages in response to interleukin-3 and granulocyte-macrophage colonystimulating factor stimulation. Mediators Inflamm. 1994;3(5):329-33. doi: 10.1155/S0962935194000451. PMID: 18475576; PMCID: PMC2365577.
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Human eosinophil isolation and the measurement of apoptosis.

Methods in molecular medicine

Kankaanranta H, de Souza PM, Giembycz MA, Lindsay MA.
PMID: 21312124
Methods Mol Med. 2000;44:99-110. doi: 10.1385/1-59259-072-1:99.

Eosinophils have been implicated in allergic diseases, such as bronchial asthma, which is characterized by elevated eosinophil numbers in the bronchoalveolar lavage fluid and peripheral blood. Their accumulation and activation within the airway mucosa is thought to cause tissue...

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Kankaanranta H, de Souza PM, Giembycz MA, et al. Human eosinophil isolation and the measurement of apoptosis. Methods Mol Med. 2000;44:99-110doi: 10.1385/1-59259-072-1:99.
Kankaanranta, H., de Souza, P. M., Giembycz, M. A., & Lindsay, M. A. (2000). Human eosinophil isolation and the measurement of apoptosis. Methods in molecular medicine, 4499-110. https://doi.org/10.1385/1-59259-072-1:99
Kankaanranta, H, et al. "Human eosinophil isolation and the measurement of apoptosis." Methods in molecular medicine vol. 44 (2000): 99-110. doi: https://doi.org/10.1385/1-59259-072-1:99
Kankaanranta H, de Souza PM, Giembycz MA, Lindsay MA. Human eosinophil isolation and the measurement of apoptosis. Methods Mol Med. 2000;44:99-110. doi: 10.1385/1-59259-072-1:99. PMID: 21312124.
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Haemopoietic growth factors: their role in cell development and their clinical use.

Cytotechnology

Testa NG, Dexter TM.
PMID: 22358868
Cytotechnology. 1989 Dec;2(4):259-67. doi: 10.1007/BF00364992.

Mature blood cells are derived from haemopoietic stem cells which grow and proliferate to give rise to progenitor cells more restricted in their proliferation and differentiation capacity. These in turn give rise to cells belonging to any of the...

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Testa NG, Dexter TM. Haemopoietic growth factors: their role in cell development and their clinical use. Cytotechnology. 1989;2(4):259-67doi: 10.1007/BF00364992.
Testa, N. G., & Dexter, T. M. (1989). Haemopoietic growth factors: their role in cell development and their clinical use. Cytotechnology, 2(4), 259-67. https://doi.org/10.1007/BF00364992
Testa, N G, and Dexter, T M. "Haemopoietic growth factors: their role in cell development and their clinical use." Cytotechnology vol. 2,4 (1989): 259-67. doi: https://doi.org/10.1007/BF00364992
Testa NG, Dexter TM. Haemopoietic growth factors: their role in cell development and their clinical use. Cytotechnology. 1989 Dec;2(4):259-67. doi: 10.1007/BF00364992. PMID: 22358868.
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Regulation of interleukin 3 expression in normal and autocrine transformed hematopoietic cells (Review).

International journal of oncology

Wang X, McCubrey J.
PMID: 21533475
Int J Oncol. 1997 May;10(5):989-1001. doi: 10.3892/ijo.10.5.989.

Over the past decade, the regulation of cytokine expression has been intensively studied. Control of cytokine expression has important clinical implications. Cytokine therapy has been utilized in the treatment of many diseases including: cancer, bone marrow transplantation, inflammation, rheumatoid...

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Wang X, McCubrey J. Regulation of interleukin 3 expression in normal and autocrine transformed hematopoietic cells (Review). Int J Oncol. 1997;10(5):989-1001doi: 10.3892/ijo.10.5.989.
Wang, X., & McCubrey, J. (1997). Regulation of interleukin 3 expression in normal and autocrine transformed hematopoietic cells (Review). International journal of oncology, 10(5), 989-1001. https://doi.org/10.3892/ijo.10.5.989
Wang, X, and McCubrey, J. "Regulation of interleukin 3 expression in normal and autocrine transformed hematopoietic cells (Review)." International journal of oncology vol. 10,5 (1997): 989-1001. doi: https://doi.org/10.3892/ijo.10.5.989
Wang X, McCubrey J. Regulation of interleukin 3 expression in normal and autocrine transformed hematopoietic cells (Review). Int J Oncol. 1997 May;10(5):989-1001. doi: 10.3892/ijo.10.5.989. PMID: 21533475.
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Improved Survival and Hematopoietic Differentiation of Murine Embryonic Stem Cells on Electrospun Polycaprolactone Nanofiber.

Cell journal

Dehdilani N, Shamsasenjan K, Movassaghpour A, Akbarzadehlaleh P, Amoughli Tabrizi B, Parsa H, Sabagi F.
PMID: 26862522
Cell J. 2016;17(4):629-38. doi: 10.22074/cellj.2016.3835. Epub 2016 Jan 17.

OBJECTIVE: Three-dimensional (3D) biomimetic nanofiber scaffolds have widespread ap- plications in biomedical tissue engineering. They provide a suitable environment for cel- lular adhesion, survival, proliferation and differentiation, guide new tissue formation and development, and are one of the outstanding...

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Dehdilani N, Shamsasenjan K, Movassaghpour A, et al. Improved Survival and Hematopoietic Differentiation of Murine Embryonic Stem Cells on Electrospun Polycaprolactone Nanofiber. Cell J. 2016;17(4):629-38doi: 10.22074/cellj.2016.3835.
Dehdilani, N., Shamsasenjan, K., Movassaghpour, A., Akbarzadehlaleh, P., Amoughli Tabrizi, B., Parsa, H., & Sabagi, F. (2016). Improved Survival and Hematopoietic Differentiation of Murine Embryonic Stem Cells on Electrospun Polycaprolactone Nanofiber. Cell journal, 17(4), 629-38. https://doi.org/10.22074/cellj.2016.3835
Dehdilani, Nima, et al. "Improved Survival and Hematopoietic Differentiation of Murine Embryonic Stem Cells on Electrospun Polycaprolactone Nanofiber." Cell journal vol. 17,4 (2016): 629-38. doi: https://doi.org/10.22074/cellj.2016.3835
Dehdilani N, Shamsasenjan K, Movassaghpour A, Akbarzadehlaleh P, Amoughli Tabrizi B, Parsa H, Sabagi F. Improved Survival and Hematopoietic Differentiation of Murine Embryonic Stem Cells on Electrospun Polycaprolactone Nanofiber. Cell J. 2016;17(4):629-38. doi: 10.22074/cellj.2016.3835. Epub 2016 Jan 17. PMID: 26862522; PMCID: PMC4746413.
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Value Added Impact of Both Point-of-Care and Laboratory Lactic Acid Analysis When Emergently Evaluating Cancer Patients.

Oncology and therapy

Bouobda GT, Gonzalez CE, Phipps RA, Middleton LP.
PMID: 32700044
Oncol Ther. 2020 Dec;8(2):277-284. doi: 10.1007/s40487-020-00118-0. Epub 2020 Jun 02.

INTRODUCTION: Cancer patients are immunosuppressed and may present to an emergency department with atypical symptoms. In the emergency setting, it is important ascertain rapidly if lactic acid levels are high, either due to sepsis or tumor lysis syndrome, to...

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Bouobda GT, Gonzalez CE, Phipps RA, et al. Value Added Impact of Both Point-of-Care and Laboratory Lactic Acid Analysis When Emergently Evaluating Cancer Patients. Oncol Ther. 2020;8(2):277-284doi: 10.1007/s40487-020-00118-0.
Bouobda, G. T., Gonzalez, C. E., Phipps, R. A., & Middleton, L. P. (2020). Value Added Impact of Both Point-of-Care and Laboratory Lactic Acid Analysis When Emergently Evaluating Cancer Patients. Oncology and therapy, 8(2), 277-284. https://doi.org/10.1007/s40487-020-00118-0
Bouobda, Georges T, et al. "Value Added Impact of Both Point-of-Care and Laboratory Lactic Acid Analysis When Emergently Evaluating Cancer Patients." Oncology and therapy vol. 8,2 (2020): 277-284. doi: https://doi.org/10.1007/s40487-020-00118-0
Bouobda GT, Gonzalez CE, Phipps RA, Middleton LP. Value Added Impact of Both Point-of-Care and Laboratory Lactic Acid Analysis When Emergently Evaluating Cancer Patients. Oncol Ther. 2020 Dec;8(2):277-284. doi: 10.1007/s40487-020-00118-0. Epub 2020 Jun 02. PMID: 32700044; PMCID: PMC7683647.
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Showing 1 to 12 of 108 entries