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Showing 1 to 12 of 508 entries
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Depletion of tumor-associated macrophages slows the growth of chemically induced mouse lung adenocarcinomas.

Frontiers in immunology

Fritz JM, Tennis MA, Orlicky DJ, Lin H, Ju C, Redente EF, Choo KS, Staab TA, Bouchard RJ, Merrick DT, Malkinson AM, Dwyer-Nield LD.
PMID: 25505466
Front Immunol. 2014 Nov 25;5:587. doi: 10.3389/fimmu.2014.00587. eCollection 2014.

Chronic inflammation is a risk factor for lung cancer, and low-dose aspirin intake reduces lung cancer risk. However, the roles that specific inflammatory cells and their products play in lung carcinogenesis have yet to be fully elucidated. In mice,...

Metabolic and hormonal effects of antenatal betamethasone after 35 weeks of gestation.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

Sifianou P, Thanou V, Karga H.
PMID: 25964731
J Pediatr Pharmacol Ther. 2015 Mar-Apr;20(2):138-43. doi: 10.5863/1551-6776-20.2.138.

BACKGROUND: Antenatal corticosteroid therapy recently has been considered for term and near-term infants, in addition to preterm infants, delivered by elective cesarean section, with the aim of preventing an adverse respiratory outcome.OBJECTIVES: The objective of this study was to...

Insulin and IGF-I receptors and tyrosine kinase activity in carp ovaries: changes with reproductive cycle.

Fish physiology and biochemistry

Gutiérrez J, Párrizas M, Carneiro N, Maestro JL, Maestro MA, Planas J.
PMID: 24202482
Fish Physiol Biochem. 1993 Jul;11(1):247-54. doi: 10.1007/BF00004572.

Insulin and insulin-like growth factor I (IGF-I) receptors from carp ovaries were semipurified with wheat germ agglutinin at different moments of the reproductive cycle and their binding characteristics and tyrosine kinase activity were studied. Specific receptors for insulin and...

IGF-1 Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers.

Journal of diabetes research

Aydin F, Kaya A, Karapinar L, Kumbaraci M, Imerci A, Karapinar H, Karakuzu C, Incesu M.
PMID: 23671876
J Diabetes Res. 2013;2013:567834. doi: 10.1155/2013/567834. Epub 2013 Feb 26.

Objectives. To investigate insulin-like growth factor I (IGF-1) levels in response to hyperbaric oxygen therapy (HBOT) for diabetic foot ulcers and to determine whether IGF-1 is a predictive indicator of wound healing in patients with diabetic foot ulcers. Design...

Different thresholds of tissue-specific dose-responses to growth hormone in short prepubertal children.

BMC endocrine disorders

Decker R, Nygren A, Kriström B, Nierop AF, Gustafsson J, Albertsson-Wikland K, Dahlgren J.
PMID: 23116291
BMC Endocr Disord. 2012 Nov 01;12:26. doi: 10.1186/1472-6823-12-26.

BACKGROUND: In addition to stimulating linear growth in children, growth hormone (GH) influences metabolism and body composition. These effects should be considered when individualizing GH treatment as dose-dependent changes in metabolic markers have been reported.HYPOTHESIS: There are different dose-dependent...

Differential Expression of Insulin-Like Growth Factor-I Receptor on Human Bone Marrow-Derived Mesenchymal Stem Cells Induced by Tumor Necrosis Factor-α.

International journal of organ transplantation medicine

Sahraean Z, Ayatollahi M, Yaghobi R, Ziaei R.
PMID: 25013674
Int J Organ Transplant Med. 2014;5(1):15-22.

BACKGROUND: Cell-based therapy has been implicated in the treatment of liver diseases. Mesenchymal stem cells from various sources such as bone marrow are available. These cells are one of the major candidates in cell therapy. The production of insulin-like...

Effect of exercise performed at anaerobic threshold on serum growth hormone and body fat distribution in obese patients with type 2 diabetes.

Obesity research & clinical practice

Yamaguchi T, Saiki A, Endo K, Miyashita Y, Shirai K.
PMID: 24331006
Obes Res Clin Pract. 2011 Jan-Mar;5(1):e1-e78. doi: 10.1016/j.orcp.2010.11.001.

SUMMARY: The mechanism by which exercise reduces visceral fat is not fully understood. We have reported that increase in serum growth hormone (GH) level by mild exercise is associated with increase in lipolysis in type 2 diabetes (T2D), and...

Acromegaly with Normal Insulin-Like Growth Factor-1 Levels and Congestive Heart Failure as the First Clinical Manifestation.

Endocrinology and metabolism (Seoul, Korea)

Lee HM, Lee SH, Yang IH, Hwang IK, Hwang YC, Ahn KJ, Chung HY, Hwang HJ, Jeong IK.
PMID: 25491785
Endocrinol Metab (Seoul). 2015 Sep;30(3):395-401. doi: 10.3803/EnM.2015.30.3.395. Epub 2015 Sep 22.

The leading cause of morbidity and mortality in patients with acromegaly is cardiovascular complications. Myocardial exposure to excessive growth hormone can cause ventricular hypertrophy, hypertension, arrhythmia, and diastolic dysfunction. However, congestive heart failure as a result of systolic dysfunction...

Acarbose, lente carbohydrate, and prebiotics promote metabolic health and longevity by stimulating intestinal production of GLP-1.

Open heart

McCarty MF, DiNicolantonio JJ.
PMID: 25685364
Open Heart. 2015 Jan 29;2(1):e000205. doi: 10.1136/openhrt-2014-000205. eCollection 2015.

The α-glucosidase inhibitor acarbose, which slows carbohydrate digestion and blunts postprandial rises in plasma glucose, has long been used to treat patients with type 2 diabetes or glucose intolerance. Like metformin, acarbose tends to aid weight control, postpone onset...

Relationship between serum insulin-like growth factor-1, IGF binding protein-3 levels and body height before and after gonadotropin-releasing hormone agonist therapy.

Annals of pediatric endocrinology & metabolism

Song HS, Choi WB, Song JS, Hwang IT, Yang S.
PMID: 25654067
Ann Pediatr Endocrinol Metab. 2014 Dec;19(4):208-13. doi: 10.6065/apem.2014.19.4.208. Epub 2014 Dec 31.

PURPOSE: The gonadotropin-releasing hormone agonist (GnRHa) is widely used to treat patients with precocious puberty. However, its effect on growth is often difficult to predict because of the diverse nature of its causes and presentation. This study aims to...

Insulin-like growth factor-I and fast growth-hormone levels in mild and moderately malnourished children.

Asia Pacific journal of clinical nutrition

Wan Nazaimoona WM, Osman A, Ng ML, Tan TT, Wu LL, Sakinah O, Khalid AK.
PMID: 24323236
Asia Pac J Clin Nutr. 1992 Dec;1(4):207-10.

Insulin-like growth factor-I (IGF-I)and fasting growth hormone levels were measured in a group of 255 children (163 males and 92 females. age ranged 6-17 years) of varying pubertal development and body mass index (BMI); well-nourished (BMI> 18). mildly-malnourished (BMI...

The melanocortin receptor type 3 agonist d-Trp(8)-γMSH decreases inflammation and muscle wasting in arthritic rats.

Journal of cachexia, sarcopenia and muscle

Gómez-SanMiguel AB, Martín AI, Nieto-Bona MP, Fernández-Galaz C, Villanúa MÁ, López-Calderón A.
PMID: 27066320
J Cachexia Sarcopenia Muscle. 2016 Mar;7(1):79-89. doi: 10.1002/jcsm.12036. Epub 2015 May 11.

BACKGROUND: Chronic inflammatory diseases induce cachexia that increases mortality and morbidity of the illness. Adjuvant-induced arthritis is an experimental model of rheumatoid arthritis that is associated with body weight loss and muscle wasting. Alpha-melanocyte stimulating hormone has an anti-inflammatory...

Showing 1 to 12 of 508 entries