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Showing 1 to 12 of 936 entries
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[Immunosuppressive agents].

Recenti progressi in medicina

Mowbray JF.
PMID: 5537180
Recenti Prog Med. 1970 Apr;48(4):360-72.

No abstract available.

Importance of Accurate Diagnosis in Pyoderma Gangrenosum.

Archives of craniofacial surgery

Kim YS, Kim HK, Han YS.
PMID: 28913208
Arch Craniofac Surg. 2014 Dec;15(3):138-141. doi: 10.7181/acfs.2014.15.3.138. Epub 2014 Dec 23.

Pyoderma gangrenosum is a rare inflammatory reactive dermatosis marked by painful cutaneous ulcers. Diagnosis of pyoderma gangrenosum is usually made based on past medical history and after the exclusion of other possible diseases based on the clinical manifestations of...

Proximal Tubular Injury in Medullary Rays Is an Early Sign of Acute Tacrolimus Nephrotoxicity.

Journal of transplantation

Cosner D, Zeng X, Zhang PL.
PMID: 26199736
J Transplant. 2015;2015:142521. doi: 10.1155/2015/142521. Epub 2015 Jun 24.

Tacrolimus (FK506) is one of the principal immunosuppressive agents used after solid organ transplantations to prevent allograft rejection. Chronic renal injury induced by tacrolimus is characterized by linear fibrosis in the medullary rays; however, the early morphologic findings of...

Genes and podocytes - new insights into mechanisms of podocytopathy.

Frontiers in endocrinology

Bierzynska A, Soderquest K, Koziell A.
PMID: 25667580
Front Endocrinol (Lausanne). 2015 Jan 23;5:226. doi: 10.3389/fendo.2014.00226. eCollection 2014.

After decades of primarily morphological study, positional cloning of the NPHS1 gene was the landmark event that established aberrant podocyte genetics as a pivotal cause of malfunction of the glomerular filter. This ended any uncertainty whether genetic mutation plays...

Belimumab in systemic lupus erythematosus (SLE): evidence-to-date and clinical usefulness.

Therapeutic advances in musculoskeletal disease

Guerreiro Castro S, Isenberg DA.
PMID: 28344669
Ther Adv Musculoskelet Dis. 2017 Mar;9(3):75-85. doi: 10.1177/1759720X17690474. Epub 2017 Mar 01.

Systemic lupus erythematosus (SLE) is a complex autoimmune rheumatic disease with multiple presentations, whose management presents many challenges. Many disease modifying or immunosuppressive drugs have been used with limited success, especially in patients with more severe disease activity. Belimumab...

Cutaneous Squamous Cell Carcinomas in Organ Transplant Recipients.

Journal of clinical medicine

Chockalingam R, Downing C, Tyring SK.
PMID: 26239556
J Clin Med. 2015 Jun 03;4(6):1229-39. doi: 10.3390/jcm4061229.

Non-melanoma skin cancers represent a major cause of morbidity after organ transplantation. Squamous cell carcinomas (SCC) are the most common cutaneous malignancies seen in this population, with a 65-100 fold greater incidence in organ transplant recipients compared to the...

Clinical Study of Porokeratosis Associated with Immunosuppressive Therapy in Renal Transplant Recipients.

Annals of dermatology

Han YW, Kim YJ, Kim HO, Park YM.
PMID: 27303185
Ann Dermatol. 2008 Dec;20(4):167-71. doi: 10.5021/ad.2008.20.4.167. Epub 2008 Dec 31.

BACKGROUND: The etiology of porokeratosis (PK) remains unknown, but immunosuppression is known to be a factor in the pathogenesis of PK and it may also exacerbate PK.OBJECTIVE: The aim of this study was to examine the clinical characteristics of...

An atypical presentation of adult-onset Still's disease complicated by pulmonary hypertension and macrophage activation syndrome treated with immunosuppression: a case-based review of the literature.

Pulmonary circulation

Mehta MV, Manson DK, Horn EM, Haythe J.
PMID: 27162622
Pulm Circ. 2016 Mar;6(1):136-42. doi: 10.1086/685112.

Pulmonary arterial hypertension (PAH) is a known complication of rheumatologic diseases, but it is only rarely associated with adult-onset Still's disease (AOSD). We describe the case of a 30-year-old woman who presented in a pulmonary hypertension crisis and was...

Nonimmunologic targets of immunosuppressive agents in podocytes.

Kidney research and clinical practice

Yoo TH, Fornoni A.
PMID: 26484025
Kidney Res Clin Pract. 2015 Jun;34(2):69-75. doi: 10.1016/j.krcp.2015.03.003. Epub 2015 Apr 09.

Proteinuria is a characteristic finding in glomerular diseases and is closely associated with renal outcomes. In addition, therapeutic interventions that reduce proteinuria improve renal prognosis. Accumulating evidence has demonstrated that podocytes act as key modulators of glomerular injury and...

Entero-vesical fistulas in CROHN'S disease: A case series report and review of the literature.

International journal of surgery case reports

Vagianos C, Malgarinos G, Spyropoulos C, Triantafillidis JK.
PMID: 29546021
Int J Surg Case Rep. 2017 Nov 24;41:477-480. doi: 10.1016/j.ijscr.2017.11.035. eCollection 2017.

BACKGROUND: Entero-vesical fistula (EVF) is an abnormal link between the enteric lumen and the urinary bladder. Crohn's disease (CD) represents, nowadays, the most common cause in the formation of this fistula.MATERIALS AND METHODS: The aim of this study was...

Role of serum interleukin-6 in deciding therapy for multidrug resistant oral lichen planus.

Journal of clinical and experimental dentistry

Goel S, Marwah A, Kaushik S, Garg VK, Gupta S.
PMID: 26535093
J Clin Exp Dent. 2015 Oct 01;7(4):e477-82. doi: 10.4317/jced.52376. eCollection 2015 Oct.

BACKGROUND: Oral lichen planus (OLP) is a T cell mediated immune response. T cells locally present in the involved tissues release cytokines like interleukin-6 (IL-6), which contributes to pathogenesis of OLP. Also IL-6 has been associated with multidrug resistance...

Granulomatosis with polyangiitis presenting as a choroidal tumor.

Case reports in rheumatology

Masuda T, Izumi Y, Takeshita H, Kawahara C, Tsuji Y, Kurohama H, Iwanaga N, Inamoto M, Kase K, Ito M, Kawakami A, Migita K.
PMID: 25949841
Case Rep Rheumatol. 2015;2015:271823. doi: 10.1155/2015/271823. Epub 2015 Apr 08.

Granulomatosis with polyangiitis (GPA) sometimes involves the eye orbit; however, choroidal involvements in GPA had been rarely reported. We report a rare case presenting with a choroidal mass in an 83-year-old Japanese woman who presented with left eye pain....

Showing 1 to 12 of 936 entries