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Standardisation of the factor H autoantibody assay.


Watson R, Lindner S, Bordereau P, Hunze EM, Tak F, Ngo S, Zipfel PF, Skerka C, Dragon-Durey MA, Marchbank KJ.
PMID: 23891327
Immunobiology. 2014 Jan;219(1):9-16. doi: 10.1016/j.imbio.2013.06.004. Epub 2013 Jun 26.

The screening of all atypical haemolytic uraemic syndrome (aHUS) patients for factor H autoantibodies is best practice. However, there is no consensus assay for the reporting of factor H autoantibody titres. In this study, three European complement laboratories with...

Otologic Manifestation in IgG4-Related Systemic Disease.

Clinical and experimental otorhinolaryngology

Cho HK, Lee YJ, Chung JH, Koo JW.
PMID: 21461065
Clin Exp Otorhinolaryngol. 2011 Mar;4(1):52-4. doi: 10.3342/ceo.2011.4.1.52. Epub 2011 Feb 07.

IgG4-related systemic disease, including autoimmune pancreatitis, is a multi-organ disorder characterized by elevated serum immunoglobulin G4 (IgG4) concentration and IgG4-positive plasma cell infiltration. We report a case of a 66-year-old woman with IgG4-related hearing disorder, presenting with fluctuating mixed...

DDX6 post-transcriptionally down-regulates miR-143/145 expression through host gene NCR143/145 in cancer cells.

Biochimica et biophysica acta

Iio A, Takagi T, Miki K, Naoe T, Nakayama A, Akao Y.
PMID: 23932921
Biochim Biophys Acta. 2013 Oct;1829(10):1102-10. doi: 10.1016/j.bbagrm.2013.07.010. Epub 2013 Aug 09.

In various human malignancies, widespread dysregulation of microRNA (miRNA) expression is reported to occur and affects various cell growth programs. Recent studies suggest that the expression levels of miRNAs that act as tumor suppressors are frequently reduced in cancers...

Association between Helicobacter pylori and Barrett's esophagus, erosive esophagitis, and gastroesophageal reflux symptoms.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Rubenstein JH, Inadomi JM, Scheiman J, Schoenfeld P, Appelman H, Zhang M, Metko V, Kao JY.
PMID: 23988686
Clin Gastroenterol Hepatol. 2014 Feb;12(2):239-45. doi: 10.1016/j.cgh.2013.08.029. Epub 2013 Aug 27.

BACKGROUND & AIMS: Infection with Helicobacter pylori, particularly the cytotoxin-associated gene A (cagA)+ strain, is believed to protect against Barrett's esophagus, but it is not clear if it protects against gastroesophageal reflux disease (GERD). We aimed to determine whether...

ALG1-CDG: a new case with early fatal outcome.


Rohlfing AK, Rust S, Reunert J, Tirre M, Du Chesne I, Wemhoff S, Meinhardt F, Hartmann H, Das AM, Marquardt T.
PMID: 24157261
Gene. 2014 Jan 25;534(2):345-51. doi: 10.1016/j.gene.2013.10.013. Epub 2013 Oct 21.

Congenital disorders of glycosylation (CDG) are a growing group of inherited metabolic disorders where enzymatic defects in the formation or processing of glycolipids and/or glycoproteins lead to variety of different diseases. The deficiency of GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, encoded by the...

Tropisetron as a neuroprotective agent against glutamate-induced excitotoxicity and mechanisms of action.


Swartz MM, Linn DM, Linn CL.
PMID: 23727438
Neuropharmacology. 2013 Oct;73:111-21. doi: 10.1016/j.neuropharm.2013.05.020. Epub 2013 May 29.

The objective of this study was to determine the neuroprotective role of tropisetron on retinal ganglion cells (RGCs) as well as to explore the possible mechanisms associated with alpha7 nAChR-induced neuroprotection. Adult pig RGCs were isolated from all other...

Poor positive predictive value of serum immunoglobulin G4 concentrations in the diagnosis of immunoglobulin G4-related sclerosing disease.

Asia Pacific allergy

Yun J, Wienholt L, Adelstein S.
PMID: 25097853
Asia Pac Allergy. 2014 Jul;4(3):172-6. doi: 10.5415/apallergy.2014.4.3.172. Epub 2014 Jul 29.

BACKGROUND: Immunoglobulin G4 (IgG4)-related sclerosing disease is a recently described clinicopathological entity with diverse manifestations including, amongst others, autoimmune pancreatitis, sclerosing cholangitis, sclerosing sialadenitis and retroperitoneal fibrosis. Elevated serum IgG4 concentration has been described as the hallmark of this...

Amelioration of palmitate-induced insulin resistance in C₂C₁₂ muscle cells by rooibos (Aspalathus linearis).

Phytomedicine : international journal of phytotherapy and phytopharmacology

Mazibuko SE, Muller CJ, Joubert E, de Beer D, Johnson R, Opoku AR, Louw J.
PMID: 23639187
Phytomedicine. 2013 Jul 15;20(10):813-9. doi: 10.1016/j.phymed.2013.03.018. Epub 2013 Apr 29.

Increased levels of free fatty acids (FFAs), specifically saturated free fatty acids such as palmitate are associated with insulin resistance of muscle, fat and liver. Skeletal muscle, responsible for up to 80% of the glucose disposal from the peripheral...

Binding of plasma proteins to titanium dioxide nanotubes with different diameters.

International journal of nanomedicine

Kulkarni M, Flašker A, Lokar M, Mrak-Poljšak K, Mazare A, Artenjak A, Čučnik S, Kralj S, Velikonja A, Schmuki P, Kralj-Iglič V, Sodin-Semrl S, Iglič A.
PMID: 25733829
Int J Nanomedicine. 2015 Feb 18;10:1359-73. doi: 10.2147/IJN.S77492. eCollection 2015.

Titanium and titanium alloys are considered to be one of the most applicable materials in medical devices because of their suitable properties, most importantly high corrosion resistance and the specific combination of strength with biocompatibility. In order to improve...

A Markov Analysis of Screening for Late-Onset Cytomegalovirus Disease in Cytomegalovirus High-Risk Kidney Transplant Recipients.

Clinical journal of the American Society of Nephrology : CJASN

Puttarajappa CM, Hariharan S, Smith KJ.
PMID: 29025787
Clin J Am Soc Nephrol. 2018 Feb 07;13(2):290-298. doi: 10.2215/CJN.05080517. Epub 2017 Oct 12.

BACKGROUND AND OBJECTIVES: Management strategies are unclear for late-onset cytomegalovirus infection occurring beyond 6 months of antiviral prophylaxis in cytomegalovirus high-risk (cytomegalovirus IgG positive to cytomegalovirus IgG negative) kidney transplant recipients. Hybrid strategies (prophylaxis followed by screening) have been...

N-acetylcysteine and the human serum components that inhibit bacterial invasion of gingival epithelial cells prevent experimental periodontitis in mice.

Journal of periodontal & implant science

Alam J, Baek KJ, Choi YS, Kim YC, Choi Y.
PMID: 25568806
J Periodontal Implant Sci. 2014 Dec;44(6):266-73. doi: 10.5051/jpis.2014.44.6.266. Epub 2014 Dec 31.

PURPOSE: We previously reported that human serum significantly reduces the invasion of various oral bacterial species into gingival epithelial cells in vitro. The aims of the present study were to characterize the serum component(s) responsible for the inhibition of...

Activation of TAK1 by Sef-S induces apoptosis in 293T cells.

Cellular signalling

Sun X, Wang Y, Yang S, Ren F, Xia Y, Chang Z.
PMID: 23770285
Cell Signal. 2013 Oct;25(10):2039-46. doi: 10.1016/j.cellsig.2013.06.006. Epub 2013 Jun 11.

Sef (similar expression to fgf genes, also named IL-17RD) was identified as a negative regulator of fibroblast growth factor signaling. Sef-S, an alternative splice isoform of Sef, inhibits FGF-induced NIH3T3 cell proliferation. Here we report that Sef-S physically interacts...

Showing 1 to 12 of 143708 entries