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Showing 1 to 12 of 374 entries
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Comparison between efficacy of imipramine and transcutaneous electrical nerve stimulation in the prophylaxis of chronic tension-type headache: a randomized controlled clinical trial.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Mousavi SA, Mirbod SM, Khorvash F.
PMID: 22279461
J Res Med Sci. 2011 Jul;16(7):923-7.

BACKGROUND: Chronic tension-type headache (CTTH) is recognized as the most common type of headache and can be further defined as either episodic or chronic. Regarding the chronic nature of CTTH and intolerance or side effects of drugs that are...

Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus.

Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences

Vahdati Hassani F, Naseri V, Razavi BM, Mehri S, Abnous K, Hosseinzadeh H.
PMID: 24401376
Daru. 2014 Jan 08;22(1):16. doi: 10.1186/2008-2231-22-16.

BACKGROUND: Antidepressants have been shown to affect levels of brain-derived neurotrophic factor (BDNF) and VGF (non-acronymic) whose transcriptions are dependent on cAMP response element binding protein (CREB) in long term treatment. The aim of this study was to verify...

Comparative efficacy of antidepressants on anxiety features in depression: A meta-analysis of double-blind studies of imipramine and moclobemide against placebo.

International journal of psychiatry in clinical practice

Delini-Stula A Cameron J Angst A.
PMID: 24921445
Int J Psychiatry Clin Pract. 2000;4(2):111-7. doi: 10.1080/13651500050518262.

INTRODUCTION: We carried out a meta-analysis of data for 950 depressed patients from all double-blind, placebo-controlled comparative studies of moclobemide against imipramine. The aim of the analysis was to determine: 1 if the two antidepressants reduce anxiety symptoms as...

Toluene induces depression-like behaviors in adult mice.

Toxicological research

Yang M, Kim SH, Kim JC, Shin T, Moon C.
PMID: 24278539
Toxicol Res. 2010 Dec;26(4):315-20. doi: 10.5487/TR.2010.26.4.315.

It has been clinically reported that toluene causes mental depression in humans. However, the detrimental effects of toluene exposure on brain function and the relation between features of mental depression and toluene exposure are poorly understood. This study evaluated...

A simple and sensitive HPLC method for analysis of imipramine in human plasma with UV detection and liquid-liquid extraction: Application in bioequivalence studies.

Research in pharmaceutical sciences

Rezazadeh M, Emami J.
PMID: 27168757
Res Pharm Sci. 2016 Mar-Apr;11(2):168-76.

High-performance liquid chromatography (HPLC) methods employing ultraviolet (UV) detector are not sufficiently sensitive to measure the low plasma concentrations following single oral dose of imipramine. Therefore, in the present study a simple, rapid and yet sensitive HPLC method with...

Antinociceptive and Anti-Inflammatory Activities of Teucrium persicum Boiss. Extract in Mice.

Scientifica

Miri A, Sharifi-Rad J, Tabrizian K, Nasiri AA.
PMID: 26649227
Scientifica (Cairo). 2015;2015:972827. doi: 10.1155/2015/972827. Epub 2015 Nov 16.

Background. Therapeutic properties of Teucrium species as antioxidant, antibacterial, analgesic, anticancer, diuretic, and tonic compounds have been proved earlier. Materials and Methods. In this study, the antinociceptive and anti-inflammatory effects of the aqueous extract of Teucrium persicum on chronic...

Neuroprotective effects of Nigella sativa extracts during germination on central nervous system.

Pharmacognosy magazine

Islam MH, Ahmad IZ, Salman MT.
PMID: 26109765
Pharmacogn Mag. 2015 May;11:S182-9. doi: 10.4103/0973-1296.157729.

BACKGROUND: Nigella sativa Linn. which has many acclaimed medicinal properties is an indigenous herbaceous plant and belongs to the Ranunculaceae family, which grows in countries bordering the Mediterranean Sea, Pakistan and India.OBJECTIVE: This study was designed to investigate the...

Repurposing psychiatric medicines to target activated microglia in anxious mild cognitive impairment and early Parkinson's disease.

American journal of neurodegenerative disease

Lauterbach EC.
PMID: 27073741
Am J Neurodegener Dis. 2016 Mar 01;5(1):29-51. eCollection 2016.

Anxiety is common in the Mild Cognitive Impairment (MCI) stage of Alzheimer's disease (AD) and the pre-motor stages of Parkinson's disease (PD). A concomitant and possible cause of this anxiety is microglial activation, also considered a key promoter of...

Memantine: New prospective in bipolar disorder treatment.

World journal of psychiatry

Serra G, Demontis F, Serra F, De Chiara L, Spoto A, Girardi P, Vidotto G, Serra G.
PMID: 25540723
World J Psychiatry. 2014 Dec 22;4(4):80-90. doi: 10.5498/wjp.v4.i4.80.

UNLABELLED: We review preclinical and clinical evidences strongly suggesting that memantine, an old drug currently approved for Alzheimer's dementia, is an effective treatment for acute mania and for the prevention of manic/hypomanic and depressive recurrences of manic-depressive illness. Lithium...

The International Journal of Neuropsychopharmacology.

The international journal of neuropsychopharmacology

Lerer B, Frazer A, Stahl S, Farde L, Lesch P.
PMID: 11343572
Int J Neuropsychopharmacol. 1998 Jul;1(1):1-2. doi: 10.1017/S1461145798009018.

Almost half a century ago, a series of remarkable therapeutic developments occurred and were soon recognised as milestones in the history of medicine. The introduction of lithium, chlorpromazine, imipramine and the monoamine oxidase inhibitors, within a few years of...

A Calorimetric Study of the Influence of Temperature on the Self-Association of Amphiphilic Antidepressant Drugs in Aqueous Solution.

Journal of colloid and interface science

Attwood D, Boitard E, Dubès J, Tachoire H.
PMID: 10873321
J Colloid Interface Sci. 2000 Jul 15;227(2):356-362. doi: 10.1006/jcis.2000.6908.

Relative apparent molar enthalpies have been determined as a function of concentration (0.0001 to 0.2 mol kg(-1)) by heat conduction calorimetry for aqueous solutions of the structurally related antidepressant drugs imipramine and clomipramine in water over the temperature range...

[Chronic pain treatment with antidepressants--metaanalysis].

Schmerz (Berlin, Germany)

Feuerstein TJ.
PMID: 12799822
Schmerz. 1997 Jun 13;11(3):213-26. doi: 10.1007/s004829700027.

Both preclinical and clinical evidence support the usefulness of antidepressants in chronic pain treatment. Monoamine uptake inhibitors influence the neurotransmissions of noradrenaline (NA) and/or serotonin (5-HT); their effect on nociception is thought to take place predominantly within the spinal...

Showing 1 to 12 of 374 entries