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Showing 1 to 12 of 449 entries
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A modified intraoral resin mouthguard to prevent self-mutilations in lesch-nyhan patients.

International journal of dentistry

Ragazzini G, Delucchi A, Calcagno E, Servetto R, Denotti G.
PMID: 25101126
Int J Dent. 2014;2014:396830. doi: 10.1155/2014/396830. Epub 2014 Jul 02.

Lesch-Nyhan syndrome, described in 1964 by Lesch and Nyhan, is a X-linked recessive disorder, occurring in 1 : 100000 to 1 : 380000 live births. LNS is characterized by a decrease in activity of hypoxanthine guanine phosphoribosyl transferase, an...

Quality Improvement of Pork Loin by Dry Aging.

Korean journal for food science of animal resources

Lee CW, Lee JR, Kim MK, Jo C, Lee KH, You I, Jung S.
PMID: 27433108
Korean J Food Sci Anim Resour. 2016;36(3):369-76. doi: 10.5851/kosfa.2016.36.3.369. Epub 2016 Jun 30.

This study aimed to investigate the effects of dry aging on the quality of pork loin. Longissimus lumborum muscles were dissected from the right half of five pork carcasses and were used as the control samples. The left halves...

Thermostable Xanthine Oxidase Activity from Bacillus pumilus RL-2d Isolated from Manikaran Thermal Spring: Production and Characterization.

Indian journal of microbiology

Sharma NK, Thakur S, Thakur N, Savitri, Bhalla TC.
PMID: 26843701
Indian J Microbiol. 2016 Mar;56(1):88-98. doi: 10.1007/s12088-015-0547-3. Epub 2015 Aug 21.

Xanthine oxidase is an important enzyme of purine metabolism that catalyzes the hydroxylation of hypoxanthine to xanthine and then xanthine to uric acid. A thermostable xanthine oxidase is being reported from a thermophilic organism RL-2d isolated from the Manikaran...

Self-injurious Behavior in a Young Child with Lesch-Nyhan Syndrome.

Indian journal of psychological medicine

Mohapatra S, Sahoo AJ.
PMID: 27833236
Indian J Psychol Med. 2016 Sep-Oct;38(5):477-479. doi: 10.4103/0253-7176.191389.

Lesch-Nyhan syndrome (LNS) is a rare inherited disorder caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyl transferase-1. Few reports on behavioral aspects especially self-injurious behavior in LNS patients are available. We report a case of LNS in an...

Release of(14)C-adenine derivatives from cerebral cortical slices: Effect of phenytoin and phenobarbital.

Neurochemical research

Lewin E, Bleck V.
PMID: 24271574
Neurochem Res. 1976 Aug;1(4):429-35. doi: 10.1007/BF00966234.

Both ouabain, 0.1 mM, and veratridine, 0.05 mM, increased the release of(14)C-labeled compounds from rat cortical slices prelabeled with(14)C-adenine and incubated in vitro. The increment in radioactivity released by both depolarizing agents was almost entirely a result of increases...

Hypoxanthine: a new paradigm to interpret the origin of transfusion toxicity.

Blood transfusion = Trasfusione del sangue

Casali E, Berni P, Spisni A, Baricchi R, Pertinhez TA.
PMID: 26674829
Blood Transfus. 2016 Nov;14(6):555-556. doi: 10.2450/2015.0177-15. Epub 2015 Dec 11.

No abstract available.

Guanylate requirement for patterning the postcephalic body region of the brine shrimp Artemia.

Roux's archives of developmental biology : the official organ of the EDBO

Hernandorena A.
PMID: 28305982
Rouxs Arch Dev Biol. 1993 Jan;203(1):74-82. doi: 10.1007/BF00539892.

Mycophenolic acid (MA) reduces growth and survival rates of Artemia larvae fed hypoxanthine. The inhibitory effect of MA is suppressed by dietary guanosine as expected for inosinate dehydrogenase inhibition. Pulse MA treatments lasting 24 h imposed on larvae from...

Separate de Novo and Salvage Purine Pools Are Involved in the Biosynthesis of Theobromine but Not Caffeine in Leaves of Coffea arabica L.

Plant physiology

Nazario GM, Lovatt CJ.
PMID: 12232013
Plant Physiol. 1993 Dec;103(4):1203-1210. doi: 10.1104/pp.103.4.1203.

In Coffea arabica leaves, the purine ring of theobromine (3,7-dimethylxanthine) and caffeine (1,3,7-trimethylxanthine) is provided by de novo purine biosynthesis: (a) [14C]glycine, [14C]bicarbonate, and [14C]formate were incorporated into inosine 5[prime]- monophosphate (IMP), sum of adenine nucleotides ([sigma]Ade), theobromine, and...

Nutrient absorption and utilization by wing and flight muscle morphs of the cricket Gryllus firmus: implications for the trade-off between flight capability and early reproduction.

Journal of insect physiology

Zera AJ, Brink T.
PMID: 10818248
J Insect Physiol. 2000 Aug 01;46(8):1207-1218. doi: 10.1016/s0022-1910(00)00041-x.

Absorption efficiency (AD, approximate digestibility, assimilation efficiency) of various macronutrients and conversion of absorbed nutrients to biomass (ECD) were compared among the two types of flightless morph and the flight-capable morph of the cricket, Gryllus firmus. No biologically significant...

Microanalyses of enzymes and metabolites in ischemia/reperfusion-induced partial-thickness skin wounds.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society

Im MJ, Angel MF, Vander Kolk CA, Manson PN.
PMID: 17166102
Wound Repair Regen. 1993 Oct;1(4):253-8. doi: 10.1046/j.1524-475X.1993.10411.x.

A transition zone between well-perfused proximal tissue and inadequately perfused distal tissue was evaluated histologically and biochemically in skin flaps. Cranially based pedicle flaps, 3 x 7.5 cm, were made on the backs of female Sprague-Dawley rats. Flap survival...

Hypoxanthine phosphoribosyltransferase activity in bovine embryos during the early embryonic development.

Theriogenology

Kita M, Imai H.
PMID: 16727321
Theriogenology. 1993 Aug;40(2):357-64. doi: 10.1016/0093-691x(93)90273-8.

The activity of hypoxanthine phosphoribosyltransferase (HPRT) was determined in the bovine embryo during early embryonic development. Microassay, using [(3)H] hypoxanthine, was improved to measure enzyme activity in the embryonic extract. This activity depended on the reaction time and the...

Preservation of oocyte and granulosa cell morphology in bovine preantral follicles cultured in vitro.

Theriogenology

Figueiredo JR, Hulshof SC, Van den Hurk R, Nusgens B, Bevers MM, Ectors FJ, Beckers JF.
PMID: 16727488
Theriogenology. 1994;41(6):1333-46. doi: 10.1016/0093-691x(94)90492-2.

Described in the present paper is a culture system that preserves oocyte and granulosa cell morphology in bovine preantral follicles during 5 d in vitro. The effects of additional hypoxanthine and energy substrata (i.e., pyruvate and glutamine) on the...

Showing 1 to 12 of 449 entries