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Tilia tomentosa pectins exhibit dual mode of action on phagocytes as β-glucuronic acid monomers are abundant in their rhamnogalacturonans I.

Carbohydrate polymers

Georgiev YN, Paulsen BS, Kiyohara H, Ciz M, Ognyanov MH, Vasicek O, Rise F, Denev PN, Lojek A, Batsalova TG, Dzhambazov BM, Yamada H, Lund R, Barsett H, Krastanov AI, Yanakieva IZ, Kratchanova MG.
PMID: 28917854
Carbohydr Polym. 2017 Nov 01;175:178-191. doi: 10.1016/j.carbpol.2017.07.073. Epub 2017 Jul 25.

Silver linden flowers contain different pectins (PSI-PSIII) with immunomodulating properties. PSI is a low-esterified pectic polysaccharide with predominant homogalacturonan region, followed by rhamnogalacturonan I (RGI) with arabinogalactan II and RGII (traces) domains. PSII and PSIII are unusual glucuronidated RGI...

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Georgiev YN, Paulsen BS, Kiyohara H, et al. Tilia tomentosa pectins exhibit dual mode of action on phagocytes as β-glucuronic acid monomers are abundant in their rhamnogalacturonans I. Carbohydr Polym. 2017;175:178-191doi: 10.1016/j.carbpol.2017.07.073.
Georgiev, Y. N., Paulsen, B. S., Kiyohara, H., Ciz, M., Ognyanov, M. H., Vasicek, O., Rise, F., Denev, P. N., Lojek, A., Batsalova, T. G., Dzhambazov, B. M., Yamada, H., Lund, R., Barsett, H., Krastanov, A. I., Yanakieva, I. Z., & Kratchanova, M. G. (2017). Tilia tomentosa pectins exhibit dual mode of action on phagocytes as β-glucuronic acid monomers are abundant in their rhamnogalacturonans I. Carbohydrate polymers, 175178-191. https://doi.org/10.1016/j.carbpol.2017.07.073
Georgiev, Yordan N, et al. "Tilia tomentosa pectins exhibit dual mode of action on phagocytes as β-glucuronic acid monomers are abundant in their rhamnogalacturonans I." Carbohydrate polymers vol. 175 (2017): 178-191. doi: https://doi.org/10.1016/j.carbpol.2017.07.073
Georgiev YN, Paulsen BS, Kiyohara H, Ciz M, Ognyanov MH, Vasicek O, Rise F, Denev PN, Lojek A, Batsalova TG, Dzhambazov BM, Yamada H, Lund R, Barsett H, Krastanov AI, Yanakieva IZ, Kratchanova MG. Tilia tomentosa pectins exhibit dual mode of action on phagocytes as β-glucuronic acid monomers are abundant in their rhamnogalacturonans I. Carbohydr Polym. 2017 Nov 01;175:178-191. doi: 10.1016/j.carbpol.2017.07.073. Epub 2017 Jul 25. PMID: 28917854.
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Suppression of PtrDUF579-3 Expression Causes Structural Changes of the Glucuronoxylan in Populus.

Frontiers in plant science

Song D, Gui J, Liu C, Sun J, Li L.
PMID: 27148318
Front Plant Sci. 2016 Apr 11;7:493. doi: 10.3389/fpls.2016.00493. eCollection 2016.

DUF579 (domain unknown function 579) genes have been reported to play diverse roles in cell wall biosynthesis, such as in glucuronoxylan (GX) synthesis. As GX is a major type of hemicelluloses in hard wood species, how DUF579 genes function...

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Song D, Gui J, Liu C, et al. Suppression of PtrDUF579-3 Expression Causes Structural Changes of the Glucuronoxylan in Populus. Front Plant Sci. 2016;7:493doi: 10.3389/fpls.2016.00493.
Song, D., Gui, J., Liu, C., Sun, J., & Li, L. (2016). Suppression of PtrDUF579-3 Expression Causes Structural Changes of the Glucuronoxylan in Populus. Frontiers in plant science, 7493. https://doi.org/10.3389/fpls.2016.00493
Song, Dongliang, et al. "Suppression of PtrDUF579-3 Expression Causes Structural Changes of the Glucuronoxylan in Populus." Frontiers in plant science vol. 7 (2016): 493. doi: https://doi.org/10.3389/fpls.2016.00493
Song D, Gui J, Liu C, Sun J, Li L. Suppression of PtrDUF579-3 Expression Causes Structural Changes of the Glucuronoxylan in Populus. Front Plant Sci. 2016 Apr 11;7:493. doi: 10.3389/fpls.2016.00493. eCollection 2016. PMID: 27148318; PMCID: PMC4827005.
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Composition of the cell wall of Chlorella fusca.

Planta

Loos E, Meindl D.
PMID: 24272476
Planta. 1982 Dec;156(3):270-3. doi: 10.1007/BF00393735.

Isolated cell walls of mature Chlorella fusca consisted of about 80% carbohydrate, 7% protein, and 13% unidentified material. Mannose and glucose were present in a ratio of about 2.7:1 and accounted for most of the carbohydrate. Minor components were...

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Loos E, Meindl D. Composition of the cell wall of Chlorella fusca. Planta. 1982;156(3):270-3doi: 10.1007/BF00393735.
Loos, E., & Meindl, D. (1982). Composition of the cell wall of Chlorella fusca. Planta, 156(3), 270-3. https://doi.org/10.1007/BF00393735
Loos, E, and Meindl, D. "Composition of the cell wall of Chlorella fusca." Planta vol. 156,3 (1982): 270-3. doi: https://doi.org/10.1007/BF00393735
Loos E, Meindl D. Composition of the cell wall of Chlorella fusca. Planta. 1982 Dec;156(3):270-3. doi: 10.1007/BF00393735. PMID: 24272476.
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The effects of glucuronic acid and N-acetyl-D-glucosamine on in vitro fertilisation of porcine oocytes.

Reproduction, fertility, and development

Schmidt K, Clark A, Mello A, Durfey C, Buck A, Boyd K, Whitaker BD.
PMID: 25585197
Reprod Fertil Dev. 2015 Jan 14; doi: 10.1071/RD14226. Epub 2015 Jan 14.

High incidences of polyspermic penetration continue to challenge researchers during porcine in vitro fertilisation (IVF). The aim of this study was to reduce the incidence of polyspermy by increasing the perivitelline space thickness with glucuronic acid and N-acetyl-D-glucosamine (GlcNAc)...

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Schmidt K, Clark A, Mello A, et al. The effects of glucuronic acid and N-acetyl-D-glucosamine on in vitro fertilisation of porcine oocytes. Reprod Fertil Dev. 2015;doi: 10.1071/RD14226.
Schmidt, K., Clark, A., Mello, A., Durfey, C., Buck, A., Boyd, K., & Whitaker, B. D. (2015). The effects of glucuronic acid and N-acetyl-D-glucosamine on in vitro fertilisation of porcine oocytes. Reproduction, fertility, and development, . https://doi.org/10.1071/RD14226
Schmidt, K, et al. "The effects of glucuronic acid and N-acetyl-D-glucosamine on in vitro fertilisation of porcine oocytes." Reproduction, fertility, and development vol. (2015). doi: https://doi.org/10.1071/RD14226
Schmidt K, Clark A, Mello A, Durfey C, Buck A, Boyd K, Whitaker BD. The effects of glucuronic acid and N-acetyl-D-glucosamine on in vitro fertilisation of porcine oocytes. Reprod Fertil Dev. 2015 Jan 14; doi: 10.1071/RD14226. Epub 2015 Jan 14. PMID: 25585197.
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Analysis of nucleotide diphosphate sugar dehydrogenases reveals family and group-specific relationships.

FEBS open bio

Freas N, Newton P, Perozich J.
PMID: 27047744
FEBS Open Bio. 2016 Jan 11;6(1):77-89. doi: 10.1002/2211-5463.12022. eCollection 2016 Jan.

UNLABELLED: UDP-glucose dehydrogenase (UDPGDH), UDP-N-acetyl-mannosamine dehydrogenase (UDPNAMDH) and GDP-mannose dehydrogenase (GDPMDH) belong to a family of NAD (+)-linked 4-electron-transfering oxidoreductases called nucleotide diphosphate sugar dehydrogenases (NDP-SDHs). UDPGDH is an enzyme responsible for converting UDP-d-glucose to UDP-d-glucuronic acid, a product...

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Freas N, Newton P, Perozich J. Analysis of nucleotide diphosphate sugar dehydrogenases reveals family and group-specific relationships. FEBS Open Bio. 2016;6(1):77-89doi: 10.1002/2211-5463.12022.
Freas, N., Newton, P., & Perozich, J. (2016). Analysis of nucleotide diphosphate sugar dehydrogenases reveals family and group-specific relationships. FEBS open bio, 6(1), 77-89. https://doi.org/10.1002/2211-5463.12022
Freas, Nicholas, et al. "Analysis of nucleotide diphosphate sugar dehydrogenases reveals family and group-specific relationships." FEBS open bio vol. 6,1 (2016): 77-89. doi: https://doi.org/10.1002/2211-5463.12022
Freas N, Newton P, Perozich J. Analysis of nucleotide diphosphate sugar dehydrogenases reveals family and group-specific relationships. FEBS Open Bio. 2016 Jan 11;6(1):77-89. doi: 10.1002/2211-5463.12022. eCollection 2016 Jan. PMID: 27047744; PMCID: PMC4794789.
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Exopolysaccharides enriched in rare sugars: bacterial sources, production, and applications.

Frontiers in microbiology

Roca C, Alves VD, Freitas F, Reis MA.
PMID: 25914689
Front Microbiol. 2015 Apr 10;6:288. doi: 10.3389/fmicb.2015.00288. eCollection 2015.

Microbial extracellular polysaccharides (EPS), produced by a wide range of bacteria, are high molecular weight biopolymers, presenting an extreme diversity in terms of chemical structure and composition. They may be used in many applications, depending on their chemical and...

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Roca C, Alves VD, Freitas F, et al. Exopolysaccharides enriched in rare sugars: bacterial sources, production, and applications. Front Microbiol. 2015;6:288doi: 10.3389/fmicb.2015.00288.
Roca, C., Alves, V. D., Freitas, F., & Reis, M. A. (2015). Exopolysaccharides enriched in rare sugars: bacterial sources, production, and applications. Frontiers in microbiology, 6288. https://doi.org/10.3389/fmicb.2015.00288
Roca, Christophe, et al. "Exopolysaccharides enriched in rare sugars: bacterial sources, production, and applications." Frontiers in microbiology vol. 6 (2015): 288. doi: https://doi.org/10.3389/fmicb.2015.00288
Roca C, Alves VD, Freitas F, Reis MA. Exopolysaccharides enriched in rare sugars: bacterial sources, production, and applications. Front Microbiol. 2015 Apr 10;6:288. doi: 10.3389/fmicb.2015.00288. eCollection 2015. PMID: 25914689; PMCID: PMC4392319.
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Interaction between dietary selenium and 2-acetylaminofluorene in the rat.

Biological trace element research

Cohen AM.
PMID: 24263569
Biol Trace Elem Res. 1983 Aug;5(4):307-15. doi: 10.1007/BF02987216.

The effect of dietary selenium on the metabolism of 2-acetylaminofluorene (AAF) and on its interaction with hepatic DNA was studied in male, Charles River rats. All studies were commenced at least 3 weeks after placing weanling rats on a...

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Cohen AM. Interaction between dietary selenium and 2-acetylaminofluorene in the rat. Biol Trace Elem Res. 1983;5(4):307-15doi: 10.1007/BF02987216.
Cohen, A. M. (1983). Interaction between dietary selenium and 2-acetylaminofluorene in the rat. Biological trace element research, 5(4), 307-15. https://doi.org/10.1007/BF02987216
Cohen, A M. "Interaction between dietary selenium and 2-acetylaminofluorene in the rat." Biological trace element research vol. 5,4 (1983): 307-15. doi: https://doi.org/10.1007/BF02987216
Cohen AM. Interaction between dietary selenium and 2-acetylaminofluorene in the rat. Biol Trace Elem Res. 1983 Aug;5(4):307-15. doi: 10.1007/BF02987216. PMID: 24263569.
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Mucilage chemical profile and antioxidant properties of giant swamp taro tubers.

Journal of food science and technology

Nguimbou RM, Boudjeko T, Njintang NY, Himeda M, Scher J, Mbofung CM.
PMID: 25477624
J Food Sci Technol. 2014 Dec;51(12):3559-67. doi: 10.1007/s13197-012-0906-6. Epub 2012 Dec 11.

The yellow (YP) and white (WP) sections of giant swamp taro (GST) contain 40.0 g/kg and 51.5 g/kg (dry wt) respectively of pure mucilage made up of D-glucose (44.95-78.85 %), D-galactose (8.70-25.35 %), D-mannose (3.20-10.45 %), D-arabinose (2.45-5.20 %)...

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Nguimbou RM, Boudjeko T, Njintang NY, et al. Mucilage chemical profile and antioxidant properties of giant swamp taro tubers. J Food Sci Technol. 2012;51(12):3559-67doi: 10.1007/s13197-012-0906-6.
Nguimbou, R. M., Boudjeko, T., Njintang, N. Y., Himeda, M., Scher, J., & Mbofung, C. M. (2014). Mucilage chemical profile and antioxidant properties of giant swamp taro tubers. Journal of food science and technology, 51(12), 3559-67. https://doi.org/10.1007/s13197-012-0906-6
Nguimbou, Richard Marcel, et al. "Mucilage chemical profile and antioxidant properties of giant swamp taro tubers." Journal of food science and technology vol. 51,12 (2014): 3559-67. doi: https://doi.org/10.1007/s13197-012-0906-6
Nguimbou RM, Boudjeko T, Njintang NY, Himeda M, Scher J, Mbofung CM. Mucilage chemical profile and antioxidant properties of giant swamp taro tubers. J Food Sci Technol. 2014 Dec;51(12):3559-67. doi: 10.1007/s13197-012-0906-6. Epub 2012 Dec 11. PMID: 25477624; PMCID: PMC4252446.
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Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis.

F1000Research

Armstrong AW, Wu J, Johnson MA, Grapov D, Azizi B, Dhillon J, Fiehn O.
PMID: 25580230
F1000Res. 2014 Oct 21;3:248. doi: 10.12688/f1000research.4709.1. eCollection 2014.

IMPORTANCE: While "omics" studies have advanced our understanding of inflammatory skin diseases, metabolomics is mostly an unexplored field in dermatology.OBJECTIVE: We sought to elucidate the pathogenesis of psoriatic diseases by determining the differences in metabolomic profiles among psoriasis patients...

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Armstrong AW, Wu J, Johnson MA, et al. Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. F1000Res. 2014;3:248doi: 10.12688/f1000research.4709.1.
Armstrong, A. W., Wu, J., Johnson, M. A., Grapov, D., Azizi, B., Dhillon, J., & Fiehn, O. (2014). Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. F1000Research, 3248. https://doi.org/10.12688/f1000research.4709.1
Armstrong, April W, et al. "Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis." F1000Research vol. 3 (2014): 248. doi: https://doi.org/10.12688/f1000research.4709.1
Armstrong AW, Wu J, Johnson MA, Grapov D, Azizi B, Dhillon J, Fiehn O. Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. F1000Res. 2014 Oct 21;3:248. doi: 10.12688/f1000research.4709.1. eCollection 2014. PMID: 25580230; PMCID: PMC4288418.
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Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo.

Clinical cancer research : an official journal of the American Association for Cancer Research

Ludden LK, Strong JM, Kohn EC, Collins JM.
PMID: 9815997
Clin Cancer Res. 1995 Apr;1(4):399-405.

Metabolism of a new antitumor agent, CAI (NSC 609974), was investigated in human liver tissue in vitro and in plasma and urine of patients receiving CAI. Metabolites identified by HPLC following C-labeled CAI incubation with human liver microsomes and...

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Ludden LK, Strong JM, Kohn EC, et al. Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo. Clin Cancer Res. 1995;1(4):399-405
Ludden, L. K., Strong, J. M., Kohn, E. C., & Collins, J. M. (1995). Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research, 1(4), 399-405.
Ludden, et al. "Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 1,4 (1995): 399-405.
Ludden LK, Strong JM, Kohn EC, Collins JM. Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo. Clin Cancer Res. 1995 Apr;1(4):399-405. PMID: 9815997.
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Anticancer therapy using glucuronate modified long-circulating liposomes.

Advanced drug delivery reviews

Oku N.
PMID: 10837780
Adv Drug Deliv Rev. 1999 Nov 10;40(1):63-73. doi: 10.1016/s0169-409x(99)00040-x.

Since conventional liposomes tend to be trapped by the reticuroendothelial systems (RES), their use as drug carriers is limited when the targets are not RES cells. Therefore, many attempts have been made to avoid the RES-trapping of liposomes. Favorable...

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Oku N. Anticancer therapy using glucuronate modified long-circulating liposomes. Adv Drug Deliv Rev. 1999;40(1):63-73doi: 10.1016/s0169-409x(99)00040-x.
Oku, N. (1999). Anticancer therapy using glucuronate modified long-circulating liposomes. Advanced drug delivery reviews, 40(1), 63-73. https://doi.org/10.1016/s0169-409x(99)00040-x
Oku. "Anticancer therapy using glucuronate modified long-circulating liposomes." Advanced drug delivery reviews vol. 40,1 (1999): 63-73. doi: https://doi.org/10.1016/s0169-409x(99)00040-x
Oku N. Anticancer therapy using glucuronate modified long-circulating liposomes. Adv Drug Deliv Rev. 1999 Nov 10;40(1):63-73. doi: 10.1016/s0169-409x(99)00040-x. PMID: 10837780.
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Ion-pair RP-HPLC determination of sugars, amino sugars, and uronic acids after derivatization with p-aminobenzoic acid.

Analytical chemistry

Meyer A, Raba C, Fischer K.
PMID: 11403275
Anal Chem. 2001 Jun 01;73(11):2377-82. doi: 10.1021/ac001402s.

A new, selective, and sensitive ion-pair RP-HPLC method for the simultaneous determination of three classes of natural organic compounds, i.e., carbohydrates, amino sugars, and uronic acids, in environmental samples is presented. p-Aminobenzoic acid is used for precolumn derivatization of...

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Meyer A, Raba C, Fischer K. Ion-pair RP-HPLC determination of sugars, amino sugars, and uronic acids after derivatization with p-aminobenzoic acid. Anal Chem. 2001;73(11):2377-82doi: 10.1021/ac001402s.
Meyer, A., Raba, C., & Fischer, K. (2001). Ion-pair RP-HPLC determination of sugars, amino sugars, and uronic acids after derivatization with p-aminobenzoic acid. Analytical chemistry, 73(11), 2377-82. https://doi.org/10.1021/ac001402s
Meyer, A, et al. "Ion-pair RP-HPLC determination of sugars, amino sugars, and uronic acids after derivatization with p-aminobenzoic acid." Analytical chemistry vol. 73,11 (2001): 2377-82. doi: https://doi.org/10.1021/ac001402s
Meyer A, Raba C, Fischer K. Ion-pair RP-HPLC determination of sugars, amino sugars, and uronic acids after derivatization with p-aminobenzoic acid. Anal Chem. 2001 Jun 01;73(11):2377-82. doi: 10.1021/ac001402s. PMID: 11403275.
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