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Showing 1 to 12 of 1439 entries
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Numerical Model to Characterize the Size Increase of Combination Drug and Hygroscopic Excipient Nanoparticle Aerosols.

Aerosol science and technology : the journal of the American Association for Aerosol Research

Longest PW, Hindle M.
PMID: 21804683
Aerosol Sci Technol. 2011 Jan 01;45(7):884-899. doi: 10.1080/02786826.2011.566592.

Enhanced excipient growth is a newly proposed respiratory delivery strategy in which submicrometer or nanometer particles composed of a drug and hygroscopic excipient are delivered to the airways in order to minimize extrathoracic depositional losses and maximize lung retention....

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Longest PW, Hindle M. Numerical Model to Characterize the Size Increase of Combination Drug and Hygroscopic Excipient Nanoparticle Aerosols. Aerosol Sci Technol. 2011;45(7):884-899doi: 10.1080/02786826.2011.566592.
Longest, P. W., & Hindle, M. (2011). Numerical Model to Characterize the Size Increase of Combination Drug and Hygroscopic Excipient Nanoparticle Aerosols. Aerosol science and technology : the journal of the American Association for Aerosol Research, 45(7), 884-899. https://doi.org/10.1080/02786826.2011.566592
Longest, P Worth, and Hindle, Michael. "Numerical Model to Characterize the Size Increase of Combination Drug and Hygroscopic Excipient Nanoparticle Aerosols." Aerosol science and technology : the journal of the American Association for Aerosol Research vol. 45,7 (2011): 884-899. doi: https://doi.org/10.1080/02786826.2011.566592
Longest PW, Hindle M. Numerical Model to Characterize the Size Increase of Combination Drug and Hygroscopic Excipient Nanoparticle Aerosols. Aerosol Sci Technol. 2011 Jan 01;45(7):884-899. doi: 10.1080/02786826.2011.566592. PMID: 21804683; PMCID: PMC3143486.
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A critical review of brand and generic alendronate for the treatment of osteoporosis.

SpringerPlus

Brown JP, Davison KS, Olszynski WP, Beattie KA, Adachi JD.
PMID: 25674402
Springerplus. 2013 Oct 21;2:550. doi: 10.1186/2193-1801-2-550. eCollection 2013.

OBJECTIVE: Compare in vitro and in vivo characteristics and clinical outcomes of brand and generic alendronate.RESEARCH DESIGN AND METHODS: Relevant search terms were input into Medline ("alendronate" AND "generic" up to August 5, 2013) and any abstracts deemed possibly...

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Brown JP, Davison KS, Olszynski WP, et al. A critical review of brand and generic alendronate for the treatment of osteoporosis. Springerplus. 2013;2:550doi: 10.1186/2193-1801-2-550.
Brown, J. P., Davison, K. S., Olszynski, W. P., Beattie, K. A., & Adachi, J. D. (2013). A critical review of brand and generic alendronate for the treatment of osteoporosis. SpringerPlus, 2550. https://doi.org/10.1186/2193-1801-2-550
Brown, Jacques P, et al. "A critical review of brand and generic alendronate for the treatment of osteoporosis." SpringerPlus vol. 2 (2013): 550. doi: https://doi.org/10.1186/2193-1801-2-550
Brown JP, Davison KS, Olszynski WP, Beattie KA, Adachi JD. A critical review of brand and generic alendronate for the treatment of osteoporosis. Springerplus. 2013 Oct 21;2:550. doi: 10.1186/2193-1801-2-550. eCollection 2013. PMID: 25674402; PMCID: PMC4320211.
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To study the influence of different grades of Ethylcellulose ether derivative polymer Ethocel® and co-excipient on drug release profile of controlled release matrix tablet of acarbose.

Pakistan journal of pharmaceutical sciences

Mehsud S, Rauf M, Obaidullah -, Khan KA, Khan GM.
PMID: 26687743
Pak J Pharm Sci. 2015 Nov;28(6):2259-65.

The aim of the study presented is to formulate and evaluate Acarbose controlled release matrix tablets by means of different grades of polymer Ethocel and different co-excipients with the intention to see their effects on drug release profile during...

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Mehsud S, Rauf M, Obaidullah -, et al. To study the influence of different grades of Ethylcellulose ether derivative polymer Ethocel® and co-excipient on drug release profile of controlled release matrix tablet of acarbose. Pak J Pharm Sci. 2015;28(6):2259-65
Mehsud, S., Rauf, M., Obaidullah, -., Khan, K. A., & Khan, G. M. (2015). To study the influence of different grades of Ethylcellulose ether derivative polymer Ethocel® and co-excipient on drug release profile of controlled release matrix tablet of acarbose. Pakistan journal of pharmaceutical sciences, 28(6), 2259-65.
Mehsud, Saifullah, et al. "To study the influence of different grades of Ethylcellulose ether derivative polymer Ethocel® and co-excipient on drug release profile of controlled release matrix tablet of acarbose." Pakistan journal of pharmaceutical sciences vol. 28,6 (2015): 2259-65.
Mehsud S, Rauf M, Obaidullah -, Khan KA, Khan GM. To study the influence of different grades of Ethylcellulose ether derivative polymer Ethocel® and co-excipient on drug release profile of controlled release matrix tablet of acarbose. Pak J Pharm Sci. 2015 Nov;28(6):2259-65. PMID: 26687743.
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Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics.

Drug delivery and translational research

Chi A, Curi S, Clayton K, Luciano D, Klauber K, Alexander-Katz A, D'hers S, Elman NM.
PMID: 25787065
Drug Deliv Transl Res. 2014 Aug;4(4):320-33. doi: 10.1007/s13346-014-0198-7.

Rapid Reconstitution Packages (RRPs) are portable platforms that integrate microfluidics for rapid reconstitution of lyophilized drugs. Rapid reconstitution of lyophilized drugs using standard vials and syringes is an error-prone process. RRPs were designed using computational fluid dynamics (CFD) techniques...

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Chi A, Curi S, Clayton K, et al. Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics. Drug Deliv Transl Res. 2014;4(4):320-33doi: 10.1007/s13346-014-0198-7.
Chi, A., Curi, S., Clayton, K., Luciano, D., Klauber, K., Alexander-Katz, A., D'hers, S., & Elman, N. M. (2014). Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics. Drug delivery and translational research, 4(4), 320-33. https://doi.org/10.1007/s13346-014-0198-7
Chi, Albert, et al. "Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics." Drug delivery and translational research vol. 4,4 (2014): 320-33. doi: https://doi.org/10.1007/s13346-014-0198-7
Chi A, Curi S, Clayton K, Luciano D, Klauber K, Alexander-Katz A, D'hers S, Elman NM. Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics. Drug Deliv Transl Res. 2014 Aug;4(4):320-33. doi: 10.1007/s13346-014-0198-7. PMID: 25787065.
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Role of Components in the Formation of Self-microemulsifying Drug Delivery Systems.

Indian journal of pharmaceutical sciences

Gurram AK, Deshpande PB, Kar SS, Nayak UY, Udupa N, Reddy MS.
PMID: 26180269
Indian J Pharm Sci. 2015 May-Jun;77(3):249-57. doi: 10.4103/0250-474x.159596.

Pharmaceutical research is focused in designing novel drug delivery systems to improve the bioavailability of poorly water soluble drugs. Self-microemulsifying drug delivery systems, one among the lipid-based dosage forms were proven to be promising in improving the oral bioavailability...

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Gurram AK, Deshpande PB, Kar SS, et al. Role of Components in the Formation of Self-microemulsifying Drug Delivery Systems. Indian J Pharm Sci. 2015;77(3):249-57doi: 10.4103/0250-474x.159596.
Gurram, A. K., Deshpande, P. B., Kar, S. S., Nayak, U. Y., Udupa, N., & Reddy, M. S. (2015). Role of Components in the Formation of Self-microemulsifying Drug Delivery Systems. Indian journal of pharmaceutical sciences, 77(3), 249-57. https://doi.org/10.4103/0250-474x.159596
Gurram, A K, et al. "Role of Components in the Formation of Self-microemulsifying Drug Delivery Systems." Indian journal of pharmaceutical sciences vol. 77,3 (2015): 249-57. doi: https://doi.org/10.4103/0250-474x.159596
Gurram AK, Deshpande PB, Kar SS, Nayak UY, Udupa N, Reddy MS. Role of Components in the Formation of Self-microemulsifying Drug Delivery Systems. Indian J Pharm Sci. 2015 May-Jun;77(3):249-57. doi: 10.4103/0250-474x.159596. PMID: 26180269; PMCID: PMC4502138.
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Three cases of anaphylaxis following injection of a depot corticosteroid with evidence of IgE sensitization to macrogols rather than the active steroid.

Clinical and translational allergy

Brandt N, Garvey LH, Bindslev-Jensen U, Kjaer HF, Bindslev-Jensen C, Mortz CG.
PMID: 28078080
Clin Transl Allergy. 2017 Jan 10;7:2. doi: 10.1186/s13601-016-0138-3. eCollection 2017.

We present three cases with anaphylaxis after injection of a depot corticosteroid. First, the steroid was suspected as the elicitor, but after evaluation the excipient macrogol was found to be the elicitor. One of the patients had reactions to...

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Brandt N, Garvey LH, Bindslev-Jensen U, et al. Three cases of anaphylaxis following injection of a depot corticosteroid with evidence of IgE sensitization to macrogols rather than the active steroid. Clin Transl Allergy. 2017;7:2doi: 10.1186/s13601-016-0138-3.
Brandt, N., Garvey, L. H., Bindslev-Jensen, U., Kjaer, H. F., Bindslev-Jensen, C., & Mortz, C. G. (2017). Three cases of anaphylaxis following injection of a depot corticosteroid with evidence of IgE sensitization to macrogols rather than the active steroid. Clinical and translational allergy, 72. https://doi.org/10.1186/s13601-016-0138-3
Brandt, Nicolaj, et al. "Three cases of anaphylaxis following injection of a depot corticosteroid with evidence of IgE sensitization to macrogols rather than the active steroid." Clinical and translational allergy vol. 7 (2017): 2. doi: https://doi.org/10.1186/s13601-016-0138-3
Brandt N, Garvey LH, Bindslev-Jensen U, Kjaer HF, Bindslev-Jensen C, Mortz CG. Three cases of anaphylaxis following injection of a depot corticosteroid with evidence of IgE sensitization to macrogols rather than the active steroid. Clin Transl Allergy. 2017 Jan 10;7:2. doi: 10.1186/s13601-016-0138-3. eCollection 2017. PMID: 28078080; PMCID: PMC5223300.
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A comparative study on the physicochemical and biological stability of IgG1 and monoclonal antibodies during spray drying process.

Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences

Ramezani V, Vatanara A, Najafabadi AR, Shokrgozar MA, Khabiri A, Seyedabadi M.
PMID: 24641877
Daru. 2014 Mar 18;22(1):31. doi: 10.1186/2008-2231-22-31.

BACKGROUND: The main concern in formulation of antibodies is the intrinsic instability of these labile compounds. To evaluate the physicochemical stability of antibody in dry powder formulations, physical stability of IgG1 and a monoclonal antibody (trastuzumab) during the spray...

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Ramezani V, Vatanara A, Najafabadi AR, et al. A comparative study on the physicochemical and biological stability of IgG1 and monoclonal antibodies during spray drying process. Daru. 2014;22(1):31doi: 10.1186/2008-2231-22-31.
Ramezani, V., Vatanara, A., Najafabadi, A. R., Shokrgozar, M. A., Khabiri, A., & Seyedabadi, M. (2014). A comparative study on the physicochemical and biological stability of IgG1 and monoclonal antibodies during spray drying process. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 22(1), 31. https://doi.org/10.1186/2008-2231-22-31
Ramezani, Vahid, et al. "A comparative study on the physicochemical and biological stability of IgG1 and monoclonal antibodies during spray drying process." Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences vol. 22,1 (2014): 31. doi: https://doi.org/10.1186/2008-2231-22-31
Ramezani V, Vatanara A, Najafabadi AR, Shokrgozar MA, Khabiri A, Seyedabadi M. A comparative study on the physicochemical and biological stability of IgG1 and monoclonal antibodies during spray drying process. Daru. 2014 Mar 18;22(1):31. doi: 10.1186/2008-2231-22-31. PMID: 24641877; PMCID: PMC3972992.
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Preparation and Evaluation of Valsartan Liquid Filling Formulations for Soft Gels.

Journal of pharmaceutics

Sanaboina J, Maheswari KM, Sunkara S, Deekonda S, Nalluri BN.
PMID: 26555979
J Pharm (Cairo). 2013;2013:418346. doi: 10.1155/2013/418346. Epub 2013 Jan 17.

The present investigation includes the preparation of liquid filling formulations for soft gels using an antihypertensive drug, valsartan (VAL), in order to improve its dissolution properties and thereby its bioavailability. Formulations were prepared using excipients like polyethylene glycol 400...

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Sanaboina J, Maheswari KM, Sunkara S, et al. Preparation and Evaluation of Valsartan Liquid Filling Formulations for Soft Gels. J Pharm (Cairo). 2013;2013:418346doi: 10.1155/2013/418346.
Sanaboina, J., Maheswari, K. M., Sunkara, S., Deekonda, S., & Nalluri, B. N. (2013). Preparation and Evaluation of Valsartan Liquid Filling Formulations for Soft Gels. Journal of pharmaceutics, 2013418346. https://doi.org/10.1155/2013/418346
Sanaboina, Jyothi, et al. "Preparation and Evaluation of Valsartan Liquid Filling Formulations for Soft Gels." Journal of pharmaceutics vol. 2013 (2013): 418346. doi: https://doi.org/10.1155/2013/418346
Sanaboina J, Maheswari KM, Sunkara S, Deekonda S, Nalluri BN. Preparation and Evaluation of Valsartan Liquid Filling Formulations for Soft Gels. J Pharm (Cairo). 2013;2013:418346. doi: 10.1155/2013/418346. Epub 2013 Jan 17. PMID: 26555979; PMCID: PMC4590804.
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Recently Investigated Natural Gums and Mucilages as Pharmaceutical Excipients: An Overview.

Journal of pharmaceutics

Choudhary PD, Pawar HA.
PMID: 26556189
J Pharm (Cairo). 2014;2014:204849. doi: 10.1155/2014/204849. Epub 2014 Apr 07.

Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms to fulfil specific functions and in some cases they directly or indirectly influence the extent and/or rate of drug release and drug absorption. Recent...

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Choudhary PD, Pawar HA. Recently Investigated Natural Gums and Mucilages as Pharmaceutical Excipients: An Overview. J Pharm (Cairo). 2014;2014:204849doi: 10.1155/2014/204849.
Choudhary, P. D., & Pawar, H. A. (2014). Recently Investigated Natural Gums and Mucilages as Pharmaceutical Excipients: An Overview. Journal of pharmaceutics, 2014204849. https://doi.org/10.1155/2014/204849
Choudhary, Pritam Dinesh, and Pawar, Harshal Ashok. "Recently Investigated Natural Gums and Mucilages as Pharmaceutical Excipients: An Overview." Journal of pharmaceutics vol. 2014 (2014): 204849. doi: https://doi.org/10.1155/2014/204849
Choudhary PD, Pawar HA. Recently Investigated Natural Gums and Mucilages as Pharmaceutical Excipients: An Overview. J Pharm (Cairo). 2014;2014:204849. doi: 10.1155/2014/204849. Epub 2014 Apr 07. PMID: 26556189; PMCID: PMC4590793.
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Formulation and evaluation of liquisolid compacts for olmesartan medoxomil.

Journal of drug delivery

Prajapati ST, Bulchandani HH, Patel DM, Dumaniya SK, Patel CN.
PMID: 24232077
J Drug Deliv. 2013;2013:870579. doi: 10.1155/2013/870579. Epub 2013 Oct 21.

Olmesartan medoxomil is an angiotensin type II receptor blocker, antihypertensive agent, administered orally. It is highly lipophilic (log P 5.5) and a poorly water-soluble drug with absolute bioavailability of 26%. The poor dissolution rate of water-insoluble drugs is still...

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Prajapati ST, Bulchandani HH, Patel DM, et al. Formulation and evaluation of liquisolid compacts for olmesartan medoxomil. J Drug Deliv. 2013;2013:870579doi: 10.1155/2013/870579.
Prajapati, S. T., Bulchandani, H. H., Patel, D. M., Dumaniya, S. K., & Patel, C. N. (2013). Formulation and evaluation of liquisolid compacts for olmesartan medoxomil. Journal of drug delivery, 2013870579. https://doi.org/10.1155/2013/870579
Prajapati, Shailesh T, et al. "Formulation and evaluation of liquisolid compacts for olmesartan medoxomil." Journal of drug delivery vol. 2013 (2013): 870579. doi: https://doi.org/10.1155/2013/870579
Prajapati ST, Bulchandani HH, Patel DM, Dumaniya SK, Patel CN. Formulation and evaluation of liquisolid compacts for olmesartan medoxomil. J Drug Deliv. 2013;2013:870579. doi: 10.1155/2013/870579. Epub 2013 Oct 21. PMID: 24232077; PMCID: PMC3818897.
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Development of novel multifunction directly compressible co-processed excipient by melt granulation technique.

International journal of pharmaceutical investigation

Garg N, Pandey P, Kaushik D, Dureja H.
PMID: 26682197
Int J Pharm Investig. 2015 Oct-Dec;5(4):266-74. doi: 10.4103/2230-973X.167692.

INTRODUCTION: The objective of the present investigation was to develop a novel multifunctional directly compressible co-processed excipient consisting of dibasic calcium phosphate anhydrous, polyethylene glycol 4000 (PEG 4000) and crospovidone using Box-Behnken design.MATERIALS AND METHODS: The technique of melt...

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Garg N, Pandey P, Kaushik D, et al. Development of novel multifunction directly compressible co-processed excipient by melt granulation technique. Int J Pharm Investig. 2015;5(4):266-74doi: 10.4103/2230-973X.167692.
Garg, N., Pandey, P., Kaushik, D., & Dureja, H. (2015). Development of novel multifunction directly compressible co-processed excipient by melt granulation technique. International journal of pharmaceutical investigation, 5(4), 266-74. https://doi.org/10.4103/2230-973X.167692
Garg, Nidhi, et al. "Development of novel multifunction directly compressible co-processed excipient by melt granulation technique." International journal of pharmaceutical investigation vol. 5,4 (2015): 266-74. doi: https://doi.org/10.4103/2230-973X.167692
Garg N, Pandey P, Kaushik D, Dureja H. Development of novel multifunction directly compressible co-processed excipient by melt granulation technique. Int J Pharm Investig. 2015 Oct-Dec;5(4):266-74. doi: 10.4103/2230-973X.167692. PMID: 26682197; PMCID: PMC4675008.
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Stabilisation of metastable polymorphs: the case of paracetamol form III.

Chemical communications (Cambridge, England)

Telford R, Seaton CC, Clout A, Buanz A, Gaisford S, Williams GR, Prior TJ, Okoye CH, Munshi T, Scowen IJ.
PMID: 27510730
Chem Commun (Camb). 2016 Oct 18;52(81):12028-12031. doi: 10.1039/c6cc05006a. Epub 2016 Aug 11.

The design of a melt synthesis of the first air-stable formulation of the metastable form III of paracetamol is derived from thermo-spectroscopic and thermo-diffraction experiments. Melt crystallisation in the presence of β-1,4-saccharides produces form III selectively and the excipients...

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Telford R, Seaton CC, Clout A, et al. Stabilisation of metastable polymorphs: the case of paracetamol form III. Chem Commun (Camb). 2016;52(81):12028-12031doi: 10.1039/c6cc05006a.
Telford, R., Seaton, C. C., Clout, A., Buanz, A., Gaisford, S., Williams, G. R., Prior, T. J., Okoye, C. H., Munshi, T., & Scowen, I. J. (2016). Stabilisation of metastable polymorphs: the case of paracetamol form III. Chemical communications (Cambridge, England), 52(81), 12028-12031. https://doi.org/10.1039/c6cc05006a
Telford, Richard, et al. "Stabilisation of metastable polymorphs: the case of paracetamol form III." Chemical communications (Cambridge, England) vol. 52,81 (2016): 12028-12031. doi: https://doi.org/10.1039/c6cc05006a
Telford R, Seaton CC, Clout A, Buanz A, Gaisford S, Williams GR, Prior TJ, Okoye CH, Munshi T, Scowen IJ. Stabilisation of metastable polymorphs: the case of paracetamol form III. Chem Commun (Camb). 2016 Oct 18;52(81):12028-12031. doi: 10.1039/c6cc05006a. Epub 2016 Aug 11. PMID: 27510730.
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Showing 1 to 12 of 1439 entries