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Diversity of properties among catalases

diversity

[No authors listed]
GSID: hIl8EWmssJsJ
J Switala, PC Loewen - Archives of biochemistry and biophysics, 2002 - Elsevier

Catalases from 16 different organisms including representatives from all three phylogenetic clades were purified and characterized to provide a comparative picture of their respective properties. Collectively the enzymes presented a diverse range of activities and properties. …

R plasmid gene dosage effects in Escherichia coli K-12: copy mutants of the R plasmid R1drd-19

k-12

Uhlin BE.
GSID: t7a9IJEQjIIJ
BE Uhlin, K Nordström - Plasmid, 1977 - Elsevier

… coli K-12 strain EC1005. The bacteria were grown logarithmically in LB medium and at a cell … Effect of R-factor-mediated drug-metabolizing enzymes on survival of Escherichia co/i K-12 in … Mutations in Escherichia coli K-12 decreasing the rate...

Revealing Nature's Cellulase Diversity: The Digestion Mechanism of Caldicellulosiruptor bescii CelA

diversity

Brunecky R, Alahuhta M, Xu Q, Donohoe BS.
GSID: IieGVQ6oYn8J
R Brunecky, M Alahuhta, Q Xu, BS Donohoe… - Science, 2013 - science.org

Most fungi and bacteria degrade plant cell walls by secreting free, complementary enzymes that hydrolyze cellulose; however, some bacteria use large enzymatic assemblies called cellulosomes, which recruit complementary enzymes to protein scaffolds. The thermophilic …

Molybdenum and tungsten enzymes: from biology to chemistry and back

pipeline programs

Maia LB, Moura JJG.
GSID: KE3IhFtuDr0J
JJG Moura, PV Bernhardt, LB Maia… - JBIC Journal of Biological …, 2015 - Springer

© SBIC 2015 conference themes have broadened to include contributors from nitrogenase field, where Mo is associated with Fe, in the FeMoco cluster and the papers in this issue …

Extending the application of biocatalysis to meet the challenges of drug development

Build and Broaden 3.0 AND Program Evaluation

Kumar R.
GSID: MtNdMtCXuGYJ
PN Devine, RM Howard, R Kumar… - Nature Reviews …, 2018 - nature.com

The pharmaceutical industry, driven by an increasing need to deliver new and more effective medicines to patients, is increasingly turning to the use of engineered biocatalysts for both lead generation of active compounds and the sustainable manufacture of active...

Electrochemical and in situ IR characterization of PtRu catalysts for complete oxidation of ethylene glycol and glycerol

Louis Stokes Alliances for Minority Participation AND Program Evaluation

Atanassov P.
GSID: ovVlT2FyXxsJ
A Falase, K Garcia, C Lau, P Atanassov - Electrochemistry communications, 2011 - Elsevier

Unsupported nanostructured PtRu electrocatalysts were synthesized using a spray pyrolysis process with varying atomic compositions. A ruthenium rich and platinum rich PtRu were compared to supported E-Tek PtRu on Vulcan XC-72 at a pH range from 5 to 8...

Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer

Build and Broaden 3.0 AND Program Evaluation

Bruno R, Hille D, Riva A.
GSID: cN3u3FPD-8gJ
R Bruno, D Hille, A Riva, N Vivier… - Journal of clinical …, 1998 - Citeseer

Conclusion: First-course docetaxel PK is a predictor of first-course hematologic toxicity, but also of fluid retention, which is cumulative in nature. Patients with elevated hepatic enzymes have a 27% reduction in docetaxel CL and are at a higher risk...

Role of drug absorption in the pharmacokinetics of therapeutic interventions for stroke

Stem education interventions

Conrado DJ, Gonzalez D.
GSID: jK3cVc-0N7gJ
DJ Conrado, D Gonzalez… - Annals of the New York …, 2010 - Wiley Online Library

Absorption is a critical component of the pharmacokinetics for solid dosage forms administered orally. Many barriers must be overcome in order for a drug molecule to reach its effect site. To effectively address each of these barriers, drug‐specific properties,...

Regulation of methionine biosynthesis in Escherichia coli: mapping of the metJ locus and properties of a metJ plus-metJ minus diploid.

Proceedings of the National Academy of Sciences of the United States of America

Su CH, Greene RC.
PMID: 5277087
Proc Natl Acad Sci U S A. 1971 Feb;68(2):367-71. doi: 10.1073/pnas.68.2.367.
Free PMC Article

MetJ(-) mutants of Escherichia coli have elevated nonrepressible levels of the enzymes of methionine biosynthesis and S-adenosylmethionine synthetase (ATP:L-methionine S-adenosyltransferase, EC 2.5.1.6). In E. coli, as in Salmonella typhimurium, the metJ locus is close to metB (95% cotransduction of...

Alterations in glycosyltransferase activity in human colon cancer.

Journal of the National Cancer Institute

LaMont JT, Isselbacher KJ.
PMID: 1113312
J Natl Cancer Inst. 1975 Jan;54(1):53-56. doi: 10.1093/jnci/54.1.53.

Glycosyltransferase enzymes were measured in homogenates of normal and neoplastic colon epithelium. The levels for exogenous galactosyltransferase and fucosyltransferase and endogenous N-acetylglucosaminyl-transferase were higher in the normal tissue. The levels for exogenous and endogenous sialyltransferase and endogenous galactosyltransferase and...

Experimental Investigations on the Effects of Carbon and Nitrogen Sources on Concomitant Amylase and Polygalacturonase Production by Trichoderma viride BITRS-1001 in Submerged Fermentation.

Biotechnology research international

Juwon AD, Emmanuel OF.
PMID: 22919504
Biotechnol Res Int. 2012;2012:904763. doi: 10.1155/2012/904763. Epub 2012 Jul 15.

The paper investigates the effects of different commercial carbon and nitrogen sources on the concomitant synthesis of amylase and polygalacturonase enzymes with the aim of optimizing them for maximal enzyme production. The microorganism used in this work was the...

The effects of oral hydrolytic enzymes and flavonoids on inflammatory markers and coagulation after marathon running: study protocol for a randomized, double-blind, placebo-controlled trial.

BMC sports science, medicine & rehabilitation

Grabs V, Nieman DC, Haller B, Halle M, Scherr J.
PMID: 24559067
BMC Sports Sci Med Rehabil. 2014 Feb 22;6(1):8. doi: 10.1186/2052-1847-6-8.

BACKGROUND: Regular moderate intensity physical activity positively influences the immune system with a lower incidence of upper respiratory tract infections (URTI) and lower levels of pro-inflammatory markers. However, marathon running due to its strenuous and prolonged nature results in...

Showing 1 to 12 of 40378 entries