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[Drug administration schedule of anti-ulcer agents to prevent recurrence of peptic ulcer; combination therapy of inhibitors of attacking factors and synergistic drugs for protective factors in peptic ulcer--selection of drug combinations and clinical efficacy].

Nihon rinsho. Japanese journal of clinical medicine

Sakai M.
PMID: 3373745
Nihon Rinsho. 1988 Jan;46(1):124-32.

No abstract available.

[The clinical significance of the quantity of tubercle bacilli in the sputum during tuberculostatic treatment. II. The effect of 2 and 3-drug combinations on the tempo of decrease of the quantity of bacteria].

Beitrage zur Klinik und Erforschung der Tuberkulose und der Lungenkrankheiten

Seri I.
PMID: 4957553
Beitr Klin Erforsch Tuberk Lungenkr. 1965 Dec 30;131(5):368-74.

No abstract available.

Age and dose of chemotherapy as major prognostic factors in a trial of adjuvant therapy of osteosarcoma combining two alternating drug combinations and early prophylactic lung irradiation. French Bone Tumor Study Group.


[No authors listed]
PMID: 3125957
Cancer. 1988 Apr 01;61(7):1304-11. doi: 10.1002/1097-0142(19880401)61:7<1304::aid-cncr2820610705>;2-i.

From January 1978 to May 1983, 41 patients with primary high-grade osteogenic osteosarcoma of a limb were treated with a combination of intensive chemotherapy and prophylactic lung irradiation (PLI) intercalated between the first two cycles of chemotherapy. The primary...

The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate.

Annals of tropical medicine and parasitology

Peters W, Stewart LB, Robinson BL.
PMID: 16004705
Ann Trop Med Parasitol. 2005 Jul;99(5):457-72. doi: 10.1179/136485905X51274.

Resistance is readily produced in rodent malaria using the single-dose, '2%-relapse technique' (2%RT) against the individual compounds chlorproguanil (CPG), chlorcycloguanil (CCG), cycloguanil, dapsone (DDS) and artesunate (ASN). Using the '4-day test', a low level of synergism or a simple...

Phase II studies of drug combinations in advanced pancreatic carcinoma: fluorouracil plus doxorubicin plus mitomycin C and two regimens of streptozotocin plus mitomycin C plus fluorouracil. The Gastrointestinal Tumor Study Group.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

[No authors listed]
PMID: 2946815
J Clin Oncol. 1986 Dec;4(12):1794-8. doi: 10.1200/JCO.1986.4.12.1794.

One hundred thirty-three patients with advanced pancreatic adenocarcinoma and measurable disease were treated with 5-fluorouracil (5-FU) plus doxorubicin plus mitomycin C (FAM), streptozotocin plus mitomycin C plus 5-FU (SMF) in the regimen originally reported, and streptozotocin plus mitomycin C...

Chemotherapy of advanced colorectal carcinoma: fluorouracil alone vs. two drug combinations using fluorouracil, hydroxyurea, semustine, dacarbazine, razoxane, and mitomycin. A phase III trial by the Eastern Cooperative Oncology Group (EST: 1278).

American journal of clinical oncology

Engstrom PF, MacIntyre JM, Mittelman A, Klaassen DJ.
PMID: 6377866
Am J Clin Oncol. 1984 Aug;7(4):313-8.

Patients with advanced colorectal cancer and no prior chemotherapy were randomized to six treatment regimens: A) fluorouracil (FU) alone; B) FU + hydroxyurea (HU); C) semustine (SE) + dacarbazine (DA); D) FU + HU alternating with SE + DA;...

An update of two randomized trials in previously untreated multiple myeloma comparing melphalan and prednisone versus three- and five-drug combinations: an Argentine Group for the Treatment of Acute Leukemia Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Pavlovsky S, Corrado C, Santarelli MT, Saslavsky J, Cavagnaro F, Palau M, de Tezanos Pinto M, Huberman A, Lein JM.
PMID: 3284974
J Clin Oncol. 1988 May;6(5):769-75. doi: 10.1200/JCO.1988.6.5.769.

An update of two consecutive randomized studies in previously untreated multiple myeloma was performed. The first study (10-M-73) began in 1973; 150 patients were treated with melphalan and prednisone (MP) or semustine, cyclophosphamide, and prednisone (MeCP). In a second...

A comparative study of a BCNU containing 4-drug program versus MOPP versus 3-drug combinations in advanced Hodgkin's disease: a cooperative study by the Cancer and Leukemia Group B.


Nissen NI, Pajak TF, Glidewell O, Pedersen-Bjergaard J, Stutzman L, Falkson G, Cuttner J, Blom J, Leone L, Sawitsky A, Coleman M, Haurani F, Spurr CL, Harley JB, Seligman B, Cornell C, Henry P, Senn HJ, Brunner K, Martz G, Maurice P, Bank A, Shapiro L, James GW, Holland JF.
PMID: 367570
Cancer. 1979 Jan;43(1):31-40. doi: 10.1002/1097-0142(197901)43:1<31::aid-cncr2820430104>;2-y.

A prospective randomized trial by CALGB examined the relative value of four chemotherapy regimens in 537 patients with stage III B and IV Hodgkin's disease. A new combination BOPP, derived by substitution of BCNU for nitrogen mustard in the...

The chemotherapy of rodent malaria. LVIII. Drug combinations to impede the selection of drug resistance, Part. 2: The new generation--artemisinin or artesunate with long-acting blood schizontocides.

Annals of tropical medicine and parasitology

Peters W, Robinson BL.
PMID: 10723521
Ann Trop Med Parasitol. 2000 Jan;94(1):23-35. doi: 10.1080/00034980057581.

The search for combinations of antimalarial drugs that will impede the selection of drug resistance, especially in Plasmodium falciparum, is currently focused on the use of a member of the artemisinin family, with a short half-life, in association with...

Systematic evaluation of rationally chosen multitargeted drug combinations: a combination of low doses of levetiracetam, atorvastatin and ceftriaxone exerts antiepileptogenic effects in a mouse model of acquired epilepsy.

Neurobiology of disease

Welzel L, Bergin DH, Schidlitzki A, Twele F, Johne M, Klein P, Löscher W.
PMID: 33347976
Neurobiol Dis. 2021 Feb;149:105227. doi: 10.1016/j.nbd.2020.105227. Epub 2020 Dec 19.

Epileptogenesis, the gradual process that leads to epilepsy after brain injury or genetic mutations, is a complex network phenomenon, involving a variety of morphological, biochemical and functional brain alterations. Although risk factors for developing epilepsy are known, there is...

Biphasic Mathematical Model of Cell-Drug Interaction That Separates Target-Specific and Off-Target Inhibition and Suggests Potent Targeted Drug Combinations for Multi-Driver Colorectal Cancer Cells.


Shen J, Li L, Yang T, Cohen PS, Sun G.
PMID: 32069833
Cancers (Basel). 2020 Feb 13;12(2). doi: 10.3390/cancers12020436.

Quantifying the response of cancer cells to a drug, and understanding the mechanistic basis of the response, are the cornerstones for anti-cancer drug discovery. Classical single target-based IC

[Alcohol, drugs and traffic laws. 2: Studies of the assessment of significant disability in automobile driving fitness caused by psychotropic drugs or alcohol and psychotropic drug combinations].

Zeitschrift fur arztliche Fortbildung

Eulitz J, Krause D, Herold C, Brier C, Koch R.
PMID: 3811420
Z Arztl Fortbild (Jena). 1986;80(19):823-6.

No abstract available.

Showing 1 to 12 of 79600 entries