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Showing 1 to 12 of 6295 entries
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Immunomodulatory effects of the botanical compound LCS101: implications for cancer treatment.

OncoTargets and therapy

Rachmut IH, Samuels N, Melnick SJ, Ramachandran C, Sharabi Y, Pavlovsky A, Maimon Y, Shoham J.
PMID: 23637542
Onco Targets Ther. 2013 Apr 24;6:437-45. doi: 10.2147/OTT.S42038. Print 2013.

OBJECTIVE: To examine the effects of LSC101, a botanical compound, on adaptive and innate immunity.MATERIALS AND METHODS: LCS101 preparations were tested for batch-to-batch consistency using high-performance liquid chromatography. T-cell activation was quantified in murine spleen cells using 3H-thymidine incorporation,...

Elimination of cancer stem-like "side population" cells in hepatoma cell lines by chinese herbal mixture "tien-hsien liquid".

Evidence-based complementary and alternative medicine : eCAM

Yao CJ, Yeh CT, Lee LM, Chuang SE, Yeh CF, Chao WJ, Lai TY, Lai GM.
PMID: 23097677
Evid Based Complement Alternat Med. 2012;2012:617085. doi: 10.1155/2012/617085. Epub 2012 Oct 14.

There are increasing pieces of evidence suggesting that the recurrence of cancer may result from a small subpopulation of cancer stem cells, which are resistant to the conventional chemotherapy and radiotherapy. We investigated the effects of Chinese herbal mixture...

Cardioprotective Effect of Dexrazoxane in Patients with HER2-Positive Breast Cancer Who Receive Anthracycline Based Adjuvant Chemotherapy Followed by Trastuzumab.

Journal of breast cancer

Kim IH, Lee JE, Youn HJ, Song BJ, Chae BJ.
PMID: 28382098
J Breast Cancer. 2017 Mar;20(1):82-90. doi: 10.4048/jbc.2017.20.1.82. Epub 2017 Mar 24.

PURPOSE: We intended to determine whether dexrazoxane (DZR) is cardioprotective during administration of adjuvant anthracycline-based chemotherapy followed by a 1-year trastuzumab treatment.METHODS: The medical records of 228 patients who underwent surgical resection and received adjuvant chemotherapy with trastuzumab for...

Efficacy and safety of traditional chemotherapies for patients with ovarian neoplasm: a network meta-analysis.

Oncotarget

Yang L, Guo G, Sun L, Li C, Zhang H.
PMID: 28938689
Oncotarget. 2017 Mar 30;8(35):59867-59877. doi: 10.18632/oncotarget.16729. eCollection 2017 Aug 29.

BACKGROUND: Ovarian neoplasm is a kind of high risky cancer among female. This paper assessed the efficacy and safety of twelve therapies and figured out the superior chemotherapeutic drug for ovarian cancer through network meta-analysis (NMA).METHOD: Eligible randomized controlled...

LncRNA plasmacytoma variant translocation 1 is an oncogene in bladder urothelial carcinoma.

Oncotarget

Liu Z, Zhang H.
PMID: 28969069
Oncotarget. 2017 Jul 26;8(38):64273-64282. doi: 10.18632/oncotarget.19604. eCollection 2017 Sep 08.

Bladder cancer (BC) is the most lethal malignant cancer of the genitourinary system, and bladder urothelial carcinoma (BUC) is the most common type of BC. The long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) is overexpressed in several...

Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative.

Cancer cell international

Reynisson J, Jaiswal JK, Barker D, D'mello SA, Denny WA, Baguley BC, Leung EY.
PMID: 26966420
Cancer Cell Int. 2016 Mar 10;16:18. doi: 10.1186/s12935-016-0293-6. eCollection 2016.

BACKGROUND: The thieno[2,3-b]pyridines were discovered by virtual high throughput screening as potential inhibitors of phospholipase C (PLC) isoforms and showed potent growth inhibitory effects in National Cancer Institute's human tumour cell line panel (NCI60). The mechanism of the anti-proliferative...

Interaction Mechanism of Doxorubicin and SWCNT: Protonation and Diameter Effects on the Drug Loading and Releasing.

RSC advances

Wang Y, Xu Z.
PMID: 26925231
RSC Adv. 2016;6(1):314-322. doi: 10.1039/C5RA20866A. Epub 2015 Dec 03.

In the present work the adsorption of doxorubicin (DOX) on the surface of single-walled carbon nanotube (SWCNT) as well as its encapsulation in SWCNT, and their dependence on the protonation of NH

The effect of a number of H9C2 rat cardiomyocytes passage on repeatability of cytotoxicity study results.

Cytotechnology

Witek P, Korga A, Burdan F, Ostrowska M, Nosowska B, Iwan M, Dudka J.
PMID: 26946144
Cytotechnology. 2016 Dec;68(6):2407-2415. doi: 10.1007/s10616-016-9957-2. Epub 2016 Mar 05.

The embryonic cardiomyocyte cell line H9C2 is commonly used in numerous in vitro studies, including cardiotoxicity analyses of new drugs. So far no results were published for studies on cell parameters variability during the cell line ageing process. For...

Cytotoxic Evaluations of Iranian Conifers on Cancer Cells.

Pharmaceutical biology

Emami SA, Sadeghi-Aliabadi H, Saeidi M, Jafarian A.
PMID: 28925830
Pharm Biol. 2005;43(4):299-304. doi: 10.1080/13880200590951676.

In this study, branchlets, fruit, or bark of Taxus baccata. L. as well as branchlets or fruits of two other species of Iranian conifers, namely, Platycladus orientalis. France and Cupressus sempervirens. L. var. horizentalis. (Mill) Gunde were collected, identified,...

PEG-polypeptide conjugated with LHRH as an efficient vehicle for targeted delivery of doxorubicin to breast cancer.

Journal of controlled release : official journal of the Controlled Release Society

Lv S, Tang Z, Li M, Song W, Chen X.
PMID: 27005267
J Control Release. 2015 Sep 10;213:e99. doi: 10.1016/j.jconrel.2015.05.165. Epub 2015 Aug 19.

No abstract available.

Metastatic extraskeletal Ewing's sarcoma treated with trabectedin: A case report.

Oncology letters

Hernando-Cubero J, Sanz-Moncasi P, Hernández-García A, Pajares-Bernard I, Martínez-Trufero J.
PMID: 27698882
Oncol Lett. 2016 Oct;12(4):2936-2941. doi: 10.3892/ol.2016.4950. Epub 2016 Aug 03.

The Ewing's sarcoma family of tumors (ESFT) comprises a number of rare malignant tumors. Standard first-line treatment for patients with these tumors includes chemotherapy with a five-drug regimen of vincristine, doxorubicin (Adriamycin

Primary Ewing sarcoma of the kidney: a case report and treatment review.

CEN case reports

Sadiq M, Ahmad I, Shuja J, Ahmad K.
PMID: 28509141
CEN Case Rep. 2017 Nov;6(2):132-135. doi: 10.1007/s13730-017-0259-0. Epub 2017 Apr 21.

Ewing sarcomas/primitive neuroectodermal tumors (ES/PNET) of the kidney are rarely found high-grade malignant tumors, offering poor prognosis. Although established treatment guidelines for ES of kidney are scarce, a multi-modality treatment approached is typically implemented. Herein, we report a 14-year-old...

Showing 1 to 12 of 6295 entries