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Showing 1 to 12 of 18 entries
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Differential inhibition by castanospermine of various insect disaccharidases.

Journal of chemical ecology

Campbell BC, Molyneux RJ, Jones KC.
PMID: 24302343
J Chem Ecol. 1987 Jul;13(7):1759-70. doi: 10.1007/BF00980216.

The indolizidine alkaloid, castanospermine (1,6,7,8-tetrahydroxy-octahydroindolizidine-a stereochemical mimic of glucose found in the Australian legumeCastanospermum australe), differentially inhibited cellobiose, lactose, maltose, sucrose, and trehalose hydrolyzing enzymes from a broad taxonomic spectrum of insects (19 species from 12 different families). It...

Impact of Yersinia enterocolitica enteritis on disaccharidase activity and small intestinal morphology in colostrum-deprived newborn piglets.

New Zealand veterinary journal

Shu D, Simpson HV, Xu RJ, Mellor DJ, Reynolds GW, Marshall RB.
PMID: 16031944
N Z Vet J. 1997 Feb;45(1):27-36. doi: 10.1080/00480169.1997.35984.

The effect of enteritis on the development of the small intestine was examined in newborn, colostrum-deprived piglets infected with a human isolate of Y. enterocolitica (serotype 0:3, biotype 4) soon after birth. The piglets were killed 3 days (n...

Hypoglycaemic effects and inhibitory effect on intestinal disaccharidases of oat beta-glucan in streptozotocin-induced diabetic mice.

Food chemistry

Dong J, Cai F, Shen R, Liu Y.
PMID: 25212338
Food Chem. 2011 Dec 01;129(3):1066-71. doi: 10.1016/j.foodchem.2011.05.076. Epub 2011 May 25.

Most physiological studies on oat beta (β)-glucan referred to attenuation of blood glucose and insulin responses in both healthy and diabetic individuals. The main purpose of this work was to evaluate the effects of oat β-glucan on glucose metabolism...

New therapeutic approaches to non-insulin-dependent diabetes mellitus.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Bloomgarden ZT.
PMID: 15251787
Endocr Pract. 1997 Sep-Oct;3(5):307-12. doi: 10.4158/EP.3.5.307.

OBJECTIVE: To review the new treatment strategies for non-insulin-dependent diabetes mellitus (NIDDM).METHODS: Various measures aimed at either increasing insulin secretion or decreasing insulin resistance are outlined. In addition, the management of obesity in patients with diabetes is discussed.RESULTS: Two...

Faecal excretion of brush border membrane enzymes in patients with Clostridium difficile diarrhoea.

Indian journal of medical microbiology

Katyal R, Vaishnavi C, Singh K.
PMID: 17657066
Indian J Med Microbiol. 2002 Oct-Dec;20(4):178-82.

PURPOSE: To look for the presence of intestinal brush border membrane (BBM) enzymes in the faecal samples of patients with Clostridium difficile association.METHODS: One hundred faecal samples were investigated for C.difficile toxin (CDT). Simultaneous assays for faecal excretion of...

The Pathophysiology of Malabsorption.

Viszeralmedizin

Keller J, Layer P.
PMID: 26288588
Viszeralmedizin. 2014 Jun;30(3):150-4. doi: 10.1159/000364794.

Physiological digestion and absorption of nutrients within the gastrointestinal tract requires a complex interaction between motor, secretory, digestive, and absorptive functions that is vulnerable to a multitude of potential disturbances which may lead to global or specific malabsorption syndromes....

Oral Administration of the Probiotic Lactobacillus casei Ameliorates Gut Morphology and Physiology in Malnourished-Giardia intestinalis-Infected BALB/c Mice.

ISRN parasitology

Shukla G, Singh S, Verma A.
PMID: 27335861
ISRN Parasitol. 2013 Sep 21;2013:762638. doi: 10.5402/2013/762638. eCollection 2013.

Malnutrition reduces the host immunity and enhances the host susceptibility to various diseases. The present study describes the effect of oral administration of probiotic Lactobacillus casei to malnourished-Giardia-infected BALB/c mice with respect to surface alterations and brush border membrane...

[Pathogenesis of rotavirus diarrhea].

Virologie (Montrouge, France)

Lorrot M, Benhamadouche-Casari H, Vasseur M.
PMID: 34479448
Virologie (Montrouge). 2005 Feb 01;9(1):9-18. doi: 10.1684/vir.2020.1281.

Rotavirus is responsible for infantile gastroenteritis and each year causes 440 000 deaths worldwide. The virus infects the mature enterocytes of the villus tip of the small intestine and induces a watery diarrhea. Diarrhea can occur with no visible...

Hypoglycemic activity of extracts of .

Journal of traditional and complementary medicine

Hsu CY, Lin GM, Chang ST.
PMID: 32695656
J Tradit Complement Med. 2019 Nov 29;10(4):389-395. doi: 10.1016/j.jtcme.2019.11.003. eCollection 2020 Jul.

No abstract available.

Jejunal perfusion of simple and conjugated folates in tropical sprue.

The Journal of clinical investigation

Corcino JJ, Reisenauer AM, Halsted CH.
PMID: 16695965
J Clin Invest. 1976 Aug;58(2):298-305. doi: 10.1172/JCI108472.

Absorption of labeled simple 3',5',9'-(3)H pteroylmonoglutamate, ([(3)H]PG-1) and conjugated pteroyl-mu[(14)C]glutamyl-gamma-hexaglutamate, ([(14)C]PG-7) folates was assessed in six patients with tropical sprue, before and after 6 mo of treatment, utilizing jejunal perfusion and urinary recovery techniques. Degradation products of [(14)C]PG-7 which...

Similarity of hydrolyzing activity of human and rat small intestinal disaccharidases.

Clinical and experimental gastroenterology

Oku T, Tanabe K, Ogawa S, Sadamori N, Nakamura S.
PMID: 21904461
Clin Exp Gastroenterol. 2011;4:155-61. doi: 10.2147/CEG.S19961. Epub 2011 Jun 27.

BACKGROUND: The purpose of this study was to clarify whether it is possible to extrapolate results from studies of the hydrolyzing activity of disaccharidases from rats to humans.MATERIALS AND METHODS: We measured disaccharidase activity in humans and rats using...

The multiple roles of sucrase-isomaltase in the intestinal physiology.

Molecular and cellular pediatrics

Gericke B, Amiri M, Naim HY.
PMID: 26812950
Mol Cell Pediatr. 2016 Dec;3(1):2. doi: 10.1186/s40348-016-0033-y. Epub 2016 Jan 26.

Osmotic diarrhea and abdominal pain in humans are oftentimes associated with carbohydrate malabsorption in the small intestine due to loss of function of microvillar disaccharidases. Disaccharidases are crucial for the digestion and the subsequent absorption of carbohydrates. This review...

Showing 1 to 12 of 18 entries