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Showing 1 to 12 of 222 entries
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Novel diet-related mouse model of colon cancer parallels human colon cancer.

World journal of gastrointestinal oncology

Prasad AR, Prasad S, Nguyen H, Facista A, Lewis C, Zaitlin B, Bernstein H, Bernstein C.
PMID: 25024814
World J Gastrointest Oncol. 2014 Jul 15;6(7):225-43. doi: 10.4251/wjgo.v6.i7.225.

AIM: To investigate the close parallels between our novel diet-related mouse model of colon cancer and human colon cancer.METHODS: Twenty-two wild-type female mice (ages 6-8 wk) were fed the standard control diet (AIN-93G) and an additional 22 female mice...

Leaf-specific pathogenesis-related 10 homolog, PgPR-10.3, shows in silico binding affinity with several biologically important molecules.

Journal of ginseng research

Han JH, Lee JH, Lee OR.
PMID: 26869835
J Ginseng Res. 2015 Oct;39(4):406-13. doi: 10.1016/j.jgr.2015.06.002. Epub 2015 Jun 19.

BACKGROUND: Pathogenesis-related 10 (PR-10) proteins are small, cytosolic proteins with a similar three-dimensional structure. Crystal structures for several PR-10 homologs have similar overall folding patterns, with an unusually large internal cavity that is a binding site for biologically important...

pH-Responsive Micelle-Based Cytoplasmic Delivery System for Induction of Cellular Immunity.

Vaccines

Yuba E, Sakaguchi N, Kanda Y, Miyazaki M, Koiwai K.
PMID: 29113042
Vaccines (Basel). 2017 Nov 04;5(4). doi: 10.3390/vaccines5040041.

(1) Background: Cytoplasmic delivery of antigens is crucial for the induction of cellular immunity, which is an important immune response for the treatment of cancer and infectious diseases. To date, fusogenic protein-incorporated liposomes and pH-responsive polymer-modified liposomes have been...

Swertianlarin, an Herbal Agent Derived from Swertia mussotii Franch, Attenuates Liver Injury, Inflammation, and Cholestasis in Common Bile Duct-Ligated Rats.

Evidence-based complementary and alternative medicine : eCAM

Zhang L, Cheng Y, Du X, Chen S, Feng X, Gao Y, Li S, Liu L, Yang M, Chen L, Peng Z, Yang Y, Luo W, Wang R, Chen W, Chai J.
PMID: 26273316
Evid Based Complement Alternat Med. 2015;2015:948376. doi: 10.1155/2015/948376. Epub 2015 Jul 27.

Swertianlarin is an herbal agent abundantly distributed in Swertia mussotii Franch, a Chinese traditional herb used for treatment of jaundice. To study the therapeutic effect of swertianlarin on cholestasis, liver injury, serum proinflammatory cytokines, and bile salt concentrations were...

Ion-selective electrodes based on molecular tweezer-type neutral carriers.

Talanta

Shim JH, Jeong IS, Lee MH, Hong HP, On JH, Kim KS, Kim HS, Kim BH, Cha GS, Nam H.
PMID: 18969404
Talanta. 2004 May 10;63(1):61-71. doi: 10.1016/j.talanta.2003.12.050.

Potentiometric properties of cholic and deoxycholic acid derivatives substituted with various ion-recognizing moieties, such as dithiocarbamate, bipyridyl, glycolic and malonic diamides, urea and thiourea, and trifluoroacetophenons (TFAP), have been studied using solvent polymeric membranes. The dithiocarbamate and bipyridyl group...

Improvement of Experimentally Induced Hepatic and Renal Disorders in Rats using Lactic Acid Bacteria-fermented Soybean Extract (BiofermenticsTM).

Evidence-based complementary and alternative medicine : eCAM

Shin R, Suzuki M, Mizutani T, Susa N.
PMID: 18955265
Evid Based Complement Alternat Med. 2009 Sep;6(3):357-63. doi: 10.1093/ecam/nem126. Epub 2007 Oct 27.

The effects of lactic acid bacteria-fermented soybean extract (Biofermentics; BF) on experimental models of hepatic and renal disorders were investigated in vivo and in vitro. In rat, hepatitis induced by feeding of deoxycholic acid (DCA, 0.5 wt/wt, n =...

Lithocholic acid-induced placental tumor necrosis factor-α upregulation and syncytiotrophoblast cell apoptosis in intrahepatic cholestasis of pregnancy.

Hepatology research : the official journal of the Japan Society of Hepatology

Du Q, Zhang Y, Pan Y, Duan T.
PMID: 23627780
Hepatol Res. 2014 May;44(5):532-41. doi: 10.1111/hepr.12150. Epub 2013 May 31.

AIM: To investigate tumor necrosis factor (TNF)-α expression and its relationship with serum bile acids in placental trophoblasts from patients with intrahepatic cholestasis of pregnancy (ICP).METHODS: Human placenta, including normal pregnancies (n = 10) and patients with ICP (n...

Fat Busters: Lipolysis for Face and Neck.

Journal of cutaneous and aesthetic surgery

Talathi A, Talathi P.
PMID: 30210208
J Cutan Aesthet Surg. 2018 Apr-Jun;11(2):67-72. doi: 10.4103/JCAS.JCAS_59_18.

Persistence and hypertrophy of fat pads particularly of the face and neck region disturb beauty proportions, thus demand treatments. Phosphatidylcholine and deoxycholic acid are the most commonly used solutions for injection lipolysis. As we stand today, sodium deoxycholate preparation...

Deoxycholic acid and l-Phenylalanine enrich their hydrogel properties when combined in a zwitterionic derivative.

Journal of colloid and interface science

Travaglini L, di Gregorio MC, Severoni E, D'Annibale A, Sennato S, Tardani F, Giustini M, Gubitosi M, Del Giudice A, Galantini L.
PMID: 31325679
J Colloid Interface Sci. 2019 Oct 15;554:453-462. doi: 10.1016/j.jcis.2019.07.019. Epub 2019 Jul 08.

HYPOTHESIS: Sodium Deoxycholate (NaDC) and Phenylalanine (Phe) are important biological hydrogelators. NaDC hydrogels form by lowering the pH or by increasing the ionic strength. Phe gels form from saturated solution by thermal induction and slow kinetics. The resulting gels...

Diversity of Bacteria Exhibiting Bile Acid-inducible 7α-dehydroxylation Genes in the Human Gut.

Computational and structural biotechnology journal

Vital M, Rud T, Rath S, Pieper DH, Schlüter D.
PMID: 31428294
Comput Struct Biotechnol J. 2019 Jul 26;17:1016-1019. doi: 10.1016/j.csbj.2019.07.012. eCollection 2019.

The secondary bile acids deoxycholic acid (DCA) and lithocholic acid (LCA), formed by gut microbiota from primary bile acids via a multi-step 7α-dehydroxylation reaction, have wide-ranging effects on host metabolism and play an important role in health and disease....

Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine.

Polymers

Yin Y, Lee JE, Kim NW, Lee JH, Lim SY, Kim ES, Park JW, Lee MS, Jeong JH.
PMID: 30960878
Polymers (Basel). 2018 Aug 27;10(9). doi: 10.3390/polym10090953.

RNA interference (RNAi), mediated by small interfering RNA (siRNA), has been considered as a potential therapeutic agent for cancer owing to its ability to suppress target genes in a sequence-specific manner. In this study, a conjugate of the low...

Interactions between fecal bacteria, bile acids and components of tomato pomace.

Food science and biotechnology

Dziedzic K, Górecka D, Szwengiel A, Michniewicz J, Drożdżyńska A, Walkowiak J.
PMID: 31093422
Food Sci Biotechnol. 2018 Dec 08;28(3):649-655. doi: 10.1007/s10068-018-0527-6. eCollection 2019 Jun.

The tomato pomace obtained during processing as a residue of tomato processing from large industry. The interactions between tomato pomace and fecal bacteria, bile acids during in vitro digestion were studied. Digestion was carried out by using bioreactor in...

Showing 1 to 12 of 222 entries