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Glucocorticoid replacement regimens for treating congenital adrenal hyperplasia.

The Cochrane database of systematic reviews

Ng SM, Stepien KM, Krishan A.
PMID: 32190901
Cochrane Database Syst Rev. 2020 Mar 19;3:CD012517. doi: 10.1002/14651858.CD012517.pub2.

BACKGROUND: Congenital adrenal hyperplasia (CAH) is an autosomal recessive condition which leads to glucocorticoid deficiency and is the most common cause of adrenal insufficiency in children. In over 90% of cases, 21-hydroxylase enzyme deficiency is found which is caused...

Testicular function in a birth cohort of young men.

Human reproduction (Oxford, England)

Hart RJ, Doherty DA, McLachlan RI, Walls ML, Keelan JA, Dickinson JE, Skakkebaek NE, Norman RJ, Handelsman DJ.
PMID: 26409015
Hum Reprod. 2015 Dec;30(12):2713-24. doi: 10.1093/humrep/dev244. Epub 2015 Sep 25.

STUDY QUESTION: By investigating a birth cohort with a high ongoing participation rate to derive an unbiased population, what are the parameters and influences upon testicular function for a population not selected with regard to fertility?SUMMARY ANSWER: While varicocele,...

Allostatic load, a measure of chronic physiological stress, is associated with pregnancy outcomes, but not fertility, among women with unexplained infertility.

Human reproduction (Oxford, England)

Barrett ES, Vitek W, Mbowe O, Thurston SW, Legro RS, Alvero R, Baker V, Bates GW, Casson P, Coutifaris C, Eisenberg E, Hansen K, Krawetz S, Robinson R, Rosen M, Usadi R, Zhang H, Santoro N, Diamond M.
PMID: 30085177
Hum Reprod. 2018 Sep 01;33(9):1757-1766. doi: 10.1093/humrep/dey261.

STUDY QUESTION: Among infertile women undergoing ovarian stimulation, is allostatic load (AL), a measure of chronic physiological stress, associated with subsequent fertility and pregnancy outcomes?SUMMARY ANSWER: AL at baseline was not associated with conception, spontaneous abortion or live birth,...

Gonadotrophin stimulation for in vitro fertilization significantly alters the hormone milieu in follicular fluid: a comparative study between natural cycle IVF and conventional IVF.

Human reproduction (Oxford, England)

von Wolff M, Kollmann Z, Flück CE, Stute P, Marti U, Weiss B, Bersinger NA.
PMID: 24608520
Hum Reprod. 2014 May;29(5):1049-57. doi: 10.1093/humrep/deu044. Epub 2014 Mar 06.

STUDY QUESTION: Is the steroid hormone profile in follicular fluid (FF) at the time of oocyte retrieval different in naturally matured follicles, as in natural cycle IVF (NC-IVF), compared with follicles stimulated with conventional gonadotrophin stimulated IVF (cIVF)?SUMMARY ANSWER:...

In vitro differentiation of theca cells from ovarian cells isolated from postmenopausal women.

Human reproduction (Oxford, England)

Asiabi P, Dolmans MM, Ambroise J, Camboni A, Amorim CA.
PMID: 33326997
Hum Reprod. 2020 Dec 01;35(12):2793-2807. doi: 10.1093/humrep/deaa246.

STUDY QUESTION: Can human theca cells (TCs) be differentiated in vitro?SUMMARY ANSWER: It is possible to differentiate human TCs in vitro using a medium supplemented with growth factors and hormones.WHAT IS KNOWN ALREADY: There are very few studies on...

Androgen levels in women with various forms of ovarian dysfunction: associations with cardiometabolic features.

Human reproduction (Oxford, England)

Daan NM, Jaspers L, Koster MP, Broekmans FJ, de Rijke YB, Franco OH, Laven JS, Kavousi M, Fauser BC.
PMID: 26269538
Hum Reprod. 2015 Oct;30(10):2376-86. doi: 10.1093/humrep/dev195. Epub 2015 Aug 12.

STUDY QUESTION: Are differences in androgen levels among women with various forms of ovarian dysfunction associated with cardiometabolic abnormalities?SUMMARY ANSWER: Androgen levels differed substantially between women with and without ovarian dysfunction, and increased androgen levels were associated with impaired...

Maternal smoking during pregnancy and reproductive health of daughters: a follow-up study spanning two decades.

Human reproduction (Oxford, England)

Ernst A, Kristensen SL, Toft G, Thulstrup AM, Håkonsen LB, Olsen SF, Ramlau-Hansen CH.
PMID: 23034153
Hum Reprod. 2012 Dec;27(12):3593-600. doi: 10.1093/humrep/des337. Epub 2012 Oct 02.

STUDY QUESTION: Does in utero exposure to constituents of cigarette smoke have a programming effect on daughters' age of menarche and markers of long-term reproductive health?SUMMARY ANSWER: In utero exposure to constituents of cigarette smoke was associated with earlier...

Relationship between the GH/IGF-I axis, insulin sensitivity, and adrenal androgens in normal prepubertal and pubertal boys.

The Journal of clinical endocrinology and metabolism

Guercio G, Rivarola MA, Chaler E, Maceiras M, Belgorosky A.
PMID: 11889181
J Clin Endocrinol Metab. 2002 Mar;87(3):1162-9. doi: 10.1210/jcem.87.3.8330.

In girls, but not in boys, pronounced adrenarche and precocious pubarche along with ovarian hyperandrogenism have been related to insulin resistance and reduced fetal growth. However, insulin secretion is increased during puberty in normal boys. The aim of this...

A comparison of the effects of oral contraceptives on the clinical and biochemical manifestations of polycystic ovary syndrome: a crossover randomized controlled trial.

Human reproduction (Oxford, England)

Amiri M, Nahidi F, Bidhendi-Yarandi R, Khalili D, Tohidi M, Ramezani Tehrani F.
PMID: 31916574
Hum Reprod. 2020 Jan 01;35(1):175-186. doi: 10.1093/humrep/dez255.

STUDY QUESTION: Do oral contraceptives (OCs) containing progestins with low androgenic or antiandrogenic activities have different effects to those containing levonorgestrel (LNG) on clinical, androgenic and metabolic manifestations of polycystic ovarian syndrome (PCOS)?SUMMARY ANSWER: The three OCs tested had...

EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium.

The Journal of steroid biochemistry and molecular biology

Labrie F, Labrie C, Bélanger A, Simard J, Gauthier S, Luu-The V, Mérand Y, Giguere V, Candas B, Luo S, Martel C, Singh SM, Fournier M, Coquet A, Richard V, Charbonneau R, Charpenet G, Tremblay A, Tremblay G, Cusan L, Veilleux R.
PMID: 10418981
J Steroid Biochem Mol Biol. 1999 Apr-Jun;69(1):51-84. doi: 10.1016/s0960-0760(99)00065-5.

Breast cancer is the most frequent cancer in women while it is the second cause of cancer death. Estrogens are well recognized to play the predominant role in breast cancer development and growth and much efforts have been devoted...

Maternal and fetal hypothalamic-pituitary-adrenal axes during pregnancy and postpartum.

Annals of the New York Academy of Sciences

Mastorakos G, Ilias I.
PMID: 14644820
Ann N Y Acad Sci. 2003 Nov;997:136-49. doi: 10.1196/annals.1290.016.

The principal modulators of the hypothalamic-pituitary-adrenal (HPA) axis are corticotropin-releasing hormone (CRH) and arginine-vasopressin (AVP). Corticotropin-releasing hormone is not exclusively produced in the hypothalamus. Its presence has been demonstrated at peripheral inflammatory sites. Ovulation and luteolysis bear characteristics of...

[Plasma metastin in adolescent polycystic ovary syndrome.].

Zhonghua fu chan ke za zhi

Chen XL, Mo YQ, Li L, Chen YX, Li Y, Zhang QX, Yang DZ.
PMID: 20078960
Zhonghua Fu Chan Ke Za Zhi. 2009 Oct;44(10):745-9.

OBJECTIVE: This study was designed to investigate the correlationship between plasma metastin and pathogenesis of adolescent women with polycystic ovary syndrome (PCOS).METHODS: From Jan. 2006 to Jun. 2006, 42 PCOS patients including 19 adolescent women and 23 adults with...

Showing 1 to 12 of 15883 entries