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Showing 1 to 12 of 342 entries
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Editorial: Modulating Prokaryotic Lifestyle by DNA-Binding Proteins: Learning from (Apparently) Simple Systems.

Frontiers in molecular biosciences

Venkova T, Juárez A, Espinosa M.
PMID: 28111626
Front Mol Biosci. 2017 Jan 06;3:86. doi: 10.3389/fmolb.2016.00086. eCollection 2016.

No abstract available.

Redox control of gene expression and the function of chloroplast genomes - an hypothesis.

Photosynthesis research

Allen JF.
PMID: 24318870
Photosynth Res. 1993 May;36(2):95-102. doi: 10.1007/BF00016274.

Two-component regulatory systems that respond to changes in redox potential have recently been discovered in bacteria. 'Redox sensors' are defined as electron carriers which initiate control of gene expression upon oxidation or reduction. 'Redox response regulators' are defined as...

Chloroplast RNA polymerase from spinach: purification and DNA-binding proteins.

Plant molecular biology

Lerbs S, Briat JF, Mache R.
PMID: 24318138
Plant Mol Biol. 1983 Mar;2(2):67-74. doi: 10.1007/BF01595167.

Spinach DNA dependent RNA polymerase was purified from isolated chloroplasts by two different procedures. Analysis of the protein composition of the two preparations by SDS-polyacrylamide gel electrophoresis always shows six abundant polypeptides with Mr of 150, 110, 102, 80,...

Computational methodology for ChIP-seq analysis.

Quantitative biology (Beijing, China)

Shin H, Liu T, Duan X, Zhang Y, Liu XS.
PMID: 25741452
Quant Biol. 2013 Mar 01;1(1):54-70. doi: 10.1007/s40484-013-0006-2.

Chromatin immunoprecipitation coupled with massive parallel sequencing (ChIP-seq) is a powerful technology to identify the genome-wide locations of DNA binding proteins such as transcription factors or modified histones. As more and more experimental laboratories are adopting ChIP-seq to unravel...

Environmental-stress-induced Chromatin Regulation and its Heritability.

Journal of carcinogenesis & mutagenesis

Fang L, Wuptra K, Chen D, Li H, Huang SK, Jin C, Yokoyama KK.
PMID: 25045581
J Carcinog Mutagen. 2014 Jan 15;5(1). doi: 10.4172/2157-2518.1000156.

Chromatin is subject to proofreading and repair mechanisms during the process of DNA replication, as well as repair to maintain genetic and epigenetic information and genome stability. The dynamic structure of chromatin modulates various nuclear processes, including transcription and...

Structure and Function of a Novel Silencer in 5' Flanking Distal Region of Human beta Globin Gene.

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica

Yang Y, Yang YY, Li HM, Zhu DE.
PMID: 12050787
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2001;33(3):286-290.

A novel silencer fragment(310 bp) was recently discovered and identified to locate between -2 132 bp and -1 822 bp upstream from the cap site of beta-globin gene by gel retardation assay and luciferase reporter gene expression analysis. DNA...

Design and Enantioselective Synthesis of a Peptidomimetic of the Turn in the Helix-Turn-Helix DNA-Binding Protein Motif.

The Journal of organic chemistry

Travins JM, Etzkorn FA.
PMID: 11671976
J Org Chem. 1997 Nov 28;62(24):8387-8393. doi: 10.1021/jo971077h.

A peptidomimetic of the turn in the helix-turn-helix (HTH) motif of DNA-binding proteins was designed and synthesized. Conformational constraint was achieved by an unusual linking of two amino acids with a side chain carbon-carbon bond. A phenyl ring provides...

Phosphorylation of the beta' Subunit of RNA Polymerase and Other Host Proteins upon phiCd1 Infection of Caulobacter crescentus.

Journal of virology

Hodgson D, Shapiro L, Amemiya K.
PMID: 16789252
J Virol. 1985 Jul;55(1):238-41. doi: 10.1128/JVI.55.1.238-241.1985.

A protein kinase activity is induced early after infection of Caulobacter crescentus by the DNA phage phiCd1. After phage infection at least 40 proteins are phosphorylated; these include DNA-binding proteins, a membrane-associated protein, and several ribosomal proteins. One of...

Preliminary investigation of sequence-independent DNA binding proteins in rat skeletal muscle sarcoplasmic reticulum and their function.

Science in China. Series C, Life sciences

Zhao W, Jiang Z, Ni J, Chen K, Liu N, Tang J, Jia H, Tang C.
PMID: 18726374
Sci China C Life Sci. 2000 Apr;43(2):209-16. doi: 10.1007/BF02879130.

To observe the binding of plasmid DNA to non-nuclear DNA binding proteins in sarcoplasmic reticulum (SR) and the effects of this binding on SR function, sarcoplasmic reticulum proteins in rat skeletal muscle were isolated by differential centrifuge and sucrose...

The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?.

Nuclear receptor signaling

Ramakrishnan SN, Muscat GE.
PMID: 16741567
Nucl Recept Signal. 2006;4:e009. doi: 10.1621/nrs.04009. Epub 2006 Apr 28.

Nuclear hormone receptors (NRs) function as ligand dependent DNA binding proteins that translate physiological/nutritional signals into gene regulation. Dysfunctional NR signaling leads to many disorders in reproduction, inflammation, and metabolism. The opportunity to identify novel regulatory pathways in the...

An improved strategy for constructing "designer" Cys2His2 zinc finger proteins.

Discovery medicine

Thibodeau SA, Joung JK.
PMID: 20705034
Discov Med. 2003 Dec;3(19):32-5.

Extract: The Cys2His2 zinc finger domain (hereafter simply "zinc finger") provides a useful scaffold for creating customized DNA-binding proteins, a technology with potential applications in biological research, molecular medicine, and gene therapy. Using a combination of targeted randomization and...

Subdiffusion and weak ergodicity breaking in the presence of a reactive boundary.

Physical review letters

Lomholt MA, Zaid IM, Metzler R.
PMID: 17677681
Phys Rev Lett. 2007 May 18;98(20):200603. doi: 10.1103/PhysRevLett.98.200603. Epub 2007 May 16.

We derive the boundary condition for a subdiffusive particle interacting with a reactive boundary with a finite reaction rate. Molecular crowding conditions, that are found to cause subdiffusion of larger molecules in biological cells, are shown to effect long-tailed...

Showing 1 to 12 of 342 entries