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Showing 1 to 12 of 13 entries
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Table: Safety of drugs for IBS in pregnancy and lactation (online only).

The Medical letter on drugs and therapeutics

[No authors listed]
PMID: 32324174
Med Lett Drugs Ther. 2020 Mar 23;62(1594):e48-e49.

No abstract available.

Imaging Atherosclerosis by Carotid Intima-media Thickness in vivo: How to, Where and in Whom ?.

Maedica

Onut R, Balanescu AP, Constantinescu D, Calmac L, Marinescu M, Dorobantu PM.
PMID: 23399970
Maedica (Bucur). 2012 Jun;7(2):153-62.

Carotid intima-media thickness (CIMT) can be reliably determined in vivo by carotidian ultrasound and is an accessible and reliable method to assess subclinical atherosclerosis. Available epidemiological data showed that CIMT is significantly correlated with future cardiovascular events. However it...

Management of Diarrhea in Patients with HER2-Positive Breast Cancer Treated with Neratinib: A Case Series and Summary of the Literature.

Oncology and therapy

Kruse ML, Kang IM, Bagegni NA, Howell WT, Moore HCF, Bedell CH, Stokoe CT.
PMID: 34800263
Oncol Ther. 2021 Nov 20; doi: 10.1007/s40487-021-00178-w. Epub 2021 Nov 20.

INTRODUCTION: Neratinib and neratinib-based combinations have demonstrated efficacy for treatment of human epidermal growth factor receptor 2-positive (HER2+) early-stage and metastatic breast cancers. However, diarrhea has been reported as a common adverse event leading to neratinib discontinuation. Results from...

Atorvastatin, a New HMG-CoA Reductase Inhibitor as Monotherapy and Combined With Colestipol.

Journal of cardiovascular pharmacology and therapeutics

Heinonen TM, Schrott H, McKenney JM, Sniderman AD, Broyles FE, Zavoral JH, Kivel F, Black DM.
PMID: 10684408
J Cardiovasc Pharmacol Ther. 1996 Apr;1(2):117-122. doi: 10.1177/107424849600100205.

BACKGROUND: Atorvastatin, a new HMG-CoA reductase inhibitor in clinical development has demonstrated an acceptable safety profile and marked cholesterol and triglyceride reduction at doses ranging from 10-80 mg/day. Since bile acid sequestering resins are often used in combination with...

Chronic Diarrhea.

Current treatment options in gastroenterology

Schiller LR.
PMID: 15913515
Curr Treat Options Gastroenterol. 2005 Jun;8(3):259-266. doi: 10.1007/s11938-005-0018-8.

Chronic diarrhea can be due to any of several hundred conditions. When investigation fails to uncover a specific cause that can be treated successfully, nonspecific therapy is implemented. This includes dietary alterations if specific aggravating foods can be identified,...

Managing bile acid diarrhoea.

Therapeutic advances in gastroenterology

Walters JR, Pattni SS.
PMID: 21180614
Therap Adv Gastroenterol. 2010 Nov;3(6):349-57. doi: 10.1177/1756283X10377126.

Bowel symptoms including diarrhoea can be produced when excess bile acids (BA) are present in the colon. This condition, known as bile acid or bile salt malabsorption, has been under recognized, as the best diagnostic method, the (75)Se-homocholic acid...

Dose--Response Study of Colestipol Tablets in Patients with Moderate Hypercholesterolemia.

American journal of therapeutics

Hunninghake DB, Stein EA, Bremner WF, Greenland P, Demke DM, Oliphant TH.
PMID: 11847550
Am J Ther. 1995 Mar;2(3):180-189. doi: 10.1097/00045391-199503000-00006.

The purpose of the study was to evaluate the efficacy and safety of a new formulation of colestipol provided in table form. This was a randomized, double-blind, placebo-controlled, multicenter, dose-ranging study. A total of 196 patients with primary hypercholesterolemia...

Treatment of Biliary Problems in Inflammatory Bowel Disease.

Current treatment options in gastroenterology

Huang CS, Lichtenstein DR.
PMID: 15769433
Curr Treat Options Gastroenterol. 2005 Apr;8(2):117-126. doi: 10.1007/s11938-005-0004-1.

The most common biliary problem in patients with inflammatory bowel disease is primary sclerosing cholangitis (PSC). The treatment of this disease is multifaceted and frequently requires a multidisciplinary approach involving internists, nutritionists, gastroenterologists, and surgeons. Unfortunately, other than liver...

A US military perspective.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Remund DD, Sutton EL.
PMID: 16674545
Value Health. 1998 Nov;1(4):228-30. doi: 10.1046/j.1524-4733.1998.140228.x.

This paper discusses lipid therapy decision-making at the population level within the United States (US) Military Health Services System. The US Military Health Services System serves approximately 8.2 million beneficiaries fairly representative of the general population. Of its $680...

Effect of bile acid sequestrants on glycaemic control: protocol for a systematic review with meta-analysis of randomised controlled trials.

BMJ open

Hansen M, Sonne DP, Mikkelsen KH, Gluud LL, Vilsbøll T, Knop FK.
PMID: 23148345
BMJ Open. 2012 Nov 12;2(6). doi: 10.1136/bmjopen-2012-001803. Print 2012.

INTRODUCTION: In addition to the lipid-lowering effect of bile acid sequestrants (BASs), they also lower blood glucose and, therefore, could be beneficial in the treatment of patients with type 2 diabetes mellitus (T2DM). Three oral BASs are approved by...

Atorvastatin, a New HMG-CoA Reductase Inhibitor, Does Not Affect Glucocorticoid Hormones in Patients With Hypercholesterolemia.

Journal of cardiovascular pharmacology and therapeutics

Isaacsohn JL, Bakker-Arkema RG, Fayyad R, Whitcomb R, Black DM.
PMID: 10684465
J Cardiovasc Pharmacol Ther. 1997 Oct;2(4):243-249. doi: 10.1177/107424849700200402.

BACKGROUND: Atorvastatin calcium (Lipitor) is a new 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. The present study was conducted to examine the effect of pronounced cholesterol lowering on adrenal function in patients with severe hypercholesterolemia. METHODS AND RESULTS: Adrenal function was...

Lymphocytic and Collagenous Colitis: Medical Management.

Current treatment options in gastroenterology

Marshall JK, Irvine EJ.
PMID: 11096583
Curr Treat Options Gastroenterol. 1999 Apr;2(2):127-133. doi: 10.1007/s11938-999-0040-3.

When possible, patients taking nonsteroidal anti-inflammatory medications should discontinue them when the diagnosis of microscopic colitis is made. Although there is no direct evidence of its efficacy, a trial of elimination of caffeine or lactose or both should be...

Showing 1 to 12 of 13 entries