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Showing 1 to 12 of 1369 entries
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Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.

Nature communications

Weinert T, Olieric N, Cheng R, Brünle S, James D, Ozerov D, Gashi D, Vera L, Marsh M, Jaeger K, Dworkowski F, Panepucci E, Basu S, Skopintsev P, Doré AS, Geng T, Cooke RM, Liang M, Prota AE, Panneels V, Nogly P, Ermler U, Schertler G, Hennig M, Steinmetz MO, Wang M, Standfuss J.
PMID: 28912485
Nat Commun. 2017 Sep 14;8(1):542. doi: 10.1038/s41467-017-00630-4.

Historically, room-temperature structure determination was succeeded by cryo-crystallography to mitigate radiation damage. Here, we demonstrate that serial millisecond crystallography at a synchrotron beamline equipped with high-viscosity injector and high frame-rate detector allows typical crystallographic experiments to be performed at...

Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants.

Cell transplantation

Willis L, Quintero EM, Nelson M, Granholm AC.
PMID: 28863735
Cell Transplant. 2005 Jan;14(1):21-29. doi: 10.3727/000000005783983313.

Trophic factors have been found to play a significant role both in long-term survival processes and in more rapid and dynamic processes in the brain and spinal cord. However, little is known regarding the regulation of expression of growth...

Poster 97 Statin-Induced Rhabdomyolysis Triggered by Concomitant Colchicine Administration: A Case Report.

PM & R : the journal of injury, function, and rehabilitation

Auriemma MJ, Bunning RD.
PMID: 27672864
PM R. 2016 Sep;8(9):S193. doi: 10.1016/j.pmrj.2016.07.140. Epub 2016 Sep 24.

No abstract available.

Familial Mediterranean Fever With Complete Symptomatic Remission During Pregnancy.

Intestinal research

Kim KT, Jang HJ, Lee JE, Kim MK, Yoo JJ, Lee GY, Kae SH, Lee J.
PMID: 26131005
Intest Res. 2015 Jul;13(3):287-90. doi: 10.5217/ir.2015.13.3.287. Epub 2015 Jun 09.

Familial Mediterranean fever (FMF) is an inherited autosomal recessive disorder, ethnically restricted and commonly found among populations surrounding the Mediterranean Sea. FMF is the most prevalent autoinflammatory disease; is characterized by recurrent, self-limited episodes of fever with serositis; and...

Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA) Syndrome in Iranian Children First Report of Iranian Periodic Fever and Autoinflammatory Registry (IPFAIR).

Iranian journal of pediatrics

Mehregan FF, Ziaee V, Ahmadinejad Z, Tahghighi F, Sabouni F, Moradinejad MH.
PMID: 25793068
Iran J Pediatr. 2014 Oct;24(5):598-602. Epub 2014 Oct 24.

OBJECTIVE: The periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome is a nonhereditary idiopathic febrile syndrome belonging to the group of autoinflammatory diseases. No longtime sequel was reported in this disease. Early diagnosis can lead physicians to...

Bone Mineral Density in Egyptian Children with Familial Mediterranean Fever.

Iranian journal of medical sciences

Salah S, El-Masry SA, Sheba HF, El-Banna RA, Saad W.
PMID: 26722138
Iran J Med Sci. 2016 Jan;41(1):2-8.

BACKGROUND: Familial Mediterranean fever (FMF) has episodic or subclinical inflammation that may lead to a decrease in bone mineral density (BMD). The objective of this study was to assess BMD in Egyptian children with FMF on genetic basis.METHODS: A...

Synthesis and Structure-Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents.

ACS medicinal chemistry letters

Kuroiwa K, Ishii H, Matsuno K, Asai A, Suzuki Y.
PMID: 25815147
ACS Med Chem Lett. 2015 Jan 10;6(3):287-91. doi: 10.1021/ml5004684. eCollection 2015 Mar 12.

A quinazoline derivative PVHD121 (1a) was shown to have strong antiproliferative activity against various tumor-derived cell lines, including A549 (lung), NCI-H460 (lung), HCT116 (colon), MCF7 (breast), PC3 (prostate), and HeLa (cervical) cells with IC50 values from 0.1 to 0.3...

Behcet's Disease (A Study of 23 Cases From Tripoli, Libya).

Indian journal of dermatology, venereology and leprology

Khatri ML, Shafi M.
PMID: 28145372
Indian J Dermatol Venereol Leprol. 1987 Sep-Oct;53(5):282-285.

In a study of 23 cases of Behcet's disease, we found male prepondrance (males 82.6%, females 17.4%) with commonest age of onset between 21-30 years in 70% cases. During the course of the disease, recurrent oro- genital ulcers were...

Periodic Fever and Neutrophilic Dermatosis: Is It Sweet's Syndrome?.

Case reports in immunology

Assari R, Ziaee V, Parvaneh N, Moradinejad MH.
PMID: 25544911
Case Reports Immunol. 2014;2014:320920. doi: 10.1155/2014/320920. Epub 2014 Dec 04.

A 7-year-old boy with high grade fever (39°C) and warm, erythematous, and indurated plaque above the left knee was referred. According to the previous records of this patient, these indurated plaques had been changed toward abscesses formation and then...

Orientation of cellulose microfibrils in cortical cells of tobacco explants : Effects of microtubule-depolymerizing drugs.

Planta

Wilms FH, Wolters-Arts AM, Derksen J.
PMID: 24196992
Planta. 1990 Aug;182(1):1-8. doi: 10.1007/BF00239976.

The deposition of nascent cellulose microfibrils (CMFs) was studied in the walls of cortical cells in explants of Nicotiana tabacum L. flower stalks. In freshly cut explants the CMFs were deposited in two distinct and alternating orientations - all...

A comparison of the effects of various spindle toxins on metaphase arrest and formation of micronuclei in cell-suspension cultures ofNicotiana plumbaginifolia.

Planta

Verhoeven HA, Sree Ramulu K, Dijkhuis P.
PMID: 24197192
Planta. 1990 Oct;182(3):408-14. doi: 10.1007/BF02411392.

The effects of the spindle toxins colchicine, oryzalin and amiprophos-methyl (APM) on metaphase arrest, chromosome scattering, and on the induction and yield of micronuclei were compared in suspension cells ofNicotiana plumbaginifolia (kanamycin-resistant "Doba" line). The inhibition of spindle formation...

Theoretical Study of the Photochemical Isomerization of Colchicine.

Journal of chemical theory and computation

Cacelli I, D'Auria M, Villani V.
PMID: 26637043
J Chem Theory Comput. 2007 Mar;3(2):649-56. doi: 10.1021/ct600306t.

The photochemical reaction of colchicine to β- and γ-lumicolchicine, through a mechanism involving a disrotatory cyclization, is studied by theoretical methods. The energetics of the reaction, including one or two methanol solvent molecules, are studied at the DFT-B3LYP and...

Showing 1 to 12 of 1369 entries