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Showing 1 to 12 of 369 entries
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Surface plasmon resonance as detection tool for lipids lateral mobility in biomimetic membranes.

Biomedical optics express

Margheri G, D'Agostino R, Becucci L, Guidelli R, Tiribilli B, Del Rosso M.
PMID: 23243563
Biomed Opt Express. 2012 Dec 01;3(12):3119-26. doi: 10.1364/BOE.3.003119. Epub 2012 Nov 06.

A procedure based on surface plasmon resonance (SPR) is proposed to monitor the lateral mobility of lipid molecules in solid-supported bilayer lipid membranes (ssBLMs), an essential prerequisite for the formation of important microdomains called lipid rafts (LRs). The procedure...

The role of Peyer's patches in synchronizing gut IgA responses.

Frontiers in immunology

Lycke NY, Bemark M.
PMID: 23181060
Front Immunol. 2012 Nov 07;3:329. doi: 10.3389/fimmu.2012.00329. eCollection 2012.

Because Peyer's patches (PP) are the main inductive sites for gut IgA responses we have focused this review on what we know about the function of PP germinal centers (GC). The vast majority of IgA gene sequences in the...

Antibody Production, Anaphylactic Signs, and T-Cell Responses Induced by Oral Sensitization With Ovalbumin in BALB/c and C3H/HeOuJ Mice.

Allergy, asthma & immunology research

Pablos-Tanarro A, López-Expósito I, Lozano-Ojalvo D, López-Fandiño R, Molina E.
PMID: 26922934
Allergy Asthma Immunol Res. 2016 May;8(3):239-45. doi: 10.4168/aair.2016.8.3.239.

PURPOSE: Two mouse strains, BALB/c and C3H/HeOuJ, broadly used in the field of food allergy, were compared for the evaluation of the allergenic potential of ovalbumin (OVA).METHODS: Sensitization was made by administering 2 different OVA doses (1 and 5...

Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin.

Frontiers in immunology

Sun JB, Holmgren J, Larena M, Terrinoni M, Fang Y, Bresnick AR, Xiang Z.
PMID: 28951732
Front Immunol. 2017 Sep 11;8:1119. doi: 10.3389/fimmu.2017.01119. eCollection 2017.

The calcium-binding protein S100A4 has been described to promote pathological inflammation in experimental autoimmune and inflammatory disorders and in allergy and to contribute to antigen presentation and antibody response after parenteral immunization with an alum-adjuvanted antigen. In this study,...

N-Glycosylation of Cholera Toxin B Subunit: Serendipity for Novel Plant-Made Vaccines?.

Frontiers in plant science

Matoba N.
PMID: 26732492
Front Plant Sci. 2015 Dec 22;6:1132. doi: 10.3389/fpls.2015.01132. eCollection 2015.

The non-toxic B subunit of cholera toxin (CTB) has attracted considerable interests from vaccinologists due to strong mucosal immunomodulatory effects and potential utility as a vaccine scaffold for heterologous antigens. Along with other conventional protein expression systems, various plant...

Connections of the juxtaventromedial region of the lateral hypothalamic area in the male rat.

Frontiers in systems neuroscience

Hahn JD, Swanson LW.
PMID: 26074786
Front Syst Neurosci. 2015 May 27;9:66. doi: 10.3389/fnsys.2015.00066. eCollection 2015.

UNLABELLED: Evolutionary conservation of the hypothalamus attests to its critical role in the control of fundamental behaviors. However, our knowledge of hypothalamic connections is incomplete, particularly for the lateral hypothalamic area (LHA). Here we present the results of neuronal...

Detection of cholera (ctx) and zonula occludens (zot) toxin genes in Vibrio cholerae O1, O139 and non-O1 strains.

World journal of microbiology & biotechnology

Rivera IG, Chowdhury MA, Sanchez PS, Sato MI, Huq A, Colwell RR, Martins MT.
PMID: 24414916
World J Microbiol Biotechnol. 1995 Sep;11(5):572-7. doi: 10.1007/BF00286376.

Vibrio cholerae O1 and V. cholerae non-O1 strains isolated from environmental samples collected in São Paulo, Brazil, during cholera epidemics and pre-epidemic periods were examined for the presence of toxin genes. V. cholerae O1 strains isolated from clinical samples...

Detecting Protein-Glycolipid Interactions Using Glycomicelles and CaR-ESI-MS.

Journal of the American Society for Mass Spectrometry

Han L, Kitova EN, Klassen JS.
PMID: 27549393
J Am Soc Mass Spectrom. 2016 Nov;27(11):1878-1886. doi: 10.1007/s13361-016-1461-6. Epub 2016 Aug 22.

This study reports on the use of the catch-and-release electrospray ionization mass spectrometry (CaR-ESI-MS) assay, combined with glycomicelles, as a method for detecting specific interactions between water-soluble proteins and glycolipids (GLs) in aqueous solution. The B subunit homopentamers of...

High-throughput imaging method for direct assessment of GM1 ganglioside levels in mammalian cells.

Data in brief

Acosta W, Martin R, Radin DN, Cramer CL.
PMID: 26958633
Data Brief. 2016 Feb 03;6:1016-22. doi: 10.1016/j.dib.2016.01.027. eCollection 2016 Mar.

GM1-gangliosidosis is an inherited autosomal recessive disorder caused by mutations in the gene GLB1, which encodes acid β-galactosidase (β-gal). The lack of activity in this lysosomal enzyme leads to accumulation of GM1 gangliosides (GM1) in cells. We have developed...

Curcumin utilizes the anti-inflammatory response pathway to protect the intestine against bacterial invasion.

Nutrition research and practice

Cho JA, Park E.
PMID: 25861416
Nutr Res Pract. 2015 Apr;9(2):117-22. doi: 10.4162/nrp.2015.9.2.117. Epub 2015 Mar 06.

BACKGROUND/OBJECTIVES: Curcumin, a major component of the Curcuma species, contains antioxidant and anti-inflammatory properties. Although it was found to induce apoptosis in cancer cells, the functional role of curcumin as well as its molecular mechanism in anti-inflammatory response, particularly...

Oral Immunization Against Candidiasis Using Lactobacillus casei Displaying Enolase 1 from Candida albicans.

Scientia pharmaceutica

Shibasaki S, Karasaki M, Tafuku S, Aoki W, Sewaki T, Ueda M.
PMID: 25853077
Sci Pharm. 2014 Jul 23;82(3):697-708. doi: 10.3797/scipharm.1404-07. Print 2014.

Candidiasis is a common fungal infection that is prevalent in immunocompromised individuals. In this study, an oral vaccine against Candida albicans was developed by using the molecular display approach. Enolase 1 protein (Eno1p) of C. albicans was expressed on...

Endothelin-evoked Release of Arachidonic Acid from Mouse Astrocytes in Primary Culture.

The European journal of neuroscience

Tencé M, Cordier J, Glowinski J, Prémont J.
PMID: 12106434
Eur J Neurosci. 1992;4(10):993-999. doi: 10.1111/j.1460-9568.1992.tb00125.x.

In striatal astrocytes, receptors for the vasoactive peptide endothelin (ET) are associated with several intracellular signalling pathways: ET-1 increases the breakdown of phosphoinositides, induces a sustained influx of Ca2+ and inhibits the isoproterenol-induced formation of cAMP (Marin et al.,...

Showing 1 to 12 of 369 entries