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Showing 1 to 12 of 12 entries
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Nausea and Vomiting.

Current treatment options in gastroenterology

Fraga XF, Malagelada JR.
PMID: 12095471
Curr Treat Options Gastroenterol. 2002 Aug;5(4):241-250. doi: 10.1007/s11938-002-0046-6.

Nausea and vomiting are rather stereotyped symptoms. The challenge is that nausea and vomiting have many different causes and, in some patients, management may be rather complex. The clue is to determine the causal factor early. It helps to...

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Fraga XF, Malagelada JR. Nausea and Vomiting. Curr Treat Options Gastroenterol. 2002;5(4):241-250doi: 10.1007/s11938-002-0046-6.
Fraga, X. F., & Malagelada, J. R. (2002). Nausea and Vomiting. Current treatment options in gastroenterology, 5(4), 241-250. https://doi.org/10.1007/s11938-002-0046-6
Fraga, Xose Fernández, and Malagelada, Juan R.. "Nausea and Vomiting." Current treatment options in gastroenterology vol. 5,4 (2002): 241-250. doi: https://doi.org/10.1007/s11938-002-0046-6
Fraga XF, Malagelada JR. Nausea and Vomiting. Curr Treat Options Gastroenterol. 2002 Aug;5(4):241-250. doi: 10.1007/s11938-002-0046-6. PMID: 12095471.
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Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles.

Biological & pharmaceutical bulletin

Obara K, Matsuoka Y, Iwata N, Abe Y, Ikegami Y, Shioda N, Hattori Y, Hamamatsu S, Yoshioka K, Yamaki F, Matsuo K, Yoshio T, Tanaka Y.
PMID: 34334499
Biol Pharm Bull. 2021;44(8):1140-1150. doi: 10.1248/bpb.b21-00363.

The clinical applications of antipsychotics for symptoms unrelated to schizophrenia, such as behavioral and psychological symptoms, in patients with Alzheimer's disease, and the likelihood of doctors prescribing antipsychotics for elderly people are increasing. In elderly people, drug-induced and aging-associated...

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Obara K, Matsuoka Y, Iwata N, et al. Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles. Biol Pharm Bull. 2021;44(8):1140-1150doi: 10.1248/bpb.b21-00363.
Obara, K., Matsuoka, Y., Iwata, N., Abe, Y., Ikegami, Y., Shioda, N., Hattori, Y., Hamamatsu, S., Yoshioka, K., Yamaki, F., Matsuo, K., Yoshio, T., & Tanaka, Y. (2021). Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles. Biological & pharmaceutical bulletin, 44(8), 1140-1150. https://doi.org/10.1248/bpb.b21-00363
Obara, Keisuke, et al. "Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles." Biological & pharmaceutical bulletin vol. 44,8 (2021): 1140-1150. doi: https://doi.org/10.1248/bpb.b21-00363
Obara K, Matsuoka Y, Iwata N, Abe Y, Ikegami Y, Shioda N, Hattori Y, Hamamatsu S, Yoshioka K, Yamaki F, Matsuo K, Yoshio T, Tanaka Y. Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles. Biol Pharm Bull. 2021;44(8):1140-1150. doi: 10.1248/bpb.b21-00363. PMID: 34334499.
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Intramolecular H-atom abstraction in gamma-azido-butyrophenones: formation of 1,5 ketyl iminyl radicals.

Organic letters

Muthukrishnan S, Sankaranarayanan J, Klima RF, Pace TC, Bohne C, Gudmundsdottir AD.
PMID: 19432450
Org Lett. 2009 Jun 04;11(11):2345-8. doi: 10.1021/ol900754a.

Photolysis of gamma-azidobutyrophenone derivatives yields 1,4 ketyl biradicals via intramolecular H-atom abstraction. The 1,4 ketyl biradicals expel a nitrogen molecule to form 1,5 ketyl iminyl biradicals, which decay by ring closure to form a new carbon-nitrogen bond. The 1,5...

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Muthukrishnan S, Sankaranarayanan J, Klima RF, et al. Intramolecular H-atom abstraction in gamma-azido-butyrophenones: formation of 1,5 ketyl iminyl radicals. Org Lett. 2009;11(11):2345-8doi: 10.1021/ol900754a.
Muthukrishnan, S., Sankaranarayanan, J., Klima, R. F., Pace, T. C., Bohne, C., & Gudmundsdottir, A. D. (2009). Intramolecular H-atom abstraction in gamma-azido-butyrophenones: formation of 1,5 ketyl iminyl radicals. Organic letters, 11(11), 2345-8. https://doi.org/10.1021/ol900754a
Muthukrishnan, Sivaramakrishnan, et al. "Intramolecular H-atom abstraction in gamma-azido-butyrophenones: formation of 1,5 ketyl iminyl radicals." Organic letters vol. 11,11 (2009): 2345-8. doi: https://doi.org/10.1021/ol900754a
Muthukrishnan S, Sankaranarayanan J, Klima RF, Pace TC, Bohne C, Gudmundsdottir AD. Intramolecular H-atom abstraction in gamma-azido-butyrophenones: formation of 1,5 ketyl iminyl radicals. Org Lett. 2009 Jun 04;11(11):2345-8. doi: 10.1021/ol900754a. PMID: 19432450.
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Postoperative nausea and vomiting: A simple yet complex problem.

Anesthesia, essays and researches

Shaikh SI, Nagarekha D, Hegade G, Marutheesh M.
PMID: 27746521
Anesth Essays Res. 2016 Sep-Dec;10(3):388-396. doi: 10.4103/0259-1162.179310.

Postoperative nausea and vomiting (PONV) is one of the complex and significant problems in anesthesia practice, with growing trend toward ambulatory and day care surgeries. This review focuses on pathophysiology, pharmacological prophylaxis, and rescue therapy for PONV. We searched...

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Shaikh SI, Nagarekha D, Hegade G, et al. Postoperative nausea and vomiting: A simple yet complex problem. Anesth Essays Res. 2016;10(3):388-396doi: 10.4103/0259-1162.179310.
Shaikh, S. I., Nagarekha, D., Hegade, G., & Marutheesh, M. (2016). Postoperative nausea and vomiting: A simple yet complex problem. Anesthesia, essays and researches, 10(3), 388-396. https://doi.org/10.4103/0259-1162.179310
Shaikh, Safiya Imtiaz, et al. "Postoperative nausea and vomiting: A simple yet complex problem." Anesthesia, essays and researches vol. 10,3 (2016): 388-396. doi: https://doi.org/10.4103/0259-1162.179310
Shaikh SI, Nagarekha D, Hegade G, Marutheesh M. Postoperative nausea and vomiting: A simple yet complex problem. Anesth Essays Res. 2016 Sep-Dec;10(3):388-396. doi: 10.4103/0259-1162.179310. PMID: 27746521; PMCID: PMC5062207.
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Palonosetron and granisetron in postoperative nausea vomiting: A randomized double-blind prospective study.

Anesthesia, essays and researches

Gugale AA, Bhalerao PM.
PMID: 27746523
Anesth Essays Res. 2016 Sep-Dec;10(3):402-407. doi: 10.4103/0259-1162.191121.

BACKGROUND: Postoperative nausea and vomiting (PONV) is a common occurrence after laparoscopic surgeries. A number of pharmacological agents (antihistamines, butyrophenones, dopamine receptor antagonists) have been tried of which the 5-hydroxytryptamine type 3 receptor antagonists are devoid of most side...

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Gugale AA, Bhalerao PM. Palonosetron and granisetron in postoperative nausea vomiting: A randomized double-blind prospective study. Anesth Essays Res. 2016;10(3):402-407doi: 10.4103/0259-1162.191121.
Gugale, A. A., & Bhalerao, P. M. (2016). Palonosetron and granisetron in postoperative nausea vomiting: A randomized double-blind prospective study. Anesthesia, essays and researches, 10(3), 402-407. https://doi.org/10.4103/0259-1162.191121
Gugale, Amrita A, and Bhalerao, Pradnya Milind. "Palonosetron and granisetron in postoperative nausea vomiting: A randomized double-blind prospective study." Anesthesia, essays and researches vol. 10,3 (2016): 402-407. doi: https://doi.org/10.4103/0259-1162.191121
Gugale AA, Bhalerao PM. Palonosetron and granisetron in postoperative nausea vomiting: A randomized double-blind prospective study. Anesth Essays Res. 2016 Sep-Dec;10(3):402-407. doi: 10.4103/0259-1162.191121. PMID: 27746523; PMCID: PMC5062237.
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Overdose profiles of new antipsychotic agents.

The international journal of neuropsychopharmacology

Capel MM, Colbridge MG, Henry JA.
PMID: 11343578
Int J Neuropsychopharmacol. 2000 Mar;3(1):51-54. doi: 10.1017/S1461145700001760.

Although the more recently introduced antipsychotic drugs are increasing in popularity, the pattern of symptomatology when taken in overdose is not well defined. We monitored all enquiries to the National Poisons Information Service, London (NPIS, London) concerning antipsychotic drugs...

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Capel MM, Colbridge MG, Henry JA. Overdose profiles of new antipsychotic agents. Int J Neuropsychopharmacol. 2000;3(1):51-54doi: 10.1017/S1461145700001760.
Capel, M. M., Colbridge, M. G., & Henry, J. A. (2000). Overdose profiles of new antipsychotic agents. The international journal of neuropsychopharmacology, 3(1), 51-54. https://doi.org/10.1017/S1461145700001760
Capel, Margred M., et al. "Overdose profiles of new antipsychotic agents." The international journal of neuropsychopharmacology vol. 3,1 (2000): 51-54. doi: https://doi.org/10.1017/S1461145700001760
Capel MM, Colbridge MG, Henry JA. Overdose profiles of new antipsychotic agents. Int J Neuropsychopharmacol. 2000 Mar;3(1):51-54. doi: 10.1017/S1461145700001760. PMID: 11343578.
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Spectrophotometric study of the charge transfer complexes of some pharmaceutical butyrophenones.

Talanta

Askal HF.
PMID: 18966914
Talanta. 1997 Oct;44(10):1749-55. doi: 10.1016/S0039-9140(97)00043-X.

The molecular interactions between haloperidol and droperidol as electron donors and each of iodine; 7,7,8,8-tetracyanoquinodimethane (TCNQ); 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ); tetracyanoethylene (TCNE); 2,4,7-trinitro-9-fluorenon (TNF); and 2-3-5-6-tetrabromo-1,4-benzoquinone (Bromanil) as acceptors have been investigated spectrophotometrically. Different variables affecting the reaction were studies and...

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Askal HF. Spectrophotometric study of the charge transfer complexes of some pharmaceutical butyrophenones. Talanta. 1997;44(10):1749-55doi: 10.1016/S0039-9140(97)00043-X.
Askal, H. F. (1997). Spectrophotometric study of the charge transfer complexes of some pharmaceutical butyrophenones. Talanta, 44(10), 1749-55. https://doi.org/10.1016/S0039-9140(97)00043-X
Askal, H F. "Spectrophotometric study of the charge transfer complexes of some pharmaceutical butyrophenones." Talanta vol. 44,10 (1997): 1749-55. doi: https://doi.org/10.1016/S0039-9140(97)00043-X
Askal HF. Spectrophotometric study of the charge transfer complexes of some pharmaceutical butyrophenones. Talanta. 1997 Oct;44(10):1749-55. doi: 10.1016/S0039-9140(97)00043-X. PMID: 18966914.
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Monoclonal antibodies directed against the drug haloperidol.

Neurochemistry international

Juszczak R, Strange PG.
PMID: 20501186
Neurochem Int. 1987;11(4):389-95. doi: 10.1016/0197-0186(87)90028-3.

Haloperidol coupled to albumin via the hydroxyl or carbonyl group has been used to obtain two classes of monoclonal anti-haloperidol antibodies. Both classes of monoclonal antibody bind haloperidol with high affinity but whereas one class is highly specific for...

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Juszczak R, Strange PG. Monoclonal antibodies directed against the drug haloperidol. Neurochem Int. 1987;11(4):389-95doi: 10.1016/0197-0186(87)90028-3.
Juszczak, R., & Strange, P. G. (1987). Monoclonal antibodies directed against the drug haloperidol. Neurochemistry international, 11(4), 389-95. https://doi.org/10.1016/0197-0186(87)90028-3
Juszczak, R, and Strange, P G. "Monoclonal antibodies directed against the drug haloperidol." Neurochemistry international vol. 11,4 (1987): 389-95. doi: https://doi.org/10.1016/0197-0186(87)90028-3
Juszczak R, Strange PG. Monoclonal antibodies directed against the drug haloperidol. Neurochem Int. 1987;11(4):389-95. doi: 10.1016/0197-0186(87)90028-3. PMID: 20501186.
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Olanzapine: an antiemetic option for chemotherapy-induced nausea and vomiting.

Journal of the advanced practitioner in oncology

Brafford MV, Glode A.
PMID: 25032030
J Adv Pract Oncol. 2014 Jan;5(1):24-9. doi: 10.6004/jadpro.2014.5.1.8.

Despite the appropriate use of pharmacologic and nonpharmacologic preventative measures, chemotherapy-induced nausea and vomiting (CINV) can be debilitating and can decrease quality of life for many patients. In addition, patients may be unwilling to continue chemotherapy treatment due to...

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Brafford MV, Glode A. Olanzapine: an antiemetic option for chemotherapy-induced nausea and vomiting. J Adv Pract Oncol. 2014;5(1):24-9doi: 10.6004/jadpro.2014.5.1.8.
Brafford, M. V., & Glode, A. (2014). Olanzapine: an antiemetic option for chemotherapy-induced nausea and vomiting. Journal of the advanced practitioner in oncology, 5(1), 24-9. https://doi.org/10.6004/jadpro.2014.5.1.8
Brafford, Megan V, and Glode, Ashley. "Olanzapine: an antiemetic option for chemotherapy-induced nausea and vomiting." Journal of the advanced practitioner in oncology vol. 5,1 (2014): 24-9. doi: https://doi.org/10.6004/jadpro.2014.5.1.8
Brafford MV, Glode A. Olanzapine: an antiemetic option for chemotherapy-induced nausea and vomiting. J Adv Pract Oncol. 2014 Jan;5(1):24-9. doi: 10.6004/jadpro.2014.5.1.8. PMID: 25032030; PMCID: PMC4093458.
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Dopamine receptor antagonists.

Annals of palliative medicine

Smith HS, Cox LR, Smith BR.
PMID: 25841474
Ann Palliat Med. 2012 Jul;1(2):137-42. doi: 10.3978/j.issn.2224-5820.2012.07.09.

Intractable nausea and/or vomiting is a serious and significant clinical dilemma that may greatly detract from quality of life. One of the first classes of antiemetic agents used as well as one of the commonest classes of antiemetic agents...

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Smith HS, Cox LR, Smith BR. Dopamine receptor antagonists. Ann Palliat Med. 2012;1(2):137-42doi: 10.3978/j.issn.2224-5820.2012.07.09.
Smith, H. S., Cox, L. R., & Smith, B. R. (2012). Dopamine receptor antagonists. Annals of palliative medicine, 1(2), 137-42. https://doi.org/10.3978/j.issn.2224-5820.2012.07.09
Smith, Howard S, et al. "Dopamine receptor antagonists." Annals of palliative medicine vol. 1,2 (2012): 137-42. doi: https://doi.org/10.3978/j.issn.2224-5820.2012.07.09
Smith HS, Cox LR, Smith BR. Dopamine receptor antagonists. Ann Palliat Med. 2012 Jul;1(2):137-42. doi: 10.3978/j.issn.2224-5820.2012.07.09. PMID: 25841474.
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Alpha-carbonyl substituent effect on the lifetimes of triplet 1,4-biradicals from Norrish-Type-II reactions.

Chemistry (Weinheim an der Bergstrasse, Germany)

Cai X, Cygon P, Goldfuss B, Griesbeck AG, Heckroth H, Fujitsuka M, Majima T.
PMID: 16557627
Chemistry. 2006 Jun 02;12(17):4662-7. doi: 10.1002/chem.200600011.

Triplet 1,4-biradicals were generated by Norrish-Type-II hydrogen transfer from alpha-heteroatom-substituted beta-branched butyrophenones 1-6 and detected by laser flash absorption measurements. For three oxy-substituted compounds 2-4 (R(alpha)=OH, OCOMe, OCOOEt) comparable lifetimes were determined in acetonitrile (roughly 1.5 micros). In benzene,...

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Cai X, Cygon P, Goldfuss B, et al. Alpha-carbonyl substituent effect on the lifetimes of triplet 1,4-biradicals from Norrish-Type-II reactions. Chemistry. 2006;12(17):4662-7doi: 10.1002/chem.200600011.
Cai, X., Cygon, P., Goldfuss, B., Griesbeck, A. G., Heckroth, H., Fujitsuka, M., & Majima, T. (2006). Alpha-carbonyl substituent effect on the lifetimes of triplet 1,4-biradicals from Norrish-Type-II reactions. Chemistry (Weinheim an der Bergstrasse, Germany), 12(17), 4662-7. https://doi.org/10.1002/chem.200600011
Cai, Xichen, et al. "Alpha-carbonyl substituent effect on the lifetimes of triplet 1,4-biradicals from Norrish-Type-II reactions." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 12,17 (2006): 4662-7. doi: https://doi.org/10.1002/chem.200600011
Cai X, Cygon P, Goldfuss B, Griesbeck AG, Heckroth H, Fujitsuka M, Majima T. Alpha-carbonyl substituent effect on the lifetimes of triplet 1,4-biradicals from Norrish-Type-II reactions. Chemistry. 2006 Jun 02;12(17):4662-7. doi: 10.1002/chem.200600011. PMID: 16557627.
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RETRACTED ARTICLE: Combination Antiemetic Regimens for Prevention of Postoperative Nausea and Vomiting : Focus on High-Risk Patients.

Clinical drug investigation

Fujii Y.
PMID: 29492850
Clin Drug Investig. 2002 Sep;22(9):561-574. doi: 10.2165/00044011-200222090-00001.

None of the available antiemetics is entirely effective, perhaps because most of them act through the blockade of one receptor. There is a possibility that a combination of antiemetics with different sites of activity would be more effective than...

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Fujii Y. RETRACTED ARTICLE: Combination Antiemetic Regimens for Prevention of Postoperative Nausea and Vomiting : Focus on High-Risk Patients. Clin Drug Investig. 2002;22(9):561-574doi: 10.2165/00044011-200222090-00001.
Fujii, Y. (2002). RETRACTED ARTICLE: Combination Antiemetic Regimens for Prevention of Postoperative Nausea and Vomiting : Focus on High-Risk Patients. Clinical drug investigation, 22(9), 561-574. https://doi.org/10.2165/00044011-200222090-00001
Fujii, Yoshitaka. "RETRACTED ARTICLE: Combination Antiemetic Regimens for Prevention of Postoperative Nausea and Vomiting : Focus on High-Risk Patients." Clinical drug investigation vol. 22,9 (2002): 561-574. doi: https://doi.org/10.2165/00044011-200222090-00001
Fujii Y. RETRACTED ARTICLE: Combination Antiemetic Regimens for Prevention of Postoperative Nausea and Vomiting : Focus on High-Risk Patients. Clin Drug Investig. 2002 Sep;22(9):561-574. doi: 10.2165/00044011-200222090-00001. PMID: 29492850.
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