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Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity.

Metabolism: clinical and experimental

Matsuzawa-Nagata N, Takamura T, Ando H, Nakamura S, Kurita S, Misu H, Ota T, Yokoyama M, Honda M, Miyamoto K, Kaneko S.
PMID: 18640384
Metabolism. 2008 Aug;57(8):1071-7. doi: 10.1016/j.metabol.2008.03.010.

Insulin resistance is a key pathophysiological feature of metabolic syndrome. However, the initial events triggering the development of insulin resistance and its causal relations with dysregulation of glucose and fatty acids metabolism remain unclear. We investigated biological pathways that...

Coronary Artery Disease and Diabetes Mellitus.

Heart failure clinics

Aronson D, Edelman ER.
PMID: 26567979
Heart Fail Clin. 2016 Jan;12(1):117-33. doi: 10.1016/j.hfc.2015.08.010.

Diabetes mellitus (DM) is a major risk factor for cardiovascular disease. Near-normal glycemic control does not reduce cardiovascular events. For many patients with 1- or 2-vessel coronary artery disease, there is little benefit from any revascularization procedure over optimal...

Selective allosteric antibodies to the insulin receptor for the treatment of hyperglycemic and hypoglycemic disorders.

Journal of diabetes science and technology

Issafras H, Bedinger DH, Corbin JA, Goldfine ID, Bhaskar V, White ML, Rubin P, Scannon PJ.
PMID: 24876415
J Diabetes Sci Technol. 2014 Jul;8(4):865-73. doi: 10.1177/1932296814529886. Epub 2014 Apr 07.

Many therapeutic monoclonal antibodies act as antagonists to receptors by targeting and blocking the natural ligand binding site (orthosteric site). In contrast, the use of antibodies to target receptors at allosteric sites (distinct from the orthosteric site) has not...

Combination therapy in type 2 diabetes mellitus: adding empagliflozin to basal insulin.

Drugs in context

Ahmann A.
PMID: 26633984
Drugs Context. 2015 Nov 11;4:212288. doi: 10.7573/dic.212288. eCollection 2015.

Type 2 diabetes mellitus (T2DM) management is complex, with few patients successfully achieving recommended glycemic targets with monotherapy, most progressing to combination therapy, and many eventually requiring insulin. Sodium glucose cotransporter 2 (SGLT2) inhibitors are an emerging class of...

Nutrition attributes and health effects of pistachio nuts.

The British journal of nutrition

Bulló M, Juanola-Falgarona M, Hernández-Alonso P, Salas-Salvadó J.
PMID: 26148925
Br J Nutr. 2015 Apr;113:S79-93. doi: 10.1017/S0007114514003250.

Epidemiological and/or clinical trials have suggested that nut consumption has a beneficial impact on health outcomes such as hypertension, diabetes, CVD, cancer, other inflammatory conditions and total mortality. Nuts are nutrient-dense foods with a healthy fatty acid profile, as...

How fast can glucose be infused in the perioperative setting?.

Perioperative medicine (London, England)

Hahn RG.
PMID: 26759716
Perioper Med (Lond). 2016 Jan 11;5:1. doi: 10.1186/s13741-015-0027-7. eCollection 2016.

BACKGROUND: How the initial infusion rate of glucose solution should be set to avoid hyperglycemia in the perioperative setting is unclear.METHODS: Computer simulations were performed based on data from seven studies where the kinetics of glucose was calculated using...

Short-Term Effects of Lupin vs. Whey Supplementation on Glucose and Insulin Responses to a Standardized Meal in a Randomized Cross-Over Trial.

Frontiers in physiology

Schopen K, Ewald AC, Johannes BW, Bloch W, Rittweger J, Frings-Meuthen P.
PMID: 28443026
Front Physiol. 2017 Apr 10;8:198. doi: 10.3389/fphys.2017.00198. eCollection 2017.

No abstract available.

Acute metabolic response to fasted and postprandial exercise.

International journal of general medicine

de Lima FD, Correia AL, Teixeira Dda S, da Silva Neto DV, Fernandes ÍS, Viana MB, Petitto M, da Silva Sampaio RA, Chaves SN, Alves ST, Dantas RA, Mota MR.
PMID: 26316800
Int J Gen Med. 2015 Aug 13;8:255-60. doi: 10.2147/IJGM.S87429. eCollection 2015.

The aim of this study was to analyze the acute metabolic response to exercise in fasting and postprandial. For this, ten individuals were submitted to an incremental treadmill test, with an initial speed of 5 and 1 km/h increments...

Steroid-induced hyperglycaemia in hospitalised patients: does it matter?.


Cheung NW.
PMID: 27677766
Diabetologia. 2016 Dec;59(12):2507-2509. doi: 10.1007/s00125-016-4116-z. Epub 2016 Sep 27.

Steroid-induced hyperglycaemia is a common problem faced by endocrinologists in hospital wards. In this issue of Diabetologia, Popovic and colleagues (DOI 10.1007/s00125-016-4091-4 ) have conducted a subanalysis within a randomised controlled trial of prednisone therapy for community-acquired pneumonia. The...

Effects of Moderate Glycemic Control in Type II Diabetes With Insulin on Arterial Blood Gas Parameters Following Coronary Artery Bypass Graft Surgery.

Research in cardiovascular medicine

Masoumi G, Frasatkhish R, Jalali A, Ziyaeifard M, Sadeghpour-Tabae A, Mansouri M.
PMID: 25478539
Res Cardiovasc Med. 2014 May;3(2):e17857. doi: 10.5812/cardiovascmed.17857. Epub 2014 May 10.

BACKGROUND: Coronary artery bypass grafting (CABG) is one of the common surgeries in patients with coronary artery disease (CAD). It is more probable for patients with diabetes to undergo surgeries due to CAD and they have a higher mortality...

Management of intraocular hypertension during hemodialysis by intravenous glucose administration.

American journal of kidney diseases : the official journal of the National Kidney Foundation

Saritas T, Koutsonas A, Walter P, Floege J, Krüger T.
PMID: 24189474
Am J Kidney Dis. 2014 Mar;63(3):500-2. doi: 10.1053/j.ajkd.2013.08.034. Epub 2013 Nov 01.

A 64-year-old woman with end-stage renal disease and retinopathy secondary to type 2 diabetes mellitus presented with recurrent episodes of left ocular pain and acute loss of visual acuity during hemodialysis. During these episodes, markedly elevated intraocular pressures were...

Psychosocial job factors and biological cardiovascular risk factors in Mexican workers.

American journal of industrial medicine

Garcia-Rojas IJ, Choi B, Krause N.
PMID: 25678459
Am J Ind Med. 2015 Mar;58(3):331-51. doi: 10.1002/ajim.22410.

BACKGROUND: Psychosocial job factors (PJF) have been implicated in the development of cardiovascular disease. The paucity of data from developing economies including Mexico hampers the development of worksite intervention efforts in those regions.METHODS: This cross-sectional study of 2,330 Mexican...

Showing 1 to 12 of 205696 entries