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Showing 1 to 12 of 56 entries
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Hypercoagulability in hereditary hemorrhagic telangiectasia with epilepsy.

Journal of neurosciences in rural practice

Finsterer J, Sehnal E.
PMID: 26167029
J Neurosci Rural Pract. 2015 Jul-Sep;6(3):407-9. doi: 10.4103/0976-3147.158791.

Recent data indicate that in patients with hereditary hemorrhagic teleangiectasia (HHT), low iron levels due to inadequate replacement after hemorrhagic iron losses are associated with elevated factor-VIII plasma levels and consecutively increased risk of venous thrombo-embolism. Here, we report...

Inhibition of blood coagulation factors by serine esterase inhibitors.

FEBS letters

De Lange JA, Hemker HC.
PMID: 11946685
FEBS Lett. 1972 Aug 15;24(3):265-268. doi: 10.1016/0014-5793(72)80369-7.

No abstract available.

Blood coagulation factors V and VIII: Molecular Mechanisms of Procofactor Activation.

Journal of coagulation disorders

Bos MH, Camire RM.
PMID: 21165149
J Coagul Disord. 2010 Jul 01;2(2):19-27.

A hallmark of hemostasis is that cells and proteins involved in the formation of a blood clot remain in a quiescent state and are only activated following an appropriate stimulus. The homologous proteins factors V and VIII cannot participate...

Hereditary thrombophilic risk factors for recurrent pregnancy loss.

Journal of community genetics

Bogdanova N, Markoff A.
PMID: 22460204
J Community Genet. 2010 Jun;1(2):47-53. doi: 10.1007/s12687-010-0011-3. Epub 2010 Jun 11.

This review summarizes current knowledge about the role of hereditary hypercoagulation factors predisposing to thrombophilia-associated recurrent fetal loss. Thrombophilias are a major cause of adverse pregnancy outcome, playing a role in the etiology of up to 40% of cases...

Vitamin K: the effect on health beyond coagulation - an overview.

Food & nutrition research

Vermeer C.
PMID: 22489224
Food Nutr Res. 2012;56. doi: 10.3402/fnr.v56i0.5329. Epub 2012 Apr 02.

Vitamin K is essential for the synthesis of proteins belonging to the Gla-protein family. To the members of this family belong four blood coagulation factors, which all are exclusively formed in the liver. The importance of vitamin K for...

Blood coagulation induced by Iranian saw-scaled viper (echis carinatus) venom: identification, purification and characterization of a prothrombin activator.

Iranian journal of basic medical sciences

Babaie M, Salmanizadeh H, Zolfagharian H.
PMID: 24494066
Iran J Basic Med Sci. 2013 Nov;16(11):1145-50.

OBJECTIVE(S): Echis carinatus is one of the venomous snakes in Iran. The venom of Iranian Echis carinatus is a rich source of protein with various factors affecting the plasma protein and blood coagulation factor. Some of these proteins exhibit...

Evaluation of the plasma quality after filtration.

Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences

Mahmoodian Shooshtari M, Mousavi Hosseini K.
PMID: 22615604
Daru. 2010;18(2):114-7.

BACKGROUND AND THE PURPOSE OF THE STUDY: The quality of some of the human plasma derived drugs such as coagulation factor VIII and coagulation factor IX which can be used for the treatment of hemophilia A and B, depends...

Hemostasis in Overt and Subclinical Hyperthyroidism.

International journal of endocrinology and metabolism

Ordookhani A, Burman KD.
PMID: 29201071
Int J Endocrinol Metab. 2017 Apr 23;15(3):e44157. doi: 10.5812/ijem.44157. eCollection 2017 Jul.

CONTEXT: There are contradictory results on the effect of hyperthyroidism on hemostasis. Inadequate population-based studies limited their clinical implications, mainly on the risk of venous thromboembolism (VTE). The present review focuses on hemostatic changes in overt and subclinical hyperthyroidism.METHODS:...

Hematuria in aging men with hemophilia: Association with factor prophylaxis.

Research and practice in thrombosis and haemostasis

Qvigstad C, Tait RC, de Moerloose P, Holme PA.
PMID: 32110762
Res Pract Thromb Haemost. 2020 Jan 16;4(2):309-317. doi: 10.1002/rth2.12298. eCollection 2020 Feb.

INTRODUCTION: Macroscopic hematuria is considered a significant risk factor for urologic disease, and it is highly prevalent in people with hemophilia.AIM: To determine whether prophylactic factor replacement therapy is associated with reduced occurrence of macroscopic hematuria in people with...

An efficient and effective ambulatory service model for severe hemophilia-A patients; an introduction to a novel home care model.

American journal of blood research

Davari M, Sadeghi A, Gharibnaseri Z, Ravanbod R, Eshghi P, Zargaran M.
PMID: 34824884
Am J Blood Res. 2021 Oct 15;11(5):520-527. eCollection 2021.

INTRODUCTION: Hemophilia A (HA) is an inherited deficiency in blood coagulation factors. Starting the treatment based merely on patients' hemorrhage feelings results in more than 63.6% mistakes in joint bleeding diagnosis. This study aimed to design a useful ambulatory...

Clinical utilization of four-factor prothrombin complex concentrate: a retrospective single center study.

Clinical and experimental emergency medicine

Naeem Z, Allan S, Hernandez A, Galanakis DK, Singer AJ.
PMID: 34237811
Clin Exp Emerg Med. 2021 Jun;8(2):75-81. doi: 10.15441/ceem.20.017. Epub 2021 Jun 30.

OBJECTIVE: Four-factor prothrombin complex concentrate (4F-PCC) was approved by the US Food and Drug Administration in 2013 for management of severely bleeding patients on warfarin therapy. We describe use of 4F-PCC at a large, suburban academic center.METHODS: We retrospectively...

Evaluation of selected parameters of the coagulation system during the perioperative period in patients undergoing endoscopic surgery of the paranasal sinuses.

Archives of medical science : AMS

Urbaniak J, Owczarek K, Miłoński J, Pietkiewicz P, Jałocha-Kaczka A, Olszewski J.
PMID: 33224332
Arch Med Sci. 2018 Jan 04;16(6):1336-1345. doi: 10.5114/aoms.2017.72544. eCollection 2020.

INTRODUCTION: The aim of the study was to evaluate selected parameters of the coagulation system during the perioperative period in patients undergoing endoscopic sinus surgery.MATERIAL AND METHODS: The study involved 121 patients: group I - 42 patients who did...

Showing 1 to 12 of 56 entries