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Showing 1 to 12 of 4386 entries
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Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2

program evaluation

Bonifacio E.
GSID: 48igUZnRAzAJ
C Törn, PW Mueller, M Schlosser, E Bonifacio… - Diabetologia, 2008 - Springer

… The aims of the first DASP evaluation were to assess and improve comparability of islet autoantibody measurements among laboratories and to undertake extended evaluation of the new WHO international reference reagent for antibodies to GAD and IA-2 [8,...

The ITP syndrome: pathogenic and clinical diversity

diversity

Liebman HA.
GSID: Y0cjQnKIvsoJ
DB Cines, JB Bussel, HA Liebman… - Blood, The Journal of …, 2009 - ashpublications.org

Immune thrombocytopenia (ITP) is mediated by platelet autoantibodies that accelerate platelet destruction and inhibit their production. Most cases are considered idiopathic, whereas others are secondary to coexisting conditions. Insights from secondary forms suggest that the …

Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies

program evaluation

Bonifacio E.
GSID: JSvQx-iCH2YJ
M Schlosser, PW Mueller, C Törn, E Bonifacio… - Diabetologia, 2010 - Springer

Aims/hypothesis Insulin autoantibodies (IAA) are important in type 1 diabetes risk assessment. However, their determination varies more between laboratories than other diabetes autoantibodies. The Diabetes Antibody Standardization Program (DASP) aims to improve and …

Moxifloxacin-Induced Immune-Mediated Thrombocytopenia in a Chronic Kidney Disease Patient Receiving Hemodialysis.

The Annals of pharmacotherapy

Mailman JF, Stigant C, Martinusen D.
PMID: 24687544
Ann Pharmacother. 2014 Jul;48(7):919-922. doi: 10.1177/1060028014529929. Epub 2014 Mar 31.

OBJECTIVE: To alert clinicians to a serious complication from a commonly prescribed medication, moxifloxacin.CASE SUMMARY: A 65-year-old male, septic, hemodialysis patient developed thrombocytopenia following exposure to vancomycin, ceftazidime, and moxifloxacin. Drug-specific immunoglobulin testing showed positive autoantibodies against only moxifloxacin,...

Clinicopathological analysis of mechanic's hand associated with dermatomyositis.

The Australasian journal of dermatology

Mori T, Ohashi T, Kato Y, Ohtsuka M, Yamamoto T.
PMID: 26299387
Australas J Dermatol. 2016 Nov;57(4):e123-e126. doi: 10.1111/ajd.12381. Epub 2015 Aug 23.

Mechanic's hand is often seen in the fingers of patients with dermatomyositis and is frequently associated with anti-aminoacyl-transfer RNA synthetase autoantibodies and interstitial lung disease. We analysed the clinical symptoms of 50 patients with dermatomyositis who had visited our...

Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.

JCI insight

Kienhöfer D, Hahn J, Stoof J, Csepregi JZ, Reinwald C, Urbonaviciute V, Johnsson C, Maueröder C, Podolska MJ, Biermann MH, Leppkes M, Harrer T, Hultqvist M, Olofsson P, Munoz LE, Mocsai A, Herrmann M, Schett G, Holmdahl R, Hoffmann MH.
PMID: 28515366
JCI Insight. 2017 May 18;2(10). doi: 10.1172/jci.insight.92920. eCollection 2017 May 18.

Many effector mechanisms of neutrophils have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). Neutrophil extracellular traps (NETs) have been assigned a particularly detrimental role. Here we investigated the functional impact of neutrophils and NETs on a...

Aptamers in Therapeutics.

Journal of clinical and diagnostic research : JCDR

Parashar A.
PMID: 27504277
J Clin Diagn Res. 2016 Jun;10(6):BE01-6. doi: 10.7860/JCDR/2016/18712.7922. Epub 2016 Jun 01.

Aptamers are single strand DNA or RNA molecules, selected by an iterative process known as Systematic Evolution of Ligands by Exponential Enrichment (SELEX). Due to various advantages of aptamers such as high temperature stability, animal free, cost effective production...

Anti-HMGCR Autoantibodies in Juvenile Idiopathic Inflammatory Myopathies Identify a Rare but Clinically Important Subset of Patients.

The Journal of rheumatology

[No authors listed]
PMID: 28864670
J Rheumatol. 2017 Sep;44(9):1417. doi: 10.3899/jrheum.160871.C1.

No abstract available.

New-Onset Refractory Status Epilepticus with Claustrum Damage: Definition of the Clinical and Neuroimaging Features.

Frontiers in neurology

Meletti S, Giovannini G, d'Orsi G, Toran L, Monti G, Guha R, Kiryttopoulos A, Pascarella MG, Martino T, Alexopoulos H, Spilioti M, Slonkova J.
PMID: 28396650
Front Neurol. 2017 Mar 27;8:111. doi: 10.3389/fneur.2017.00111. eCollection 2017.

New-onset refractory status epilepticus (NORSE) is a rare but challenging condition occurring in a previously healthy patient, often with no identifiable cause. We describe the electro-clinical features and outcomes in a group of patients with NORSE who all demonstrated...

Serum Protein Profile in Women With Pregnancy Morbidity Associated With Antiphospholipid Syndrome.

Journal of human reproductive sciences

Alvarez AM, Neubeck S, Parra S, Markert UR, Cadavid AP.
PMID: 28479750
J Hum Reprod Sci. 2017 Jan-Mar;10(1):10-17. doi: 10.4103/0974-1208.204018.

CONTEXT: Antiphospholipid antibodies (aPL) are related with a high risk of pregnancy morbidity (PM) and also of vascular thrombosis. On the basis of recent studies, we expect that in women with PM associated with antiphospholipid syndrome (APS), further factors...

Clinical and histopathological features of myopathies in Japanese patients with anti-SRP autoantibodies.

Modern rheumatology

Takada T, Hirakata M, Suwa A, Kaneko Y, Kuwana M, Ishihara T, Ikeda Y.
PMID: 28925310
Mod Rheumatol. 2009 Apr;19(2):165. doi: 10.3109/s10165-009-0165-1.

No abstract available.

In vivo imaging reveals rapid astrocyte depletion and axon damage in a model of neuromyelitis optica-related pathology.

Annals of neurology

Herwerth M, Kalluri SR, Srivastava R, Kleele T, Kenet S, Illes Z, Merkler D, Bennett JL, Misgeld T, Hemmer B.
PMID: 26946517
Ann Neurol. 2016 May;79(5):794-805. doi: 10.1002/ana.24630. Epub 2016 Apr 18.

OBJECTIVE: Neuromyelitis optica (NMO) is an autoimmune disease of the central nervous system, which resembles multiple sclerosis (MS). NMO differs from MS, however, in the distribution and histology of neuroinflammatory lesions and shows a more aggressive clinical course. Moreover,...

Showing 1 to 12 of 4386 entries