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Showing 1 to 12 of 372 entries
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Ion suppression effect in desorption electrospray ionization and electrospray ionization mass spectrometry.

Rapid communications in mass spectrometry : RCM

Wang Z, Zhu H, Huang G.
PMID: 28857292
Rapid Commun Mass Spectrom. 2017 Dec 15;31(23):1957-1962. doi: 10.1002/rcm.7977.

RATIONALE: Although it is claimed that desorption electrospray ionization (DESI) causes less ion suppression effects than electrospray ionization (ESI), a related investigation with quantification measurement of ion suppression effects is absent. Herein, a comparative analysis of ion suppression effects...

Sheathless interface to match flow rate of capillary electrophoresis with electrospray mass spectrometry using regular-sized capillary.

Rapid communications in mass spectrometry : RCM

Yin Y, Li G, Guan Y, Huang G.
PMID: 27539418
Rapid Commun Mass Spectrom. 2016 Aug;30:68-72. doi: 10.1002/rcm.7621.

RATIONALE: The flow rate match has been a great challenge when coupling capillary electrophoresis (CE) with electrospray ionization mass spectrometry (ESI-MS). Conventional CE-ESI-MS interfaces used liquid sheath flow, narrowed capillary or additional pressure to meet this requirement; sacrifice of...

Deprotonation effect of tetrahydrofuran-2-carbonitrile buffer gas dopant in ion mobility spectrometry.

Rapid communications in mass spectrometry : RCM

Fernandez-Maestre R, Meza-Morelos D, Wu C.
PMID: 27173115
Rapid Commun Mass Spectrom. 2016 Jun 15;30(11):1332-8. doi: 10.1002/rcm.7567.

RATIONALE: When dopants are introduced into the buffer gas of an ion mobility spectrometer, spectra are simplified due to charge competition.METHODS: We used electrospray ionization to inject tetrahydrofuran-2-carbonitrile (F, 2-furonitrile or 2-furancarbonitrile) as a buffer gas dopant into an...

A double-blind crossover comparison of pindolol, metoprolol, atenolol and labetalol in mild to moderate hypertension.

British journal of clinical pharmacology

McNeil JJ, Louis WJ.
PMID: 26635160
Br J Clin Pharmacol. 1979 Apr;8:163S-6S. doi: 10.1111/j.1365-2125.1979.tb04774.x.

1 This study was designed to compare in a double-blind randomized crossover trial, atenolol, labetalol, metoprolol and pindolol. Considerable differences in dose (atenolol 138 +/- 13 mg daily; labetalol 308 +/- 34 mg daily; metoprolol 234 +/- 22 mg...

Evaluation of the antioxidant properties of the angiotensin-converting enzyme inhibitor, captopril and the nucleotide enhancing agent, acadesine.

Redox report : communications in free radical research

Wasil M, Kelly FJ.
PMID: 27405835
Redox Rep. 1995 Nov;1(5):361-7. doi: 10.1080/13510002.1995.11747012.

The angiotensin-converting enzyme inhibitor, captopril and the nucleotide enhancing agent, acadesine, protect myocardial tissue from ischaemia/reperfusion-induced injury. Although both drugs have well established, independent mechanisms of cardiac protection, they may also have antioxidant activity which could contribute to their...

Formulation and evaluation of mouth disintegrating tablets of atenolol and atorvastatin.

Indian journal of pharmaceutical sciences

Sarfraz RM, Khan HU, Mahmood A, Ahmad M, Maheen S, Sher M.
PMID: 25767322
Indian J Pharm Sci. 2015 Jan-Feb;77(1):83-90. doi: 10.4103/0250-474x.151602.

In this study, mouth-disintegrating tablets of atenolol and atorvastatin combination were formulated using superdisintegrants to impart fast disintegration. Fifteen formulations were prepared based on different concentrations of two superdisintegrants, croscarmellose sodium and Kyron-T134. Three different techniques such as direct...

Assessment of drug-drug interactions in hypertensive patients at a superspeciality hospital.

Avicenna journal of medicine

Sivva D, Mateti UV, Neerati VM, Thiruthopu NS, Martha S.
PMID: 25878964
Avicenna J Med. 2015 Apr-Jun;5(2):29-35. doi: 10.4103/2231-0770.154194.

OBJECTIVE: The objective of the study was to assess the incidence and pattern of drug-drug interactions (DDIs) in hypertensive patients by using Micromedex and Medscape databases.MATERIALS AND METHODS: A prospective observational study was carried out in a superspeciality hospital...

Is it time to replace propranolol with carvedilol for portal hypertension?.

World journal of gastrointestinal endoscopy

Abid S, Ali S, Baig MA, Waheed AA.
PMID: 25992192
World J Gastrointest Endosc. 2015 May 16;7(5):532-9. doi: 10.4253/wjge.v7.i5.532.

Beta-adrenergic receptor antagonists (β-blockers) have been well established for use in portal hypertension for more than three decades. Different Non-selective β-blockers like propranolol, nadolol, timolol, atenolol, metoprolol and carvedilol have been in clinical practice in patients with cirrhosis. Carvedilol...

Postmarketing pharmacokinetic and pharmacodynamic equivalence of generic and brand atenolol in Egypt.

Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit

Badawi MA, Wagdy E, Nasr M, Etman MA, El-Khordagui LK, Khalil SA.
PMID: 24995741
East Mediterr Health J. 2014 Jan 09;19:S166-71.

Concerns have been raised regarding the postmarketing quality of generic drugs. This study assessed the pharmacokinetic and pharmacodynamic equivalence of generic and brand atenolol tablets in 24 healthy male volunteers in a single-dose, open, randomized, two-period crossover study under...

Modifying the Interagency Emergency Health Kit to include treatment for non-communicable diseases in natural disasters and complex emergencies.

BMJ global health

Tonelli M, Wiebe N, Nadler B, Darzi A, Rasheed S.
PMID: 28588970
BMJ Glob Health. 2016 Oct 20;1(3):e000128. doi: 10.1136/bmjgh-2016-000128. eCollection 2016.

The Interagency Emergency Health Kit (IEHK) provides a standard package of medicines and simple medical devices for aid agencies to use in emergencies such as disasters and armed conflicts. Despite the increasing burden of non-communicable diseases (NCDs) in such...

Atenolol Reduces Leishmania major-Induced Hyperalgesia and TNF-α Without Affecting IL-1β or Keratinocyte Derived Chemokines (KC).

Frontiers in pharmacology

Karam MC, Merckbawi R, Salman S, Mobasheri A.
PMID: 26913003
Front Pharmacol. 2016 Feb 15;7:22. doi: 10.3389/fphar.2016.00022. eCollection 2016.

Infection with a high dose of the intracellular parasitic protozoan Leishmania major induces a sustained hyperalgesia in susceptible BALB/c mice accompanied by up-regulation of the pro-inflammatory cytokines IL-1β and IL-6. Interleukin-13 (IL-13) has been shown to reduce this hyperalgesia...

β-Blockers in hypertension, diabetes, heart failure and acute myocardial infarction: a review of the literature.

Open heart

DiNicolantonio JJ, Fares H, Niazi AK, Chatterjee S, D'Ascenzo F, Cerrato E, Biondi-Zoccai G, Lavie CJ, Bell DS, O'Keefe JH.
PMID: 25821584
Open Heart. 2015 Mar 21;2(1):e000230. doi: 10.1136/openhrt-2014-000230. eCollection 2015.

β-Blockers (BBs) are an essential class of cardiovascular medications for reducing morbidity and mortality in patients with heart failure (HF). However, a large body of data indicates that BBs should not be used as first-line therapy for hypertension (HTN)....

Showing 1 to 12 of 372 entries